SUBSTANTIATION OF THE EFFECTIVENESS OF A COMPREHENSIVE ALGORITHM OF ORTHOPEDIC REHABILITATION FOR THE PREVENTION OF PATHOLOGY OF THE ORAL MUCOSA

Author(s):  
Жанна Владимировна Вечеркина ◽  
Алина Александровна Смолина ◽  
Марина Николаевна Бобешко ◽  
Наталья Александровна Шалимова ◽  
Евгения Олеговна Лещева

Актуальность : известно, что съемные ортопедические конструкции зубных протезов на протяжении долгого времени являются сложными раздражителями слизистой оболочки полости рта (СОПР). Грамотное выполнение технологических этапов изготовления, своевременная коррекция, рекомендации по профессиональной и индивидуальной гигиене полости рта и самих зубных протезов не всегда гарантируют отсутствие микробной колонизации на поверхности базисов условно-патогенными и патогенными представителями и воспалительной реакции со стороны тканей протезного ложа. При выборе базисного материала в качестве замещающей и восстанавливающей конструкции и при ортопедическом лечении в целом перед врачом-стоматологом встает вопрос о профилактике осложнений дисбиотического и воспалительного характера. Целью настоящего исследования является изучение влияния базисного материала съемных ортопедических конструкций на состояние тканей протезного ложа и доказательство эффективности предложенного авторами комплексного метода профилактики дисбиоза полости рта, влияющего на успех всего протезирования и качество стоматологического здоровья. Методика исследования: в клинике ортопедической стоматологии пациенты, нуждающиеся в съемном протезировании, были сформированы на 3 равноценные группы исследования, каждой из которых был предложен определенный алгоритм лечебно - профилактических мероприятий. Для решения поставленной задачи на предмет эффективности авторской методики далее использовали методику макрогистохимической реакции, что позволило оценить состояние слизистой оболочки под базисами съёмных протезов из акрилового полимера через сутки, 7 и 14 дней наложения съемного зубного протеза, также изучали количественный и качественный состав микробиоциноза слизистой оболочки полости рта. Результаты исследования: результаты клинико-микробиологического исследования слизистой оболочки протезного ложа указывают на целесообразность применения предложенной авторами методики ортопедической реабилитации для профилактики дисбиоза полости рта. Заключение : исследования, направленные на изучение данных проблем, особенно важны для повышения эффективности ортопедической реабилитации для снижения стоматологических осложнений у пациентов воспалительного и дисбиотического характера Relevance: it is known that removable orthopedic structures of dentures for a long time are complex irritants of the oral mucosa (SOPR). Competent implementation of the technological stages of manufacturing, timely correction, recommendations for professional and individual hygiene of the oral cavity and the dentures themselves do not always guarantee the absence of microbial colonization on the surface of the bases by conditionally pathogenic and pathogenic representatives and an inflammatory reaction from the tissues of the prosthetic bed. When choosing a basic material as a replacement and restoring structure and during orthopedic treatment in general, the dentist faces the question of preventing complications of a dysbiotic and inflammatory nature. The purpose of this study is to study the influence of the basic material of removable orthopedic structures on the state of the prosthetic bed tissues and to prove the effectiveness of the complex method of prevention of oral dysbiosis proposed by the authors, which affects the success of all prosthetics and the quality of dental health. Research methodology: in the clinic of orthopedic dentistry, patients in need of removable prosthetics were formed into 3 equivalent study groups, each of which was offered a certain algorithm of therapeutic and preventive measures. To solve the problem for the effectiveness of the author's technique, the method of macrohistochemical reaction was further used, which made it possible to assess the state of the mucous membrane under the bases of removable dentures made of acrylic polymer after a day, 7 and 14 days of applying a removable denture, and the quantitative and qualitative composition of microbiocinosis of the oral mucosa was also studied. Results of the study : the results of clinical and microbiological examination of the mucous membrane of the prosthetic bed indicate the expediency of using the method of orthopedic rehabilitation proposed by the authors for the prevention of oral dysbiosis. Conclusion: studies aimed at studying these problems are especially important for improving the effectiveness of orthopedic rehabilitation to reduce dental complications in patients of an inflammatory and dysbiotic nature

Author(s):  
Наталия Александровна Полушкина ◽  
Наталия Владимировна Чиркова ◽  
Наталья Владимировна Примачева ◽  
Елена Александровна Лещева ◽  
Ольга Игоревна Олейник

Факторами, способствующими возникновению гипертрофического воспаления слизистой оболочки полости рта при пользовании конструкциями съемных протезов, являются механическая травма, плохая гигиена рта и ослабление резистентности организма. Отмечено, что при устранении причины, а именно при отказе от пользования съемными пластиночными протезами, воспалительные явления исчезают. Анализ литературы показал, что тяжесть течения воспалительных заболеваний тканей полости рта зависит от различных факторов, в том числе от состояния иммунологической резистентности и обсемененности тканей микроорганизмами. Учеными была установлена взаимосвязь между клиническими параметрами, иммунологическими показателями ротовой жидкости и состоянием микробиоценоза рта. Доказано, что для полости рта, как и для всего организма, свойственна микробная флора, которая отличается постоянством качественного и количественного состава флоры. Известно, что она поддерживается физиологическими процессами, обеспечивающими оптимальное функционирование слизистой оболочки и слюнных желез, взаимоотношениями между микробными видами, что является следствием биологического равновесия за счет феномена «бактериального взаимодействия», как между организмом и адаптированной флорой, так и между отдельными ее видами. Учеными доказано, что нормальная микробная флора, осуществляя функции биологического барьера и постоянного стимулятора локального иммунитета, оказывает положительное влияние на организм. Однако при изменении соотношения отдельных видов под влиянием разнообразных причин, микробная флора утрачивает свои защитные свойства и часто становится источником аутоинфекции. Доказано, что травма, возникающая при ношении съемных протезов, влияет на эту среду и способствует росту патогенной флоры, которая является причиной возникновения заболеваний слизистой оболочки рта, таких как протезный стоматит, кандидоз Factors contributing to the occurrence of hypertrophic inflammation of the oral mucosa when using removable denture structures are mechanical trauma, poor oral hygiene and weakening of the body's resistance. It is noted that when the cause is eliminated, namely, when refusing to use removable plate prostheses, inflammatory phenomena disappear. The analysis of the literature showed that the severity of the course of inflammatory diseases of the oral tissues depends on various factors, including the state of immunological resistance and the contamination of the tissues with microorganisms. Scientists have established the relationship between clinical parameters, immunological parameters of oral fluid and the state of oral microbiocenosis. It is proved that the oral cavity, as well as the entire body, is characterized by microbial flora, which is characterized by a constant qualitative and quantitative composition of the flora. It is known that it is supported by physiological processes that ensure optimal functioning of the mucous membrane and salivary glands, the relationship between microbial species, which is a consequence of the biological balance due to the phenomenon of "bacterial interaction", both between the organism and the adapted flora, and between its individual species. Scientists have proven that the normal microbial flora, performing the functions of a biological barrier and a permanent stimulator of local immunity, has a positive effect on the body. However, when the ratio of individual species changes under the influence of various causes, the microbial flora loses its protective properties and often becomes a source of auto-infection. It is proved that the trauma that occurs when wearing removable dentures affects this environment and promotes the growth of pathogenic flora, which is the cause of diseases of the oral mucosa, such as prosthetic stomatitis, candidiasis


2018 ◽  
Vol 14 (2) ◽  
pp. 60-65
Author(s):  
Ganesh Prasad Neupane ◽  
Maya Rai ◽  
R. S. Rathore ◽  
V. K. Bhargava ◽  
A. K. Mahat ◽  
...  

Introduction: Oral Submucous Fibrosis (OSMF) is a precancerous condition of the oral mucosa. It is characterized by excessive production of collagen leading to inelasticity of the oral mucosa and atrophic changes of the epithelium.Aim and objective: To evaluate the efficacy of oral Colchicine in comparison to intralesional injections of Dexamethasone plus Hyaluronidase in the management of OSMF patients.Materials and Methods: Fourty patients with OSMF were randomly divided equally into two groups. 20 patients in Dexamethasone group received biweekly intralesional injections of Dexamethasone (4mg/ml) plus Hyaluronidase 1500 IU in buccal mucosa for a period of 12 weeks. Other 20 patients in Colchicine group received oral Colchicine 0.5 mg tablets twice daily for 12 weeks. Parameters taken in the study were burning sensation, and mouth opening. Descriptive statistics, paired t test and unpaired t test were used for statistical analysis.Results and Conclusions: The pre- and post-treatment differences were found to be statistically significant for both the groups (p<0.001) and for both the treatment outcomes. When the average difference of the treatment outcomes was compared between the two study groups, statistically highly significant difference was noted (p <0.001) only in mouth opening but not in burning sensation.These encouraging results should prompt further clinical trials with Colchicine on a larger sample size to broaden the therapeutic usefulness of the drug in the management of OSMF. JNGMC,  Vol. 14 No. 2 December 2016, Page: 60-65


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hiroki Hihara ◽  
Ryo Tagaino ◽  
Jumpei Washio ◽  
Kittipong Laosuwan ◽  
Dimas Prasetianto Wicaksono ◽  
...  

Abstract Background Removal of oral biofilm from the oral mucosa is essential for preventing risk of respiratory and gastrointestinal infection in elderly people. Currently, no device is available which can remove oral biofilm from oral mucosa effectively and safely. Therefore, the effectiveness and safety of the Micro Scale Mist UNIT (MSM-UNIT), a newly developed dental plaque removal device utilizing high speed sprays of fine water droplets, were evaluated for biofilm removal, including the rate and surface roughness for simulated tooth surface and mucous membrane. Methods Simulated tooth and oral mucosa coated with an artificial biofilm of Streptococcus mutans were used for evaluation of effectiveness, with uncoated substrates as the controls. The MSM-UNIT and a conventional air ablation device were operated under recommended instructions. The effectiveness was evaluated from the rate of removal of the biofilm, and the safety was evaluated from the damage observed by scanning electron microscope and surface roughness. Results The biofilm removal rate of the MSM-UNIT was significantly higher than that of AIRFLOW. Little damage was observed in the area treated by the MSM-UNIT. The surface roughness of the MSM-UNIT treated area on simulated tooth surface and oral mucosa showed no significant difference to the control area. In contrast, cracks and powder were observed in the area treated by AIRFLOW. In particular, the surface roughness of the AIRFLOW treated area for Toughsilon was significantly larger than that of the control. Conclusions The MSM-UNIT could be used safely and effectively for removing biofilm not only on simulated tooth surfaces but also simulated mucous membrane. The MSM-UNIT has no harmful effect on teeth or oral mucosa, and may be used for comprehensive oral care for patients during nursing care and the perioperative period.


2012 ◽  
Vol 13 (4) ◽  
pp. 456-459 ◽  
Author(s):  
Bhushan Arun Jawale ◽  
Rahul Redasani ◽  
Lalit Chaudhari ◽  
Narendra Chopde ◽  
Amol Pharande ◽  
...  

ABSTRACT Aim To determine microbial prevalence in the mucous membrane and prosthesis of denture wearers with and without denture stomatitis and to study its relationship with potential clinical cofactors. Materials and methods Saliva was collected from 200 patients (100 female and 100 male) wearing dental prosthesis for measurement of pH. Oral samples of the mucous membrane and of dentures were taken with sterile swab for microbiological analysis. Medical and dietary history of the subjects was recorded. Chi-square test and analysis of varience were used for statistical analysis. Results Diabetes, hypertension and high carbohydrate ingestion was observed in majority of patients. The pH average in saliva was of 5.1. The presence of C. albicans, S. aureus and S. mutans in the mucous membrane was of 55.4, 56.4 and 63.6% respectively. C. albicans was isolated in 69.7% from the prosthesis, whereas S. aureus and S. mutans were isolated in 45.3%. The isolation of C.albicans was more frequent in patients with deture stomatitis. Conclusion C. albicans, S. aureus and S. mutans frequently colonize the oral mucous of denture wearers. This is more frequently observed in patients with denture stomatitis. Clinical significance Denture stomatitis is associated to Candida albicans, different bacteria and other cofactors, such as salivary pH, carbohydrate ingestion, systemic illnesses and medication. How to cite this article Chopde N, Jawale B, Pharande A, Chaudhari L, Hiremath V, Redasani R. Microbial Colonization and their Relation with Potential Cofactors in Patients with Denture Stomatitis. J Contemp Dent Pract 2012;13(4):456-459.


2017 ◽  
Vol 23 (1) ◽  
Author(s):  
Bohdan Lyubomyrovych Henyk ◽  
Mykola Mykhaylovych Rozko

The clinical examination of condition of tissues prosthetic bed was conducted in 20 patients with  pemphigus vulgaris. The results are compared with survey data of 20 persons of control group without somatic pathology. It was conducted the analyzes of subjective and objective assessment of tissues prosthetic bed, the results of clinical examination and frequency of various pathologies of the oral mucosa membrane in the studied groups, conducted the comparative evaluation of dental indicators.


2021 ◽  
Vol 31 (1) ◽  
pp. 111-112
Author(s):  
Roberto Maglie ◽  
Corinne Orsini ◽  
Beatrice Bianchi ◽  
Emiliano Antiga ◽  
Elisa Cinotti

2019 ◽  
Vol 15 (3) ◽  
pp. 206-210
Author(s):  
Vinay Marla ◽  
Dharanidhar Baral ◽  
Prabhat Ranjan Pokharel ◽  
Ashish Shrestha ◽  
Rajesh Gyawali ◽  
...  

Introduction: Fixed orthodontic treatment causes chronic low grade irritation on the oral mucosa. Tobacco smoking is considered to be a risk factor in the development of oral cancer. This study involves a cytomorphometric analysis on the buccal mucosal cells in patients undergoing fixed orthodontic treatment who are tobacco smokers. Methods: Exfoliated buccal mucosal cells were obtained from orthodontic patients (smokers & non-smokers) as well as smokers and non-smokers who are not undergoing any orthodontic treatment. Smears were stained with rapid PAP stain and digital images of 50 cells were analysed using the Image J software. Results: Statistical analysis revealed that there were significant increase in the values of nuclear and cell diameter between non-smokers undergoing orthodontic treatment and smokers (p<0.001 & p=0.014 respectively), and between non-smokers undergoing orthodontic treatment and smokers undergoing orthodontic treatment (p<0.001 & p=0.015 respectively). Also, nuclear area and cell area showed significant differences between many of the study groups. Conclusion: It can be concluded that there are nuclear and cellular alterations in patients undergoing fixed orthodontic treatment who are smokers


2019 ◽  
pp. 16-20
Author(s):  
T.P. Skrypnіkova ◽  
P.M. Skrypnikov

Leptotrichia species play an important role in the microflora composition of the oral cavity, a genus of asporogenous gram-negative anaerobic bacteria, in the form of sticks that belong to the family of Fusobakterium. According to the morphological data, the structure of the cell wall, antigenic structure, they are part of the opportunistic flora of the oral cavity. Their peculiarities are the sensitivity to the toxic effects of oxygen, the absence of spores, the complexity of food processes. It also allows to refer them to the family of lactic acid bacteria that promote lactic acid fermentation. Violation of homeostasis in the oral cavity and the presence of somatic diseases lead to the transformation of leptotrichia from the category of opportunistic microflora into pathogenic one. Different opinions about approaches to treatment in the presence of leptotrichia in the oral cavity are expressed. Some authors say that abundantly vegetative leptotrichia do not indicate pathology. Others, on the contrary, have the opposite view, believing that leptotrichosis is a disease close to opportunistic mycosis. But there is the third opinion: some authors attribute leptotrichosis to HIV - associated diseases. Clinical similarities with other fungal infections make it difficult to manage these patients. There are some important traits for differential diagnosis such as identified symptoms, in some cases the lack of effectiveness of previous or current treatment, postponed and concomitant diseases, sociodemographic status, use of medicines. Subjective, objective and additional examination methods were used for diagnosis. Objective examination of patients was carried out according to the recommendations of experts of the World Health Organization (WHO). As additional method of examination it has been used microscopic research, which was the most effective, clinical analysis of blood, urine, blood for sugar. If necessary, patients were referred for consultation to other specialists. Candidiasis of the oral mucosa has a code ICD - B.370. Patients have such complaints as burning of the mucous membrane of the lips, cheeks, hard and soft palate, dry mouth. There is a coarse keratinized epithelium of filamentous papillae, which gives them the appearance of spiky, pointed, very dense growths of gray or yellowish-gray color. The plaque may cover some areas of the oral mucosa. It adheres tightly to the tissues, is difficult to remove, exposing a loose bleeding surface. Inflammation is not identified. The mucous membrane appearance is worried patients, they examine it several times a day, which causes a phobia. In some cases, the filamentous papillae of the tongue may be atrophied, it becomes smooth, but the color of the mucosa is not changed. Patients suffer from eating spicy food. Among all diagnostic methods (subjective and objective) only the microscopic one is effective. Leptotrichosis accounts for 5 cases (4.09%) of the examined 122 patients with fungal origin stomatitis. This disease is quite rare, only a few clinical cases are described in the literature. The pathogenesis of the disease (incomplete cellular immunity, shift of the phagocytic activity of neutrophils, monocytes, eosinophils, the host sensitization of leptotrichia’s byproducts, high saccharolytic activity, and others) is considered in leptotrichosis management. Leptotrichosis of the oral cavity mucosa is characterized by a chronic course (for several months). The treatment plan is made with an internist. A dentist has to know different alternative kind of treatment. Patients should be examined dynamically.


Author(s):  
Denys Zagirniak ◽  
Oleg Kratt ◽  
Mykhaylo Zagirnyak

Topicality of the research subject. The government authorities are concerned about higher education as human capital is being formed in this area.This concern is lessening as macroeconomic indicators show a lack of economic opportunities. Statement of the problem. Limited state funding for higher education requires improved spending of budget funds. Analysis of the recent research and publications. The state funding of higher education is considered at the macro- and micro levels from different angles. Selection of the unresearched parts of the general problem. There is no link between state funding of higher education at the macro level and the use of government funds at the micro level. Statement of the task and the purpose of the research. The method for the assessment of the finance provision of higher education has been improved, which makes it possible to achieve congruence between the mechanism of state order and the choice of educational services by consumers. Method or methodology of the research. A method for assessing the effectiveness of the financial provision of higher education in the space that has the parameters of “educational degree” and “field of knowledge” has been proposed. Statement of the basic material (results of the work). The low effectiveness of the use of state financial resources in relation to specialties and institutions of higher education of Poltava region has been determined. In the segment of “junior specialists” 113 places of the state order were not selected, and in the segment of “bachelors” – 98 places of state order. For most specialties in the segments the license amount did not correspond to the amount of state orders. The segments of the market of educational services differed significantly as to the state order. In the segment of “junior specialists” the share of the state budget places in the amount of demand was 85.16%, the share in the segment of “bachelors” – 60.24%, and in the segment of “masters” –  36.17%. The state stimulated potential consumers with the help of the state order to buy educational services. The state did not fund the realization of the HEI potential, encouraging them to commercialize educational programs. Field of application of results. The field of higher education. Conclusions. The proposed assessment methodology enables determining the effectiveness of the use of the state financial resources for specialties and institutions of higher education and the selection of possible alternative models for the distribution of the state order for their further financing.


Sign in / Sign up

Export Citation Format

Share Document