Preparation of Chitosan-Thiamine Pyrophosphate/Polyvinyl Alcohol Blend Electrospun Nanofibers

2012 ◽  
Vol 506 ◽  
pp. 118-121 ◽  
Author(s):  
Natthan Charernsriwilaiwat ◽  
Theerasak Rojanarata ◽  
Tanasait Ngawhirunpat ◽  
Praneet Opanasopit
Keyword(s):  
Polyvinyl Alcohol ◽  
Electrospun Fiber ◽  
Weight Ratio ◽  
Electrospun Nanofibers ◽  
Average Diameter ◽  
Thiamine Pyrophosphate ◽  
Scanning Calorimetry ◽  
Fiber Mats ◽  
Transdermal Drug Delivery Systems ◽  
Nanofiber Mats

Electrospinning of chitosan (CS) has been interested due to the excellent properties of CS such as biocompatibility, biodegradability, antibacterial and non toxic. In this study, chitosan-thiamine pyrophosphate (CS-TPP)/polyvinyl alcohol (PVA) blend nanofibers were prepared using electrospinning techniques without acidic and organic solvent. CS was dissolved with TPP aqueous solution and then blended with PVA solution at various weight ratios. Physicochemical properties of CS-TPP/PVA solution such as viscosity, conductivity and surface tension were evaluated. The morphology and diameter of the electrospun fiber mats were investigated by using scanning electron microscopy (SEM). The chemical structure was characterized by Fourier Transform Infrared (FT-IR) spectroscopy and Differential Scanning Calorimetry (DSC). The morphology and diameter of the nanofibers were mainly affected by the weight ratio of the blend polymers. Nanofibers were obtained when the CS-TPP content was less than 50 % wt. The average diameter of the nanofibers was 99.91-216.42 nm, and the fiber diameter decreased with increasing CS-TPP content. Cytotoxicity tests in human fibroblast cells showed that the fibers had low toxic to the cells. In conclusion, these CS electrospun nanofiber mats can be applied for the wound dressing or transdermal drug delivery systems.

Fabrication and Characterization of Chitosan-Ethylenediaminetetraacetic Acid/Polyvinyl Alcohol Blend Electrospun Nanofibers

2011 ◽  
Vol 194-196 ◽  
pp. 648-651 ◽  
Author(s):  
Natthan Charernsriwilaiwat ◽  
Praneet Opanasopit ◽  
Theerasak Rojanarata ◽  
Tanasait Ngawhirunpat
Keyword(s):  
Polyvinyl Alcohol ◽  
Ethylenediaminetetraacetic Acid ◽  
Electrospun Fiber ◽  
High Surface ◽  
Weight Ratio ◽  
Average Diameter ◽  
High Porosity ◽  
Sem Images ◽  
Fiber Mats ◽  
Small Pore

Electrospinning is a technique use to fabricate ultrafine fibers with diameters in the nanometer range. The electrospun fiber mats have high potentials for many applications, due to their high surface area to volume, high porosity and small pore size. In this study, chitosan-ethylenediaminetetraacetic acid (CS-EDTA)/polyvinyl alcohol (PVA) blend nanofibers were successfully prepared using electrospinning techniques without organic solvent. CS was dissolved in EDTA aqueous solution and then blended with PVA solution at various weight ratios. Physicochemical properties of CS-EDTA/PVA solution such as viscosity, conductivity and surface tension were investigated. The morphology and diameter of the electrospun fiber mats were analyzed by using scanning electron microscopy (SEM). The composite structure was characterized by differential scanning calorimetry (DSC) and fourier transform infrared spectroscopy (FT-IR). SEM images showed that the morphology and diameter of the nanofibers were mainly affected by the weight ratio of the blend. Nanofibers were obtained when the CS-EDTA content was less than 50%wt. The average diameter of the nanofibers was 119-223 nm, and this average diameter decreased with increasing CS-EDTA content. In summary, these CS electrospun nanofiber mats may be proper for the drug delivery or wound dressing application.

Electrospun Nanofibers Based on Polyvinyl Alcohol/Chitosan and its Stability in KOH Solution

2015 ◽  
Vol 827 ◽  
pp. 321-325 ◽  
Author(s):  
Kuwat Triyana ◽  
M. Solihul Mu’min ◽  
Kuni Faizah ◽  
Yusril Yusuf ◽  
Ahmad Kusumaatmaja ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Fuel Cells ◽  
Polyvinyl Alcohol ◽  
Electrolyte Solution ◽  
Weight Ratio ◽  
Electrospun Nanofibers ◽  
Average Diameter ◽  
Stability Testing ◽  
Electrolyte Membrane ◽  
Chitosan Concentration

Fabrication of nanofibers based on polyvinyl alcohol and chitosan (PVA/chitosan) has been carried out by means of electrospinning with focusing on beads formation and diameter variation due to effects of weight ratio variations of PVA/chitosan. For electrospinning solution, the PVA/chitosan with artios of 10:1, 10:2 and 10:3 w/w were dissolved in 1% acetic acid. In addition, stability testing of PVA/chitosan nanofibers in an electrolyte solution was performed by soaking the nanofiber mat in KOH solution. As results, the addition of chitosan concentration increased the pH, conductivity, and viscosity of the solution. Beads were potentially generated for low chitosan concentration. Furthermore, the effect of viscosity and conductivity on diameter of electrospun nanofibers is very significant and need to be optimized. The average diameter of electrospun nanofibers were found to be 160 ± 18 nm, 120 ± 12 nm, and 148 ± 26 nm, for weight ratios of PVA and chitosan 10:1, 10:2 and 10:3, respectively. In addition, no significant change in morphology after being soaked the electrospun PVA/chitosan nanofibers in KOH 40 wt% solution for 24 hours. It indicates that the electrospun PVA/chitosan nanofibers is stable in electrolyte solution which shows a high potential for electrolyte membrane in fuel cells application.

Fabrication of Capsaicin Loaded Polyvinyl Alcohol Electrospun Nanofibers

2011 ◽  
Vol 338 ◽  
pp. 42-45 ◽  
Author(s):  
Tanasait Ngawhirunpat ◽  
Theerasak Rojanarata ◽  
Suwannee Panomsuk ◽  
Praneet Opanasopit
Keyword(s):  
Drug Delivery ◽  
Polyvinyl Alcohol ◽  
Drug Delivery System ◽  
Delivery System ◽  
Transdermal Drug Delivery ◽  
Electrospun Nanofibers ◽  
Dry Weight ◽  
Transdermal Drug Delivery System ◽  
Fiber Mats ◽  
Nanofiber Mats

The aim of this study was to prepare and characterize electrospun polyvinyl alcohol (PVA) nanofiber mats loaded with capsaicin (CC) as a transdermal drug delivery system. The amount of CC loaded in the base PVA solution (10 %w/v solution) was 0.025, 0.0375 and 0.05 %, based on the dry weight of PVA (% wt). The average diameters of these fibers ranged from 121 to 165 nm. In all concentrations of CC loaded in spun PVA fiber mats, an amorphous nanodispersion of CC with PVA was obtained. The tensile strength of the as-spun fiber mats was lower than that of the as-cast PVA films. The release rate of CC from CC-loaded as-spun PVA was significantly higher than from CC-loaded as-cast PVA films, and increased when the CC content in both CC-loaded as-spun PVA and CC-loaded as-cast PVA films increased. Our research suggests a potential use for CC-loaded electrospun PVA mats as a transdermal drug delivery system.

Optimization of Chitosan/PVA Concentration in Fabricating Nanofibers Membrane and its Prospect as Air Filtration

2017 ◽  
Vol 901 ◽  
pp. 20-25 ◽  
Author(s):  
Himayatus Shalihah ◽  
Ahmad Kusumaatmaja ◽  
Ari Dwi Nugraheni ◽  
Kuwat Triyana
Keyword(s):  
Electrospun Fiber ◽  
Chemical Compounds ◽  
Average Diameter ◽  
Air Filtration ◽  
Maximum Condition ◽  
Chemical Absorption ◽  
Fiber Mats ◽  
Before And After ◽  
Porosity Percentage ◽  
Scanning Electron

Chitosan/polyvinyl-alcohol (Chitosan/PVA) based nanofibers were successfully produced using electrospinning machine and investigated their application as air filtration. Firstly, 2 wt% chitosan was dissolved to 1 wt% acetic acid followed by mixing with PVA solution to produce fiber mats or membrane. Secondly, the morphology and diameter of the electrospun fiber were analyzed by using a scanning electron microscopy (SEM), while the chemical compounds in the membrane were characterized using Fourier transform infrared spectroscopy (FTIR). It was found that the conductivity of solution increased by the concentration of chitosan. Meanwhile, the average diameter and percentage of porosity decreased due to the upsurge of the conductivity of the solution. The average diameter of PVA 13 wt% was and the percentage of porosity were 50.32%. The maximum condition of chitosan/PVA was obtained at 20/80 wt%, in line with the average of fiber diameters and the percentage of porosity were 25.32%. Physicochemical properties of chitosan/PVA solution, such as conductivity, morphology, and chemical absorption were investigated before and after the air filtration. The porosity percentage of PVA 13wt% after air filtration changed to 35.85% and the percentage of porosity of chitosan/PVA 20/80 became 25.32%. Remarkable absorption peaks of PVA 13wt% exhibited and - shifted after the air filtration test, it was indicating that functional groups had been reduced. The chemical absorption of chitosan/PVA 20/80 wt% showed at the the region then disappeared after the air filtration test.

SILICON CARBIDE NANOWIRES FROM POLYVINYL ALCOHOL/SILICA ELECTROSPUN NANOFIBERS

NANO ◽  
2011 ◽  
Vol 06 (01) ◽  
pp. 41-45 ◽  
Author(s):  
H. DELAVARI H. ◽  
M. KOKABI
Keyword(s):  
Electron Microscopy ◽  
Silicon Carbide ◽  
Polyvinyl Alcohol ◽  
Gas Flow ◽  
Electrospun Nanofibers ◽  
Average Diameter ◽  
Sic Nanowires ◽  
Transmission Electron ◽  
Temperature Scanning ◽  
Vs Mechanism

The catalyst-free synthesis of silicon carbide (SiC) nanowires was carried out from polyvinyl alcohol (PVA)/silica electrospun nanofibers at high temperature. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray powder diffraction (XRD), and thermogravimetery analysis (TGA) were employed to study morphology and formation of SiC nanowires. Based on the TGA analysis, the carbon yield was increased when inert gas flow rate and heating rate decreased and polymeric nanofibers has been stabilized. The XRD and TEM results showed that the produced nanowires were crystalline β- SiC and rather homogeneous in thickness with an average diameter around 50 to 70 nm and a length of more than 10 μm. Finally, a possible growth mechanism of β- SiC nanowire based on a vapor–solid (VS) mechanism was proposed.

scholarly journals Characterization, Antibacterial and Anti-Inflammatory Activities of Electrospun poly (vinyl alcohol) (PVA) Containing Aquilaria malaccencis Leaf Extract (ALEX) Nanofibers

2020 ◽  
Vol 9 (3) ◽  
pp. 541-548
Keyword(s):  
Vinyl Alcohol ◽  
Wound Dressing ◽  
Leaf Extract ◽  
Vibrio Vulnificus ◽  
Electrospun Nanofibers ◽  
Poly Vinyl Alcohol ◽  
Scanning Calorimetry ◽  
Swelling Degree ◽  
Anti Inflammatory ◽  
Nanofiber Mats

Plant-based electrospun nanofibers are widely fabricated as wound dressing in recent years primarily due to the presence of bioactive compounds which can facilitate the wound healing effects. In this study, poly(vinyl alcohol) (PVA) fibre mats containing Aquilaria malaccensis leaf extract (ALEX) [5, 10 and 15 %(w/w)] were fabricated by electrospinning method as potential wound dressing material. The nanofibers were uniform, beadless and randomly oriented with average diameters ranged between 195.27 – 281.20 nm. The presence of ALEX in the PVA nanofibers were evaluated by Attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR) and differential scanning calorimetry (DSC). The mechanical properties, swelling degree and weight loss of nanofiber mats were also determined. ALEX was rapidly released from the ALEX-loaded PVA nanofibers in the first 12 hours and increased gradually afterwards. The released rate of ALEX was dependent on the ALEX content in the PVA nanofibers. This result is also contributed by the swelling degree and porosity of the nanofibers where the results were found to be between 241.66 – 305.86% and 64.53 – 30.81%, respectively. Meanwhile, the tensile stress and maximum elongation at break for all electrospun nanofiber mats were in the range of 8.56 – 2.68 MPa and 205.94 – 166.31%, respectively. The nanofiber mats inhibited growth of Escherichia coli, Vibrio vulnificus, Bacillus subtilis and Staphylococcus aureus with zone of inhibition of 7.5 - 15.0 mm for gram positive bacteria and 6.1 - 11.7 mm for gram negative bacteria. ALEX-loaded PVA nanofibers also showed potent anti-inflammatory activity against lipoxygenase with percentage of inhibition between 80.887 – 86.977%. Taken together, the results of this study suggest that ALEX-loaded PVA nanofibers have the desired properties of bioactive wound dressing.

scholarly journals Effects of Dopant Types and Contents on Morphology and Strength Properties of PANI/PAN Electrospun Nanofibers

2018 ◽  
Vol 237 ◽  
pp. 02016
Author(s):  
Taohai Yan ◽  
Jinhua Jiang ◽  
Nanliang Chen
Keyword(s):  
Electrospun Fiber ◽  
Reference Value ◽  
Electrospun Nanofibers ◽  
Basic Research ◽  
Average Diameter ◽  
Maximum Intensity ◽  
Small Range ◽  
Fiber Membrane ◽  
Pan Fiber ◽  
Doped Polyaniline

In this paper, the electrospinning of polyaniline under different dopant conditions were studied, the experimental phenomena was introduced, analyzed the relationship between the nanofiber surface morphology of DBSA-PANI/PAN, HCl-PANI/PAN and PTSA-PANI/PAN membranes and dopant type and content. The average diameter of DBSA-PANI/PAN electrospinning fiber membrane showed a decreasing trend when the content of doped polyaniline increased 1%-4%, and reached a minimum value of 780nm when the concentration was 4%. The strength of DBSA-PANI/PAN fiber membrane was the highest when the concentration of doped polyaniline was 1%, and the maximum intensity was 1.8×10 5 Pa. The average diameter of HCl/PANI/PAN fiber membranes decreases with the increase of doped polyaniline concentration, and it fluctuates up and down within a small range. When the content of doped polyaniline was increased to 4%, the average fiber diameter reached a minimum of 420 nm. The strength of the HCl-PANI/PAN fiber membrane was the highest when the concentration of doped polyaniline was 4%, and the maximum intensity was 1.08×10 5 Pa. The average diameter of the PTSA-PANI/PAN electrospun fiber membrane was the smallest at 2% doped polyaniline content and was 430 nm, the strength of PTSA-PANI/PAN fiber membrane is the highest when the content of doped polyaniline is 2%, and the maximum intensity is 3.9×10 4 Pa. In this paper, the basic research of doped polyaniline electrospinning nanofibers has made a useful supplement to the existing research of polyaniline nanofibers, and has a reference value for the application of polyaniline.

Deposition of MOFs on Polydopamine-Modified Electrospun Polyvinyl Alcohol/Silica Nanofibers Mats for Chloramphenicol Adsorption in Water

NANO ◽  
2020 ◽  
Vol 15 (04) ◽  
pp. 2050046 ◽  
Author(s):  
Aowen Li ◽  
Meimei Zhou ◽  
Pingping Luo ◽  
Jiaxin Shang ◽  
Pengbo Wang ◽  
...  
Keyword(s):  
Polyvinyl Alcohol ◽  
Specific Surface ◽  
Surface Area ◽  
Specific Surface Area ◽  
Electrospun Nanofibers ◽  
Silica Network ◽  
Inorganic Hybrid ◽  
Application Range ◽  
Hybrid Nanofiber ◽  
Nanofiber Mats

Nanofiber mats produced by electrospinning, with the advantages of specific surface area, porosity and chemical tenability, are an ideal support material for deposition of metal[Formula: see text]organic framework (MOF) crystals. In this study, four types of MOFs (MIL-53(Al), ZIF-8, UiO-66-NH2 and NH2-MIL-125(Ti)) were deposited on polydopamine (PDA)-modified electrospun polyvinyl alcohol (PVA)/SiO2 organic[Formula: see text]inorganic hybrid nanofiber mats by bulky synthesis. Because of the formation of Si–O–C–O–Si bridges between PVA chains and silica network, electrospun PVA/SiO2 organic[Formula: see text]inorganic hybrid nanofiber mats are quite stable in water or organic solvents and at high temperature are suitable as supports for MOFs deposition. The PDA layer, which exhibits a powerful adhesive ability to attach foreign objects, can effectively improve growth of MOFs on the surface of PVA/SiO2 nanofiber mats. The obtained MOF composites combining the unique properties of electrospun nanofibers mats and MOFs particles become flexible and tailorable, greatly expanding the application range of MOFs materials. The synthesized MOF composites were used to adsorb chloramphenicol (CAP) in water. It was found that the four MOF composites could remove CAP from water effectively and MIL-53(Al) composite had the highest adsorption capacity due to the higher specific surface area.

scholarly journals Post-electrospinning crosslinking of guar/polyvinyl alcohol membrane

2016 ◽  
Vol 20 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Jingjing Shi ◽  
Enlong Yang
Keyword(s):  
Heat Treatment ◽  
Citric Acid ◽  
Polyvinyl Alcohol ◽  
Guar Gum ◽  
Weight Ratio ◽  
Average Diameter ◽  
Alcohol Solution ◽  
Electrospun Nanofiber ◽  
Ft Ir ◽  
Nanofiber Membranes

College of Material and Textile Engineering, Jiaxing University, Jiaxing, China The present study reports post-electrospinning crosslinking of guar/polyvinyl alcohol (PVA)/citric acid nanofiber membranes by heat treatment. Porous, interconnected nonwoven nanofiber membranes (average diameter 194?23 nm) were electrospun from a homogeneous blend of 1wt% guar gum and 8wt% polyvinyl alcohol solution (3:7 weight ratio) containing 5 wt% (by the total weight of the solution) citric acid. The electrospun nanofiber membranes were then cured at 140 oC for 2 h. The crosslinked nanofiber membranes were insoluble in water, while the non-crosslinked membranes dissolved instantaneously. FT-IR spectrum investigates that crosslinking of guar/PVA occurred through esterfication reaction during heat treatment.

A Hydroxyapatite-Collagen Composite Useful to Make Bioresorbable Scaffolds for Bone Reconstruction

2010 ◽  
Vol 76 ◽  
pp. 133-138 ◽  
Author(s):  
Giulio D. Guerra ◽  
Caterina Cristallini ◽  
Elisabetta Rosellini ◽  
Niccoletta Barbani
Keyword(s):  
Weight Ratio ◽  
Average Diameter ◽  
Cross Linking ◽  
Bone Reconstruction ◽  
Scanning Calorimetry ◽  
Bioresorbable Scaffolds ◽  
Micro Particles ◽  
Ft Ir ◽  
The Cross ◽  
The Stability

Composites between hydroxyapatite (HA) and collagen (Col) may be used to make bioresorbable scaffolds for bone reconstruction. A suspension of micro-particles (average diameter ≅ 30 µm) of HA annealed at 1100°C in Col solution (80:20 HA to Col weight ratio) was manufactured in films by casting, and then some films were cross-linked by glutaraldehyde vapours. Cross-linked sponges were obtained by treating the suspension with transglutaminase, and by lyophilizing the so obtained gel. Characterization by scanning electron microscopy, water sorption test, Col release in water, thermogravimetric analysis and differential scanning calorimetry shows that the cross-linking enhances the stability of the composite. Conversely, neither the interactions between HA and Col, detected by spotlight FT-IR, nor the degradation by collagenase, which is a requirement for the bioresorbibility, are affected by the cross-linking.

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