scholarly journals Effect of Repeated Exposure to Contrasting Temperatures on the Body of Working Age Men with Different Types of Autonomic Regulation

Author(s):  
Tat’yana A. Fisher ◽  
◽  
Svetlana S. Kolyvanova

The aim of this paper was to study changes in the haemodynamic and psychophysiological parameters of working age men as a result of repeated exposure to contrasting temperatures, depending on the type of autonomic regulation. Materials and methods. The research involved 14 men (aged 34.77 ± 5.66 years; office workers) divided into two groups according to Kérdö index: those with the sympathetic (n = 8) and parasympathetic (n = 6) types of self-regulation. Cold conditioning followed a certain plan of exposure to contrasting temperatures. The haemodynamic and psychophysiological parameters as well as adaptive potential were assessed 20 minutes before and 20 minutes after the exposure (alternating temperature cycles). We examined the following parameters: heart rate, systolic and diastolic blood pressure, pulse and mean arterial pressure, stroke volume, cardiac output, vascular resistance, and adaptive potential according to Baevsky. Integral psychophysiological parameters were determined using the Lüscher express method. Results. Subjects with predominance of sympathetic regulation both before and after the exposure to contrasting temperatures had higher values of heart rate and cardiac output and lower vascular resistance than the parasympathicotonic group. Individuals with predominance of parasympathetic regulation showed decreased cardiac output and a significant increase in vascular resistance after the exposure compared with the initial data. We found statistically significant differences in the integral parameters “heteronomy/autonomy” and “balance of personal traits” between the groups under study before the conditioning procedures. The research indicates that repeated exposure to contrasting temperatures not only affects the haemodynamic parameters, but also changes the psychophysiological parameters, motivated behaviour in particular. For citation: Fisher T.A., Kolyvanova S.S. Effect of Repeated Exposure to Contrasting Temperatures on the Body of Working Age Men with Different Types of Autonomic Regulation. Journal of Medical and Biological Research, 2021, vol. 9, no. 4, pp. 394–404. DOI: 10.37482/2687-1491-Z077

Author(s):  
A.M. Satarkulova

The assessment and dynamic control over students’ status is a very important task. It allows timely detection of prenosological status prior to pathology and health maintenance in students. The objective of the paper is to assess the adaptive abilities of the body, to analyze changes in heart rate variability indicators in students with various types of autonomic regulation, to identify prenosological status and precursory pathological symptoms. Materials and Methods. The study enrolled 302 students from India, aged 21.54±1.43. Programming complex «Psychophysiologist» was used to register the main HRV parameters within 5 minutes. Health status was evaluated according to the index of functional changes and the scale of functional states. Results. N.I. Shlyk (2009) distinguished two groups of students with different types of autonomic regulation: type 1 (53 %) with moderate and type 2 (5 %) with marked characteristics of central regulation profile, type 3 (35 %) with moderate and type 4 (7 %) with marked characteristics of autonomous regulation profile. Main parameters of HRV and adaptation potential were defined for each student.All the parameters characterized functional and health status. Conclusions. It was shown that 82 % of trial subjects (type 1), 53 % (type 2), 94 % (type 3) and 95 % (type 4) demonstrated satisfactory adaptation and their physiological processes were at an optimal level. 18 % of students (type 1) demonstrated reduced adaptive abilities of the body. Moreover, they were under moderate stress. 47 % of subjects (type 2) were also under a significant stress, which was proven by excessively high SI, low SDNN and TP, and an increased index of functional changes. 5 % of students (type 4) revealed dysfunctional characteristics in the heart rhythm, peculiar to pathology. Keywords: foreign students, heart rate variability, types of autonomic regulation, adaptation potential, functional status. Оценка состояния студентов и динамический контроль за ним является важной задачей, поскольку позволяет своевременно выявлять у студентов донозологические состояния, предшествующие патологии, и способствовать сохранению здоровья. Цель. Оценка адаптивных возможностей организма, анализ изменений показателей вариабельности сердечного ритма у студентов с различными типами вегетативной регуляции, выявление донозологических состояний и ранних признаков патологии. Материалы и методы. В исследовании участвовало 302 студента в возрасте 21,54+1,43 года из Индии. Регистрировались основные параметры ВСР в течение 5 мин с использованием программно-аппаратного комплекса «Психофизиолог». Состояние и уровень здоровья оценивались по индексу функциональных изменений и шкале функциональных состояний. Результаты. По способу, предложенному Н.И. Шлык, выделены группы студентов с различными типами вегетативной регуляции: I (53 %) и II типы (5 %) – с умеренным и выраженным преобладанием центрального контура регуляции соответственно, III (35 %) и IV типы (7 %) – с умеренным и выраженным преобладанием автономного контура регуляции соответственно. У каждого из студентов определены основные параметры ВСР и адаптационного потенциала, характеризующие функциональное состояние и уровень здоровья. Выводы. Показано, что для 82 % обследуемых с I типом, 53 % со II типом, 94 % c III типом и 95 % с IV типом регуляции характерно состояние удовлетворительной адаптации, физиологические процессы сохраняются на оптимальном уровне. В группе студентов I типа у 18 % студентов адаптивные возможности организма снижены, выявлено состояние умеренного напряжения. У 47 % обследуемых II типа также зафиксировано состояние резко выраженного напряжения, индикатором которого является чрезмерно высокое значение SI, низкие величины SDNN и ТP, повышенное значение индекса функциональных изменений. В группе студентов с IV типом у 5 % учащихсяв регуляции ритма сердца выявлены дисфункциональные признаки, характерные для патологии. Ключевые слова: иностранные студенты, вариабельность сердечного ритма, типы вегетативной регуляции, адаптационный потенциал, функциональное состояние.


1988 ◽  
Vol 66 (1) ◽  
pp. 29-39 ◽  
Author(s):  
P. J. Butler

When swimming at the surface with ready access to the air, aquatic birds and mammals appear to show the typical exercise response. There are increases in oxygen uptake, heart rate, and pulmonary ventilation. These are presumably accompanied by rises in cardiac output and perfusion to the active muscles, together with a reduction in overall peripheral vascular resistance. When restrained animals are submerged under water involuntarily, total oxygen consumption is reduced below the resting level as a result of a large reduction in perfusion of most parts of the body (including skeletal muscles) except the brain and heart. The underperfused parts metabolise anaerobically, producing lactic acid, while only the brain and heart consume oxygen. The large increase in peripheral vascular resistance is compensated by a proportionally similar reduction in cardiac output which results almost entirely from a reduction in heart rate below the resting level. This is the classical diving bradycardia. Evidence is presented from a number of aquatic birds and mammals that suggests that during the vast majority of natural dives metabolism is largely if not completely aerobic with the active skeletal muscles as well as the brain and heart receiving an adequate supply of oxygen. There may, however, be a reduced blood supply to other parts of the body including to the inactive skeletal muscles. Thus during most natural dives stored oxygen is used at an elevated rate, compared with resting, and is quickly replaced upon surfacing. It is possible for the animals to perform a number of such dives in fairly quick succession. In tufted ducks, at least, there seems to be a balance between the cardiovascular response to exercise and that to involuntary submersion with the bias towards the former. This balance can be shifted in the direction of the response to involuntary submersion when the birds swim long horizontal distances for their food (e.g., under ice in winter) or if they are briefly unable to surface (e.g., if rising vertically beneath ice).


Author(s):  
Gandhi M. ◽  
Swaminathan S.

Ghrelin as human natural hormones is involved in fundamental regulatory process of eating and energy balance. It is a stomach derived hormone that acts as at the ghrelin receptor in multiple tissues throughout to the body. Its properties includes increasing appetite, decreasing systemic inflammation, decreasing vascular resistance ,increasing cardiac output, increasing glucose and IGF-1 levels, Hence it may play a significant role in Diabetes mellitus. Many studies have linked ghrelin to obesity and this paper is an attempt to bring out recent findings on the role of ghrelin in Diabetes Mellitus, particularly type2 Diabetes mellitus.


Author(s):  
В. В. Кулик ◽  
В. Г. Бабийчук

В работе изучено влияние разных режимов ритмических экстремальных холодовых воздействий на состояние вегетативной регуляции сердечного ритма у молодых и старых крыс. По данным спектрального анализа вариабельности сердечного ритма установлено, что у молодых крыс использование температурных режимов ритмических экстремальных холодовых воздействий, РЭХВ (-120 °С; -120 °С; -120 °С) и (-60 °С; -120 °С; -120 °С) значительно повышало адаптационные возможности организма за счет активации собственных гомеостатических регуляторных систем. При этом комбинированный режим РЭХВ (-60 °С; -120 °С; -120 °С) оказался наиболее оптимальным для старых животных, поскольку его применение не сопровождалось чрезмерной активацией симпатико-адреналовой системы на ранних этапах экспериментальных исследований в отличие от режима (-120 °С; -120 °С; -120 °С). Кроме того, использование данного режима охлаждения способствовало статистически значимому увеличению показателей общей мощности спектра нейрогуморальной регуляции не столько за счет повышения активности гуморально-метаболического звена регуляции, преобладание которого характерно для пожилого возраста, сколько благодаря увеличению тонуса вегетативных центров, причем парасимпатические влияния на миокард превалировали над симпатическими. The influence of various rhythmic extreme cold effects on the state of autonomic regulation of heart rate in young and aged rats was studied. According to the spectral analysis of heart rate variability, it has been found that in young rats, using rhythmic extreme cold exposures (RECE) temperature regimens of (-120 °С; -120 °С; -120 °С) and (-60 °С; -120 °С; -120 °С) significantly increased adaptive capabilities of the body due to the activation of its own homeostatic regulatory systems. At the same time, the combined regimen of RECE (-60 °С; -120 °С; -120 °С) occurred to be the most optimal for aged animals, since its use was not accompanied with an excessive activation of sympathoadrenal system at the early stages of experimental studies, in contrast to the regimen (-120 °С; -120 °С; -120 °С). In addition, the use of this cooling mode contributed to a statistically significant increase in the total power of spectrum of neurohumoral regulation not so much due to a rise in activity of humoral-metabolic regulation link, the prevalence of which is characteristic of an old age, but due to an increase in the tone of vegetative centers, herewith the parasympathetic effects on the myocardium prevailed sympathetic ones.


1965 ◽  
Vol 209 (2) ◽  
pp. 397-403 ◽  
Author(s):  
Hermes A. Kontos ◽  
H. Page Mauck ◽  
David W. Richardson ◽  
John L. Patterson

The possibility that mechanisms secondary to the increased ventilation may contribute significantly to the circulatory responses to systemic hypoxia was explored in anesthetized dogs. In 14 spontaneously breathing dogs systemic hypoxia induced by breathing 7.5% oxygen in nitrogen increased cardiac output, heart rate, mean arterial blood pressure, and femoral arterial flow, and decreased systemic and hindlimb vascular resistances. In 14 dogs whose ventilation was kept constant by means of a respirator pump and intravenous decamethonium, systemic hypoxia did not change cardiac output, femoral arterial flow, or limb vascular resistance; it significantly decreased heart rate and significantly increased systemic vascular resistance. In seven spontaneously breathing dogs arterial blood pCO2 was maintained at the resting level during systemic hypoxia. The increase in heart rate was significantly less pronounced but the other circulatory findings were not different from those found during hypocapnic hypoxia. Thus, mechanisms secondary to increased ventilation contribute significantly to the circulatory responses to systemic hypoxia. Hypocapnia accounts partly for the increased heart rate, but not for the other circulatory responses.


1989 ◽  
Vol 256 (4) ◽  
pp. E536-E542 ◽  
Author(s):  
R. R. Magness ◽  
C. R. Rosenfeld

Systemic estradiol-17 beta (E2 beta) administration increases uterine blood flow (UBF), cardiac output (CO), heart rate (HR), and plasma renin activity (PRA). We sought to determine if the E2 beta-induced systemic responses were dependent on the observed uterine responses. Nonpregnant, ovariectomized ewes (n = 5) received 3 micrograms E2 beta into both uterine arteries followed 120 min later by systemic E2 beta, 1 microgram/kg. At 120 min after local E2 beta, UBF increased from 26 +/- 5 to 161 +/- 21 ml/min (P less than 0.05); uterine vascular resistance (UVR) decreased 83 +/- 2.5% (P less than 0.05); and systemic parameters were unchanged. At 120 min after systemic E2 beta, UBF remained elevated and CO had increased gradually from 4.4 +/- 0.2 to 5.5 +/- 0.32 l/min (26 +/- 3.4%, P less than 0.05), reflecting a 37 +/- 3.9% (P less than 0.05) increase in HR; mean arterial pressure (MAP) remained unchanged. The increased CO was associated with a 20 +/- 3.1% (P less than 0.05) fall in systemic vascular resistance (SVR), with % delta SVR less than % delta UVR (P less than 0.05). Base-line PRA and angiotensin II, 1.31 +/- 0.2 ng.ml-1.h-1 and 10.3 +/- 2.1 pg/ml, respectively, were unchanged by local E2 beta; systemic E2 beta caused increases to 3.56 +/- 0.51 ng.ml-1.h-1 (P less than 0.05) and 34.1 +/- 11.3 pg/ml (P less than 0.05), respectively. E2 beta-induced uterine hyperemia occurs independent of its systemic effects and is not responsible for systemic cardiovascular alterations, and the relative uterine vascular responses exceed systemic responses.(ABSTRACT TRUNCATED AT 250 WORDS)


1987 ◽  
Vol 253 (1) ◽  
pp. H126-H132
Author(s):  
R. W. Lee ◽  
L. D. Lancaster ◽  
D. Buckley ◽  
S. Goldman

To determine whether changes in the venous circulation were responsible for preload-afterload mismatch with angiotensin, we examined the changes in the heart and the peripheral circulation in six splenectomized dogs after ganglion blockade during an angiotensin infusion to increase mean aortic pressure 25 and then 50%. The peripheral circulation was evaluated by measuring mean circulatory filling pressure (MCFP), arterial compliance, and venous compliance. A 25% increase in mean aortic pressure increased MCFP from 6.2 +/- 0.3 to 7.6 +/- 0.3 mmHg (P less than 0.001) but did not change cardiac output, heart rate, or stroke volume. Systemic vascular resistance increased (P less than 0.01) from 0.50 +/- 0.02 to 0.59 +/- 0.03 mmHg X min X kg X ml-1. Arterial and venous compliances decreased (P less than 0.01) from 0.08 +/- 0.03 to 0.06 +/- 0.03 ml X mmHg-1 X kg-1 and from 2.1 +/- 0.1 to 1.6 +/- 0.1 ml X mmHg-1 X kg-1, respectively. A 50% elevation in mean aortic pressure increased MCFP from 7.1 +/- 0.4 to 9.5 +/- 0.9 mmHg (P less than 0.001) but did not change heart rate. At this level of aortic pressure, cardiac output and stroke volume decreased (P less than 0.01) 12 and 19%, respectively, whereas systemic vascular resistance increased (P less than 0.001) from 0.48 +/- 0.03 to 0.83 +/- 0.05 mmHg X min X kg X ml-1. Arterial and venous compliances decreased (P less than 0.01) from 0.08 +/- 0.01 to 0.05 +/- 0.01 ml X mmHg-1 X kg-1 and from 2.1 +/- 0.1 to 1.4 +/- 0.1 ml X mmHg-1 X kg-1, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)


2008 ◽  
Vol 108 (5) ◽  
pp. 802-811 ◽  
Author(s):  
Robert A. Dyer ◽  
Jenna L. Piercy ◽  
Anthony R. Reed ◽  
Carl J. Lombard ◽  
Leann K. Schoeman ◽  
...  

Background Hemodynamic responses to spinal anesthesia (SA) for cesarean delivery in patients with severe preeclampsia are poorly understood. This study used a beat-by-beat monitor of cardiac output (CO) to characterize the response to SA. The hypothesis was that CO would decrease from baseline values by less than 20%. Methods Fifteen patients with severe preeclampsia consented to an observational study. The monitor employed used pulse wave form analysis to estimate nominal stroke volume. Calibration was by lithium dilution. CO and systemic vascular resistance were derived from the measured stroke volume, heart rate, and mean arterial pressure. In addition, the hemodynamic effects of phenylephrine, the response to delivery and oxytocin, and hemodynamics during recovery from SA were recorded. Hemodynamic values were averaged for defined time intervals before, during, and after SA. Results Cardiac output remained stable from induction of SA until the time of request for analgesia. Mean arterial pressure and systemic vascular resistance decreased significantly from the time of adoption of the supine position until the end of surgery. After oxytocin administration, systemic vascular resistance decreased and heart rate and CO increased. Phenylephrine, 50 mug, increased mean arterial pressure to above target values and did not significantly change CO. At the time of recovery from SA, there were no clinically relevant changes from baseline hemodynamic values. Conclusions Spinal anesthesia in severe preeclampsia was associated with clinically insignificant changes in CO. Phenylephrine restored mean arterial pressure but did not increase maternal CO. Oxytocin caused transient marked hypotension, tachycardia, and increases in CO.


2021 ◽  
Vol 6 (4) ◽  
pp. 231-236
Author(s):  
Ulizko V. M. ◽  
◽  
V. R. Kryzhanivsky ◽  
T. M. Zakharkevich ◽  
I. L. Belyavsky

The condition of the cardiovascular system is one of the important criteria for assessing the impact of sports training on the human body. According to the indicators characterizing the state of the cardiovascular system, it is possible to trace the changes associated with fluctuations in the level of training, as well as to identify signs of overload as early as possible. The study of adaptive reactions of the cardiovascular system in athletes under physical activity is an important indicator for sports practice. The purpose of the study was to investigate the quantitative criteria for assessing the state of the cardiovascular system and approaches to correct the functional state of qualified athletes specializing in table tennis. Materials and methods. Studies of heart rate variability, quantitative and qualitative indicators that sufficiently reflect the autonomic functions of the body were used in order to assess the state of autonomic regulation in highly qualified athletes. Systematic physical activity causes a significant restructuring of the cardiovascular system and leads to morphofunctional changes in the mechanisms of the heart. Depending on the autonomic regulation of heart rhythm, there are different ways of myocardial adaptation processes. The balance of sympathetic and parasympathetic links of autonomic rhythm regulation is reflected in the activation of the left ventricle. Results and discussion. Adaptive changes of the cardiovascular system to competitive and training loads in the competitive period in qualified athletes are characterized by a significant decrease in heart rate (from 84.75±1.74 beats / min to 74.8±0.38 beats / min). In addition, a significantly faster process of restoring heart rate was established after exercise in the group of qualified athletes, compared with athletes of the category 1 at 4 (p >0.05) and 5 (p >0.05) minutes, respectively. According to the indicators of autonomic regulation of heart rhythm, activation of the parasympathetic link prevails in athletes of the category 1 in comparison with qualified athletes activation (according to high-frequency component, p <0.05). Significantly higher rates of individual parts of the body compared to low-skilled athletes were found out: the hormonal system (the indicator responsible for the hormonal part of the body – very low-frequency component) and the nervous system (indicators of the sympathetic nervous system – low frequency component). There are significantly higher values of the magnitude of the heart rate spectrum and high-frequency component at p <0.05, which indicates a higher power of all units of the parasympathetic regulation in the category 1 in relation to masters of sports and candidates masters of sports. Conclusion. Systematic physical activity causes a significant restructuring of the cardiovascular system and leads to morphofunctional changes in the mechanisms of the heart. Depending on the autonomic regulation of heart rhythm, there are different ways of myocardial adaptation processes. The balance of sympathetic and parasympathetic links of autonomic rhythm regulation is reflected in the activation of the left ventricle. The analysis showed that the spectral characteristics of heart rate variability significantly differ between groups of athletes with different dominance that are observed only in terms of high-frequency component, which in turn led to a change in the sympathetic-vagal balance


Author(s):  
VA Belyayeva

Background: One of the main negative factors of the educational environment is the increased stress impact on the cardiovascular system of students preparing for examinations. The cumulative effect of a long-term, systematic exposure to stressors may be accompanied by impaired mental and somatic health of students. The extent of response to stress is individual; it is usually determined by cardiovascular health and a complex of psychophysiological characteristics of the body. Objective: To study the main parameters of central hemodynamics in medical students depending on the body mass index and adaptive potential in the pre-examination study period Materials and methods: In spring–summer 2019, 170 medical students (young men and women aged 20.4 ± 0.3 years) with different adaptive potential of the circulatory system were surveyed during a pre-exam study period to establish their anthropometric indicators, blood pressure and heart rate and to further estimate the body mass index and the main central hemodynamics parameters. Results: The average heart rate of students during the pre-exam study period was 85.4 ± 12.21 beats per minute. The level of metabolic and energy processes in the myocardium was characterized as moderate with a tendency to insufficient functional capacity of the cardiovascular system (CI = 90.4 ± 1.22). Significant differences were revealed in a number of parameters un-der study depending on gender, body mass index (F = 3.99; p = 0.00890) and the adaptive potential of the circulatory system (F = 23.08; p = 0.00000). Conclusions: In the pre-examination study period, both the heart rate and the Kerdo index among the students were elevated, which indicates the predominance of sympathetic autonomic stress. The students with tense adaptation mechanisms demonstrated higher values of certain hemodynamic parameters. The pulse pressure and the Robinson index were higher in overweight students compared to their peers with a normal body mass index. None of the students with class 1 obesity had a satisfactory level of adaptation of the circulatory system. The analysis of central hemodynamic parameters enables the assessment of tolerance of the cardiovascular system of students to the burden of learning.


Sign in / Sign up

Export Citation Format

Share Document