Development and Characterization of Hydroxyapatite Containing Silver by Precipitation and Immersion Methods

2014 ◽  
Vol 631 ◽  
pp. 216-221
Author(s):  
M.F. Santos ◽  
L.C.O. Vercik ◽  
A. Vercik ◽  
E.C.S. Rigo
Keyword(s):  
Bacterial Infections ◽  
Antibacterial Properties ◽  
Silver Ions ◽  
Antimicrobial Effect ◽  
Bone Substitutes ◽  
Precipitation Method ◽  
Precipitation Process ◽  
X Ray Diffraction ◽  
Ionic Groups ◽  
Conventional Antibiotics

The use of bone substitutes for recovery of lost function is a constant search within the medical field. So biomaterials have received a very large attention from the scientific community, including the materials the basis of calcium phosphate. Hydroxyapatite (HA) has been studied as apart from representing the natural constitution of the mass of bones and teeth in 30 to 70 %, has properties of bioactivity and osteoconductivity, encouraging and assisting the growth of bone tissue. In contrast, bacterial infections can arise after implantation causing the loss of functionality in the short and medium term. Several alternatives are being tested, usually associated with the use of conventional antibiotics incorporated into biomaterials. An alternative to antibiotics would be use such metals that possess antibacterial properties. Silver (Ag) is known as a bactericidal metal and so gained a prominent place among the studies as an important ally in the control of post-surgical infections. This work aimed to synthesize, characterize and evaluate the antimicrobial effect of the addition of silver ions into hydroxyapatite. The hydroxyapatites containing silver were obtained by the precipitation method in aqueous solution containing AgNO3 and by immersing the powder after the precipitation process in aqueous solutions containing AgNO3. At this stage of the work, were analyzed and characterized the crystalline phases and the ionic groups present in HA, HA precipitates with Ag and immersed in a solution of Ag. X-ray diffraction (XRD) spectra showed that regardless of the method used, precipitation (room temperature or 90°C) or by immersion, the metallic Ag was present in the structure of HA. Additionally, it was observed that the peaks indicated in the XRD pattern for HA corresponding to the diffraction pattern of plugs JPCDS 09-0432 (Joint Committee on Powder Diffraction Standards). No peaks related to the phases being observed β-TCP and CaO, respectively, indicating that the conditions adopted for obtaining HA Ag, only HA phase is present and that methods, precipitation and immersion are efficient to occur doping of HA with Ag

scholarly journals Synthesis and Characterization of Hydroxyapatite from Duck Eggshell by Wet Precipitation Process

2021 ◽  
Vol 3 (1) ◽  
pp. 8-11
Author(s):  
Yelmida Azis ◽  
Cory Dian Alfarisi ◽  
Komalasari Komalasari ◽  
Khairat Khairat ◽  
Yusnimar Sahan
Keyword(s):  
Xrd Analysis ◽  
Precipitation Method ◽  
Molar Ratio ◽  
Precipitation Process ◽  
Stable Form ◽  
X Ray Diffraction ◽  
Precipitated Calcium Carbonate ◽  
X Ray ◽  
Inorganic Mineral

Hydroxyapatite (HAp, Ca10(PO4)6(OH)2) is the most stable form of calcium phosphate and widely used in various medical applications, mainly in orthopedics and dentistry due to its close similarities with the inorganic mineral component of bone and teeth. This study aims to synthesize hydroxyapatite from duck eggshell using the precipitation method. The duck eggshell was calcined, hydrated (slaking) and underwent carbonation to form Precipitated Calcium Carbonate (PCC).  Afterwards, (NH4)2HPO4 was added to produce HAp by varying the molar ratio of Ca/P by 1.67, 1.77 and 1.87 and stirring speed by 200, 250, 300rpm under basic condition (pH 10 – 11). The best results were obtained at a molar ratio of 1.77 with 200rpm stirring speed. Furthermore, the X-ray Diffraction (XRD) analysis showed that its crystals were hexagonal with sizes of 23.062nm, in the absence of other crystalline phases. Therefore, the hydroxyapatite was obtained in the agglomerates form with a specific surface area of ??55.929m2/g.

scholarly journals Optimization analysis of separation conditions of washed water containing a lead complex and characterization of the precipitation products

2017 ◽  
Vol 76 (12) ◽  
pp. 3220-3226 ◽  
Author(s):  
Wenmin Cai ◽  
Jiajun Chen ◽  
Qingwei Wang ◽  
Meng Wei
Keyword(s):  
Reaction Time ◽  
Environmental Governance ◽  
Sodium Sulfide ◽  
Precipitation Method ◽  
Molar Ratio ◽  
Precipitation Process ◽  
Process Conditions ◽  
Precipitation Reaction ◽  
Reaction Products ◽  
X Ray Diffraction

Abstract Presently, the large amount of industrial leaded wastewater creates a great challenge to both environmental governance and wastewater recycling. Lead complexes in washed water must be removed mostly before the washed water can be recycled. This paper reports the mechanism and factors of removing Pb complexes in simulated washed water by the sulfide precipitation method. The reaction time, sodium sulfide dosage, pH, and polymeric aluminum chloride (PAC) dosage were analyzed and the optimal conditions were explored. The composition of the reaction products was also verified by scanning electron microscopy (SEM) and X-ray diffraction (XRD). Additionally, the kinetics of the precipitation reaction of sodium sulfide and Pb-EDTA were studied. These results showed that the Pb removal efficiency reached 91.7% under the optimal process conditions which were as follows: the dosages of Na2S and PAC were 188 mg/L (Na2S/Pb2+ molar ratio of 5:1) and 30 mg/L, respectively, the reaction time was 40 min, and the pH was 9. It was demonstrated using SEM and XRD that the reaction product in the separation process was PbS and the precipitation process was fitted to the following first-order reaction kinetics equation: Ct = 89.1e−0.1047t + 10.1 (R2 = 0.9929; Ct is Pb concentration at reaction time t).

Preparation of Antibacterial Polypeptides with Different Topologies and Their Antibacterial Properties

2022 ◽  
Author(s):  
Xiaodan Wang ◽  
FangPing Yang ◽  
Huawei Yang ◽  
Xu Zhang ◽  
Haoyu Tang ◽  
...  
Keyword(s):  
Antimicrobial Peptides ◽  
Bacterial Infections ◽  
Antimicrobial Agents ◽  
Antibacterial Properties ◽  
Conventional Antibiotics

Antimicrobial peptides (AMPs) are attractive antimicrobial agents used to combat bacterial infections and have been advanced to be one of the most promising alternatives to conventional antibiotics. They stand out...

Characterization and antibacterial properties of Eriobotrya japonica extract loaded silver-nanoparticles

2020 ◽  
Vol 16 ◽  
Author(s):  
Arfaa Sajid ◽  
Qaisar Manzoor ◽  
Anam Sajid ◽  
Muhammad Imran ◽  
Shanza Khalid ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Green Synthesis ◽  
Antibacterial Properties ◽  
Antimicrobial Properties ◽  
Silver Ions ◽  
Eriobotrya Japonica ◽  
X Ray Diffraction ◽  
Effective Utilization ◽  
E Coli ◽  
Elongated Nanoparticles

Background:: Currently, developing methods for the formation of nanoparticles with antimicrobial properties based on green chemistry are the research hotspots. In this research green biosynthesis of Eriobotrya japonica extract loaded silver nanoparticles and their characterization were the main objectives to achieve. Methods:: Green synthesis of E. japonica leaves extract-loaded silver nanoparticles (AgNPs) was carried out and its effect on bacterial growth was examined. The reduction of silver ions in solution was observed using UV-Vis spectrophotometer. The properties of AgNPs were assessed using Scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD). Also, their antibacterial effects were checked against Staphylococcus aureus and Escherichia coli. Results:: It was revealed that 5-50 nm sized spherical to elongated nanoparticles were synthesized that possessed comparatively better antibacterial potential against E. coli and S. aureus than conventional extract of the E. japonica leaves. Conclusions:: Green synthesis and effective utilization of Eriobotrya japonica extract loaded silver nanoparticles is a promising approach for nanoparticle production avoiding negative environmental impacts.

scholarly journals Development of Multifunctional Materials Based on Poly(ether ether ketone) with Improved Biological Performances for Dental Applications

Materials ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 1047
Author(s):  
Vanessa Montaño-Machado ◽  
Pascale Chevallier ◽  
Linda Bonilla-Gameros ◽  
Francesco Copes ◽  
Chiara Quarta ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Zno Nanoparticles ◽  
Bacterial Infections ◽  
Antibacterial Properties ◽  
X Ray Diffraction ◽  
Scanning Calorimetry ◽  
Ether Ether Ketone ◽  
Poly Ether Ether Ketone ◽  
Ether Ketone ◽  
Dental Applications

The main target for the future of materials in dentistry aims to develop dental implants that will have optimal integration with the surrounding tissues, while preventing or avoiding bacterial infections. In this project, poly(ether ether ketone) (PEEK), known for its suitable biocompa-tibility and mechanical properties for dental applications, was loaded with 1, 3, and 5 wt.% ZnO nanoparticles to provide antibacterial properties and improve interaction with cells. Sample cha-racterization by X-ray diffraction (XRD), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC) as well as mechanical properties showed the presence of the nanoparticles and their effect in PEEK matrices, preserving their relevant properties for dental applications. Al-though, the incorporation of ZnO nanoparticles did not improve the mechanical properties and a slight decrease in the thermal stability of the materials was observed. Hemocompatibility and osteoblasts-like cell viability tests showed improved biological performances when ZnO was present, demonstrating high potential for dental implant applications.

scholarly journals Antibacterial Coating for Elimination ofPseudomonas aeruginosaandEscherichia coli

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Zainal Abidin Ali ◽  
W. Ahliah Ismail ◽  
Cheng-Foh Le ◽  
Hassan Mahmood Jindal ◽  
Rosiyah Yahya ◽  
...  
Keyword(s):  
Photoelectron Spectroscopy ◽  
Antibacterial Properties ◽  
Precipitation Method ◽  
Gram Negative Bacteria ◽  
Coating System ◽  
Silver Particles ◽  
X Ray Diffraction ◽  
X Ray ◽  
Ag Particles ◽  
Antibacterial Surface

A polymer antibacterial surface has been successfully developed. The coating system used silane as binder and Ag particles as antibacterial agent. The silver was synthesized using precipitation method. X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), Brunauer-Emmett-Teller (BET) tests, energy-dispersive X-ray spectroscopy (EDX), and X-ray photoelectron spectroscopy (XPS) were carried out to evaluate the silver particles. Antibacterial properties of the coating system were tested against gram-negative bacteria, namely,Pseudomonas aeruginosaandEscherichia coli. Different amounts of Ag were used in the coating to optimize its usage. The Japanese International Standard, JISZ2801, was used for bacteria test and the surface developed complies with the standard being antibacterial.

Complexional Ultrafine Zinc Oxide Powders Prepared by Controlled-Release Precipitation

2011 ◽  
Vol 306-307 ◽  
pp. 1369-1374
Author(s):  
Zhi Fang Tong ◽  
Yinq Jie Li ◽  
Li Xiu Lian
Keyword(s):  
Zinc Oxide ◽  
Controlled Release ◽  
Average Particle Size ◽  
Ammonia Solution ◽  
Precipitation Method ◽  
Precipitation Process ◽  
Average Particle ◽  
X Ray Diffraction ◽  
Oxide Powders ◽  
Wide Range

The synthesis of complexional ultrafine zinc oxide powders by controlled-release precipitation method, which is a precipitation process of precursor by controlling ammonia distillation rate in ammonia solution under the combination effect of microwave heating and ultrasonic cavitating, and followed by subsequent heat treatment was investigated. The characteristic of precursor and zinc oxide powders were studied using X-ray diffraction, scanning electron microscopy, TG-DTA-DTG, FT-IR, and ultraviolet-visible pectrophotometer. The coloring mechanism of complexional zinc oxide is discussed. This has shown that a tentative composition of the precursor is likely Zn3CO3(OH)4·H2O. Complexional zinc oxide particles of an average particle size of 200 nm with narrow size distribution, good dispersibility and hexagonal appearance could be obtained after annealing at 350°C for 1.5 hour. ZnO particles are complexional, probably due to nitrogen atom or N-H bond entering into crystal lattice of zinc oxide. Complexional zinc oxide has fine capacity of shielding UV and absorbing wide range of wavelength.

scholarly journals Insect Antimicrobial Peptides, a Mini Review

Toxins ◽  
2018 ◽  
Vol 10 (11) ◽  
pp. 461 ◽  
Author(s):  
Qinghua Wu ◽  
Jiří Patočka ◽  
Kamil Kuča
Keyword(s):  
Antimicrobial Peptides ◽  
Bacterial Infections ◽  
Synergistic Effects ◽  
Biological Effects ◽  
Antimicrobial Effect ◽  
Innate Immune ◽  
First Line ◽  
Hydrophobic Property ◽  
Toroidal Pore ◽  
Conventional Antibiotics

Antimicrobial peptides (AMPs) are crucial effectors of the innate immune system. They provide the first line of defense against a variety of pathogens. AMPs display synergistic effects with conventional antibiotics, and thus present the potential for combined therapies. Insects are extremely resistant to bacterial infections. Insect AMPs are cationic and comprise less than 100 amino acids. These insect peptides exhibit an antimicrobial effect by disrupting the microbial membrane and do not easily allow microbes to develop drug resistance. Currently, membrane mechanisms underlying the antimicrobial effects of AMPs are proposed by different modes: the barrel-stave mode, toroidal-pore, carpet, and disordered toroidal-pore are the typical modes. Positive charge quantity, hydrophobic property and the secondary structure of the peptide are important for the antibacterial activity of AMPs. At present, several structural families of AMPs from insects are known (defensins, cecropins, drosocins, attacins, diptericins, ponericins, metchnikowins, and melittin), but new AMPs are frequently discovered. We reviewed the biological effects of the major insect AMPs. This review will provide further information that facilitates the study of insect AMPs and shed some light on novel microbicides.

scholarly journals Study of the Structure and Antimicrobial Activity of Ca-Deficient Ceramics on Chlorhexidine Nanoclay Substrate

Materials ◽  
2019 ◽  
Vol 12 (18) ◽  
pp. 2996 ◽  
Author(s):  
Lenka Pazourková ◽  
Magda Reli ◽  
Marianna Hundáková ◽  
Erich Pazdziora ◽  
Daniela Predoi ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Antimicrobial Effect ◽  
Precipitation Process ◽  
X Ray Diffraction ◽  
Spectroscopy Analysis ◽  
Modified Montmorillonite ◽  
Organically Modified Montmorillonite ◽  
Organically Modified ◽  
Bacteria And Fungi

Novel biomedical composites, based on organically modified vermiculite and montmorillonite with deposited Ca-deficient hydroxyapatite (CDH), were prepared. The monoionic sodium forms of vermiculite and montmorillonite were intercalated with chlorhexidine diacetate (CA). The surfaces of organoclays were used for the precipitation of Ca-deficient hydroxyapatite. The composites with Ca-deficient hydroxyapatite showed very good antibacterial effects, similar to the antimicrobial activity of pure organoclay samples. Better antibacterial activity was shown in the organically modified montmorillonite sample with Ca-deficient hydroxyapatite compared with the vermiculite composite, but, in the case of Staphylococcus aureus, both composites showed the same minimum inhibitory concentration (MIC) value. The antimicrobial effect of composites against bacteria and fungi increased with the time of exposure. The structural characterization of all the prepared materials, performed using X-ray diffraction and FT infrared spectroscopy analysis, detected no changes in the original clay or CDH during the intercalation or precipitation process, therefore we expect the strength of the compounds to be in the original power.

Preparation of Nickel and Manganese Oxides Composite via Co-Precipitation Method and its Supercapacitive Performance

2017 ◽  
Vol 727 ◽  
pp. 770-774
Author(s):  
Zhong Yang Wang ◽  
Run Hua Fan ◽  
Qian Qian Li ◽  
Lei Qian
Keyword(s):  
Specific Capacitance ◽  
Manganese Oxides ◽  
Electrical Impedance Spectroscopy ◽  
Precipitation Method ◽  
Precipitation Process ◽  
X Ray Diffraction ◽  
Nickel Oxides ◽  
Supercapacitive Performance ◽  
Eis Measurements ◽  
Co Precipitation

The nickel and manganese oxides (Ni-Mn oxides) were prepared by a simple co-precipitation process with sodium carbonate (Na2CO3) as precipitant. The products are the mixture of nickel oxides, manganese oxides and their solid solution. The phase and morphology of the synthesized product were characterized by X-ray diffraction and field emission scanning electron microscope. The electrochemical capacitive characterization was performed using cyclic voltammetry (CV), galvanostatic charge/discharge (GCD) and electrical impedance spectroscopy (EIS) measurements in a 6mol/L KOH aqueous solution electrolyte. The result shows that a maximal specific capacitance value when stoichiometric amounts of NiCl2 and MnCl2 are equal (cationic ratio of Ni:Mn=1:1) which the specific capacitance is 110 F/g (at a current density of 1A/g). Overall we found that the nickel and manganese oxides have better electrochemical performance compared to the single parts, and while the introduction of nickel oxides can further improve the performance.

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