scholarly journals EFFECT OF POLYHERBAL FORMULATION IN SHEETAPITTA (URTICARIA): A CASE STUDY

2021 ◽  
Vol 9 (12) ◽  
pp. 3174-3178
Author(s):  
Verma Neeharika ◽  
Verma Keerti
Keyword(s):  
Lower Limb ◽  
Marked Improvement ◽  
Burning Sensation ◽  
The Body ◽  
Upper Respiratory Tract ◽  
Common Condition ◽  
Polyherbal Formulation ◽  
Causative Factors ◽  
Upper Respiratory

Aim: Urticaria is a common condition in children for which Paediatricians are consulted. In Ayurveda, it can be correlated with Sheetapitta which is a Tridoshaja vyadhi. The present study is aimed to show the effect of Polyherbal formulation in Sheetapitta (Urticaria) in children. Background: Urticaria is defined as a transient eruption of cir- cumscribed oedematous and usually itchy swellings of the dermis. As per Ayurveda, Urticaria can be correlated with Sheetapitta in terms of clinic features, causative factors and pathogenesis. Case Description: A 14-year-old female patient with her mother from Haridwar district came in OPD of Department of Kaumarbhritya, Rishikul Campus, Uttarakhand Ayurved University, Haridwar with the presenting complaints of red rashes all over the body along with itching, burning sensation and swelling since 2 years also having associated complaints like nasal con- gestion, sneezing and swelling B/L eyes from 2 months. On examining upper respiratory tract left-sided nasal hy- pertrophy, chapped lips, white-coated tongue, rt. sided slightly enlarged tonsils were found. On examining the In- tegumentary system, maculopapular lesions were present mainly over the upper limb, lower limb, chest and back. Swelling underneath B/L eyes was also present. The effect of the treatment was assessed on the basis of relief in itching and clearance of lesions. Conclusion: After the intervention of the polyherbal formulation for 45 days, there was a marked improvement in symptoms like Kandu, Vidaha and Shotha etc. So, it was concluded that internal use of Polyherbal formulation along with external use of Anu taila and the local application of Urtiplex lotion is highly effective in the management of Sheetapitta (Urticaria). Keywords: Urticaria, Sheetapitta, Kandu, Allergic disease

scholarly journals Modern possibilities of herbal medicine in the treatment of acute inflammatory diseases of the upper respiratory tract

2021 ◽  
pp. 127-133
Author(s):  
A. V. Gurov ◽  
A. V. Muzhichkova
Keyword(s):  
Phenolic Compounds ◽  
Respiratory Tract ◽  
Inflammatory Diseases ◽  
The Body ◽  
Upper Respiratory Tract ◽  
Plant Materials ◽  
Pelargonium Sidoides ◽  
Medicinal Substances ◽  
Upper Respiratory ◽  
Tract Infections

The article provides data on the effectiveness of the use of the drug in the treatment of acute, chronic and recurrent diseases of the respiratory tract and ENT organs. The drug is an extract of Pelargonium sidoides. From the standpoint of modern pharmacology, it is known that the use of natural products based on plant materials ensures safety and the absence of pronounced side effects. The main active ingredients of pelargonium are phenolic compounds: coumarins, flavonoids and phenolic acids. The article details the biochemical and pharmacological properties of each of the above groups of compounds. It has been shown that the presence of several classes of phenolic compounds simultaneously contributes to the potentiation of the pharmacological effects of each group separately. Therefore, drug has a pronounced polytropic effect: antiviral, antibacterial, immunomodulatory, mucolytic, anti-inflammatory, antioxidant, cytoprotective. The article presents the results of numerous domestic and foreign randomized, placebo-controlled studies demonstrating its high efficacy and safety in the treatment of ENT diseases, upper respiratory tract infections and bronchitis, not only in adults, but also in children over 1 year old. On the basis of the analyzed and presented material, the authors concluded that the use of a natural-based drug in the treatment of acute respiratory infection is effective and safe, both as monotherapy and in combination with other medicinal substances. He is able to quickly eliminate not only the symptoms of inflammation, but also to support the body with any ailments of this type.

scholarly journals Outdoor Activity: Benefits and Risks to Recreational Runners during the COVID-19 Pandemic

2021 ◽  
Author(s):  
Aswar Makruf ◽  
Doni Hikmat Ramdhan
Keyword(s):  
Physical Activity ◽  
Immune System ◽  
Respiratory Tract ◽  
Physiological Stress ◽  
Physical Distance ◽  
The Body ◽  
Upper Respiratory Tract ◽  
Strenuous Activity ◽  
Open Window ◽  
Upper Respiratory

Running has become one of the most popular recreational sports worldwide. It is an easily accessible form of exercise as there are minimal equipment and sport structure requirements. Aerodynamic simulation experiments showed a risk of droplet exposure between runners when two people run in a straight line at a close distance (slipstream). Thus, running activities require a safe physical distance of 10 meters to avoid droplet exposure, which can be a source of transmission of COVID-19 infection. However, running outdoors during the COVID-19 pandemic is still often done in pairs and even in groups without wearing a mask. Open window theory stated that changes in the immune system occur immediately after strenuous physical activity. Many immune system components showed adverse changes after prolonged strenuous activity lasting more than 90 minutes. These changes occurred in several parts of the body, such as the skin, upper respiratory tract, lungs, blood, and muscles. Most of these changes reflected physiological stress and immunosuppression. It is thought that an “open window” of the compromised immune system occurs in the 3–72-hour period after vigorous physical exercise, where viruses and bacteria can gain a foothold, increasing the risk of infection, particularly in the upper respiratory tract. Outdoor physical activity positively affects psychological, physiological, biochemical health parameters, and social relationships. However, this activity requires clear rules so that the obtained benefits can be more significant while simultaneously minimizing the risk of transmission of COVID-19 infection.

scholarly journals CoViD-19: An early intervention therapeutic strategy to prevent developing a severe disease as an alternative approach to control the pandemic

2020 ◽  
Author(s):  
HAMID MERCHANT
Keyword(s):  
Early Intervention ◽  
Respiratory Tract ◽  
Therapeutic Strategy ◽  
Wide Spectrum ◽  
Severe Disease ◽  
Antimicrobial Properties ◽  
The Body ◽  
Upper Respiratory Tract ◽  
Holistic Treatment ◽  
Upper Respiratory

While we wait for a confirmed drug or a vaccine for CoViD-19, it may be possible to intervene early to prevent the virus causing a severe disease to offer an alternative therapeutic strategy to control the pandemic. The global burden of CoViD-19 on the healthcare system can be significantly reduced by targeting CoViD-19 patients with or without symptoms who are self-isolating at home or in quarantine. If any therapeutic support can be offered to this group of patients that could attenuate the virus within the upper respiratory tract during the early stages of CoViD-19, it can give the body the time to produce enough antibodies to recover naturally from the disease before progressing into severe disease. An early intervention can, therefore, prevent the virus to get down the lower respiratory tract, reduce the number of cases with severe disease involving pneumonia and the need for hospitalisation. This article presents a simple yet holistic treatment strategy that involves inhaling steam supplemented with essential oils possessing wide spectrum antimicrobial properties in conjunction with oropharyngeal sanitisation to all those who are CoViD-19 positive or are under self-isolation due to symptoms. The approach is very simple, cheap, and effective in relieving the symptoms of the disease and is likely to reduce the viral load in the upper respiratory tract that may help recover from the infection. Since there is no vaccine or treatment yet approved to prevent or treat the CoViD-19, the importance of early intervention is invaluable in reducing the global disease burden. In the authors opinion, this strategy may be very effective to nip the infection in the bud before it gets difficult to treat and therefore, have a potential to significantly reduce the CoViD-19 associated hospitalisation.

scholarly journals ROLE OF BILWADI AGADA IN PREVENTION OF COVID - 19

2020 ◽  
Vol 8 (7) ◽  
pp. 3939-3944
Author(s):  
Varun Rajpuria ◽  
Anitta James
Keyword(s):  
Prevention And Control ◽  
Distress Syndrome ◽  
The Body ◽  
Ayurvedic Medicine ◽  
Pharmacological Properties ◽  
Upper Respiratory Tract ◽  
Corona Virus ◽  
Upper Respiratory ◽  
And Control

Agada Tantra is a specialized branch of Ayurveda which mainly deals with Visha (Poison) and its management mainly through special formulations called Agada Yogas which counteract the deleterious actions of poison over the body. There are numerous such formulations which are unique because of their potent ingredients and fast action. Bilwadi Agada is one among such Yogas. In December 2019, a series of acute atypical respiratory disease occurred in Wuhan and then rapidly spread to other areas. It was soon discovered that a novel Corona Virus was responsible, and this was named as the Severe Acute Respiratory Syndrome Corona Virus-2 (2019) due to its high homology to SARS-CoV-2 which caused Acute Respiratory Distress Syndrome and high mortality during 2002–2003 in China. According to Ayurveda, this novel Corona is a Jangama Visha as it is of zoonotic origin. It affects the upper respiratory tract so is the movement of Jangama Visha which moves upward and affects those areas. It is also mentioned in Ayurvedic treatise that the Jangaman Visha should be treated with Sthavara dravyas. Bilwadi gutika is an Ayurvedic medicine prepared from thirteen medicinal plants triturated in goat’s urine. When we compare the primary symptoms of COVID-19 and the indications of Bilwadi gutika, we can see so many similarities. The main objective of this article is to discuss the therapeutic and pharmacological properties of Bilwadi Agada and thereby understanding its role in prevention and control of COVID-19 pandemic.

Chemoprophylactics

2018 ◽  
pp. 289-304
Author(s):  
Clapperton Chakanetsa Mavhunga
Keyword(s):  
Drug Resistance ◽  
Ultraviolet Radiation ◽  
Clinical Condition ◽  
Burning Sensation ◽  
The Body ◽  
Historical Overview ◽  
Southern Rhodesia

Chemoprophylaxis refers to the administration of medication to prevent disease or infection. This chapter first gives a historical overview of chemoprophylaxis in Southern Rhodesia, then turns to the problem of drug resistance and photosensitization, which is a clinical condition in which the skin's negative exposure and reaction to sunlight is heightened due to phototoxic drugs and chemicals. This photosensitivity occurs when these substances absorb sunlight (ultraviolet radiation), triggering a burning sensation, redness, and swelling. The chapter ends with a case study of chemoprophylaxis operations in Southern Rhodesia, exploring how the early promises of chemoprophylaxis ended with unforeseen complications that poisoned instead of cured animals of n'gana. The argument made is one about pollution of the most intimate kind: within the body, both of the animal and hutachiwana itself.

Fatal Outcomes from COVID-19 in Diabetes Patients and its Management: Impact of Diabetes and Other Comorbidities on COVID-19

2021 ◽  
Vol 17 ◽  
Author(s):  
Suruchi Singh ◽  
Pankaj Bhatt ◽  
Satish Kumar Sharma ◽  
Tejinder Kaur
Keyword(s):  
Risk Factor ◽  
Severe Acute Respiratory Syndrome ◽  
Severe Pneumonia ◽  
Cardiovascular Disorder ◽  
The Body ◽  
Upper Respiratory Tract ◽  
Inflammatory Cardiomyopathy ◽  
Cardiovascular Comorbidity ◽  
Upper Respiratory ◽  
Body Response

: Many studies have approved that COVID-19 disease was caused by Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), severe acute respiratory syndrome coronavirus-1(SARS-CoV-1), and has spread as an epidemic from across the world today. Initially, it affects the upper respiratory tract, induces viral infection in the lungs, and causes severe pneumonia in the COVID-19 infected patients. After the infection in the body, changes appear in other biomarkers in the body therby imbalancing the body response studied by the virus's pathophysiology. However, this infection starts comorbidity directly and indirectly in COVID-19 infected patients. During this period of infection, the immune system is also suppressed by the virus and initiates other diseases. The authors focus on the cardiovascular comorbidity study of COVID-19 in the current work. In the comorbidity study of COVID-19, the virus mainly affects hypertension patients. The risk factor of comorbidity of hypertension and cardiovascular disorder is 30.7%, and 11.9% with diabetes mellitus. In this study, we reveal the pathophysiology, treatment, and management of cardiovascular diseases, their risk factor, and medicine results on the COVID-19 infected patients. SARS-CoV-2 primarily targets ACE-2 receptors because this virus receives this receptor as a host for the cellular entry of the virus in the body, these shows down regulations in the maintenance of BP, and the body suffers from multi-organ failure. The other diseases related to CVS are Inflammatory cardiomyopathy, congestive heart failure, irregular heartbeat, embolism events, and Coronary infarction that also affect its pathophysiology.

scholarly journals Comparative analysis of medical and statistical indicators of morbidity in the military serving under contract in the Navy and Land Forces of Russia (2003–2018)

2019 ◽  
pp. 35-62 ◽  
Author(s):  
V. I. Evdokimov ◽  
P. P. Sivashchenko
Keyword(s):  
Military Personnel ◽  
Head Injuries ◽  
Armed Forces ◽  
The Body ◽  
Upper Respiratory Tract ◽  
State Of Health ◽  
Acute Infections ◽  
Icd 10 ◽  
Upper Respiratory ◽  
The Military

Relevance. When solving military-professional tasks during the period of reforming the Armed Forces of Russia, military servicemen under contract (sergeants, foremen, privates and sailors) are given a special role, and in a number of units they must replace conscripts.Intention To analize medical and statistical morbidity indicators of military personnel under contract in the Navy and the Land Forces of Russia.Methods. We studied medical reports on the state of health of personnel and medical service activity according to Form 3 / MED of military units, in which about 60% of the total number of servicemen of the Russian Armed Forces served from 2003 to 2018. Morbidity indicators were correlated with the International statistical classification of diseases and related health problems, 10th revision (ICD-10).Results and Discussion. As a rule, the military personnel under contract in the Russian Navy had lower morbidity rates with high dismissal rates. In particular, the indicators were as follows: the average annual overall morbidity rates were (855.0 ± 65.3) and (946.9 ± 49.7) ‰ in the military personnel under contract in the Russian Navy and in the Land Forces of Russia, respectively; primary incidence, (384.8 ± 19.3) and (472.0 ± 22.8) ‰, respectively (p < 0.01); need for follow-up, (92.8 ± 9.9) and (74.3 ± 4.7) ‰, respectively; hospital admission rates, (205.8 ± 39.2) and (235.2 ± 13.2) ‰, respectively; working days lost, (4,038 ± 203) and (3.944 ± 196) ‰, respectively; dismissal rates, (6.82 ± 0.57) and (4.40 ± 0.61) ‰, respectively (p < 0.01); mortality rates, (112.13 ± 9.91) and (111.76 ± 7.80) per 100,000 military personnel under contract. It is possible that this phenomenon was determined by the peculiarities of professional activity, the organization of medical support and the high demands placed on the state of health of the Russian Navy servicemen. A significant part of the leading disease blocks with a share of 0.5% or more in the structure of medical and statistical morbidity indicators, were similar between the military personnel under contract in the Navy of Russia and the Land Forces of Russia. In the structure of the assessed military-epidemiological significance of disease blocks among the military personnel under contract of the Russian Navy, acute infections of the upper respiratory tract (J00– 06 by ICD-10) ranked 1st, diseases of the esophagus, stomach and duodenum (K20–K31) ranked 2nd, followed by injuries involving several areas of the body (T08–T14), head injuries (S00–S09), ischemic heart disease (I20–I25). In the military personnel under contract in the Land Forces of Russia, these were the following diseases, from the most to least significant: acute infections of the upper respiratory tract (J00–J06), injuries involving several areas of the body (T08–T14), head injuries (S00–S09), diseases of the esophagus, stomach and duodenum (K20–K31), and infections of the skin and subcutaneous tissue (L00–L08).Conclusion. Prevention of the leading groups of disaeses will contribute to improving the health status of servicemen under contract, and taking data on morbidity into account will help organize diagnostic and treatment assistance and optimize the personnel and material resources of military medical organizations. 

scholarly journals Investigation of the relationship between fractal and hydraulic properties of porous structures of the upper respiratory tract of some Arctic animals

2020 ◽  
Keyword(s):  
Respiratory Tract ◽  
Hydraulic Resistance ◽  
Fractal Dimensions ◽  
The Body ◽  
The Arctic ◽  
Porous Structures ◽  
Upper Respiratory Tract ◽  
Fractal Structures ◽  
Adequate Model ◽  
Upper Respiratory

The respiratory ducts of animals and humans are presented by curved tubes with complex geometries. The open areas in such structures are filled with moving air governed by a pressure drop between the inlet and outlet of the duct. The complex structures formed by thin walls and warmed by constant blood flow at the body temperatures T=36-39 C serve for fast and efficient warming of the inhaled air to the body temperature and its moistening up to 100% humidity. The Arctic animals possess the most efficient nasal ducts allowing the heating of the inhaled air from T=-30-60C to T=38-39 C during the duct with the length L=8-15 only. The detailed geometry of the nasal ducts of some Arctic animal has been studied on the computed tomograms (CT) scans of the heads of the animals found in the open databases and published in literature. The highly porous structures on some slices are formed by fractal-like divisions of the walls protruded into the nasal lumen. Since the fractal structures are characterized by their fractal dimensions D, the relationships between the hydrodynamic properties and fractal dimensions of the porous structures of the upper respiratory tract of some Arctic animals has been studied. The dimensions D of the cross sections of the tract have been calculated by the counting box method. The porosities of the samples, the tortuosity of the pores, and the equivalent hydraulic diameter Dh of the channel have been calculated. Sierpinski fractals of various types have been used as models of porous structures, for which the above listed parameters, as well as hydraulic resistance to a stationary flow, have also been computed. A number of statistical dependencies between the calculated parameters were revealed, but the absence of their correlations with D was shown. It was obtained, the structures with different porosities and hydraulic resistance Dh can have the same values ​​of D. Therefore, the choice of an adequate model based on only D value introduces significant errors in the calculations of air heating along the upper respiratory tract. The statistical dependences inherent in the natural samples studied can be obtained only on the basis of multifractal models in which the number and shape of the channels, as well as the scale of their decrease, change in a certain way at each generation.

scholarly journals HEMATOLOGICAL AND BACTERIOLOGICAL PREDICTORS OF OCCUPATIONALLY AND INDUSTRIAL CONDITIONED DISEASES IN MEDICAL WORKERS

2020 ◽  
Vol 99 (1) ◽  
pp. 125-128
Author(s):  
L. M. Karamova ◽  
Natalya V. Vlasova ◽  
L. G. Gizatullina ◽  
L. M. Masyagutova
Keyword(s):  
Respiratory Tract ◽  
Allergic Diseases ◽  
The Body ◽  
Hospital Environment ◽  
Upper Respiratory Tract ◽  
Hemoglobin Content ◽  
Hematological Indices ◽  
Mucous Membranes ◽  
Upper Respiratory ◽  
Medical Examinations

Introduction. Medical workers in the process of labor are exposed to a complex of adverse factors: neuro-emotional, physical stress of a chemical, physical and biological nature. A long stay in a hospital environment with medical workers can lead to the formation of various diseases of microbiological etiology or the carriage of pathogenic and conditionally pathogenic flora and the development of dysbiosis. Objective. Give hematological and bacteriological characteristics of the health status of medical workers. Material and methods. The results of laboratory studies of blood and mucous membranes of the upper respiratory tract of medical workers performed during the performing occupational medical examinations are analyzed. Results. Hematological indices were found to be characterized by an increased hemoglobin content in one-fourth of the examined workers, as well as lymphocytosis, eosinophilia, cholesterolemia. The microflora of the mucosa of the upper respiratory tract is mainly represented by Staphylococcus aureus, Candida albicans, Streptococcus pyogenes in 65.2% of the workers; the remaining 34.8% were revealed to have a resident microflora. With the experience of work, the frequency of insemination increases and doubles by 10 years of the work. The structure of microflora is also changing. In the nosological form of occupational morbidity, allergic diseases prevail and account for 60.8%, tuberculosis - 26.0%, and hepatitis - 8,6%. Conclusion. All these changes in the body are the basis of pathogenetic manifestations in the formation of allergic and pathogenic pathologies, which make up to 70.0% of all occupational morbidity.

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