scholarly journals Faktor Risiko Paritas Terhadap Kejadian Bayi Berat Lahir Rendah (BBLR) di Puskesmas Jongaya Makassar Tahun 2020

2020 ◽  
Vol 4 (1) ◽  
pp. 26-31
Author(s):  
Idha Farahdiba ◽  
Novia Novia

Berdasarkan data dari catatan medical record Puskesmas Jongaya Makassar bahwa pada periode Januari s.d Juli 2020 terdapat 145 ibu bersalin, dengan jumlah bayi berat lahir normal adalah sebesar 130 orang (89,66%) dan jumlah bayi berat lahir rendah (BBLR) adalah sebesar 11 orang (10,34%). Tujuan dari penelitian ini adalah untuk mengetahui besar faktor risiko paritas terhadap kejadian bayi berat lahir rendah (BBLR) di Puskesmas Jongaya Makassar 2020. Penelitian ini menggunakan jenis penelitian rancangan survey analitik dengan pendekatan case control untuk mengetahui besar faktor risiko paritas terhadap kejadian bayi berat lahir rendah (BBLR) di Puskesmas Jongaya Makassar Tahun 2020. Teknik pengambilan sampel dengan menggunakan teknik total sampling. Penelitian ini terdiri dari populasi kelompok kasus dan kontrol dengan total sebanyak 145 orang. Dimana jumlah sampel kasus sebanyak 13 orang sehingga digunakan perbandingan sampel kasus dan kontrol adalah 1 : 3. Jadi besar sampel secara keseluruhan adalah sebanyak 52 sampel, dimana dalam pemilihan sampel menggunakan matching umur 20-35 tahun. Dari hasil uji statistik dengan menggunakan rumus Odds Ratio (OR), diperoleh nilai OR 4,500 pada CI 95% 1,163-17,409. Karena nilai OR >1 serta lower limit dan upper limit >1 artinya paritas merupakan faktor risiko yang signifikan terhadap kejadian BBLR sehingga diharapkan kepada ibu untuk ikut serta dalam program keluarga berencana (KB) untuk menurukan angka kejadian kematian ibu dan bayi.

2020 ◽  
Vol 4 (2) ◽  
pp. 110-115
Author(s):  
Ikrawanty Ayu Wulandari ◽  
Adinda Nur Fadillah

Asfiksia merupakan kegagalan bernafas secara spontan segera setelah bayi lahir dan berisiko untuk terjadinya kematian, keadaan janin tidak dapat bernafas spontan dan teratur sehingga dapat menurunkan oksigen dan makin meningkatkan karbondioksida yang menimbulkan dampak buruk dalam kehidupan berlanjut. Penelitian ini menggunakan jenis penelitian rancangan survey analitik dengan pendekatan case control yang digunakan untuk mengetahui penyebab penyakit dengan menginvestigasi hubungan antara faktor risiko dengan kejadian penyakit (Swarjana, 2015). Kemudian mengidentifikasi Hubungan Risiko Umur Ibu Terhadap Kejadian Asfiksia Di RS Umum Bahagia Makassar. Penelitian ini dilakukan dengan mengambil data medical record di RSU Bahagia Makassar pada bulan Januari – Mei 2020 . Populasi pada penelitian ini adalah seluruh bayi yang lahir di RSU Bahagia Makassar pada tahun 2020 yang berjumlah 512 bayi. Pengambilan sampel dilakukan dengan teknik case control dalam penelitian ini jumlah sampel sebanyak 38 sampel kasus dan 38 sampel control. Berdasarkan uji statistik diperoleh nilai OR yaitu 1.000 pada    CI 95% 0,332 – 3,013, artinya hubungan umur resiko tinggi terhadap kejadian asfiksia hanya 1 kali lebih besar dibandingkan dengan Ibu yang resiko rendah . Karena OR=1 serta lower limit <1 dan upper limit >1 maka faktor umur bukan merupakan faktor yang signifikan terhadap kejadian asfiksia. Kesimpulan dari variabel umur ibu yaitu faktor umur bukan merupakan faktor yang signifikan terhadap kejadian asfiksia di RS Umum Bahagia Makassar.  


2020 ◽  
Vol 4 (1) ◽  
pp. 8-14
Author(s):  
St Subriani ◽  
Warda Ningsih

Berdasarkan catatan Medical Record RSU Bahagia Makassar Periode Januari s.d Desember 2019, terdapat 991 ibu yang melahirkan dan yang terdiagnosa KPD 29 orang (2,92 %) dan jumlah bayi yang lahir Periode Januari s.d Desember 2019 sebanyak 995 orang dan yang mengalami asfiksia 38 orang (3,81 %). Periode Januari s.d Mei 2020, terdapat 510 ibu yang melahirkan dan yang terdiagnosa KPD 29 orang (5,68 %), dan jumlah bayi yang lahir Periode Januari s.d April 2020 sebanyak 512 orang dan yang mengalami asfiksia 38 orang (7,42%). Tujuan dilakukannya penelitian ini adalah untuk mengetahui besar faktor risiko terhadap kejadian asfiksia pada bayi baru lahir di RSU Bahagia Makassar tahun 2020. Teknik pengambilan sampel dengan menggunakan teknik total sampling. Penelitian ini terdiri dari populasi kelompok kasus dan kontrol dengan total sebanyak 511 orang. Dimana jumlah sampel kasus sebanyak 38 orang sehingga digunakan perbandingan sampel kasus dan kontrol adalah 1 : 1. Jadi besar sampel secara keseluruhan adalah sebanyak 76 sampel. Dari hasil uji statistik untuk faktor KPD dengan menggunakan rumus Odds Ratio (OR), diperoleh nilai OR yaitu  0,329 CI 95% 0,093 – 1,165. Karena OR < 1 serta nilai 1 berada diantara lower limit dan upper limit maka faktor KPD tidak berisiko terhadap kejadian asfiksia atau tidak signifikan. Dari hasil uji statistik untuk faktor Paritas dengan menggunakan rumus Odds Ratio (OR), diperoleh nilai OR yaitu  3,032 CI 95% 1,174-7,831. Karena OR > 1 serta lower limit dan upper limit > 1 maka faktor paritas merupakan faktor risiko yang signifikan terhadap kejadian Asfiksia. Kesimpulan dari dua variabel yaitu faktor KPD terdapat pengaruh yang tidak signifikan dengan kejadian Asfiksia dan faktor paritas terdapat hubungan yang signifikan dengan kejadian Asfiksia di RSU Bahagia Makassar Tahun 2020. Kemudian diharapkan ibu hamil dapat meningkatkan kunjungan ANC dan bagi peneliti selanjutnya agar melanjutkan penelitian ini dengan menggunakan variabel yang berbeda seperti preeklamsia, partus lama, lilitan tali pusat, dan premature terhadap kejadian Asfiksia.


Author(s):  
A. NURUL AMALIAH ◽  
AMI FEBRIZA

The aim of this research was to know about the correlation between cataract occurance with Diabetes Mellitus. This research was performed in Medical Record Departement of Balai Kesehatan Mata Masyarakat Makassar using medical record on the period of January 2016 to October 2016 with case control design, consist of 74 subjects which were divided into cataract as case, consist of 37 subjects and without cataract as control, consist of 37 subjects. Data of diabetes mellitus history were collected from patient medical recordand analyzed by Chi Square with the significance’s degree was p<0.05. The result showed moderate correlation between cataract occurance and diabetes mellitus (p=0.002) with Odds Ratio (OR) 4,563 (IC :1,683 – 12,371)KEYWORDS : Cataract, Diabetes Melitus


2019 ◽  
Vol 12 (2) ◽  
pp. 1-10
Author(s):  
La Rangki ◽  
Fitriani

Demam  tifoid  merupakan  penyakit  infeksi  akut  usus  halus  yang  disebabkan  oleh  bakteri  Salmonellathypi. Penelitian ini bertujuan untuk mengetahui apakah  sikap dan kebiasaan makan diluar rumah merupakan factor risiko kejadian demam typhoid di RSUD Kab.Muna. Responden  padapenelitian ini berjumlah 39 orang kelompok kasus dan 39 orang kelompok kontrol. Metode pengambilan data dilakukan  dengan  observasi  dan  kuesioner.  Uji  statistic  yang  digunakan  adalah  uji  chi-square  dengan  tingkat kemaknaan 95%. Data diolah secara univariat, bivariat, dan nilai odds ratio. Dari hasil penelitian menunjukan sikap dengan nilai OR=10,286, lower limit= 3,551,dan upper limit= 29,795. Kebiasaan makan di luar rumah  dengan nilai OR= 2,970, lower limit= 1,161, dan upper limit= 7,599. Sehingga dapat disimpulkan bahwa factor sikap dan kebiasaan makan diluar rumah merupakan factor risiko terjadinya demam tiphiod. Kata kunci : Sikap, Kebiasaan makan di luar rumah, Demam Typhoid


2018 ◽  
Vol 28 (7) ◽  
pp. 2165-2178
Author(s):  
Anqi Zhu ◽  
Donglin Zeng ◽  
Pengyue Zhang ◽  
Lang Li

One important goal in pharmaco-epidemiology studies is to understand the causal relationship between drug exposures and their clinical outcomes, including adverse drug events. In order to achieve this goal, however, we need to resolve several challenges. Most of pharmaco-epidemiology data are observational and confounding is largely present due to many co-medications. The pharmaco-epidemiology study data set is often sampled from large medical record databases using a matched case-control design, and it may not be representative of the original patient population in the medical record databases. Data analysis method needs to handle a large sample size that cannot be handled using existing statistical analysis packages. In this paper, we tackle these challenges both methodologically and computationally. We propose a conditional causal log-odds ratio (OR) definition to characterize causal effects of drug exposures on a binary adverse drug event adjusting for individual level confounders. Using a case-control design, we present a propensity score estimation using only case samples and we provide sufficient conditions for the consistency of the estimation of the causal log-odds ratio using case-based propensity scores. Computationally, we implement a principle component analysis to reduce high-dimensional confounders. Extensive simulation studies are performed to demonstrate superior performance of our method to existing methods. Finally, we apply the proposed method to analyze drug-induced myopathy data sampled from a de-identified subset of medical record database (close to 5 million patient records), The Indiana Network for Patient Care. Our method identified 70 drug-induced myopathy ( p < 0.05) out 72 drugs, which have myoathy side effects on their FDA drug labels. These 70 drugs include three statins who are known for their myopathy side effects.


2018 ◽  
Vol 15 (8) ◽  
pp. 723-730 ◽  
Author(s):  
Fidelia Bature ◽  
Dong Pang ◽  
Anthea Robinson ◽  
Norma Polson ◽  
Yannis Pappas ◽  
...  

Objective: Evidence suggests that individuals with Alzheimer’s disease (AD) are often diagnosed in the later stages of their disease with a poor prognosis. This study is aimed to identify patterns in signs and symptoms preceding the clinical diagnosis of AD to suggest a predictive model for earlier diagnosis of the disease in the primary care. Design: A retrospective medical record review; nested case control design. Participants: Participants included one hundred and nine patients from three general practice (GP) surgeries in Milton Keynes and Luton Clinical Commissioning Groups (CCG) (37 cases with AD and 72 controls without AD). Main outcome measure: A retrospective analysis using the logistic regression of the presence of signs and symptoms before the diagnosis of AD was attained. Identification of the timing and sequence of appearance of these presentations as first reported before the clinical diagnosis was measured. Result: Episodic memory with an odds ratio of 1.85 was the most frequent presentation, documented in 1.38% of the controls and 75.6% in cases. Auditory disturbance with an odds ratio of 3.03, which has not previously been noted except in the form of auditory hallucination, could have a diagnostic value. Conclusion: Auditory disturbance, which occurred mostly in the Caucasian females, could discriminate individuals with AD from those without the disease. The symptom, which presented up to 14.5 (mean time) years prior to clinical diagnosis, was identified in Caucasians and mixed race individuals only. Strengths: The study demonstrates that auditory disturbance could allow an earlier diagnosis of AD in Caucasian females. Episodic memory was confirmed as being frequently noted in AD patients prior to a clinical diagnosis as per previous publications. This study supports the development of a scoring system for the earlier diagnosis of AD. The data used was free from the confounding effects of misinformation, as this was written at the point of collection, thereby benefitting from the use of GP data that is diversified, reliable and valid. Limitations: Limited sample size that will not allow for generalization of less frequent observations due to their low prevalence in case notes. Randomisation was not achieved; however, the best available nonrandomisation which is consecutive sampling was used. Patterns identified were in LOAD, the baseline could vary with other geographical areas.


2018 ◽  
Vol 1 (2) ◽  
pp. 85
Author(s):  
Safrudin Tolinggi ◽  
Kasma Mantualangi ◽  
Nuryani Nuryani

AbstractOne cause of maternal morbidity and mortality is preeclampsia. The purpose of this research was to determine the risk factors of preeclampsia. The type of research was observational analytic using a case control study to determine risk factors for the incidence of preeclampsia in pregnant women. The population in this study as many as 1182 people and the sample size of 168 people consisting of case and control samples. Sampling technique was used purposive sampling. Results was showed that analysis unvariate parity 1 and > 3 as many as 62,5%, the distance of pregnancy < 2 years and > 5 years as many as 35,7% and education < 9 years as many as 33,3%. Analysis bivariate with odds ratio values obtained OR = 1.052, with a lower limit value (0.563) and the upper limit (1.965) then parity was significant risk factor on the incidence of preeclampsia. Results of statistical bivariate analysis OR = 2.088, with a lower limit value (1.096) and the upper limit (3.978) then the distance pregnancy was significant risk factor on the incidence of preeclampsia. Results of statistical bivariate analysis odds ratio values obtained OR = 1.239, with a lower limit value (0.652) and the upper limit (2.354) then education was a significant risk factor on the incidence of preeclampsia. The conclusion of this study was the parity, gap of pregnancy and education were the risk factor for preeclampsia in pregnant women.Keywords; age, education, gap of pregnancy, parity, preeclampsiaAbstrakSalah satu penyebab morbiditas dan mortalitas ibu adalah preeclampsia. Tujuan dalam penelitian ini adalah untuk mengetahui faktor risiko kejadian preeclampsia. Jenis penelitian yang digunakan adalah observasional analitik dengan menggunakan rancangan case control study untuk mengetahui faktor risiko kejadian preeklampsia pada ibu hamil. Populasi dalam penelitian ini sebanyak 1182 orang dan jumlah sampel 168 orang yang terdiri dari sampel kasus dan kontrol. Tehnik pengambilan sampel secara purposive sampling. Hasil penelitian menunjukkan analisis univariat paritas 1 dan > 3 sebanyak 62,5%, jarak kehamilan < 2 tahun dan > 5 tahun sebanyak 35,7% dan pendidikan < 9 tahun sebanyak 33,3%. Analisis bivariat dengan uji odds ratio diperoleh nilai OR=1,052, dengan nilai lower limit (0,563) dan upper limit (1,965) maka paritas merupakan faktor risiko yang bermakna terhadap kejadian preeklampsia. Hasil analisis statistik bivariat dengan uji odds ratio dengan nilai OR=2,088, dengan nilai lower limit (1,096) dan upper limit (3,978) maka jarak kehamilan merupakan faktor risiko yang bermakna terhadap kejadian preeklampsia. Hasil analisis statistik bivariat dengan uji odds ratio diperoleh nilai OR=1,239, dengan nilai lower limit (0,652) dan upper limit (2,354) maka pendidikan merupakan faktor risiko yang bermakna terhadap kejadian preeklampsia. Kesimpulan dari penelitian ini adalah paritas, jarak kehamilan dan pendidikan merupakan faktor risiko kejadian preeklampsia pada ibu hamil.Kata kunci; umur, jarak kehamilan, pendidikan, paritas, preeklmpsia


2020 ◽  
Vol 14 (2) ◽  
pp. 205-220
Author(s):  
Yuxiu Jiang ◽  
Xiaohuan Zhao

Background: The working state of electronic accelerator pedal directly affects the safety of vehicles and drivers. Effective fault detection and judgment for the working state of the accelerator pedal can prevent accidents. Methods: Aiming at different working conditions of electronic accelerator pedal, this paper used PNN and BP diagnosis model to detect the state of electronic accelerator pedal according to the principle and characteristics of PNN and BP neural network. The fault diagnosis test experiment of electronic accelerator pedal was carried out to get the data acquisition. Results: After the patents for electronic accelerator pedals are queried and used, the first measured voltage, the upper limit of first voltage, the first voltage lower limit, the second measured voltage, the upper limit of second voltage and the second voltage lower limit are tested to build up the data samples. Then the PNN and BP fault diagnosis models of electronic accelerator pedal are established. Six fault samples are defined through the design of electronic accelerator pedal fault classifier and the fault diagnosis processes are executed to test. Conclusion: The fault diagnosis results were analyzed and the comparisons between the PNN and the BP research results show that BP neural network is an effective method for fault detection of electronic throttle pedal, which is obviously superior to PNN neural network based on the experiment data.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Mariem Hajji-Louati ◽  
Emilie Cordina-Duverger ◽  
Nasser Laouali ◽  
Francesca-Romana Mancini ◽  
Pascal Guénel

AbstractDietary regimens promoting inflammatory conditions have been implicated in breast cancer development, but studies on the association between pro-inflammatory diet and breast cancer risk have reported inconsistent results. We investigated the association between the inflammatory potential of diet and breast cancer risk in a case–control study in France including 872 breast cancer cases and 966 population controls. All women completed a food frequency questionnaire that was used to compute a Dietary Inflammatory Index (DII) based on the inflammatory weight of 33 dietary components. The DII ranged from a median of − 3.22 in the lowest quartile (anti-inflammatory) to + 2.96 in the highest quartile (pro-inflammatory). The odds ratio contrasting quartile 4 to quartile 1 was 1.31 (95% CI 1.00, 1.73; p-trend = 0.02). Slightly higher odds ratios were observed in post-menopausal women, particularly those with body mass index > 25 kg/m2 (odds ratio 1.62; 95% CI 0.92, 2.83; p-trend = 0.02), and among ever smokers (odds ratio 1.71; 95% CI 1.11, 2.65; p-trend 0.01). The analyses by breast cancer subtype showed that the DII was associated with breast tumors that expressed either the estrogen (ER) or progesterone (PR) hormone receptors or the Human Epidermal Growth Factor Receptor-2 (HER2), but no association was seen for the triple negative breast tumor subtype. Our results add further evidence that a pro-inflammatory diet is associated with breast cancer risk with possible effect variation according to tumor subtype.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Francisco Félix Caballero ◽  
Ellen A. Struijk ◽  
Alberto Lana ◽  
Antonio Buño ◽  
Fernando Rodríguez-Artalejo ◽  
...  

AbstractElevated concentrations of acylcarnitines have been associated with higher risk of obesity, type 2 diabetes and cardiovascular disease. The aim of the present study was to assess the association between L-carnitine and acylcarnitine profiles, and 2-year risk of incident lower-extremity functional impairment (LEFI). This case–control study is nested in the Seniors-ENRICA cohort of community-dwelling older adults, which included 43 incident cases of LEFI and 86 age- and sex- matched controls. LEFI was assessed with the Short Physical Performance Battery. Plasma L-carnitine and 28 acylcarnitine species were measured. After adjusting for potential confounders, medium-chain acylcarnitines levels were associated with 2-year incidence of LEFI [odds ratio per 1-SD increase: 1.69; 95% confidence interval: 1.08, 2.64; p = 0.02]. Similar results were observed for long-chain acylcarnitines [odds ratio per 1-SD increase: 1.70; 95% confidence interval: 1.03, 2.80; p = 0.04]. Stratified analyses showed a stronger association between medium- and long-chain acylcarnitines and incidence of LEFI among those with body mass index and energy intake below the median value. In conclusion, higher plasma concentrations of medium- and long-chain acylcarnitines were associated with higher risk of LEFI. Given the role of these molecules on mitochondrial transport of fatty acids, our results suggest that bioenergetics dysbalance contributes to LEFI.


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