scholarly journals COVID-19 reinfection - An enigmatic public health threat

2020 ◽  
Vol 90 (4) ◽  
Author(s):  
Karthikeyan P. Iyengar ◽  
Vijay Kumar Jain ◽  
Pranav Ish

To the Editor The COVID-19 pandemic has been consistently on the rise across the globe. The recovered patients getting long-term sequelae, especially lung fibrosis and residual neurological deficits, is an area of concern. Another extremely important conundrum is the risk of re-infection. It has been recently documented from Hong Kong  and puts an unpleasant question mark on long term immunity, sampling technique standardization, viral mutation and efficacy of herd immunity. There are definitions for COVID -19 infection and its severity, but unfortunately none for re-infection.

2019 ◽  
Vol 21 (1) ◽  
pp. 93-99

With the aging of the population, Alzheimer disease (AD) has become an epidemic and a major public health threat. Hundreds of molecules tested in clinical trials in the last decade to treat AD have failed, moving the field to examine the clinical and neurobiological value of prevention of cognitive decline and AD. This short review describes recently finished or currently ongoing clinical trials for prevention of AD, both their main outcomes and secondary outcomes. In addition, the potential modifying effects of age and of genetics as important factors that may affect the design of future clinical trials is discussed. Finally, we discuss the development of new molecular imaging and of digital technologies as a means to disclosure of dementia-related risk and disease progress, and their potential importance as contributors to adherence to healthy lifestyle for the prevention or delay of AD onset.


2020 ◽  
pp. 140349482096129 ◽  
Author(s):  
Theodore Lytras ◽  
Sotirios Tsiodras

An overall long-term strategy for managing the coronavirus disease 2019 (COVID-19) pandemic is presented. This strategy will need to be maintained until herd immunity is achieved, hopefully through vaccination rather than natural infection. We suggest that a pure test-trace-isolate strategy is likely not practicable in most countries, and a degree of social distancing, ranging up to full lockdown, is the main public-health tool to mitigate the COVID-19 pandemic. Guided by reliable surveillance data, distancing should be continuously optimised down to the lowest sustainable level that guarantees a low and stable infection rate in order to balance its wide-ranging negative effects on public health. The qualitative mixture of social-distancing measures also needs to be carefully optimised in order to minimise social costs.


2017 ◽  
Vol 5 (1) ◽  
pp. 10
Author(s):  
Asti Dewi Rahayu Fitrianingsih ◽  
Soenarnatalina Melaniani

Long term contraception entered into government programs. Government suggested to use long term contraception effectively to postponing pregnancy, spacing of birth and terminating fertility. In fact, couples of reproductive ages in Indonesia were likely to still choose short-term contraceptive than long-term contraceptive. This research analyzed sosiodemografi factors that aff ecting the selection of contraception method in Gading Public Health Center Tambaksari Surabaya. This research used analytical study with case control design. Research population totaled 84 respondents. Sampling technique used simple random sampling and got 42 cases and 42 controls. The variables were sosiodemografi factors. Data were analyzed using that multivariate logistic regression with a level of signifi cance value α = 0,05. The results showed four signifi cant variables were age (p=0,018), education (p=0,024), occupation (p=0,008), parity (p=0,034), also status of women (p=0,002. Sosiodemografi factors such as age, occupation, parity and status women aff ect the injection contraceptive acceptors did not choose long acting contraception method in Tambaksari Surabaya Gading Public Health Center. The granting of complete information about all types of contraception is important so that the fertile age couples can choose contraception that suits their need.


Author(s):  
Turkistani Fatema ◽  
Sawad Aseel Bin

Many countries resorted to the lockdown model that includes shutting down all non-essential activities to avoid the spread of COVID-19. Comparatively, Sweden applied the herd immunity model. The aim of this study is to analyze the Swedish model compared to the lockdown model based in other countries to understand the impact of these models on public health, health economics and overall economy of the respective countries. Based on the findings, the paper aims to shed light on which model proves to be more effective to cope with the pandemic and provide recommendations for other countries to follow accordingly. Our methodology was a narrative review that synthesizes current literature obtained from searches on various databases, authoritative texts, and hand searches. While it is too early to determine the long term effects of both models, it seems that Sweden’s herd immunity model is more effective considering aspects of overall public health, health economic factors, and the overall economy. The major cons of the Swedish model was a failure in controlling infection spread in elderly nursing homes, as half the death toll comprises individuals belonging to this community. While Sweden was able to soften the effect of COVID-19 impact on its economy without a lockdown, the manufacturing industry was impacted due to lack of availability of required parts to be supplied by other countries. Thus from our review , we found that Herd-immunity model is more effective, but it depends on other factors of the country such as population density, as it is not plausible for countries such as Spain, the US or Germany, which need to expose high numbers of people to COVID-19 to attain herd immunity.


2019 ◽  
Vol 21 (1) ◽  
pp. 93-99

With the aging of the population, Alzheimer disease (AD) has become an epidemic and a major public health threat. Hundreds of molecules tested in clinical trials in the last decade to treat AD have failed, moving the field to examine the clinical and neurobiological value of prevention of cognitive decline and AD. This short review describes recently finished or currently ongoing clinical trials for prevention of AD, both their main outcomes and secondary outcomes. In addition, the potential modifying effects of age and of genetics as important factors that may affect the design of future clinical trials is discussed. Finally, we discuss the development of new molecular imaging and of digital technologies as a means to disclosure of dementia-related risk and disease progress, and their potential importance as contributors to adherence to healthy lifestyle for the prevention or delay of AD onset.


2018 ◽  
Vol 5 (4) ◽  
pp. 766
Author(s):  
Mohammed Alfageeh ◽  
Moneerah Bahran ◽  
Sultan Albargi ◽  
Ibrahim Althomali ◽  
Adnan Alzahrani ◽  
...  

Traumatic brain injury following head injury is a major public health problem that can result in significant long-term morbidity and mortality among adults and children worldwide. Emergency brain imaging is necessary for individuals subjected to traumatic brain injury to early detect treatable conditions. Prompt neurosurgical management of treatable conditions can prevent further damage and secondary neurological deficits. This will subsequently improve the outcome and reduce long-term disability. Computed Tomography (CT) of the brain is the investigation of choice for assessment of patients with head injury due to its availability, advantages, and sensitivity for multiple lesions following head trauma. This article will review and discuss the importance of CT imaging in evaluating patients with traumatic brain injury, its advantages, limitations, and prognostic values.


2019 ◽  
Vol 21 (1) ◽  
pp. 93-99

With the aging of the population, Alzheimer disease (AD) has become an epidemic and a major public health threat. Hundreds of molecules tested in clinical trials in the last decade to treat AD have failed, moving the field to examine the clinical and neurobiological value of prevention of cognitive decline and AD. This short review describes recently finished or currently ongoing clinical trials for prevention of AD, both their main outcomes and secondary outcomes. In addition, the potential modifying effects of age and of genetics as important factors that may affect the design of future clinical trials is discussed. Finally, we discuss the development of new molecular imaging and of digital technologies as a means to disclosure of dementia-related risk and disease progress, and their potential importance as contributors to adherence to healthy lifestyle for the prevention or delay of AD onset.


2021 ◽  
Author(s):  
Igor M L Pataro ◽  
Juliane F Oliveira ◽  
Marcelo M Morato ◽  
Alan A S Amad ◽  
Pablo I P Ramos ◽  
...  

The SARS-CoV-2 pandemic triggered substantial economic and social disruptions. Mitigation policies varied across countries based on resources, political conditions, and human behavior. In the absence of widespread vaccination able to induce herd immunity, strategies to coexist with the virus while minimizing risks of surges are paramount, which should work in parallel with reopening societies. To support these strategies, we present a predictive control system coupled with a nonlinear model able to optimize the level of policies to stop epidemic growth. We applied this system to study the unfolding of COVID-19 in Bahia, Brazil, also assessing the effects of varying population compliance. We show the importance of finely tuning the levels of enforced measures to achieve SARS-CoV-2 containment, with periodic interventions emerging as an optimal control strategy in the long-term.One-sentence summaryWe present an adaptive predictive control algorithm to provide optimal public health measures to slow the COVID-19 transmission rate.


2018 ◽  
Vol 18 (3) ◽  
pp. 559
Author(s):  
Arifarahmi Arifarahmi

Indonesia is the nation with the third largest population in the world. One way to control the population is with the family planning program. The strategy of the implementation of KB program is increase the use of long-term contraceptive methods (MKJP) sterilization (MOW and MOP), IUD and implant. The research used descriptive research; it aimed to determine perception of acceptor KB about use of long-term contraceptive methods at the public health center Koni Jambi city year 2017. Populations were 1.686 people. It used accidental sampling technique i.e. acceptor KB who visit the public health center. Sample for this research was 42 womens. Analyzed univariate was used for statistical analysis. The collecting data used by questionnaire. The result showed 9 acceptors (21%) used MKJP and 33 acceptors (79%) choose to use contraceptive non MKJP. 29 acceptors (69%) have positive perception and 13 acceptors (31%) have negative perception about use of long-term contraceptive methods. It concluded that there are many acceptor more choose and use contraception non MKJP, it suggested to increase promotion in conducting counseling about contraception to increase awareness of acceptor for themselves especially MKJP contraceptives.


Sign in / Sign up

Export Citation Format

Share Document