Convalescent Plasma Therapy: An aspiring option for COVID-19 treatment?

2020 ◽  
Vol 4 (02) ◽  
pp. 52-56
Author(s):  
Akhil Ranjon Biswas ◽  
Md. Mahbubur Rahman
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Viral Infection ◽  
Neutralizing Antibodies ◽  
Therapeutic Option ◽  
Infected Person ◽  
Specific Therapy ◽  
Plasma Therapy ◽  
Corona Virus ◽  
The World ◽  
The City

COVID-19 is a cause of life threating severe acute respiratory syndrome (SARS) caused by a novel corona virus named as SARS-Cov-2. Since it has 1st been identified in the city of Wuhan in China in December, 2019, it has spread rapidly all over the world. As it is a newly emerged viral infection and any vaccine or specific therapy yet to be proven as clearly effective, multiple therapeutic option with supportive intent as well as search for specific therapy to combat the virus are under vigorous trial around the world. Convalescent plasma therapy is one such investigational therapeutic option for COVID-19 with hope that neutralizing antibodies present in plasma of persons recovered from COVID-19 would be able to neutralize the virus in infected person.

Coronavirus and Fingerprint Technology

2021 ◽  
Vol 13 (4) ◽  
pp. 1-16
Author(s):  
Gabriel B. Iwasokun
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Viral Infection ◽  
Virus Disease ◽  
High Rate ◽  
Corona Virus ◽  
The World ◽  
Almost All

The corona virus disease, otherwise known as COVID-19, is an extremely communicable and pathogenic viral infection caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), which emerged in Wuhan, China in December 2019 and has spread to almost all the countries in the world. The transmission of the virus is through touching of the nose, eyes, or mouth by a finger that has been contaminated through droplets on a surface when a carrier sneezes or coughs. Since the existing fingerprint devices are predominantly contact based, it implies that they can aid in the transmission of the virus. This paper discusses the application of fingerprint devices in notable places with high rate of COVID-19 infection as well as the threats to fingerprint technologies and the countermeasures. The need to change focus and orientation towards contactless biometric technologies as sure solution to the fear and animosity expressed towards contact-based fingerprint technology is also expatiated.

scholarly journals Literature Review of Epidemiological Phenomena: Corona Virus Disease Pandemic 2019

2020 ◽  
Vol 2 (3) ◽  
Author(s):  
Yarmaliza Yarmaliza ◽  
Teungku Nih Farisni ◽  
Fitriani Fitriani ◽  
Zakiyuddin Zakiyuddin ◽  
Fitrah Reynaldi ◽  
...  
Keyword(s):  
Virus Infection ◽  
Severe Acute Respiratory Syndrome ◽  
Literature Review ◽  
Virus Disease ◽  
Wuhan City ◽  
Corona Virus ◽  
The World ◽  
History Of ◽  
New Type ◽  
The City

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or Corona virus is a new type of coronavirus that is transmitted to humans. Corona virus infection called COVID-19 (Corona Virus Disease 2019) was first discovered in the city of Wuhan, China at the end of December 2019. Until March 2, 2020, more than 80 thousand confirmed cases have been reported in China. Of these cases, 49 thousand were identified in Wuhan City. Epidemiologically, the spread or distribution of this disease has a wide social and economic impact on the world. Many literature studies about the COVID-19 outbreak, such as causes, natural history of the disease, even to the preventive and medical treatment. Since the end of 2019 until April 2020, there have been many published literature or literature studies at both national and international levels, so this paper aims to examine literature studies related to COVID-19.

Plasma therapy a possible hope to fight against COVID-19

2020 ◽  
Author(s):  
Ravikant Piyush ◽  
Aroni Chatterjee ◽  
Shashikant Ray
Keyword(s):  
Middle East ◽  
Severe Acute Respiratory Syndrome ◽  
Viral Disease ◽  
Plasma Therapy ◽  
Therapeutic Drugs ◽  
Wild Fire ◽  
The World ◽  
Short Span ◽  
Game Changer

The world is currently going through a disastrous event and a catastrophic upheaval caused by the coronavirus disease 2019 (COVID-19). The pandemic has resulted in loss of more than 150000 deaths across the globe. Originating from China and spreading across all continents within a short span of time, it has become a matter of international emergency. Different agencies are adopting diverse approaches to stop and spread of this viral disease but still now nothing confirmatory has come up. Due to lack of vaccines and proper therapeutic drugs, the disease is still spreading like wild fire without control. An Old but very promising method- the convalescent plasma therapy could be the key therapy to stop this pandemic. This method has already proven its mettle on several occasions previously and has been found to be effective in curing the pandemics induced by Ebola, severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) belongs to the same group of β-Coronavirus that has resulted in the above diseases. Therefore, the role of plasma therapy is being explored for treatment of this disease. In this review, we have mainly focused on the role of convalescent plasma therapy and why its use should be promoted in fight against COVID-19, as it could turn out to be a game changer.

scholarly journals Coronavirus Pandemic: a major public health crisis for the developed and developing world

2021 ◽  
Vol 15 (03) ◽  
pp. 366-369
Author(s):  
Rooh Ullah ◽  
Muhammad Suleman Rana ◽  
Mehmood Qadir ◽  
Muhammad Usman ◽  
Niaz Ahmed
Keyword(s):  
Public Health ◽  
Severe Acute Respiratory Syndrome ◽  
Viral Infection ◽  
The Novel ◽  
Global Public Health ◽  
Health Crisis ◽  
Public Health Crisis ◽  
The World ◽  
Novel Coronavirus ◽  
Day By Day

Pandemic of novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infections in China is now become global public health crisis. At present 87.64% of the world is infected by this deadly illness. The risk from this epidemic depends on the nature of the virus, including how well it transmits from person to person, and the complications resulting from this current illness. The novel coronavirus has killed thousands of people in China and other countries as well; its rate of mortality is increasing day by day. There is an urgent need to control the virus by developing vaccine or any other antiviral drugs to save the world from this deadly viral infection.

scholarly journals The Emergence and Spread of Novel SARS-CoV-2 Variants

2021 ◽  
Vol 9 ◽  
Author(s):  
Huaimin Yi ◽  
Jin Wang ◽  
Jiong Wang ◽  
Yuying Lu ◽  
Yali Zhang ◽  
...  
Keyword(s):  
Immune Response ◽  
Severe Acute Respiratory Syndrome ◽  
Whole Genome Sequencing ◽  
Genome Sequencing ◽  
Neutralizing Antibodies ◽  
Whole Genome ◽  
Distribution Characteristics ◽  
S Protein ◽  
The World ◽  
Viral Genes

Since severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) began to spread in late 2019, laboratories around the world have widely used whole genome sequencing (WGS) to continuously monitor the changes in the viral genes and discovered multiple subtypes or branches evolved from SARS-CoV-2. Recently, several novel SARS-CoV-2 variants have been found to be more transmissible. They may affect the immune response caused by vaccines and natural infections and reduce the sensitivity to neutralizing antibodies. We analyze the distribution characteristics of prevalent SARS-CoV-2 variants and the frequency of mutant sites based on the data available from GISAID and PANGO by R 4.0.2 and ArcGIS 10.2. Our analysis suggests that B.1.1.7, B.1.351, and P.1 are more easily spreading than other variants, and the key mutations of S protein, including N501Y, E484K, and K417N/T, have high mutant frequencies, which may have become the main genotypes for the spread of SARS-CoV-2.

scholarly journals Effect of the Demographic of Covid-19 on Different Countries; Using the USA for Comparism

2021 ◽  
Vol 04 (02) ◽  
Author(s):  
Joseph Oyepata Simeon ◽  
Keyword(s):  
Immune Response ◽  
Severe Acute Respiratory Syndrome ◽  
United Nations ◽  
Close Contact ◽  
Herd Immunity ◽  
Infected Person ◽  
Robust Immune Response ◽  
The World ◽  
The Usa ◽  
The Many

Coronavirus disease 2019 (COVID-19) is a contagious disease caused by severe acute respiratory syndrome coronavirus. The virus that causes COVID-19 spreads mainly when an infected person is in close contact with another person. The aim of this study is to determine the effect of COVID-19 on different countries, using USA as comparism factor. Ninety four countries were selected based on their continents, countries and cases of infection. Data from each country were obtained from United Nations Geoscheme and WHO and were analyzed and compared to that of the United State of America (USA). Data analyzed revealed that most countries in Africa appears to be least affected by the virus. Data also revealed that many countries have been able to understand and manage the spread and infectivity of the virus compared to the USA. Result from the study also showed that the many countries have been able to improve on managing the infection when compared to USA mortality. This may be due to among other factors a more robust immune response, herd immunity and united approach in the management of the disease. The result also helps to provide insight as to how significant developing and providing vaccine may be to this part of the world. Result from the study suggests that while Africa has a better immunity for the virus, there seems to be improvement the management of disease by other continent.

scholarly journals Coronavirus respiratory illness in Saudi Arabia

2012 ◽  
Vol 6 (10) ◽  
pp. 692-694 ◽  
Author(s):  
Mohammed N. Al-Ahdal ◽  
Ahmed Ali Al-Qahtani ◽  
Salvatore Rubino
Keyword(s):  
Public Health ◽  
Saudi Arabia ◽  
Severe Acute Respiratory Syndrome ◽  
Viral Infection ◽  
Molecular Analysis ◽  
Respiratory Illness ◽  
Human Infection ◽  
Gulf Region ◽  
Health Authorities ◽  
The World

Although viruses that belong to the coronavirus family are known since the 1930s, they only gained public health attention when they were discovered to be the causative agent of the severe acute respiratory syndrome (SARS) outbreak in China in 2002–2003. On 22 September 2012, the Ministry of Health (MOH) in Saudi Arabia announced the detection of what was described as a “rare pattern” of coronavirus respiratory infection in three individuals, two Saudi citizens and one person from the Gulf Region. Neither Saudi citizen survived the infection. Molecular analysis of the isolates showed that the virus belongs to the genus beta-coronavirus. It is not known if the new isolates are circulating in the population or has recently diverged. The emergence of these novel isolates that resulted in fatal human infection ascertains that health authorities all over the world must be vigilant for the possibility of new global pandemics due to novel viral infection.

Role of Vitamins, Minerals and Herbs in Strengthening immune system against the newly Emerging Viral Disease SARS-CoV-2

2021 ◽  
pp. 309-315
Author(s):  
Ajay I. Patel ◽  
Pooja R. Maru ◽  
Ashok B. Patel ◽  
Amitkumar J. Vyas ◽  
Nilesh K. Patel
Keyword(s):  
Immune System ◽  
Severe Acute Respiratory Syndrome ◽  
Viral Infection ◽  
Viral Disease ◽  
The Body ◽  
Primary Stage ◽  
The Social ◽  
The World

The Coronavirus Disease 2019 (COVID-19) is caused by severe acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection Attack mainly on the immune system of the body. The current pandemic situation of COVID-19 has broken the social-economical Condition of the World. The Available Allopathic drug Paramedical system is attempting to manage the symptoms. But, there are no significant effects of the available drug system. So, it is better to move toward a supplement system that improves the body's immune system. Herbs, Minerals, and Vitamins can be boosting body immunity and prevent the respiratory Viral Disease SARS-CoV-2. It gives its response in the Primary Stage of COVID-19. So, it is better to towards the natural herbals, Minerals, and vitamins which can improve the immunity of the body and it can possibly prevent the viral infection.

scholarly journals Novel corona Virus (2019-nCoV) - An Ancient Ayurveda Epidemiology Literature Review.

2020 ◽  
Vol 8 (02) ◽  
Author(s):  
GANGAPRASAD ANANTRAO WAGHMARE
Keyword(s):  
Mortality Rate ◽  
Severe Acute Respiratory Syndrome ◽  
World Health Organization ◽  
Communicable Disease ◽  
World Health ◽  
Rate Estimate ◽  
Corona Virus ◽  
The World ◽  
Health Organization ◽  
Epidemic Diseases

 Coronaviruses (CoV) are a large family of viruses that cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV). In more severe cases, infection can cause pneumonia, severe acute respiratory syndrome, kidney failure and even death   Initially, the World Health Organization (WHO) had mentioned 2% as a mortality rate estimate in a press conference on Wednesday, January 29 and again on February 10. However, on January 29 2020 WHO specified that this was a very early and provisional estimate that might have changed. 3.4% Mortality Rate estimate by the World Health Organization (WHO) as of March 3 2020.                           The concept of epidemic was very much well defined in Ayurveda, Acharya Charaka the great physician of all ages had mentioned the epidemic diseases under the heading of “Janapadodhwans”.The aim of this review study is to understand the ancient Ayurveda epidemic literature , to prevent people from getting affected by epidemic diseases and to enlighten on epidemic diseases prevention & Management through Ayurveda. Keywords: Novel corona Virus (2019-nCoV),severe acute respiratory syndrome,Janapadodhwans,Ayurveda,epidemic Diseases,communicable disease,Panchakarma, Rasayan .  

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