Epidemiology of Depression and Anxiety in Gout: A Systematic Review and Metaanalysis

2020 ◽  
Vol 48 (1) ◽  
pp. 129-137 ◽  
Author(s):  
Alyssa Howren ◽  
Drew Bowie ◽  
Hyon K. Choi ◽  
Sharan K. Rai ◽  
Mary A. De Vera
Keyword(s):  
Mental Health ◽  
Systematic Review ◽  
Search Strategy ◽  
Positive Association ◽  
Future Research ◽  
Depression And Anxiety ◽  
Inclusion Criteria ◽  
Random Effects Models ◽  
Cochrane Database ◽  
Epidemiology Of Depression

Objective.To conduct a systematic review of depression and anxiety among patients with gout that specifically evaluates the prevalence, incidence, determinants, and effects of these mental health comorbidities.Methods.We conducted a literature search in Medline, Embase, Cochrane Database of Systematic Reviews, CINAHL, and PsycINFO using indexed terms and key words to identify studies reporting on depression/anxiety in patients with gout. This review included full-text articles published in English that reported on patients with gout, evaluated depression/anxiety using a routinely reported measure, and provided estimates or sufficient data on the prevalence, incidence, determinants, or effects of depression/anxiety. Metaanalyses were conducted using random effects models.Results.Twenty of 901 articles identified through the search strategy met our inclusion criteria. All 20 studies evaluated depression, while only 10 assessed anxiety (50%). Metaanalyses suggest a positive association between mental health disorders and gout, as resultant pooled OR were 1.29 (95% CI 1.07–1.56) for depression and 1.29 (95% CI 0.96–1.73) for anxiety. Findings from four studies reporting on the incidence of depression in patients with gout resulted in a pooled HR of 1.17 (95% CI 1.01–1.36). Significant determinants of depression included number of tophi, frequency of flares, and oligo/polyarticular gout.Conclusion.Our systematic review suggests that depression and anxiety are significantly associated with gout, highlighting the need for future research to focus on the onset of mental disorders after gout diagnosis. We also identify potential targets for intervention.

A Systematic Review of Caregiver Burden following Stroke

2009 ◽  
Vol 4 (4) ◽  
pp. 285-292 ◽  
Author(s):  
H. Rigby ◽  
G. Gubitz ◽  
S. Phillips
Keyword(s):  
Mental Health ◽  
Social Support ◽  
Systematic Review ◽  
Caregiver Burden ◽  
Search Strategy ◽  
Patient Characteristics ◽  
Future Research ◽  
Reference Sections ◽  
Caregiver Mental Health ◽  
Significant Health

Caregiver burden following stroke is increasingly recognised as a significant health care concern. A growing number of studies have evaluated the patient, caregiver, and social support factors that contribute to increased caregiver burden. We conducted a systematic review of this literature to guide future research. A search of the MEDLINE, PsyclNFO, CINAHL, and EMBASE databases (up to July 2008) and reference sections of published studies using a structured search strategy yielded 24 relevant articles. Studies were included if they evaluated predictors and/or correlates of caregiver burden in the setting of stroke. The prevalence of caregiver burden was 25–54% and remained elevated for an indefinite period following stroke. In studies that evaluated independent baseline predictors of subsequent caregiver burden, none of the factors reported were consistent across studies. In studies that assessed concurrent factors independently contributing to caregiver burden in the poststroke period, patient characteristics and social support factors were inconsistently reported. Several studies identified caregiver mental health and the amount of time and effort required of the caregiver as significant determinants of caregiver burden. Our findings highlight the need for more research to identify caregivers in need of support and guide the development and implementation of appropriate interventions to offset caregiver burden.

scholarly journals The incidence of depression and anxiety in patients with ankylosing spondylitis: A systematic review and meta-analysis

2019 ◽  
Author(s):  
Jamie YE Park ◽  
Alyssa M Howren ◽  
Enav Z Zusman ◽  
John M Esdaile ◽  
Mary A De Vera
Keyword(s):  
Systematic Review ◽  
Ankylosing Spondylitis ◽  
Meta Analysis ◽  
Included Study ◽  
Depression And Anxiety ◽  
Random Effects Models ◽  
Cochrane Database ◽  
Increased Risk ◽  
Multivariable Regression ◽  
Psychiatric Complications

Abstract Background: As awareness for the importance of mental health continues to expand in rheumatology, it is important to understand the epidemiology of psychiatric complications in ankylosing spondylitis (AS) with the ultimate goal of future prevention and improved quality of care. This study aims to review evidence on the incidence and determinants of depression and/or anxiety among patients with AS. Methods: We searched Medline, Embase, Cochrane Database of Systematic Reviews, CINAHL Complete, and PsycINFO for full-length observational studies that involved a sample or population of patients with AS and assessed depression and/or anxiety. Primary outcomes extracted were: 1) risk estimates for depression and/or anxiety (e.g., relative risk [RR]); and 2) determinants or factors identified as independent predictors of depression and/or anxiety using multivariable regression approaches and corresponding estimates (e.g., odds ratios [OR]). Where relevant, we pooled estimates using random effects models. Results: Out of 783 titles from our search strategy, we reviewed 39 manuscripts. Four studies assessed the incidence of depression and meta-analyzing reported estimates from three of these studies yielded a pooled RR of 1.51 (95% CI 1.28 to 1.79). Differences in risk of depression among men and women with AS were inconclusive, suggesting need for further study. The incidence of anxiety was comparatively less studied with only one included study reporting a hazard ratio of 1.85 (95% CI 1.37 to 2.49). Education level was a key determinant, with lower levels associated with higher odds of depression (OR 6.65; 9% CI 1.36 to 32.51) and anxiety (OR 9.31; 9% CI 1.39 to 62.19) among AS patients. Conclusions: Our systematic review and meta-analysis shows an increased risk of depression and anxiety among patients with AS. These findings suggest the importance of monitoring and care for psychiatric conditions in AS.

scholarly journals COVID-19 and loneliness: A rapid systematic review

2021 ◽  
pp. 000486742110314
Author(s):  
Nagesh Pai ◽  
Shae-Leigh Vella
Keyword(s):  
Mental Health ◽  
Systematic Review ◽  
Adult Population ◽  
Future Research ◽  
Inclusion Criteria ◽  
Physical And Mental Health ◽  
Health And Wellbeing ◽  
General Adult Population ◽  
Key Terms ◽  
The Impact

Background: Loneliness is known to be associated with both poorer physical and mental health, being associated with increased mortality. Responses throughout the world to the current COVID-19 pandemic all incorporate varying degrees of social distancing and isolation. There is an imperative to provide a timely review and synthesis of the impact of COVID-19 on loneliness in the general population. Methods: PubMed was searched using the key terms ‘COVID-19’, ‘coronavirus’, ‘SARS-COV2’ and ‘loneliness’. Fifty-four articles were identified and screened against the inclusion criteria. The inclusion criteria stipulated that the study needed to incorporate a measure of loneliness with participants being drawn from the general adult population. Twenty-four studies met the inclusion criteria. Results: The key data extracted from the 24 reviewed studies are presented and summarised with a focus on key demographics of participants, the research designs utilised, the measures of loneliness employed and the other variables assessed in the studies. Overall, the findings indicate that loneliness has been a significant issue during the current COVID-19 pandemic and loneliness is positively associated with mental health symptoms. However, there were inconsistencies in the results evident across studies. Conclusion: To our knowledge, this is the first systematic review of research investigating loneliness during the current COVID-19 pandemic in the general adult population. Despite the inconsistencies evident in some of the results across the studies, it is clearly apparent that loneliness is having an impact on the mental health and wellbeing of the general adult population. Furthermore, it is apparent that the current COVID-19 pandemic has had an impact on loneliness in the general adult population and that loneliness is significantly positively associated with mental illness symptomatology. Thus, there is an imperative to address loneliness through public policy and interventions. The limitations of this review are noted and directions given for future research.

scholarly journals The incidence of depression and anxiety in patients with ankylosing spondylitis: A systematic review and meta-analysis

2020 ◽  
Author(s):  
Jamie YE Park ◽  
Alyssa M Howren ◽  
Enav Z Zusman ◽  
John M Esdaile ◽  
Mary A De Vera
Keyword(s):  
Systematic Review ◽  
Ankylosing Spondylitis ◽  
Meta Analysis ◽  
Included Study ◽  
Depression And Anxiety ◽  
Random Effects Models ◽  
Cochrane Database ◽  
Increased Risk ◽  
Multivariable Regression ◽  
Psychiatric Complications

Abstract Background: As awareness for the importance of mental health continues to expand in rheumatology, it is important to understand the epidemiology of psychiatric complications in ankylosing spondylitis (AS) with the ultimate goal of future prevention and improved quality of care. This study aims to review evidence on the incidence and determinants of depression and/or anxiety among patients with AS. Methods: We searched Medline, Embase, Cochrane Database of Systematic Reviews, CINAHL Complete, and PsycINFO for full-length observational studies that involved a sample or population of patients with AS and assessed depression and/or anxiety. Primary outcomes extracted were: 1) risk estimates for depression and/or anxiety (e.g., relative risk [RR]); and 2) determinants or factors identified as independent predictors of depression and/or anxiety using multivariable regression approaches and corresponding estimates (e.g., odds ratios [OR]). Where relevant, we pooled estimates using random effects models. Results: Out of 783 titles from our search strategy, we reviewed 39 manuscripts. Four studies assessed the incidence of depression and meta-analyzing reported estimates from three of these studies yielded a pooled RR of 1.51 (95% CI 1.28 to 1.79). Differences in risk of depression among men and women with AS were inconclusive, suggesting need for further study. The incidence of anxiety was comparatively less studied with only one included study reporting a hazard ratio of 1.85 (95% CI 1.37 to 2.49). Education level was a key determinant, with lower levels associated with higher odds of depression (OR 6.65; 9% CI 1.36 to 32.51) and anxiety (OR 9.31; 9% CI 1.39 to 62.19) among AS patients. Conclusions: Our systematic review and meta-analysis shows an increased risk of depression and anxiety among patients with AS. These findings suggest the importance of monitoring and care for psychiatric conditions in AS.

scholarly journals Social Media Use and Mental Health: A Global Analysis

Epidemiologia ◽  
2022 ◽  
Vol 3 (1) ◽  
pp. 11-25
Author(s):  
Osman Ulvi ◽  
Ajlina Karamehic-Muratovic ◽  
Mahdi Baghbanzadeh ◽  
Ateka Bashir ◽  
Jacob Smith ◽  
...  
Keyword(s):  
Mental Health ◽  
Systematic Review ◽  
Social Media ◽  
Global Analysis ◽  
Meta Analysis ◽  
Empirical Literature ◽  
Depression And Anxiety ◽  
Inclusion Criteria ◽  
Use Of Social Media ◽  
The Relationship

Research indicates that excessive use of social media can be related to depression and anxiety. This study conducted a systematic review of social media and mental health, focusing on Facebook, Twitter, and Instagram. Based on inclusion criteria from the systematic review, a meta-analysis was conducted to explore and summarize studies from the empirical literature on the relationship between social media and mental health. Using PRISMA guidelines on PubMed and Google Scholar, a literature search from January 2010 to June 2020 was conducted to identify studies addressing the relationship between social media sites and mental health. Of the 39 studies identified, 20 were included in the meta-analysis. Results indicate that while social media can create a sense of community for the user, excessive and increased use of social media, particularly among those who are vulnerable, is correlated with depression and other mental health disorders.

scholarly journals Social Networking Sites, Depression, and Anxiety: A Systematic Review

2016 ◽  
Vol 3 (4) ◽  
pp. e50 ◽  
Author(s):  
Elizabeth M Seabrook ◽  
Margaret L Kern ◽  
Nikki S Rickard
Keyword(s):  
Mental Health ◽  
Systematic Review ◽  
Mental Illness ◽  
Social Networking ◽  
Social Networking Sites ◽  
Well Being ◽  
Self Report ◽  
Future Research ◽  
Positive Interactions ◽  
Depression And Anxiety

Background Social networking sites (SNSs) have become a pervasive part of modern culture, which may also affect mental health. Objective The aim of this systematic review was to identify and summarize research examining depression and anxiety in the context of SNSs. It also aimed to identify studies that complement the assessment of mental illness with measures of well-being and examine moderators and mediators that add to the complexity of this environment. Methods A multidatabase search was performed. Papers published between January 2005 and June 2016 relevant to mental illness (depression and anxiety only) were extracted and reviewed. Results Positive interactions, social support, and social connectedness on SNSs were consistently related to lower levels of depression and anxiety, whereas negative interaction and social comparisons on SNSs were related to higher levels of depression and anxiety. SNS use related to less loneliness and greater self-esteem and life satisfaction. Findings were mixed for frequency of SNS use and number of SNS friends. Different patterns in the way individuals with depression and individuals with social anxiety engage with SNSs are beginning to emerge. Conclusions The systematic review revealed many mixed findings between depression, anxiety, and SNS use. Methodology has predominantly focused on self-report cross-sectional approaches; future research will benefit from leveraging real-time SNS data over time. The evidence suggests that SNS use correlates with mental illness and well-being; however, whether this effect is beneficial or detrimental depends at least partly on the quality of social factors in the SNS environment. Understanding these relationships will lead to better utilization of SNSs in their potential to positively influence mental health.

scholarly journals Tri-Response Police, Ambulance, Mental Health Crisis Models in Reducing Involuntary Detentions of Mentally Ill People: Protocol for a Systematic Review

2021 ◽  
Vol 18 (15) ◽  
pp. 8230
Author(s):  
Julia Heffernan ◽  
Ewan McDonald ◽  
Elizabeth Hughes ◽  
Richard Gray
Keyword(s):  
Mental Health ◽  
Systematic Review ◽  
Assessment Tool ◽  
Public Health Practice ◽  
Grey Literature ◽  
Risk Of Bias ◽  
Future Research ◽  
Mental Health Crisis ◽  
Health Crisis ◽  
Response Models

Police, ambulance and mental health tri-response services are a relatively new model of responding to people experiencing mental health crisis in the community, but limited evidence exists examining their efficacy. To date there have been no systematic reviews that have examined the association between the tri-response model and rates of involuntary detentions. A systematic review examining co-response models demonstrated possible reduction in involuntary detention, however, recommended further research. The aim of this protocol is to describe how we will systematically review the evidence base around the relationship of the police, ambulance mental health tri-response models in reducing involuntary detentions. We will search health, policing and grey literature databases and include clinical evaluations of any design. Risk of bias will be determined using the Effective Public Health Practice Project Quality Assessment Tool and a narrative synthesis will be undertaken to synthesis key themes. Risk of bias and extracted data will be summarized in tables and results synthesis tabulated to identify patterns within the included studies. The findings will inform future research into the effectiveness of tri-response police, ambulance, and mental health models in reducing involuntary detentions.

scholarly journals Stress and burnout in Improving Access to Psychological Therapies (IAPT) trainees: a systematic review

2021 ◽  
Vol 14 ◽  
Author(s):  
Joel Owen ◽  
Louise Crouch-Read ◽  
Matthew Smith ◽  
Paul Fisher
Keyword(s):  
Mental Health ◽  
Systematic Review ◽  
Mental Health Professionals ◽  
Health Professionals ◽  
Future Research ◽  
List Type ◽  
Dual Roles ◽  
Eligibility Criteria ◽  
Psychological Therapies ◽  
Current State

Abstract For more than a decade, Improving Access to Psychological Therapies (IAPT) has been training a new workforce of psychological therapists. Despite evidence of stress and burnout both in trainee mental health professionals, and qualified IAPT clinicians, little is known about these topics in IAPT trainees. Consequently, this systematic review sought to establish the current state of the literature regarding stress and burnout in IAPT trainees. Electronic databases were searched to identify all published and available unpublished work relating to the topic. On the basis of pre-established eligibility criteria, eight studies (including six unpublished doctoral theses) were identified and assessed for quality. This review identifies that research into the experience of IAPT trainees is under-developed. Existing evidence tentatively suggests that IAPT trainees may experience levels of stress and burnout that are higher than their qualified peers and among the higher end of healthcare professionals more generally. The experience of fulfilling dual roles as mental health professionals and university students concurrently appears to be a significant source of stress for IAPT trainees. More research regarding the levels and sources of stress and burnout in IAPT trainees is urgently needed to confirm and extend these findings. Recommendations for future research in the area are given. Key learning aims (1) To establish the current state of the literature regarding stress and burnout in IAPT trainees. (2) To raise practitioner, service and education-provider awareness regarding the levels and perceived sources of stress and burnout in IAPT trainees. (3) To make recommendations regarding future research on the topic.

Psychosocial Links Between Internet Use and Mental Health in Later Life: A Systematic Review of Quantitative and Qualitative Evidence

2015 ◽  
Vol 36 (12) ◽  
pp. 1471-1518 ◽  
Author(s):  
Anna K. Forsman ◽  
Johanna Nordmyr
Keyword(s):  
Mental Health ◽  
Systematic Review ◽  
Social Inclusion ◽  
Internet Use ◽  
Healthy Aging ◽  
Positive Association ◽  
Later Life ◽  
Individual Level ◽  
Information And Communication

Research on the role of information and communication technology (ICT) use for active aging is limited. The aim of this systematic review is to investigate the link between Internet use and mental health among older adults. The review was conducted based on searches in 9 electronic databases (2002-2014). A meta-synthesis approach was applied, examining quantitative (18) and qualitative (14) studies. The findings from the synthesis of quantitative statistical data indicate an overall positive association between Internet use and mental health and its psychosocial covariates in later life. The psychosocial links between Internet use and mental health identified from the qualitative data were (a) enhanced interpersonal interaction at individual level, (b) increased access to resources within the community, and (c) empowered social inclusion at society level. The results highlight the multi-level psychosocial links between Internet use and mental health, which may be applied in initiatives targeting healthy aging in various settings.

Explanatory Theories of Intimate Partner Homicide Perpetration: A Systematic Review

2020 ◽  
pp. 152483802095380
Author(s):  
Laurie M. Graham ◽  
Rebecca J. Macy ◽  
Cynthia F. Rizo ◽  
Sandra L. Martin
Keyword(s):  
Systematic Review ◽  
Ecological Model ◽  
Intimate Partner ◽  
Future Research ◽  
Intimate Partner Homicide ◽  
Inclusion Criteria ◽  
Search Terms ◽  
Social Ecological ◽  
Theoretical Perspectives ◽  
The Social

Theories play an important role in guiding intimate partner homicide (IPH) prevention research and practice. This study is the first systematic review of theories employed to explain why someone might kill their intimate partner. This review used rigorous methods to locate and synthesize literature that described explanatory theories of IPH perpetration. Using set search terms, we systematically searched 15 databases and repositories for theory-focused documents (i.e., theory papers or analyses) published in English from 2003 to 2018. Eighteen documents met these inclusion criteria and identified 22 individual theories that seek to explain why people might kill their intimate partners. These theories fell within four broader theoretical perspectives: feminist, evolutionary, sociological/criminological, and combined. Key tenets and focal populations of these 22 theories were identified and organized into a compendium of explanatory theories of IPH perpetration. Potential strengths and limitations of each of the four perspectives were described. Review findings underscored the likely importance of addressing gender as well as risk and protective factors at all levels of the social ecological model in efforts to understand IPH perpetration. The review findings highlighted the need for both integrated theories and a broader conceptual organizing framework to guide work aimed at IPH perpetration prevention to leverage the strengths of disparate theoretical perspectives. With the goal of informing future research, a preliminary iteration of such a framework is presented.

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