scholarly journals The Effectiveness of Goksuradi Guggulu and Varunadi Kwath with Goksuradi Guggulu in the Management of Mutrasmari w.s.r. to Urolithiasis

2021 ◽  
pp. 463-469
Author(s):  
Sabbu Thasineku ◽  
Binod Kumar Singh ◽  
D.L.Bharkher ◽  
Sirjana Shrestha ◽  
Raj Kishor Shah ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Lifestyle Modification ◽  
Renal Calculus ◽  
Dietary Regimen ◽  
Treatment Groups ◽  
Mild Improvement ◽  
Before And After ◽  
Group A ◽  
Group B ◽  
Lottery System

Introduction: Mutrasmari is considered as Astamahagada in Ayurveda in which there is formation of stone in the Mutravaha srota. It is an ancient disease with global distribution. The symptoms of Mutrasmari are excruciating pain in urethra, ureter, urinary bladder and over umbilical region, haematuria etc and later that may lead to emergence by the obstruction in urination. Hence on the basis of pathology and its clinical presentation the disease is correlated with Renal calculus or Urolithiasis in modern Urology. Methodology: 38 patients diagnosed as Mutrasmari were randomly divided in two groups as per the lottery system of randomization. The patients of Group A were given 1000mg Goksuradi guggulu twice a day for 45 days. The patients of Group B were given 1000 mg of Gokshuradi guggulu along with 45 ml of Varunadi kwatha twice a day for 45 days. The patients of both the groups were advised to follow the dietary regimen and lifestyle modification. The effect of the intervention was assessed before and after treatment. Result: The treatment outcomes were statically analyzed and found that both treatment groups were significant in relieving the symptoms like abdominal pain, burning micturition, dysuria and expulsion of renal culculi. 100% relief  noted on Surudhir mutrata (Hematuria) where only single patient complaint had been registered as Hematuria in Group B. In case of Mutradaha (Burning micturation) there was mild improvement in group A and moderate improvement in group B. Similarly there was complete remission in Mahati vedana (Dysuria and Pain in abdomen) case in both Group A and Group B after the treatment. Conclusion: Gokshuradi guggulu along with Varunadi Kwatha shows more significant result than Gokshuradi guggulu.

scholarly journals A Comparative Clinical Study of Trikarshika Kwatha with and without Lifestyle Modification in the Management of Vatarakta with Special Reference to Hyperuricaemia

2021 ◽  
pp. 10-19
Author(s):  
Md Tanzil Ansari ◽  
Sukumar Ghosh ◽  
Shailendra Kumar Singh
Keyword(s):  
Clinical Study ◽  
Lifestyle Modification ◽  
Test Results ◽  
Before And After ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B ◽  
High Level ◽  
Urate Crystals

Nowadays, people are more vulnerable to metabolic disorders due to their faulty dietary and behavioural habits. One such disorder is Vatarakta which causes functional impairment due to involvement of Sandhi (joints). It is manifested by Ruk, Toda, Sparsha asahatva, Shopha, Raga, Daha and Stabdhata in Sandhi. Vatarakta can be correlated with Hyperuricaemia or Gout due to similarity in their clinical features. Hyperuricaemia is defined as abnormally high level of uric acid in blood (i.e. >6mg/dl in female and >7mg/dl in male). On the other hand, Gout is an inflammatory response to monosodium urate crystals formed secondary to hyperuricaemia. Aims and objectives: 1. To evaluate the effectiveness of Trikarshika kwatha and lifestyle modification in the management of Vatarakta. 2. To compare the effects of Trikarshika kwatha with and without lifestyle modification in the management of Vatarakta. Materials and methods: Raw herbs of the research formulation were collected after proper identification and Kwatha was prepared for oral administration. For the clinical study, total 60 patients were selected on the basis of selection criteria. Selected patients were randomly divided into two groups. (i) Group A: 30 patients were treated with Trikarshika kwatha. (ii) Group B: 30 patients were treated with Trikarshika kwatha along with Lifestyle modification. Individual patient was treated for 45 days along with follow up at the interval of every 15 days. To assess the effectiveness of treatment, scoring pattern was followed for subjective and objective parameters. They were assessed before and after treatment. The collected data were analysed statistically by using Paired t-test. Results: On the basis of all statistical data, it can be said that patients of Group B showed better results in all parameters in comparison to patients of Group A. Conclusion: Both Trikarshika kwatha and Lifestyle modification are affective but Trikarshika kwatha with Lifestyle modification is more effective than Trikarshika kwatha without Lifestyle modification in the management of Vatarakta.

scholarly journals The Effectiveness of Taalishadi Churna Compared with Sitopaladi Churna in the Management of Kasa

2021 ◽  
pp. 463-470
Author(s):  
Sirjana Shrestha ◽  
Shankar Gautam ◽  
Sabbu Thasineku ◽  
Jitendra Shrestha ◽  
D.L. Bharkher ◽  
...  
Keyword(s):  
Neutrophil Count ◽  
Clinical Presentation ◽  
Treatment Time ◽  
Blood Parameters ◽  
The Other ◽  
Health Statistics ◽  
Group A ◽  
Pre Treatment ◽  
Group B ◽  
Lottery System

Introduction: Kasa is a Vata-kapha pradhana disease, caused due to Vata vimargagaman and Pranavaha shrotodusti. Due to the various similarities in its clinical presentation, Kasa can be correlated with cough (bronchitis). According to National center for health statistics, 62 million cases of common cold and cough occurs each year. Methodology: A total of 44 patients diagnosed as Kasa were randomly divided as per the lottery system of randomization. The patients of Group A were given 5 gram of Sitopaladi Churna twice a day for 30 days. The patients of Group B were given 5 gram of Taalishadi Churna twice a day for 30 days. The patients of both the groups were supposed to follow the dietary and behavioural advices. The response of the drug was assessed at pre-treatment and post-treatment time. Results: There was equal significant change in all of the Roga bala, Agni bala and Deha bala parameters by both Sitopaladi and Taalishadi Churna. It was revealed that all other blood parameters except Hb, TLC and Neutrophil count used in the study were not significant in both the groups. Both drugs were found equally highly significant (p< 0.0001) in Sushka kasa and Swarabheda. Sitopaladi churna was more effective in relieving Hritparswashool (p=0.002) whereas Taalishadi churna is more effective in reducing Pitanisthivanam (p=0.007). In case of Nirghosh, Sitopaladi churna was more effective (p<0.0001). On the other hand, Taalishadi churna was more effective in relieving Peenasa (p<0.001). Conclusion: Both Sitopaladi Churna and Taalishadi Churna were found to be equally effective in the treatment of Kasa.

scholarly journals Study of the Efficacy of Ksharaplota in Dushtavrana w.s.r to Infected Wound

2020 ◽  
Vol 11 (2) ◽  
pp. 314-321
Author(s):  
Anantkumar V Shekokar ◽  
Vijay P Ukhalkar
Keyword(s):  
Clinical Presentation ◽  
Healing Time ◽  
Control Group ◽  
Infected Wound ◽  
Group Assessment ◽  
Before And After ◽  
Group A ◽  
Level Of Significance ◽  
Group B ◽  
Vast Range

Vrana ( wound and ulcer) & process of healing is the soul of Shalyatantra Chikitsa (Surgical treatment ). Dushta Vrana means getting vitiated by Dosha & hence Dushta Vrana or infected wound is characterized by bad smell, abnormal color with profuse discharge, severe pain and longer healing time. The severity of infected wounds and their vast range of etiologies, The treatment is cleaning & dressing the wound or it can be more extensive. It may require surgical intervention to close the wound and stabilize the patient. Acharya Sushruta defines Kshara as the substance possessing Ksharana and Kshanan properties. Ksharaplota formulation was selected and applied over the affected infected wound with the help of gauze piece. During the preparation of Ksharaplota, it is coated with Snuhi kshira, Apamarga kshara & Haridra. All these drugs are Shodhana & Ropana. It was observed that Ksharaplota has the properties as sustained release of drug, absorbs discharges, less painful & easily acceptable by the patient with excellent Sodhana & Ropana Karma. The clinical study has been done on 438 patients, selected randomly and divided in two groups. Group A 220 patients i.e. trial group, were treated with local application of Ksharaplota. The Group B 218 patients i.e. control group, were treated with Gold standard. The clinical assessment was done on the basis of clinical presentation of Dushta Vrana, (Infected wound) before and after the treatment. As grading used for assessment of parameters which were ordinal in nature, “Wilcoxon Signed Ranks test” was used for within the group assessment (i.e. before and after treatment of a group). For between the group assessment of parameters, Mann Whitney – U test was applied. We had tested hypothesis for each parameter and result was interpreted accordingly. The level of significance was kept at 5% (P=0.05). And the result of the present study found significant.

scholarly journals COMPARATIVE STUDY ON THE EFFICACY OF MAITLAND TECHNIQUE (GRADE IV) AND MULLIGAN TECHNIQUE, IN THE TREATMENT OF FROZEN SHOULDER

2013 ◽  
Vol 2 (1) ◽  
pp. 10-14
Author(s):  
Syed Abid Mehdi Kazmi ◽  
Jharna Devi ◽  
Faisal Yamin ◽  
Sunil Kumar
Keyword(s):  
Experimental Study ◽  
Functional Activity ◽  
Frozen Shoulder ◽  
Group Interventions ◽  
Treatment Results ◽  
Treatment Groups ◽  
Before And After ◽  
Group A ◽  
Group B ◽  
Positive Results

OBJECTIVES To compare the effectiveness of Maitland technique (Grade IV) and Mulligan technique for the treatment of frozen shoulders. STUDY DESIGN Experimental Study. STUDY SETTINGS & PARTICIPANTS This study has been conducted at Ziauddin Hospital with 50 volunteers who participated in the study that were equally divided into two groups (pre and post treatment groups). Subjects were randomly assigned to each group. INTERVENTIONS Intervention given to Group A was Maitland Technique (Grade IV) and Group B, Mulligan Technique. OUTCOME MEASURES Functional activity of shoulder is measured by using Shoulder Pain and Disability Index (SPADI) score, Pain is measured by VAS Score, and Range of motion, measured by Goniometer both before and after treatment. RESULTS Both the treatments showed positive results but Mulligan technique was found to be more effective. The total SPADI score was 15.48 before and 11.92 after the Mulligan technique and 15.32 before and 13.16 after the Maitland technique. CONCLUSIONS It is evident that Mulligan technique is more effective for the treatment of frozen shoulder compared to Maitland technique.

scholarly journals Correlation of vitamin D level with its related biochemical parameters and impact of different treatment regimens on their correction

2020 ◽  
Vol 8 (1) ◽  
pp. 86
Author(s):  
Amit Gupta ◽  
Sachin Kumar
Keyword(s):  
Biochemical Parameters ◽  
Inverse Correlation ◽  
Ultraviolet Rays ◽  
P Value ◽  
Significant Inverse Correlation ◽  
Treatment Groups ◽  
Treatment Regimens ◽  
Before And After ◽  
Group A ◽  
Group B

Background: Vit D is a fat-soluble vitamin that is produced when ultraviolet rays from sunlight strike the skin and trigger vit D synthesis. Aims and Objectives of the study were to find out the correlation of vit D level with its related biochemical parameters and impact of two different treatment regimens on their correction. Methods: A total of 107 patients were followed up out of which 89 were vit D deficient and rest were vit D insufficient. Results: Mean age of the patients was 6.11±4.49 and males comprised 66%. Mean BMI of children included in group A, B and C was 19.40±2.69, 19.60±3.18 and 20.95±3.72 kg/m2 respectively. Vit D levels at baseline had a significant inverse correlation with ALP (r=-0.27, p value=0.008).  Before and after comparison of mean serum calcium levels revealed significant improvement in both the treatment groups. Severity of vit D deficiency, at baseline, 9.10, 77.30 and 13.60% of patients had vit D levels of less than 5, 5 to 15 and more than 15 for group A respectively. In group B at baseline, 6.70, 71.10 and 22.20% of patients had vit D levels of less than 5, 5 to 15 and more than 15 respectively.Conclusions: Present study found that 60,000 IU/week and dose of 2000 IU/day for infants or 5000 IU/day for 1 to 18 years of age, along with 500 to 800 mg oral calcium for 6 to 8 weeks can result in correction of vit D deficiency.

Study the Relationship Between Estrogen Hormone and Calcium in Normal Females Before and After Menopause in Baghdad / Iraq

2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Sameerah Mustafa ◽  
Asal Tawfeeq ◽  
Hadeel Hasan
Keyword(s):  
Oral Contraceptive ◽  
Healthy Controls ◽  
Serum Samples ◽  
Oral Contraceptive Pills ◽  
Contraceptive Pills ◽  
Menopausal Women ◽  
Before And After ◽  
Group A ◽  
Group B ◽  
Age Range

This study involved the collection of (90) samples of women serum which included (30) serum samples collected from women before menopause (reproductive women) in the age range of (22-43) years and were considered as (group A- control). While, (group B) included (30) serum samples collected from women using oral contraceptive pills between the ages of (22-43) years old. Whereas, another (30) serum samples were collected from women after menopause between the ages of (43-54) years and were considered as (group C). All of the collected serum samples were subjected to a number of serological and chemical tests for the measurement of (E2, HDL, LDL and Ca). Then, the obtained data were statistical analyzed and results showed a significant decrease (p˂ 0.05) in (E2 ,Ca and HDL) levels in menopausal women compared to that of the normal healthy controls. While, there were non-significant decrease (p> 0.05) in (E2, Ca and HDL) levels in women taking oral contraceptive when compared to the normal healthy controls. On the other hand, a significant increase (p˂ 0.05) was recorded in LDL level in menopausal women compared to that of the normal healthy controls whereas, no-significant increase (p˃ 0.05) in the LDL level in women taking oral contraceptives when compared to the control women.

A Comparative Study of Amalaki Choorna along with Madhu and Vata Twak Kashaya Yoni Pichu Dharana in the Management of Shweta Pradara

2017 ◽  
Vol 2 (4) ◽  
Author(s):  
Renuka M. Tenahalli
Keyword(s):  
Vitamin C ◽  
Early Stage ◽  
Pathological Condition ◽  
Before And After ◽  
Group A ◽  
Phosphorus Iron ◽  
Group B ◽  
Busy Schedule ◽  
Iron And Calcium

Shweta Pradara (Leucorrhoea) is the disease which is characterized by vaginal white discharge. Vaginal white discharge this symptom is present in both physiological and pathological condition, when it becomes pathological it disturbs routine life style of the woman. Most of the women in the early stage will not express the symptoms because of hesitation and their busy schedule. If it is not treated it may leads to chronic diseases like PID (Garbhashaya Shotha etc.) Charaka mentioned Amalaki Choorna along with Madhu and Vata Twak Kashaya Yoni Pichu Dharana. This treatment is used in Shweta Pradara shown positive results, hence a study was under taken to assess its clinical efficacy. 30 diagnosed patients of Shweta Pradara were randomly selected, allocated in three groups. Group A and Group B received Amalaki Choorna with Madhu and Vata Twak Kashaya Yoni Pichu Dharana respectively and Group C received Amalaki Choorna with Madhu followed by Vata Twak Kashaya Yoni Pichu Dharana for 15 days. The patients were assessed for the severity of the symptoms subjectively and objectively before and after the treatment and at the end of the follow up. Data from each group were statistically analyzed and were compared. No side effects were noted and it may be considered as an effective alternative medicine in Shweta Pradara (leucorrhea). Amalaki is rich in natural source of vitamin C and contains phosphorus, iron and calcium. Honey contains carbohydrate, vitamin C, phosphorus iron and calcium. All together these help to increase Hb% and immunity. Vata Twak Kashaya contains tannin which helps to maintain normal pH of the vagina.

Survival of classic swine fever virus in hams made from the meat of pigs vaccinated with the PAV-250 strain and unvaccinated pigs

2019 ◽  
Vol 10 (3) ◽  
pp. 536-551
Author(s):  
Heidi Amezcua Hempel ◽  
María Salud Rubio Lozano ◽  
Eliseo Manuel Hernández Baumgarten ◽  
Pablo Correa Girón † ◽  
Oscar Torres Ángeles ◽  
...  
Keyword(s):  
Reference Strain ◽  
Clinical Signs ◽  
Classical Swine Fever ◽  
Fever Virus ◽  
Direct Immunofluorescence ◽  
Biometric Analysis ◽  
Treatment Groups ◽  
Group A ◽  
Group B ◽  
Group D

The study was to determine the presence of Classical Swine Fever virus (CSFv), in the meat of vaccinated pigs with the PAV-250 strain and then challenged using the same strain. Five treatment groups were established (each with four pigs). Group A: Pigs thatwere fed with processed hams from negative animals; Group B: Pigs that were fed with processed hams from commercial pigs inoculated with the ALD (reference strain) (titre of 104.0/ml); Group C: Pigs fed with processed hams from pigs infected with the virulent ALD strain (titre of 102.5/ml); Group D: Pigs fed with processed hams from pigs vaccinated with the PAV-250 strain and challenged with the ALD strain (titre of 101.1/ml); and Group E: Pigs fed with processed hams from pigs vaccinated with two doses of the PAV-250 strain and challenged with the ALD strain (negative). Blood samples were taken at d 1, 5, 10, 15 and 20 for biometric analysis. Groups B, C and D manifested clinical signs of CSFv: 40 °C temperature, anorexia, paralysis, vomiting, diarrhea, tremor, hirsute hair and cyanosis. Pigs were slaughtered and necropsies performed to identify lesions in tissues. Results of direct immunofluorescence testing of tissues were positive and the virus was recovered. Under these study conditions, it was found that CSFv resisted the cooking method at 68 °C for 40 min in hams from unvaccinated pigs, and that the virus was able to transmit the disease to healthy unvaccinated pigs, whereas the hams from the vaccinated animals did not transmit the virus.

scholarly journals Application and practice of a step-by-step method combined with case-based learning in Chinese otoendoscopy education

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Fanqin Wei ◽  
Qiyang Sun ◽  
Zili Qin ◽  
Huiwen Zhuang ◽  
Guangli Jiang ◽  
...  
Keyword(s):  
Learning Experience ◽  
Step Method ◽  
Innovative Methods ◽  
Before And After ◽  
Case Based Learning ◽  
Group A ◽  
Clinical Thinking ◽  
Group B ◽  
Learning Interest ◽  
Case Based

Abstract Background Standardized training allows more physicians to master otoendoscopic surgery. However, the lecture-based learning (LBL) applied in otoendoscopy teaching may not be conducive to training students in clinical thinking and surgical ability. It is necessary to explore innovative methods for otoendoscopy teaching. This study aimed to determine the effect of a step-by-step (SBS) method combined with case-based learning (CBL) in otoendoscopy teaching. Methods Fifty-nine physicians who participated in otoendoscopy training were selected as the study subjects and randomly divided into two groups (A and B). Group A underwent training with the SBS & CBL method, while Group B underwent training with the LBL & CBL method. The effects of these two methods for otoendoscopy training were compared by evaluation of professional skills and questionnaires before and after the training. Results Proficiency in otoendoscopic anatomy and grades for both professional knowledge and otoendoscopic skills were significantly higher in Group A than in Group B(P < 0.05). In terms of learning interest, surgical ability, acting capacity during surgery, reducing surgical complications, and satisfaction with learning experience, all responses from Group A were better than those from Group B(P < 0.05). Conclusions The SBS & CBL method may help to improve ability in otoendoscopic surgery and clinical thinking and appears suitable for endoscopy teaching.

Comparison of montelukast and mometasone furoate in the prevention of recurrent nasal polyps

2011 ◽  
Vol 6 (1) ◽  
pp. 5-10 ◽  
Author(s):  
Erkan Vuralkan ◽  
Cem Saka ◽  
Istemihan Akin ◽  
Sema Hucumenoglu ◽  
Binnur Uzmez Unal ◽  
...  
Keyword(s):  
Recurrence Rate ◽  
Nasal Spray ◽  
Peripheral Blood ◽  
Nasal Polyposis ◽  
Mometasone Furoate ◽  
Significant Difference ◽  
Before And After ◽  
Group A ◽  
Group B ◽  
Snot 22

Background: The aim of our study was to compare the effects of montelukast and mometasone furoate nasal spray on the postoperative course of patients with nasal polyposis. Patients and methods: Fifty patients diagnosed with nasal polyposis between March 2006 and August 2007 were included in the study. All patients underwent bilateral endoscopic sphenoethmoidectomy and were randomized postoperatively into two groups. Group A ( n = 25) received 10 mg montelukast per day and group B ( n = 25) received 400 µg mometasone furoate nasal spray twice daily. All patients were followed up for 6 months. Sino-Nasal Outcome Test (SNOT)-22 scores, polyp grades, computerized tomography (CT) scores (Lund–Mackay), eosinophils in peripheral blood and polyp tissue were evaluated before and after surgery. Results: There was a significant reduction in SNOT-22 scores in both groups throughout the study period. There was a significant difference in the recurrence rate between both groups with a marginal advantage of mometasone furoate nasal spray. Eosinophils in peripheral blood were found to be effective on the recurrence rate ( p < 0.05). Conclusions: In conclusion, both drugs seem to have a complementary action and further studies are needed to determine which patients should receive which treatment.

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