Phytochemicals and Pharmacological Activities from Banana Fruits of Several Musa Species for Using as Cosmetic Raw Materials

2019 ◽  
Vol 891 ◽  
pp. 30-40 ◽  
Author(s):  
Chanai Noysang ◽  
Wiphupat Buranasukhon ◽  
Monsicha Khuanekkaphan
Keyword(s):  
Antioxidant Activity ◽  
Bioactive Compounds ◽  
Raw Materials ◽  
Ethanolic Extract ◽  
Inhibitory Effect ◽  
Musa Acuminata ◽  
Natural Source ◽  
Pharmacological Activities ◽  
Ethanolic Extracts ◽  
Reaction Test

The phytochemicals of the ethanolic extracts of unripe pulp and peel of banana fruits from several banana cultivars belonging to the Musa acuminata species (namely 'Kluai Namwa', 'Kluai Hom Thong', 'Kluai Leb Mu Nang', and 'Kluai Khai') were studied by color reaction test and HPTLC analysis. Kluai Khai pulp showed a highest amounts of ethanolic extractives (ca. 9.70±5.84% of dry material weight). The peel several banana showed similar qualitative phytochemicals. The major of phytochemicals identified in these extracts were alkaloids, flavonoids, tannins and polyphenols. The antioxidant activity was assessed using the 2,2-diphenyl-1-picrylhydrazyl assay. The analysed Kluai Hom Thong peel ethanolic extract showed a highest antioxidant activity at IC50 = 3.25±0.52 μg/ml and Kluai Hom Thong peel ethanolic extract showed a highest tyrosinase inhibitory effect at IC50 = 2.25±0.91 μg/ml. Kluai Hom Thong peel could be provide a potential natural source of bioactive compounds and could be beneficial to the cosmetic properties.

Evaluation of Phytochemicals and Pharmacological Activities of Ben-Cha-Lo-Ka-Wi-Chian Remedy

2019 ◽  
Vol 891 ◽  
pp. 52-59
Author(s):  
Chanai Noysang ◽  
Teerarat Pummarin
Keyword(s):  
Antioxidant Activity ◽  
Minimum Inhibitory Concentration ◽  
Inhibitory Concentration ◽  
Propionibacterium Acnes ◽  
Ethanolic Extract ◽  
Inhibition Zone ◽  
Inhibitory Effect ◽  
Pharmacological Activities ◽  
Ethanolic Extracts ◽  
Reaction Test

Benchalokawichian (BLW) remedy is a Thai traditional medicine that has been notified in the List of Medicine Products of the National List of Essential Drugs A.D. 2006 and has long been used as an antipyretic. The phytochemicals of the 70% and 95% ethanolic extracts of were studied by color reaction test and HPTLC analysis. The BLW remedy showed a highest amounts of 70% ethanolic extractives (ca. 3.99 ± 0.60% of dry material weight). The several ethanolic extracts showed similar qualitative phytochemicals. The major of phytochemicals identified in these extracts were alkaloids, flavonoids, tannins, and polyphenols. The antioxidant activity was assessed using the 2,2-diphenyl-1-picrylhydrazyl assay. The analysed 70% ethanolic extract showed a highest antioxidant activity at IC50= 526.09 µg/ml and both extracts not showed tyrosinase inhibitory effect. The 95% ethanolic extract showed the greatest anti-propionibacterium acnes activity with inhibition zone of 10.10 ± 0.45 mm and minimum inhibitory concentration (MIC) was 5.05 mg/ml

Preliminary Phytochemicals and Pharmacologic Activities Assessment of White and Pink Nelumbo nucifera Gaertn. Flowers

2019 ◽  
Vol 891 ◽  
pp. 41-51
Author(s):  
Chanai Noysang ◽  
Nutsuda Boonmatit
Keyword(s):  
Antioxidant Activity ◽  
Ethanolic Extract ◽  
Inhibitory Effect ◽  
White Flower ◽  
Nelumbo Nucifera ◽  
Color Reaction ◽  
Natural Source ◽  
Pink Flower ◽  
Ethanolic Extracts ◽  
Reaction Test

The phytochemicals of the ethanolic extracts of petals and stamens of lotus flowers from several lotus cultivars belonging to the Nelumbo nucifera Gaertn. (namely 'lotus white flower' and 'lotus pink flower') were studied by color reaction test and HPTLC analysis. The lotus pink flower stamens showed a highest amount of ethanolic extractives (ca. 18.33±2.14% of dry material weight). The several the ethanolic extracts of N. nucifera petals and stamens showed similar qualitative phytochemicals. The crude extracts revealed the presence of flavonoids, terpenoinds, tannins and polyphenols. The antioxidant activity was assessed using the 2,2-diphenyl-1-picrylhydrazyl assay. The analyzed lotus pink flower stamens ethanolic extract showed a highest antioxidant activity at IC50 = 0.61±0.16 μg/ml and lotus pink flower petals ethanolic extract showed a highest tyrosinase inhibitory effect at IC50 = 2.25±0.21 μg/ml. N. nucifera flowers could be provide a potential natural source of phytochemicals and could be beneficial to the cosmetic properties.

Upcycling Culinary Organic Waste: Production of Plant Particles from Potato and Carrot Peels to Improve Antioxidative Capacity

2020 ◽  
Vol 01 ◽  
Author(s):  
Dalia A. Yassin ◽  
Muhammad Jawad Nasim ◽  
Abraham M. Abraham ◽  
Cornelia M. Keck ◽  
Claus Jacob
Keyword(s):  
Antioxidant Activity ◽  
High Speed ◽  
Antioxidant Activities ◽  
Raw Materials ◽  
Ethanolic Extract ◽  
Correlation Spectroscopy ◽  
Waste Production ◽  
Biological Potential ◽  
Ethanolic Extracts ◽  
Vegetables And Fruits

Background: Vegetables and fruits are consumed in considerable amounts worldwide producing huge quantities of organic leftovers comprising primarily of peels. Peels of potatoes (PP) and carrots (CP), for instance, are often considered as waste, albeit they still represent a rich source of interesting phytochemicals. Traditional waste management of such materials, usually vermicomposting, therefore represents a low value approach and also a considerable burden to the environment. Objective: Aiming to turn some of this waste into raw materials for further applications, methods were explored to prepare suspensions of PP and CP. Antioxidant activities of these suspensions were compared to bulk-suspensions and the corresponding ethanolic extracts in anticipation of possible applications in Nutrition and Cosmetics. Methods: The peels of potatoes and carrots were subjected to high speed stirring (HSS) and high pressure homogenization (HPH) to produce the suspensions which were characterized for size distribution by Laser Diffraction (LD), Photon Correlation Spectroscopy (PCS) and light microscopy (LM). The ethanolic extracts of peels were also produced. All of the samples were evaluated for antioxidant activity employing 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. Results: HPH produced suspensions of peels comprised of particles with diameters in the range of 268 - 335 nm for PP and 654 - 1,560 nm for CP. These suspensions exhibited a significantly stronger antioxidant activity compared to the bulk-suspensions. Moreover, the suspension of PP (1% w/w) exhibited comparable antioxidant activity to the ethanolic extract (1% w/w) whilst the CP suspension (1% w/w) exhibited lower activity compared to the ethanolic extract. Conclusion: Production of suspensions of vegetable peels may unlock some biological potential which could be optimised for applications in Nutrition, Agriculture, Medicine and Cosmetics.

scholarly journals Prunus persica var. platycarpa (Tabacchiera Peach): Bioactive Compounds and Antioxidant Activity of Pulp, Peel and Seed Ethanolic Extracts

2015 ◽  
Vol 70 (3) ◽  
pp. 331-337 ◽  
Author(s):  
Monica R. Loizzo ◽  
Deborah Pacetti ◽  
Paolo Lucci ◽  
Oscar Núñez ◽  
Francesco Menichini ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Bioactive Compounds ◽  
Prunus Persica ◽  
Ethanolic Extracts

scholarly journals Chemical Fingerprint Analysis of Phenolics of Albizia chinensis Based on Ultra-Performance LC-Electrospray Ionization-Quadrupole Time-of-Flight Mass Spectrometry and Antioxidant Activity

2011 ◽  
Vol 6 (11) ◽  
pp. 1934578X1100601 ◽  
Author(s):  
Abha Chaudhary ◽  
Pushpinder Kaur ◽  
Neeraj Kumar ◽  
Bikram Singh ◽  
Shiv Awasthi ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Antioxidant Activity ◽  
Electrospray Ionization ◽  
Time Of Flight ◽  
Ethanolic Extract ◽  
Ultra Performance Liquid Chromatography ◽  
Reversed Phase ◽  
Flight Mass Spectrometry ◽  
Ethanolic Extracts ◽  
C Nmr

Albizia species have been shown to have anti-inflammatory and antiallergic properties. However, efficient analytical methods for identification of their active constituents are still lacking. Ultra-performance liquid chromatography coupled with electrospray ionization-quadrupole time-of-flight mass spectrometry (UPLC-ESI-QTOF-MS) was used to study the phenolic composition of the ethanolic extracts of different parts (flowers, leaves, pods and bark) of A. chinensis. In addition, the antioxidant activity of the ethanolic extracts was evaluated by the 1,1-diphenyl-2-picryl hydrazyl (DPPH) free-radical and 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid (ABTS) radical cation scavenging methods. Four compounds were isolated from the ethanolic extract of the flowers and characterized by 1H and 13C NMR spectroscopy as quercetin-3- O-rhamnoside, quercetin, quercetin-3- O-arabinofuranoside, and myricetin-3- O-rhamnoside. Separation and quantification of the phenolics was accomplished using a reversed-phase BEH C18 column with the mobile phase of methanol–water (0.05% formic acid), and detection wavelengths of 360 and 254 nm.

scholarly journals GC–MS study on ethanolic extract of Vetiveria lawsonii root

2016 ◽  
Vol 5 (3) ◽  
pp. 108-111
Author(s):  
P Ramachandran ◽  
◽  
Viji Saral Elezabeth D Elezabeth D ◽  
Keyword(s):  
Mass Spectrometer ◽  
Bioactive Compounds ◽  
Ethanolic Extract ◽  
Pharmacological Activities ◽  
Ms Analysis

The present study was focused to scrutinize the presence of phytoconstituents in the ethanolic extract of Vetiveria lawsonii root using GC-MS. The GC-MS analysis of Vetiveria lawsonii root was performed using Agilent 6890-JEOL GC-Mate-II Mass Spectrometer. The result of the study showed the presence of six bioactive compounds in the ethanolic extract. On account of this investigation, we can conclude that the ethanolic extract of Vetiveria lawsonii root shows the presence of 6 bioactive phytoconstituents. This might be the cause for the various pharmacological activities of the plant.

scholarly journals Anti-Melanogenic Effect of Ethanolic Extract of Sorghum bicolor on IBMX–Induced Melanogenesis in B16/F10 Melanoma Cells

Nutrients ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 832 ◽  
Author(s):  
Hye Ju Han ◽  
Seon Kyeong Park ◽  
Jin Yong Kang ◽  
Jong Min Kim ◽  
Seul Ki Yoo ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Sorghum Bicolor ◽  
Antioxidant Activities ◽  
Radical Scavenging ◽  
Ethanolic Extract ◽  
Ethanol Extract ◽  
Inhibitory Effect ◽  
Melanoma Cells ◽  
Total Phenolic ◽  
Skin Whitening

To evaluate possibility as a skin whitening agent of Sorghum bicolor (S. bicolor), its antioxidant activity and anti-melanogenic effect on 3-isobutyl-1-methylxanthine (IBMX)-induced melanogenesis in B16/F10 melanoma cells were investigated. The result of total phenolic contents (TPC) indicated that 60% ethanol extract of S. bicolor (ESB) has the highest contents than other ethanol extracts. Antioxidant activity was evaluated using the 2,2’-azino-bis-(3-ethylbenzothiazolin-6-sulfonic acid) diammonium salt (ABTS)/1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging activities and malondialdehyde (MDA) inhibitory effect. These results showed ESB has significant antioxidant activities. Inhibitory effect against tyrosinase was also assessed using L-tyrosine (IC50 value = 89.25 μg/mL) and 3,4-dihydroxy-L-phenylalanine (L-DOPA) as substrates. In addition, ESB treatment effectively inhibited melanin production in IBMX-induced B16/F10 melanoma cells. To confirm the mechanism on anti-melanogenic effect of ESB, we examined melanogenesis-related proteins. ESB downregulated melanogenesis by decreasing expression of microphthalmia-associated transcription factor (MITF), tyrosinase and tyrosinase-related protein (TRP)-1. Finally, 9-hydroxyoctadecadienoic acid (9-HODE), 1,3-O-dicaffeoylglycerol and tricin as the main compounds of ESB were analyzed using the ultra-performance liquid chromatography-ion mobility separation-quadrupole time of flight/tandem mass spectrometry (UPLC-IMS-QTOF/MS2). These findings suggest that ESB may have physiological potential to be used skin whitening material.

scholarly journals GC-MS Analysis of Bioactive Compounds and Phytochemical Evaluation of the Ethanolic Extract of Gomphrena globosa L. Flowers

2020 ◽  
Vol 10 (2) ◽  
pp. 53-58
Author(s):  
Azmat Unnisa Esmat ◽  
Sirisha Mittapally ◽  
Safiya Begum
Keyword(s):  
Bioactive Compounds ◽  
Ethanolic Extract ◽  
Pharmacological Activities ◽  
Ms Analysis ◽  
Gomphrena Globosa ◽  
Whole Plant ◽  
Docosanoic Acid ◽  
Phytochemical Compounds ◽  
Phytochemical Constituents ◽  
Anti Inflammatory

Gomphrena globosa (L.) has high medicinal values. All parts are been used as folk medicines. The extract of whole plant / flowers has shown different phytochemical constituents with various clinical properties. These phytochemicals recognised are responsible for various activities such as anti-inflammatory, anticancer, antibacterial, analgesic and cytotoxic. The ethanolic extract of Gomphrena globosa L. flowers of biochemical test indicates the presence of sterols, triterpenoid, tannins, phenols and flavonoids, and on GC-MS analysis it has shown 11 phytochemical compounds with different pharmacological activities. The major bioactive compounds are Docosanoic Acid, Docosyl Ester (25.404%) and Hexatriacontane (24.324%), has proven anti-inflammatory activity. Keywords: Gomphrena globose L., phytochemical constituents, GC-MS and anti-inflammatory.

scholarly journals Antioxidant Activity and Cytotoxicity of Taraxacum Hispanicum Aqueous and Ethanolic Extracts on Hepg2 Cells

2017 ◽  
Vol 9 (1) ◽  
Author(s):  
Gupta Meenu ◽  
Nogueira A ◽  
Almeida R ◽  
Oliveira A. I. ◽  
Oliveira R. F. ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Cell Viability ◽  
Hepg2 Cell ◽  
Aqueous Extract ◽  
Antioxidant Properties ◽  
Ethanolic Extract ◽  
In Vitro Test ◽  
Dependent Manner ◽  
Chelating Activity ◽  
Ethanolic Extracts

Introduction: Plants belonging to the genus Taraxacum have been used in traditional medicine. Nowadays, extracts of these plants have been reported for the treatment of diseases, including liver disorders. Increasing interest and research on these plants also revealed its potential for treating cancer. This study aims to evaluate the antioxidant activity and cytotoxic properties of crude extracts from aerial parts of Taraxacum hispanicum H.Lindb, against human hepatocarcinoma (HepG2). Material and methods: Evaluation of the antioxidant properties was performed using DPPH in vitro test, superoxide scavenging assay and Fe2+ chelating activity. MTT assay was used to determine metabolic activity, for 24 and 48 hours. Results: For antioxidant capacity of the ethanolic extract (overall the one with the best results), IC50 values were 62.4 ± 6.7 μg/ml (DPPH radical scavenging activity) 53.9 ± 10.3 μg/ml (Fe2+ chelating activity) and 2.0 ± 0.3 μg/ml (superoxide scavenging assay). The aqueous and ethanolic extracts had different effects on HepG2 cell viability. Aqueous extract induced cell cytotoxicity in a time and dose-dependent manner, leaving only 52.6% viable cells at a concentration of 200 μg/ml, after 48 h. An increase in the cell viability was seen in the ethanolic extract, from 24 h to 48 h at higher concentrations. Conclusions: Ethanolic extract of T. hispanicum was the most promising, presenting anti-oxidative capacity and only the aqueous extract of the plant presented more relevant cytotoxicity over HepG2 cell line. These activities may be related with the extract phenolic content. However, further studies are needed to elucidate the main mechanisms responsible for these potential effects.

scholarly journals The The Phytochemical Screening, Total Phenolic Contents and Antioxidant Activities in Vitro of White Oyster Mushroom (Pleurotus Ostreatus) Preparations

2019 ◽  
Vol 7 (15) ◽  
pp. 2404-2412
Author(s):  
Santun Bhekti Rahimah ◽  
Dhiah Dianawaty Djunaedi ◽  
Arto Yuwono Soeroto ◽  
Tatang Bisri
Keyword(s):  
Antioxidant Activity ◽  
Pleurotus Ostreatus ◽  
Antioxidant Activities ◽  
Ethanolic Extract ◽  
Total Phenolic ◽  
Phytochemical Analysis ◽  
Phytochemical Screening ◽  
Ethanolic Extracts ◽  
Active Substances

BACKGROUND: The popular commercially cultivated Pleurotus ostreatus mushroom contains very high nutrients and bioactive compounds with high antioxidant activity. The ethanolic extract seems to be the most active in preparation. AIM: This study has an aim to compare the phytochemical analysis of a fresh, dry and ethanolic extract of Pleurotus ostreatus, to measure the total phenolic content and antioxidant activities in vitro of ethanolic extracts of Pleurotus ostreatus. METHODS: The fresh plant's materials (FPM), dry plants materials (DPM), ethanolic extracts were macerated with 70% (EE70) and 96% ethanol (EE96) of Pleurotus ostreatus which were used for phytochemical analysis, and EE96 was used for antioxidant activity in vitro. The phytochemical analysis was conducted using the Dragendorf and Meyer, FeCl3 test, Salkowsky method, Lieberman method, amyl alcohol, foam test and the NaOH reagent. The total phenol test was carried out using the Follin-Ciocalteu method. The antioxidant activity was tested using the ABTS and H2O2 essay. RESULTS: The phytochemical screening showed that the flavonoid, phenolic compounds, tannin, saponin, alkaloids, and steroids were detected in the FPM, DPM, EE70 and also the EE96. The alkaloid, however, was not identified by the Meyer Reagent in the FPM and DPM. The DPM and EE70 seemed to have the highest amount of saponin based on the foam that was formed. Meanwhile, steroids and flavonoids were detected at a higher level in the EE96, based on the strength of visible colour. However, triterpenoid and quinones could not be identified. In the total phenol test, there was an amount of 6.67 μg phenol in a 1 mg extract sample which was equivalent to 1 mg of Gallic Acid. The EE96 has an IC50 of 108.07 μg/mL for ABTS and an IC50 reduction of 229.17 μg/mL. The process of Pleurotus ostreatus drying did not reduce the content of active substances. The polar active substances seem to be more soluble in the EE70 than the EE96. CONCLUSION: The higher the bioactive substances in the preparation, the more significant the bio-therapeutic effects. Ethanolic extract of Pleurotus ostreatus has a phenol content and a good antioxidant action.  

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