Research progress in optical field regulation mechanism and optical devices based on non-Hermitian and topological effects (Invited)

2021 ◽  
Vol 50 (1) ◽  
pp. 20211001-20211001
Author(s):  
颜士玲 Shiling Yan ◽  
朱学艺 Xueyi Zhu ◽  
王洪飞 Hongfei Wang ◽  
解碧野 Biye Xie ◽  
张秀娟 Xiujuan Zhang ◽  
...  
2021 ◽  
Vol 50 (1) ◽  
pp. 20211001-20211001
Author(s):  
颜士玲 Shiling Yan ◽  
朱学艺 Xueyi Zhu ◽  
王洪飞 Hongfei Wang ◽  
解碧野 Biye Xie ◽  
张秀娟 Xiujuan Zhang ◽  
...  

2020 ◽  
Vol 47 (1) ◽  
pp. 0100002
Author(s):  
刘晓凤 Liu Xiaofeng ◽  
彭丽萍 Peng Liping ◽  
赵元安 Zhao Yuanan ◽  
王玺 Wang Xi ◽  
李大伟 Li Dawei ◽  
...  

Author(s):  
Xiaomin Wang ◽  
Ye Li ◽  
Li Han ◽  
Jie Li ◽  
Cun Liu ◽  
...  

Iron overload, a high risk factor for many diseases, is seen in almost all human chronic and common diseases. Iron chelating agents are often used for treatment but, at present, most of these have a narrow scope of application, obvious side effects, and other disadvantages. Recent studies have shown that flavonoids can affect iron status, reduce iron deposition, and inhibit the lipid peroxidation process caused by iron overload. Therefore, flavonoids with iron chelating and antioxidant activities may become potential complementary therapies. In this study, we not only reviewed the research progress of iron overload and the regulation mechanism of flavonoids, but also studied the structural basis and potential mechanism of their function. In addition, the advantages and disadvantages of flavonoids as plant iron chelating agents are discussed to provide a foundation for the prevention and treatment of iron homeostasis disorders using flavonoids.


2021 ◽  
Vol 5 (4) ◽  
pp. 1-7
Author(s):  
Zhuli Hou ◽  
Gang Fang

Abstract: The continuous increase in the incidence rate of various fatal malignant tumors in the recent years warrants an imperative search for medications or drugs with obvious anti-tumor effects and reliable curative effects. Previous studies have found that Curcuma zedoaria and its active ingredients, such as turmeric oil, curcumol, and ?-elemene, have obvious anti-tumor effects, and they do not have the adverse reactions and side effects seen in the anti-tumor drugs of Western medicine. Based on the review and inductive analysis of related literature, we summarize in the present article the results of some researchers who investigated the anti-tumor effects of Curcuma zedoaria and its active ingredients through the immune regulation mechanism.


Crystals ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 1015
Author(s):  
Kai Zuo ◽  
Yue Shi ◽  
Dan Luo

In the past two decades, polarization gratings (PGs) have attracted intensive attention due to the high-efficient diffraction and polarization selectivity properties. On one hand, the one-dimensional (1D) PGs have been investigated widely and adapted to various applications. On the other hand, optical signal manipulation stimulates the development of multibeam optical devices. Therefore, the development of two-dimensional (2D) PGs is in demand. This review summarizes the research progress of 2D PGs. Different designs and fabrication methods are summarized, including assembling two 1D polarization patterns, a 2D holographic lithography by polarization interference and a micro-pixelated electric field stimulated 2D liquid crystal (LC) structure. Both experiments and analyses are included. The design strategy, diffraction property, merits and demerits are discussed and summarized for the different methods.


2020 ◽  
Vol 21 (5) ◽  
pp. 1608 ◽  
Author(s):  
Shijie Zhang ◽  
Zongwen Li ◽  
Fei Xing

Graphene has received extensive scholarly attention for its extraordinary optical, electrical, and physicochemical properties, as well as its compatibility with silicon-based semiconductor processes. As a unique two-dimensional atomic crystal material, graphene has excellent mechanical properties, ultra-high carrier mobility, ultra-wide optical response spectrum, and strong polarization dependence effect, which make it have great potential in new optical and polarization devices. A series of new optical devices that are based on graphene have been developed, showing excellent performance and broad application prospects. In this paper, the recent research progress of polarizers, sensors, modulators, and detectors that are based on the polarization characteristics of graphene is reviewed. In particular, the polarization dependence effect and broadband absorption enhancement of graphene under total reflection structure are emphasized, which enhance the interaction between graphene and light and then provide a new direction for research of graphene polarization devices.


2021 ◽  
Vol 11 ◽  
Author(s):  
Na Fang ◽  
Guo-Wen Ding ◽  
Hao Ding ◽  
Juan Li ◽  
Chao Liu ◽  
...  

circular RNA (circRNA) is a closed ring structure formed by cyclic covalent bonds connecting the 5’-end and 3’-end of pre-mRNA. circRNA is widely distributed in eukaryotic cells. Recent studies have shown that circRNA is involved in the pathogenesis and development of multiple types of diseases, including tumors. circRNA is specifically expressed in tissues. And the stability of circRNA is higher than that of linear RNA, which can play biological roles through sponge adsorption of miRNA, interaction with RNA binding protein, regulation of gene transcription, the mRNA and protein translation brake, and translation of protein and peptides. These characteristics render circRNAs as biomarkers and therapeutic targets of tumors. Gastrointestinal tumors are common malignancies worldwide, which seriously threaten human health. In this review, we summarize the generation and biological characteristics of circRNA, molecular regulation mechanism and related effects of circRNA in gastrointestinal tumors.


2020 ◽  
Vol 3 (3) ◽  
pp. 36
Author(s):  
Saijia Li ◽  
Zhilu Li ◽  
Guanlu Li ◽  
Yiyu Cai ◽  
Yuxuan Wang ◽  
...  

As a fat-soluble vitamin, Vitamin D is a necessary hormone to maintain normal physiological activities of the body. In recent years, vitamin D has been considered as a new neuroendocrine-immunomodulatory hormone, and researchers have paid more attention to the study of immune regulatory mechanism. It is not only related to calcium and phosphorus metabolism, bone metabolism and other important metabolic mechanisms of the body, but also closely related to the immune regulation mechanism of the body. Vitamin D deficiency caused by many factors can play a certain role in the development of autoimmune diseases. In this paper, the related mechanisms of vitamin D affecting autoimmune diseases were reviewed, with a view to expound the close correlation between vitamin D and autoimmune diseases, so as to find new diagnosis and treatment approaches for clinical autoimmune diseases and improve the quality of life of patients with autoimmune diseases.


Author(s):  
Yuhao Zhang ◽  
Xiuchao Geng ◽  
Qiang Li ◽  
Jianglong Xu ◽  
Yanli Tan ◽  
...  

Abstract The chemical modification of RNA is a newly discovered epigenetic regulation mechanism in cells and plays a crucial role in a variety of biological processes. N6-methyladenine (m6A) mRNA modification is the most abundant form of posttranscriptional RNA modification in eukaryotes. Through the development of m6A RNA sequencing, the relevant molecular mechanism of m6A modification has gradually been revealed. It has been found that the effect of m6A modification on RNA metabolism involves processing, nuclear export, translation and even decay. As the most common malignant tumour of the central nervous system, gliomas (especially glioblastoma) have a very poor prognosis, and treatment efficacy is not ideal even with the application of high-intensity treatment measures of surgery combined with chemoradiotherapy. Exploring the origin and development mechanisms of tumour cells from the perspective of tumour biogenesis has always been a hotspot in the field of glioma research. Emerging evidence suggests that m6A modification can play a key role in gliomas through a variety of mechanisms, providing more possibilities for early diagnosis and targeted therapy of gliomas. The aim of the present review is to focus on the research progress regarding the association between m6A modification and gliomas. And to provide a theoretical basis according to the currently available literature for further exploring this association. This review may provide new insights for the molecular mechanism, early diagnosis, histologic grading, targeted therapy and prognostic evaluation of gliomas.


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