scholarly journals Anatomical locations of uterine fibroids in Sudanese women

2020 ◽  
Vol 9 (1) ◽  
pp. 1701-1706
Author(s):  
Mohammed A.A. Abdelmtalab ◽  
O. Tahir ◽  
K. Hussein ◽  
Kamal Badawi
Keyword(s):  
Smooth Muscle ◽  
Uterine Fibroid ◽  
Uterine Fibroids ◽  
Maternity Hospital ◽  
Benign Tumors ◽  
Uterine Neoplasms ◽  
Age Group ◽  
Single Mass ◽  
Posterior Position ◽  
Anterior Posterior

Uterine fibroids are the commonest uterine neoplasms, they are benign tumors of smooth muscle origin. The study was done to look for the  anatomical locations of uterine fibroids and their incidence in Sudanese women at Omdurman Maternity Hospital between 1st July 2014 to 5th October 2015. Their sociodemographic and ultrasound data were collected using a prepared questionnaire. The study included 138 confirmed cases of uterine fibroids out of 2968 investigated cases representing incidence rate of 4.6%. The highest incidence was found in the age group 36-40 years. Most dominant anatomical locations of uterine fibroids were intramural as a single mass (34.78%), followed by the intramural-subserosal in multiple masses (20.29%). The anatomical positions of uterine fibroids, posterior position was seen in (27.5%) which was the most dominant in single uterine fibroid mass, followed by the anterior-posterior position in multiple uterine one (18.1%). Intramural anatomical locations in single mass are the commonest uterine fibroids types which affect the Sudanese women. Key words: Anatomical locations; Uterine fibroid and leiomyomas

scholarly journals HEALTHY AND PATHOLOGICAL CHANGES OF MYOMETRIUM: PREGNANT MYOMETRIUM, UTERINE FIBROIDS AND LEIOMYOSARCOMA. Cambios normales y patológicos del miometrio: miometrio del embarazo, fibrosis uterina y leiomiosarcoma

2016 ◽  
Vol 4 (1) ◽  
pp. 7-13
Author(s):  
Pasquapina Ciarmela ◽  
Soriful Islam ◽  
Pasquale Lamanna ◽  
Andrea Tranquilli ◽  
Mario Castellucci
Keyword(s):  
Smooth Muscle ◽  
Uterine Fibroids ◽  
Present Review ◽  
Benign Tumors ◽  
Pathological Changes ◽  
Uterine Smooth Muscle ◽  
Smooth Muscle Tumors ◽  
In Pregnancy

El miometrio, la pared muscular del útero, puede modificar su misma masa y las propiedades celulares en el embarazo y también en los tumores como el leiomioma y el leiomiosarcoma. El leiomioma, dicho también fibroma, es un tumor benigno del útero y se considera como  una de las causas más frecuentes de infertilità en el período reproductivo femenino. El leiomiosarcoma, en cambio, es un tumor maligno y agresivo de la musculatura lisa uterina. La presente revisión discute las características generales del leiomioma y el leiomiosarcoma y los relativos tratamientos clínicos actualmente usados y además describe las características del miometrio normal en el embarazo.  The myometrium, the muscular wall of the uterus, can modify its mass and cellular properties in pregnancy as well as in tumor conditions such as leiomyoma and leiomyosarcoma. Leiomyomas, also known as fibroids, are benign tumors of the uterus, considered to be one of the most frequent causes of infertility in reproductive years of women. Leiomyosarcomas in turn, are rare aggressive malignant uterine smooth-muscle tumors. The present review is discussing the general features of leiomyoma and leiomyosarcoma with their current treatments and also discussing the characteristics of normal pregnant myometrium and compare with leiomyoma.

scholarly journals A case series of caesarean myomectomy

2021 ◽  
Vol 10 (9) ◽  
pp. 3580
Author(s):  
Shazia Parveen ◽  
Nasreen Noor ◽  
Iti Madan ◽  
Ummay Kulsoom
Keyword(s):  
Smooth Muscle ◽  
Caesarean Section ◽  
Observational Study ◽  
Cesarean Section ◽  
Patient Selection ◽  
Uterine Fibroid ◽  
Uterine Fibroids ◽  
Case Series ◽  
Operative Morbidity ◽  
Cesarean Myomectomy

Uterine fibroids are benign, monoclonal tumors of smooth muscle cells of the myometrium. Most fibroids do not increase in size during pregnancy and are not always removed when encountered during cesarean section. Objective was to see the outcome of patients undergoing cesarean myomectomy. The study design was observational study. All patients undergoing cesarean section with uterine fibroid of size more than 5 cm. In carefully selected patients and with use of intraoperative vasopressin, myomectomy may be safely accomplished at the time of caesarean section by experienced surgeons. cesarean myomectomy is safe and successful if patient selection is done carefully and does not add to any additional post-operative morbidity.

scholarly journals Effects of Herbal formulations in management of Uterine Fibroid (Sul’ah-E-Rehm) – A Case Report

2021 ◽  
Vol 5 (2) ◽  
pp. 91-97
Author(s):  
Mohammad Shamim Khan ◽  
Shaikh Imran ◽  
Mobashshera Khan
Keyword(s):  
Smooth Muscle ◽  
Case Report ◽  
Connective Tissue ◽  
Oral Administration ◽  
Uterine Fibroid ◽  
Uterine Fibroids ◽  
Fibrous Connective Tissue ◽  
Indian Women ◽  
Reproductive Life ◽  
Herbal Formulations

Uterine fibroid is the commonest benign and solid tumor in female during reproductive life. Approximately 15-25 million of Indian women have affected from fibroid uterus. Histologically itis composed of smooth muscle and fibrous connective tissue of varying proportional. It is considered as Sul’ah (tumor) in Unani classic litretures, as Ali Ibn-e-Abbas Majusi (930-994 AD) defined it under the topic of Warm-e-Balghami; as it is a swelling filled with viscid phlegm (Balgham-e-Ghaleez).Present paper deals with a reports of a 30 years old female having uterine fibroids measuring 2.6 cm× 3.1 cm, 2.6 cm× 3.6 cm, with left ovarian cyst of 3.1 cm × 4 cm. Patient was treated with herbal formulations; Majun Dabeedul Ward ( 5 gm paste), Kanchanar Guggul (2 tablet) and Niswani (10 ml syrup) twice a day for 8 consecutive weeks as oral administration. The patient was clinically assessed fortnightly, and radiologically just after treatment. Patient has shown encouraging result in post treatment investigation of Ultrasonography and finally patients got free from uterine fibroids without operation. The drugs were found to be safe and effective in this case.

scholarly journals The Immunohistochemical Expression of MCM-3, -5, and -7 Proteins in the Uterine Fibroids

2021 ◽  
Vol 43 (2) ◽  
pp. 802-817
Author(s):  
Piotr Rubisz ◽  
Lidia Hirnle ◽  
Christopher Kobierzycki
Keyword(s):  
Uterine Fibroid ◽  
Uterine Fibroids ◽  
Hormonal Contraceptives ◽  
Control Group ◽  
Proliferative Potential ◽  
Uterine Neoplasms ◽  
Minichromosome Maintenance ◽  
Ki 67 ◽  
Proliferative Markers ◽  
Positive Correlations

Uterine fibroids are the most common mesenchymal uterine neoplasms; their prevalence is estimated in 40%–60% of women under 35 and in 70%–80% of women over 50 years of age. The current research aims to focus on the etiopathogenesis of uterine fibroids, the factors that affect their growth, and markers with diagnostic and prognostic properties. The MCM (minichromosome maintenance) protein family consists of peptides whose primary function is participation in the molecular mechanism of creating replication forks while regulating DNA synthesis. The aim of this work was to determine the proliferative potential of uterine fibroid cells based on the expression of the Ki-67 antigen and the MCMs—i.e., MCM-3, MCM-5, and MCM-7. In addition, the expression of estrogen (ER) and progesterone (PgR) receptors was evaluated and correlated with the expression of the abovementioned observations. Ultimately, received results were analyzed in terms of clinical and pathological data. Materials and methods: In forty-four cases of uterine fibroids, immunohistochemical reactions were performed. A tissue microarray (TMA) technique was utilized and analyzed cases were assessed in triplicate. Immunohistochemistry was performed using antibodies against Ki-67 antigen, ER, PgR, MCM-3, MCM-5, and MCM-8 on an automated staining platform. Reactions were digitalized by a histologic scanner and quantified utilizing dedicated software for nuclear analysis. Assessment was based on quantification expression of the three histiospots, each representing one case in TMA. Results: In the study group (uterine fibroids), statistically significant stronger expression of all the investigated MCMs was observed, as compared to the control group. In addition, moderate and strong positive correlations were found between all tested proliferative markers. The expression of the MCM-7 protein also correlated positively with ER and PgR. With regard to clinical and pathological data, there was a negative correlation between the expression of MCMs and the number of both pregnancies and births. Significant reductions in MCM-5 and MCM-7 expression were observed in the group of women receiving oral hormonal contraceptives, while smoking women showed an increase in MCM-7, ER, and PgR. Conclusions: Uterine fibroid cells have greater proliferative potential, as evaluated by expression of the Ki-67 antigen and MCMs, than unaltered myometrial cells of the uterine corpus. The expression of MCM-7 was found to have strong or moderate correlations in all assessed relations. In the context of the clinical data, as well evident proliferative potential of MCMs, further studies are strongly recommended.

scholarly journals Is it safe to perform myomectomy in first trimester of pregnancy? The report of two cases

2021 ◽  
Vol 6 (2) ◽  
pp. 170-174
Author(s):  
Murat Celiloglu ◽  
◽  
Samican Ozmen ◽  
Sefa Kurt ◽  
Orkun Ilgen
Keyword(s):  
Uterine Fibroids ◽  
First Trimester ◽  
Reproductive Age ◽  
Benign Tumors ◽  
Age Group ◽  
Second Trimester ◽  
Review Of The Literature ◽  
First Trimester Of Pregnancy ◽  
Reproductive Age Group

Uterine fibroids are the most common benign tumors in women in the reproductive age group. The incidence of fibroids during pregnancy varies between 1.6 and 10.7%. In 10% of these cases, fibroids lead to complications. The management in symptomatic patients is conservative, and the surgical treatment is delayed until after birth due to its risks. In the last two decades, it has been shown that myomectomy can be an alternative treatment in selected cases, especially in second-trimester pregnancies. However, the data on the success of myomectomies performed earlier in pregnancy are limited. In this case report, we present two cases who were admitted to our clinic during the first trimester of pregnancy and had complicated fibroids. The diagnosis, the follow up and the treatment are presented with the review of the literature.

scholarly journals Predictors and symptomatic burden of uterine fibroids among women in South-Eastern India: a cross-sectional survey analysis

2019 ◽  
Vol 8 (2) ◽  
pp. 524
Author(s):  
Dharitri Swain ◽  
Chanchal Yadav ◽  
Jyoti Kumari ◽  
Monika Rani ◽  
Priyanka Daunrai Rongmei ◽  
...  
Keyword(s):  
Risk Factors ◽  
Uterine Fibroid ◽  
Uterine Fibroids ◽  
Overweight And Obesity ◽  
Reproductive Age ◽  
Age Group ◽  
Women Of Reproductive Age ◽  
Cross Sectional ◽  
Associated Risk Factors ◽  
Reproductive Age Group

Background: Uterine fibroid is the most common pelvic tumor in women of reproductive age and are asymptomatic in at least 50% of affected women. Various risk factors are associated with development of uterine fibroids during this reproductive age. The present study established various associated risk factors increases the prevalence of uterine fibroid among reproductive age group and clinical symptoms burden of diagnosed case.Methods: A cross sectional study design was used to collect samples for a period of six months in an OPD basis. Purposive sampling technique was used to select the 362 sample of reproductive age group (15-45 years) women in a tertiary care hospital, Southeastern India. Women diagnosed with uterine fibroid by ultrasonography were included as cases. Symptomatic features and associated risk factors of UF were collected through structure interview schedule.Results: Point prevalence of uterine fibroid among women in reproductive age group during the period of six months was 20%. Majority of them were in the age group of 30-39 years. Demographic factor such as overweight and obesity and consume dairy products daily has increased the prevalence of UF, whereas use of oral contraceptive pills and normal BMI had inverse relationship with UF risk. Most of the cases reported of having menstrual disturbances like heavy bleeding, passes blood clots during menstruation, prolonged period, urinary symptoms and pressure symptoms were considered independent predicting factors for the occurrence of uterine fibroid.Conclusions: Uterine fibroid is more prevalent among women of reproductive age causing various bleeding and renal symptoms that can have negative impact on quality of women’s life.

scholarly journals Spontaneous expulsion of a submucosal uterine fibroid without embolization in a pre-menopausal woman

2020 ◽  
Vol 8 ◽  
pp. 2050313X2092274
Author(s):  
Salete da Silva Rios ◽  
Jaqueline Santos Ribeiro ◽  
Marco Antonio de Souza Mota ◽  
Ana Carolina Rios Chen ◽  
Juliana Rios Chen ◽  
...  
Keyword(s):  
Uterine Fibroid ◽  
Correct Diagnosis ◽  
Uterine Fibroids ◽  
Rare Condition ◽  
Abnormal Uterine Bleeding ◽  
Benign Tumors ◽  
Menopausal Woman ◽  
Smooth Muscle Tissue ◽  
First Case ◽  
Spontaneous Expulsion

Uterine leiomyomas are benign tumors that develop from smooth muscle tissue and are present in up to 77% of women in menacme. They are often asymptomatic but can cause pelvic pain, compression, abnormal uterine bleeding, and degeneration. We present the first case report of a perimenopausal woman who exhibited complete and spontaneous expulsion of uterine fibroids without embolization or use of medication. She complained of a mass extruding from the vaginal orifice associated with bleeding and pain for a couple of hours. The anatomopathological findings showed a myomatous lesion. Complete expulsion of a uterine fibroid is a rare condition that may be associated with profuse hemorrhage and can pose a risk to the patient. When it occurs during perimenopause, it can mimic several clinical conditions. Therefore, gynecologists must remain alert to make the correct diagnosis and treatment.

Determinants of Uterine Fibroids Among Married Women Attending Public Hospitals in Lahore, Pakistan

2020 ◽  
pp. 33-37
Author(s):  
OJS Admin
Keyword(s):  
Smooth Muscle ◽  
Reproductive Tract ◽  
Uterine Fibroids ◽  
Married Women ◽  
Female Reproductive Tract ◽  
Public Hospitals ◽  
Benign Tumors

Uterine broids (leiomyomas) are the most common tumors of female reproductive tract; these are the benign tumors of smooth muscle. Fibroids have been reported to occur in up to 70% of women by the age of 50 years.

scholarly journals Spontaneous Rupture of a Leiomyoma Causing Life-Threatening Intra-Abdominal Hemorrhage

2017 ◽  
Vol 2017 ◽  
pp. 1-3 ◽  
Author(s):  
Melissa Schwartz ◽  
Kristin Powell
Keyword(s):  
Uterine Fibroid ◽  
Hypovolemic Shock ◽  
Clinical Manifestations ◽  
Uterine Fibroids ◽  
Acute Onset ◽  
Benign Tumors ◽  
Free Fluid ◽  
Life Saving ◽  
Life Threatening ◽  
History Of

Background. Uterine fibroids are common benign tumors in women. Clinical manifestations are well known. Acute complications necessitating emergent surgical intervention are rare. Case. We report a case of a 53-year-old woman with a history of uterine fibroids presenting with acute-onset severe abdominal pain. Imaging indicated massive free fluid and a large partially solid uterine mass. Vitals were consistent with hypovolemic shock. Examination revealed a surgical abdomen. She underwent an emergent laparotomy and total hysterectomy. Surgery revealed 4.5 L of hemoperitoneum and a 15 cm degenerated uterine fibroid with active bleeding. Pathology was consistent with intraoperative findings. She required transfusion of numerous blood products perioperatively. Her postoperative course was uncomplicated. Conclusion. It is rare for a uterine fibroid to spontaneously rupture. However, prompt recognition of this severe complication is critical for expeditious, life-saving surgical management.

Clinical-anamnestic analysis of the course and treatment of benign and borderline epithelial ovarian tumors

2016 ◽  
pp. 86-93
Author(s):  
M.Yu. Yegorov ◽  
◽  
A.A. Sukhanova ◽  
Keyword(s):  
Varicose Veins ◽  
Clinical Manifestations ◽  
Abnormal Uterine Bleeding ◽  
Abdominal Distension ◽  
Ovarian Tumors ◽  
Lower Limbs ◽  
Benign Tumors ◽  
Age Group ◽  
Venous Disorders ◽  
Serous Tumors

The objective: study the features of gynecological, physical history, diagnosis and treatment of patients with benign epithelial ovarian tumors (BeEOT) and borderline epithelial ovarian tumors (BEOT), determining the frequency of recurrence of ovarian tumors in the postoperative period. Patients and methods. According to a retrospective analysis of case histories of 112 women with epithelial ovarian tumors (EOT) underwent conservative or radical surgical treatment in a hospital, two groups were formed: I group – patients with benign epithelial ovarian tumors (BeEOT), which amounted to 85 (75.9%) women, and group II – patients with borderline epithelial ovarian tumors (BEOT), which amounted to 27 (24.1%) women. It was found that the main complaints of patients with EOT were pain (49.1%), abdominal distension (17%), and abnormal uterine bleeding (12.5%). The highest incidence of BeEOT (31.8%) observed in the age group of 41–50 years, while the peak incidence of BEOT (44.4%) corresponds to the age group of 51–60 years. Results. In BEOT endocrine pathology occurs significantly more frequently (p<0.05) than in BeEOT – 25.9% vs. 9.4%, respectively. Pathology of pancreatic-hepatobiliary system occurs significantly more frequently (p<0.05) in patients with BEOT compared with BeEOT – 81.5% versus 57.6%, respectively. Venous disorders (varicose veins of the pelvic organs, lower limbs, haemorrhoids) observed in BEOT significantly more frequently (p<0.05) than in BeEOT – 18.5% vs. 5.9%, respectively. EOT most often diagnosed in the period from 1 to 6 months after the first clinical manifestations with an average uptake of medical care 4.6±0.57 months. In assessing of peritoneal exudate cytogram the mesothelium cells are significantly more common for BeEOT (p<0.01) than BEOT – 79.4% versus 40.9%, respectively. Cervicitis is more likely significantly to occur in BeEOT (p<0.01) than in BEOT – 29.4% vs. 7.4%, respectively. The most common histological type among the benign tumors of the ovaries are endometriomas, which occurred in 48.2% of all BeEOT cases, and among the borderline tumors – serous tumors, which accounted for 59.3% of all BEOTs. Conclusion. The use of organ sparing surgery in EOT increases the risk of recurrence, especially in the case of endometrial histology or borderline variant of tumor. Key words: benign and borderline epithelial ovarian tumors, clinical-anamnestic analysis, diagnosis, treatment.

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