Analysis of the toxicological situation in Moscow in the first three months of the COVID-19 pandemic

2021 ◽  
Vol 29 (5) ◽  
pp. 49-57
Author(s):  
Anastasiya Yurevna Simonova ◽  
Pavel Gennadevich Rozhkov ◽  
Mariya Vladimirovna Belova ◽  
Kapitolina Konstsntinovna Ilyashenko ◽  
Mikhail Mikhaylovich Potskhveriya ◽  
...  
Keyword(s):  
Emergency Medicine ◽  
Medical Care ◽  
Acute Poisoning ◽  
Hospitalized Patients ◽  
Toxic Effects ◽  
Alcohol Poisoning ◽  
Working Age ◽  
Coronavirus Infection ◽  
Restrictive Measures ◽  
The Impact

Introduction. On March 11, 2020, WHO announced the global COVID-19 pandemic. According to literature data, the spread of coronavirus infection COVID-19 affected the structure of acute chemical poisoning. The aim. Assessment of the impact of the COVID-19 pandemic and restrictive measures on the peculiarities of seeking advice and the structure of acute chemical poisoning in Moscow. Material and methods. The data of the registration forms “Card of recording of a consultation of a patient with acute poisoning of chemical etiology” in the period from March 30 to June 30, 2020 and 2019 were studied. The analysis indicators of a hospitalization of patients in the department of acute poisoning and somatopsychiatric disorders of N.V. Sklifosovsky, the Research Institute of Emergency Medicine. Results. It was found that in the analyzed period of 2020 compared to 2019, the proportion of injured people of working age decreased by 11.2%, while it increased at the age of 0-17 years by 3.2 times. An increase in the number of consultations for individuals by 2.1 times was noted. There was an increase in the number of complaints about poisoning with antibiotics, drugs from the T45 group (anticoagulants, vitamins, etc.), T37 (antiviral, anti-microbial, etc.) by 1.7-2 times. In March-June 2020, there was an increase in the number of complaints about the toxic effects of alcohol (T51), an increase in hospitalized patients with acute alcohol poisoning by 4 times, and with combined alcohol poisoning - by 2.7 times. The number of complaints about poisoning with detergents and disinfectants in the first three months of the pandemic increased by 2.7 times. Conclusion. The pandemic and the introduction of restrictive measures for COVID-19 have affected the toxicological situation in Moscow, which must be taken into account when determining the guidelines for organizational measures for the provision of medical care for acute chemical poisoning during the COVID-19 pandemic.

Changes in the procedure for financial support of medical organizations in the system of compulsory medical insurance at the present stage of the spread of coronavirus infection (

2020 ◽  
pp. 67-74
Author(s):  
F. N. Kadyrov ◽  
◽  
O. V. Obukhova ◽  
A. M. Chililov ◽  
◽  
...  
Keyword(s):  
Medical Care ◽  
Financial Support ◽  
Preventive Measures ◽  
Medical Insurance ◽  
Number Of Factors ◽  
Coronavirus Infection ◽  
The Russian Federation ◽  
The One ◽  
Restrictive Measures ◽  
The Cost

In the context of the spread of coronavirus infection, the main problem of medical organizations is not an obvious increase in the cost of providing medical care associated with ensuring the sanitary and epidemiological regime (personal protective equipment, disinfection, etc.), but a decrease in income due to a drop in the volume of planned medical care, suspension of preventive measures, downtime (during the period of re-profiling, etc.). The state quickly responded to this situation by making changes to the relevant legislation and adopting a number of special regulatory legal acts. However, the implementation of these rather varied measures tied to a number of factors, such as the presence or absence of restrictive measures on the territory of the Russian Federation; participation or non-participation in the care of patients with coronavirus infection; periods within which the one or the other order advances, etc. All this causes difficulties in understanding what financial security mechanism is applied to this particular situation, what should be the actions of medical organizations. This article is devoted to the analysis of ways of financial support of medical organizations in the system of compulsory medical insurance at various stages of the fight against coronavirus infection.

scholarly journals Depression during the COVID-19 pandemic (analysis of clinical cases)

2021 ◽  
Vol 13 (1) ◽  
pp. 81-86
Author(s):  
I. Yu. Dorozhenok
Keyword(s):  
Female Patient ◽  
Depressive Disorders ◽  
Therapy Regimen ◽  
History Of ◽  
Coronavirus Infection ◽  
Restrictive Measures ◽  
The Impact ◽  
Financial Losses ◽  
Clinical Cases

Currently, in various world regions, the prevalence of depressive and anxiety disorders due to the impact of coronavirus infection is repeatedly increased compared to that in previous years. Among the predictors of their development during the pandemic, there are COVID-19 symptoms, a history of mental disorders, as well as restrictive measures, and financial losses.The paper describes three clinical cases of depressive disorders during the COVID-19 pandemic, with the depiction of the anamnesis, somatic and mental status, the patholopsychogical qualification of the condition, and the justification of a therapy regimen. The multifactorial stressor effect of the COVID-19 pandemic has provoked an exacerbation of depression in a male patient with a history of affective disorder; the development of a nosogenic depressive reaction of demoralization in a female patient with coronavirus pneumonia; the worsening of somatization dysthymia in a female patient of involutional age. The timely recognition of depression and its treatment with currently available antidepressants have contributed to the achievement of high-quality remission, the increase of stress resistance, and the improvement of quality of life in the patients.

scholarly journals The impact of the pandemic on the structure of income and expenditure of the consolidated budgets of the constituent entities of the Russian Federation of the Ural Federal District

2020 ◽  
Vol 12 (5) ◽  
Author(s):  
Ekaterina Zakharchuk ◽  
Aleksey Pasynkov ◽  
Polina Trifonova
Keyword(s):  
Russian Federation ◽  
Federal District ◽  
Scientific Methods ◽  
General Scientific ◽  
Coronavirus Infection ◽  
The Russian Federation ◽  
Restrictive Measures ◽  
Regional Budgets ◽  
Social Expenditures ◽  
The Impact

The article is devoted to the assessment of changes in the budgets of the constituent entities of the Russian Federation that are part of the Ural Federal District, which they have undergone in connection with the change in the macroeconomic situation in the country and regions. The article provides an overview of scientific research on the topic under consideration. On the basis of open official data, using general scientific methods, the influence of the introduced restrictive measures related to the fight against the spread of coronavirus infection on the regional budgets of the constituent entities of the Russian Federation of the Ural Federal District is shown. The analysis is carried out in the context of the structure of sources of formation of budget revenues, as well as in the areas of spending financial resources of the regions of the Ural Federal District, an assessment of the balance of the studied budgets is given. Comparative analysis was carried out for the first half of 2019 and 2020. The results obtained indicate that in the revenue part of the studied budgets of the constituent entities of the Russian Federation, tax revenues from profits and incomes have significantly decreased. All the regional budgets under consideration show an increase in gratuitous receipts. In the expenditure part of the budgets, the increase is mainly noted in the sections "Healthcare" and "Social policy". Thus, measures of state support in the first half of 2020 made it possible to maintain a budget surplus in four of the six subjects of the Russian Federation of the Ural Federal District. However, the current situation with the spread of coronavirus infection does not allow making optimistic forecasts for the further filling of the revenues of regional budgets. The situation is similar with the expenditure side – they will increase due to the growth of social expenditures, which will affect the balance of regional budgets.

scholarly journals Healthcare Service In The "Dentistry" Profle To The Population Of Moscow Under Restrictive Measures Of Covid-19

2021 ◽  
Vol 19 (2) ◽  
pp. 121-125
Author(s):  
A. Mitronin ◽  
A. Eremin ◽  
D. Ostanina
Keyword(s):  
Medical Care ◽  
Dental Care ◽  
Healthcare Service ◽  
Medical Insurance ◽  
Emergency Medical Care ◽  
Dental Services ◽  
Dental Equipment ◽  
Coronavirus Infection ◽  
In The Beginning ◽  
Restrictive Measures

In the beginning of the COVID-19 pandemic in March 2020, by the decree of the Mayor of Moscow, the provision of dental services to the population was temporarily suspended, with the exception of diseases and conditions requiring emergency or urgent dental care. A Headquarters was established to coordinate the provision of emergency and urgent dental care for COVID-19 patients and for those who was in isolation during lockdown. The Moscow Healthcare Department has been organized an activity of mobile medical and nursing teams (MNT) to provide emergency medical care in the "dentistry" profle. All MNTs were equipped with portable dental equipment. The MNTs has been working for free within the framework of compulsory medical insurance. For the period from March 26 to June 16 – 2020, medical care was provided to 1501 patients, of which 294 with a confrmed diagnosis of COVID-19, including 57 children. The measures taken were of a temporary nature and were aimed at preserving the health of Moscow residents and preventing the further spread of the new coronavirus infection COVID-19 in Moscow.

scholarly journals Analysis of the 2020 crisis and its consequences in the Kaluga region

2020 ◽  
Vol 7 (3) ◽  
Author(s):  
Nikolay Komarov ◽  
Tatiana Kondratenkova
Keyword(s):  
Regional Economy ◽  
Health Sector ◽  
Regional Administration ◽  
Force Majeure ◽  
Methods Of Synthesis ◽  
Economic State ◽  
Coronavirus Infection ◽  
Kaluga Region ◽  
Restrictive Measures ◽  
The Impact

The end of 2019 will be remembered for the discovery of the new coronavirus infection COVID-19, which has become a major challenge for all of humanity. The ongoing pandemic has provoked a crisis in all spheres of life and is continuously changing the global economic, political, social and other processes, forcing us to adapt to the introduced precautions. Using a logical and systematic approach to research, applying methods of synthesis and content analysis of the press, electronic media and communication, as well as scientific articles, the authors analyzed the impact of the COVID-19 coronavirus infection pandemic on the economic state of the Kaluga Region. The main socio-economic indicators are considered in dynamics and the most important spheres of the region's economy are analyzed in more detail. Assumptions have been made about how the restrictive measures designed to reduce the growth of cases affected the life-supporting processes of the region. The migration processes of the population were considered, and the change in the standard of living was assessed. How the coronavirus has affected the health sector is reflected. It has been analyzed whether the forecast of industrial production can be realized taking into account the current conditions. Taking into account the fact that a cluster model of development is being implemented in the region, the current indicators of the two leading directions: pharmaceutical and automotive, and their possibilities for the restoration of the regional economy with their help are reviewed. It was revealed that in the local Kaluga production of a large international pharmaceutical company, it is possible to implement part of the research to create a vaccine against coronavirus infection COVID-19. Based on the data processed in this article, it can be concluded that the diversification of the regional economy, which the regional administration adheres to, is bearing fruit in the current force majeure conditions. And the clustering of industry and preferential terms of permission for investors in such times have become especially relevant.

scholarly journals Analysis of the composition of hospitalized patients with the new coronavirus infection COVID-19

2021 ◽  
Vol 65 (3) ◽  
pp. 183-190
Author(s):  
Igor S. Kitsul ◽  
Valery I. Vechorko ◽  
Dmitry V. Kats ◽  
Dmitry A. Sychev
Keyword(s):  
Medical Care ◽  
Prognostic Value ◽  
Large Scale ◽  
Age Groups ◽  
Hospital Setting ◽  
Hospitalized Patients ◽  
Point Of View ◽  
Coronavirus Infection ◽  
Almost All ◽  
First Time

Introduction. In the context of the growing epidemic of the new coronavirus infection COVID-19, the Russian health system, for the first time in recent history, faced the need for large-scale mobilization and conversion of many existing hospitals into infectious diseases hospitals. At the same time, the composition of hospitalized patients has not been studied, and the availability of data on it is crucial for the organization and planning of medical care. Purpose of study. To study the composition of hospitalized patients with a new coronavirus infection COVID-19 from the point of view of their age, gender, the severity of the condition, the presence of pneumonia and concomitant diseases to optimize the planning and objectification of the assessment of the need for medical care in a hospital setting. Material and methods. The data was studied, and the analysis of hospitalizations of 1037 patients in the country’s largest repurposed infectious hospital for the treatment of patients with the new coronavirus infection COVID-19 was carried out. Results. For the first time analyzed the main regularities of the formation of hospitalized patients, which characterize features of the disease and have a high prognostic value both from the point of view of organization of specialized medical care in stationary conditions and assess the need for diagnostic and diagnostic and treatment activities and their resource provision. It is established that adult patients of almost all age groups receive medical care in a hospital setting, but as the age increases, the need for hospitalization tends to increase. Conclusions. The severity of hospitalized patients with COVID-19 is determined by their age and the presence of concomitant pathology, which is of important prognostic value from the point of view of optimal planning of this type of medical care.

scholarly journals Efficacy of Hydroxychloroquine and Tocilizumab in Patients With COVID-19: Single-Center Retrospective Chart Review (Preprint)

2020 ◽  
Author(s):  
Sohaib Roomi ◽  
Waqas Ullah ◽  
Faizan Ahmed ◽  
Soban Farooq ◽  
Usama Sadiq ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Renal Failure ◽  
Acute Renal Failure ◽  
Hospital Mortality ◽  
Medical Care ◽  
Invasive Mechanical Ventilation ◽  
Hospitalized Patients ◽  
Odds Ratios ◽  
Significant Difference ◽  
The Impact

BACKGROUND During the initial phases of the COVID-19 pandemic, there was an unfounded fervor surrounding the use of hydroxychloroquine (HCQ) and tocilizumab (TCZ); however, evidence on their efficacy and safety have been controversial. OBJECTIVE The purpose of this study is to evaluate the overall clinical effectiveness of HCQ and TCZ in patients with COVID-19. We hypothesize that HCQ and TCZ use in these patients will be associated with a reduction in in-hospital mortality, upgrade to intensive medical care, invasive mechanical ventilation, or acute renal failure needing dialysis. METHODS A retrospective cohort study was performed to determine the impact of HCQ and TCZ use on hard clinical outcomes during hospitalization. A total of 176 hospitalized patients with a confirmed COVID-19 diagnosis was included. Patients were divided into two comparison groups: (1) HCQ (n=144) vs no-HCQ (n=32) and (2) TCZ (n=32) vs no-TCZ (n=144). The mean age, baseline comorbidities, and other medications used during hospitalization were uniformly distributed among all the groups. Independent <i>t</i> tests and multivariate logistic regression analysis were performed to calculate mean differences and adjusted odds ratios with 95% CIs, respectively. RESULTS The unadjusted odds ratio for patients upgraded to a higher level of care (ie, intensive care unit) (OR 2.6, 95% CI 1.19-5.69; <i>P</i>=.003) and reductions in C-reactive protein (CRP) level on day 7 of hospitalization (21% vs 56%, OR 0.21, 95% CI 0.08-0.55; <i>P</i>=.002) were significantly higher in the TCZ group compared to the control group. There was no significant difference in the odds of in-hospital mortality, upgrade to intensive medical care, need for invasive mechanical ventilation, acute kidney failure necessitating dialysis, or discharge from the hospital after recovery in both the HCQ and TCZ groups compared to their respective control groups. Adjusted odds ratios controlled for baseline comorbidities and medications closely followed the unadjusted estimates. CONCLUSIONS In this cohort of patients with COVID-19, neither HCQ nor TCZ offered a significant reduction in in-hospital mortality, upgrade to intensive medical care, invasive mechanical ventilation, or acute renal failure needing dialysis. These results are similar to the recently published preliminary results of the HCQ arm of the Recovery trial, which showed no clinical benefit from the use of HCQ in hospitalized patients with COVID-19 (the TCZ arm is ongoing). Double-blinded randomized controlled trials are needed to further evaluate the impact of these drugs in larger patient samples so that data-driven guidelines can be deduced to combat this global pandemic.

scholarly journals The Quality of Medical Care in the Conditions of the COVID-19 Pandemic, with Particular Emphasis on the Access to Primary Healthcare and the Effectiveness of Treatment in Poland

2021 ◽  
Vol 10 (16) ◽  
pp. 3502
Author(s):  
Magdalena Kludacz-Alessandri ◽  
Renata Walczak ◽  
Liliana Hawrysz ◽  
Piotr Korneta
Keyword(s):  
Patient Satisfaction ◽  
Medical Care ◽  
Primary Healthcare ◽  
Treatment Effectiveness ◽  
Healthcare Services ◽  
Remote Healthcare ◽  
Considerable Impact ◽  
Restrictive Measures ◽  
The Impact

Health has a significant influence on the quality of life of a society. The COVID-19 pandemic has forced many countries to implement restrictive measures to prevent its wider spread, including, inter alia, the introduction of remote healthcare in the form of teleconsultations. Therefore, there is the question of how such a change affects the quality of treatment and the primary healthcare of patients during the COVID-19 pandemic. The article aims to examine patient satisfaction with the access to primary healthcare and the effectiveness of treatment in a condition of remote medical care caused by the COVID-19 pandemic. We also analyse the impact of access to primary healthcare on the treatment effectiveness. Patient satisfaction was measured using a questionnaire assessing the quality of primary medical care. Of the 36 items studied, seven were related to the accessibility dimension and four were related to the treatment effectiveness dimension. Our results suggest that the treatment effectiveness and the access to primary healthcare services during the COVID-19 pandemic through telemedicine are quite highly rated by patients. Hence, further implementation of telemedicine in primary healthcare should improve the quality of lives of the wide society. We have also identified the access to primary healthcare has a considerable impact on the treatment effectiveness. Therefore, we recommend increasing the contact between patients and GPs via telemedicine under lockdown conditions.

Labor Market Transformation in the COVID-19 Pandemic: Differentiation of the Impact of Physical and Information Virus Spread

2021 ◽  
pp. 83-102
Author(s):  
D.G. Rodionov ◽  
E.A. Konnikov ◽  
A.S. Ivanova
Keyword(s):  
Labor Market ◽  
Labour Force ◽  
Economic Effects ◽  
Economic Consequences ◽  
Russian Society ◽  
Market Transformation ◽  
Coronavirus Infection ◽  
Physical Consequences ◽  
Restrictive Measures ◽  
The Impact

Currently, the need to develop measures to prevent the negative economic consequences of the COVID-19 pandemic is primary for most countries in the world. Determining the ways of possible impact on the physical and informational form of the spread of a new coronavirus infection seems to be especially relevant in the context of a global problem. The purpose of this study is to analyze the impact of the physical and informational forms of the spread of coronavirus infection on the set of indicators characterizing the labor market, e.g. the unemployment rate, average wages in different types of economic activity, employer's need for the labour force; to identify the logic of behaviorof the Russian society by studying the dynamics of search queries in January--August 2020; to identify possible ways to minimize negative economic effects caused by the coronavirus pandemic. As a result of the study carried out within the labor market, a fundamentally new property of the pandemic was revealed --- the "effect of delaying physical consequences", the multidirectional influence of the physical and informational forms of the coronavirus spread on a number of indicators characterizing the labor market was established. The rapid adaptation of the Russian society to remote employment in lockdown and severe restrictive measures has been confirmed

scholarly journals Disease Severity and Prognosis of SARS-CoV-2 Infection in Hospitalized Patients Is Not Associated With Viral Load in Nasopharyngeal Swab

2021 ◽  
Vol 8 ◽  
Author(s):  
Elisabetta Cocconcelli ◽  
Gioele Castelli ◽  
Francesco Onelia ◽  
Enrico Lavezzo ◽  
Chiara Giraudo ◽  
...  
Keyword(s):  
Viral Load ◽  
Medical Care ◽  
Disease Severity ◽  
High Intensity ◽  
Hospitalized Patients ◽  
Nasopharyngeal Swab ◽  
Asymptomatic Individuals ◽  
The Right ◽  
Asymptomatic Subjects ◽  
The Impact

Background: The impact of viral burden on severity and prognosis of patients hospitalized for Coronavirus Disease 2019 (COVID-19) is still a matter of debate due to controversial results. Herein, we sought to assess viral load in the nasopharyngeal swab and its association with severity score indexes and prognostic parameters.Methods: We included 127 symptomatic patients and 21 asymptomatic subjects with a diagnosis of SARS-CoV-2 infection obtained by reverse transcription polymerase chain reaction and presence of cycle threshold. According to the level of care needed during hospitalization, the population was categorized as high-intensity (HIMC, n = 76) or low intensity medical care setting (LIMC, n = 51).Results: Viral load did not differ among asymptomatic, LIMC, and HIMC SARS-CoV-2 positive patients [4.4 (2.9–5.3) vs. 4.8 (3.6–6.1) vs. 4.6 (3.9–5.7) log10 copies/ml, respectively; p = 0.31]. Similar results were observed when asymptomatic individuals were compared to hospitalized patients [4.4 (2.9–5.3) vs. 4.68 (3.8–5.9) log10 copies/ml; p = 0.13]. When the study population was divided in High (HVL, n = 64) and Low Viral Load (LVL, n = 63) group no differences were observed in disease severity at diagnosis. Furthermore, LVL and HVL groups did not differ with regard to duration of hospital stay, number of bacterial co-infections, need for high-intensity medical care and number of deaths. The viral load was not an independent risk factor for HIMC in an adjusted multivariate regression model (OR: 1.59; 95% CI: 0.46–5.55, p = 0.46).Conclusions: Viral load at diagnosis is similar in asymptomatic and hospitalized patients and is not associated with either worse outcomes during hospitalization. SARS CoV-2 viral load might not be the right tool to assist clinicians in risk-stratifying hospitalized patients.

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