An Essay on the Political Economy Effects of the COVID-19 Pandemic as Twin Crises

2022 ◽  
pp. 1-18
Author(s):  
Irfan Kalaycı

The subject and purpose of this study is to examine the new type of coronavirus disease (COVID-19), which has turned into a global epidemic, with an economic-political approach. There are twin crises in the form of a health crisis (high human deaths) and an economic crisis (recession). Trillion-dollar aid packages from governments and international financial organizations also show that this global public health crisis has created an economic crisis. In the context of these crises, G-20 countries that did not intervene in their transmission channels in a timely manner showed the worst situations. This epidemic, calculated with the SIR model, is global, but the measures are local. What makes a clean, masked, and socially distant life obligatory against the risk of contamination is that this epidemic locks or restricts the whole economy, especially trade, education, and tourism. Measures called “new normalization” have started to relax in order to prevent further increase in unemployment and poverty.

2021 ◽  
pp. 092137402110143
Author(s):  
Nicholas De Genova

Like all ostensibly “natural” disasters, the COVID-19 coronavirus pandemic unceasingly reveals the depths of social inequality and political myopia or governmental recklessness that predictably exacerbate the effects of a more strictly natural calamity. The pandemic thereby exposes the grotesque disparities in how illness, death, and suffering are unevenly distributed. As the COVID-19 public health crisis has summarily provoked a global economic crisis, furthermore, it is simply unthinkable to comprehend the real ramifications of the pandemic outside of the sociopolitical relations of labor and capital, more generally. Furthermore, the global public health crisis commands that we reflect anew on the relations between human life and state power. Both for those who have historically and enduringly been subjected to expulsion from gainful employment, as for those whose labor-power is a commodity of choice for capital, exceedingly selected for hyper-exploitation, the coronavirus pandemic is a toxic matter of both class and race. These dire and increasingly desperate circumstances, however, reveal not only what is most barbaric about capitalist social relations but also the opportunity latent within this crisis.


2020 ◽  
pp. 230-234
Author(s):  
D. Hugh Whittaker ◽  
Timothy J. Sturgeon ◽  
Toshie Okita ◽  
Tianbiao Zhu

The onset of the Covid-19 pandemic has been traced to early December 2019, just as we were submitting our completed manuscript for publication. We were tempted to comb through the manuscript for ways to address what has rapidly emerged as an unprecedented global public health crisis, economic crisis, and more. But, we decided to leave the text be for several reasons. The first is the ongoing nature of the pandemic and its fallout. The scope of the damage and its long-term social, economic, and political effects will not be fully visible for years, and we are resistant to the business of prognostication. The second is that we believe the book, as it stands, can help make sense of some of the distinctive features of the pandemic, including its unprecedented speed of transmission to all corners of the globe and the economic chaos engendered by the disruption of industries embedded in the elaborate global supply chains and technology ecosystems that comprise GVCs. Third, it is very likely that the pandemic will intensify, if not actually cause, the overlapping and interacting crises that we depicted in ...


2019 ◽  
Vol 16 (11) ◽  
pp. 1202-1210 ◽  
Author(s):  
Michael Joseps Hearn ◽  
Gwendolyn Towers ◽  
Michael Henry Cynamon

Background:With approximately one-third of the world’s population infected, tuberculosis continues to be a global public health crisis. The rise of strains that are unusually virulent or highly resistant to current drugs is a cause of special concern, prompting research into new classes of compounds, as well as the re-evaluation of known chemotherapeutic agents.Objectives:The antimycobacterial activities associated with some recently-reported thiocarbonyl compounds kindled our interest in the synthesis of substituted hydrazinecarbothioamides (3) and carbonothioic dihydrazides (4), with the aim of investigating their potential in antitubercular drug design and discovery.Methods:In the present study, the title compounds 3 and 4 were prepared by the condensation of hydrazines with isothiocyanates in reactions readily controlled by stoichiometry, temperature and solvent. The compounds were assessed against Mycobacterium bovis BCG in Kirby-Bauer disc diffusion, and minimum inhibitory concentrations were determined against the virulent strain M. tuberculosis Erdman.Results:The chemical structures of these thermally stable compounds were determined by IR, 1HNMR, 13C-NMR, high-resolution mass spectrometry and elemental analysis. In the Kirby-Bauer disc diffusion assay, some of the compounds showed substantial diameters of inhibition against BCG. In some cases, the zones of inhibition were so large that no growth at all was observed on the assay plates. Against M. tuberculosis Erdman, several of the compounds showed significant activities. Compound 3h was the most active, demonstrating a minimum inhibitory concentration of 0.5 µg/mL.Conclusion:We found that the title compounds may be prepared conveniently in excellent purity and good yields. They are readily identified on the basis of their characteristic spectra. Some members of this class showed significant activities against mycobacteria. We conclude that further work will be warranted in exploring the antitubercular properties of these compounds.


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Yu Guo ◽  
Lisu Huang ◽  
Guangshun Zhang ◽  
Yanfeng Yao ◽  
He Zhou ◽  
...  

AbstractCOVID-19 pandemic caused by SARS-CoV-2 constitutes a global public health crisis with enormous economic consequences. Monoclonal antibodies against SARS-CoV-2 can provide an important treatment option to fight COVID-19, especially for the most vulnerable populations. In this work, potent antibodies binding to SARS-CoV-2 Spike protein were identified from COVID-19 convalescent patients. Among them, P4A1 interacts directly with and covers majority of the Receptor Binding Motif of the Spike Receptor-Binding Domain, shown by high-resolution complex structure analysis. We further demonstrate the binding and neutralizing activities of P4A1 against wild type and mutant Spike proteins or pseudoviruses. P4A1 was subsequently engineered to reduce the potential risk for Antibody-Dependent Enhancement of infection and to extend its half-life. The engineered antibody exhibits an optimized pharmacokinetic and safety profile, and it results in complete viral clearance in a rhesus monkey model of COVID-19 following a single injection. These data suggest its potential against SARS-CoV-2 related diseases.


Diseases ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 46
Author(s):  
Feng Xu ◽  
Yawei Wen ◽  
Xinge Hu ◽  
Tiannan Wang ◽  
Guoxun Chen

The newly found SARS-CoV-2 has led to the pandemic of COVID-19, which has caused respiratory distress syndrome and even death worldwide. This has become a global public health crisis. Unfortunately, elders and subjects with comorbidities have high mortality rates. One main feature of COVID-19 is the cytokine storm, which can cause damage in cells and tissues including the kidneys. Here, we reviewed the current literature on renal impairments in patients with COVID-19 and analyzed the possible etiology and mechanisms. In addition, we investigated the potential use of vitamin C for the prevention of renal injury in those patients. It appears that vitamin C could be helpful to improve the outcomes of patients with COVID-19. Lastly, we discussed the possible protective effects of vitamin C on renal functions in COVID-19 patients with existing kidney conditions.


2020 ◽  
pp. 1-11
Author(s):  
Pratik DIXIT

There is no time more opportune to review the workings of the International Health Regulations (IHR) than the present COVID-19 crisis. This article analyses the theoretical and practical aspects of international public health law (IPHL), particularly the IHR, to argue that it is woefully unprepared to protect human rights in times of a global public health crisis. To rectify this, the article argues that the IHR should design effective risk reduction and response strategies by incorporating concepts from international disaster law (IDL). Along similar lines, this article suggests that IDL also has a lot to learn from IPHL in terms of greater internationalisation and institutionalisation. Institutionalisation of IDL on par with IPHL will provide it with greater legitimacy, transparency and accountability. This article argues that greater cross-pollination of ideas between IDL and IPHL is necessary in order to make these disciplines more relevant for the future.


Author(s):  
Malose Makhubela ◽  
Solomon Mashegoane

Coronavirus disease 2019 (COVID-19) has spread widely leading to a global public health crisis of a pandemic proportion. Whilst infection rates tend to fluctuate in South Africa, COVID-19 remains a life-threatening disease with the capacity to wreak fear and concern. The present study evaluated the psychometric qualities of the Fear of COVID-19 Scale (FCV-19S) amongst black South African university students (N = 433; Female: 58%; Mage = 23.51 [SD = 4.18]). The FCV-19S demonstrated a unidimensional factor structure and acceptable internal consistency (α = 0.87), Omega (ω = 0.88) and the greatest lower bound (GLB = 0.90) reliabilities. In addition, discriminant validity was demonstrated when FCV-19S items loaded separately from ordinary fear. The FCV-19S can be used as a measure of COVID-19-related fear amongst black South African university students.


2021 ◽  
Vol 15 (03) ◽  
pp. 366-369
Author(s):  
Rooh Ullah ◽  
Muhammad Suleman Rana ◽  
Mehmood Qadir ◽  
Muhammad Usman ◽  
Niaz Ahmed

Pandemic of novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infections in China is now become global public health crisis. At present 87.64% of the world is infected by this deadly illness. The risk from this epidemic depends on the nature of the virus, including how well it transmits from person to person, and the complications resulting from this current illness. The novel coronavirus has killed thousands of people in China and other countries as well; its rate of mortality is increasing day by day. There is an urgent need to control the virus by developing vaccine or any other antiviral drugs to save the world from this deadly viral infection.


2020 ◽  
Author(s):  
Ayo Stephen Adebowale ◽  
Adeniyi Francis Fagbamigbe ◽  
Joshua Odunayo Akinyemi ◽  
Olalekan K Obisesan ◽  
Emmanuel J Awosanya ◽  
...  

Abstract Background: COVID-19 is an emerging global public health crisis. The increase in the daily COVID-19 confirmed cases in Nigeria is worrisome vis-a-vis its large and dense population. This study aims at assessing the first 120 days of COVID-19 case confirmation in Nigeria.Methods: Data extracted from the World Bank’s website were used for the descriptive assessment and modelling of COVID-19 disease using the first 120 days of the index case in Nigeria and seven other countries. Linear, quadratic, cubic and exponential methods of regression model were used to fit the data (α=0.05).Results: The COVID-19 growth pattern in Nigeria was similar to that of Egypt, Ghana and Cameroun; Nigeria COVID-19's daily death distribution was comparable to six of the other seven countries considered. There was an increasing trend in the daily COVID-19 confirmed cases in Nigeria. During the lockdown, the growth rate of COVID-19 in Nigeria was 5.85 (R2=0.728, p<0.001); however, it was 8.42 (R2=0.625, p<0.001) after the lockdown’s relaxation. Across all the countries investigated, the cubic polynomial model (CPM) provided the best fit for predicting COVID-19 cumulative cases and there was a clear deviation from the exponential growth model. Using the CPM, all things being equal, a 3-month (30 September 2020) prediction of COVID-19 cases in Nigeria was 155,467 (95% CI:151,111-159,824, p<0.001).Conclusions: An improvement in COVID-19 control measures and strict compliance with the COVID-19 recommended protocols are essential. A contingency plan is needed to provide care for the active cases in case the predicted target is realised.


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