Bladder Condyloma Acuminatum, A Case Report

2020 ◽  
pp. 1-3
Author(s):  
Villalba Bachur Roberto ◽  
◽  
Spagnuolo Juan Ignacio ◽  
Cora Florencia ◽  
◽  
...  
Keyword(s):  
Cervical Carcinoma ◽  
Hpv Infection ◽  
Cancer Case ◽  
World Population ◽  
Single Episode ◽  
Papilloma Virus ◽  
High Incidence ◽  
Bladder Cancer Case ◽  
History Of ◽  
Laser Enucleation

Background: Human Papilloma virus (HPV) infection is a high incidence entity in the world population. It is highly related to cervical carcinoma, as well as anogenital carcinoma, among others. The presences of bladder HPV lesions are infrequent and there is an association between it and the development of bladder cancer. Case presentation: We present a case of bladder HPV in a woman with a cervical carcinoma history that was presented clinically as a single episode of gross hematuria. We performed a cystoscopy and Holmium laser enucleation of the bladder tumors. Conclusion: We highlight the importance of consider HPV as a differential diagnosis of a bladder tumor, mainly in patients with history of pathologies related with the virus.

scholarly journals Infeksi Chlamydia Trachomatis pada Penderita Karsinoma Serviks Terinfeksi Human Papilloma Virus (HPV) tipe 16 di RSUP Dr. Sardjito Yogyakarta

2010 ◽  
Vol 1 (1) ◽  
pp. 55
Author(s):  
Indri Ramayanti
Keyword(s):  
Developing Countries ◽  
Cervical Carcinoma ◽  
World Wide ◽  
Malignant Neoplasm ◽  
Hpv Infection ◽  
Radical Mechanism ◽  
Major Health Problem ◽  
Major Health ◽  
Papilloma Virus

Cervical carcinoma is one of the most common malignant neoplasm amongwomenin developing countries and remains as a major health problem world wide. In Indonesia,the incident of cervical carcinoma are around 180.000 new cases per year or 90-100 nevvcancers among 100.000 communities. Several studies have reported the role of HPV as anSTD agent (Sexually Trasmitted Disease). Cofactor in the HPV infection accelerate up thedevelopment of infection into cancer One of the STD cofactor is co infection with C.trachomatis. Infection ofC. trachomatis is perceived as cofoctor that synergatedwith HPVthroughfree radical mechanism and immune system.The objective of the study is to know the presence of C. trachomatis infection hadpotencyfor being cofactor HPV I 6 in cervical carcinoma patients.Twentylhree sample of cervical smeati cervical carcinoma biopsies and freshtissue obtained from surgerydep, from DR. Sardjito Hospital, Yogtalurta. The DNAisolated of samples were amplified by PCR using primer (E6for-vvard and reversed) fromORF E6 HPV I 6. Sample with positive DNA HPV I 6 was then ampli/ied C. trachomatis genus i ng p ri m er (C C 3 / C C Q from th e s e q uen c e of cry ptic C hl amy dia p I asmid.The research showed thatfrom 23 cases of cervical carcinomawere obtained HPVpositive type 16 with 16 cases (69,5%o). From 16 cases of HPV type 16 positive cervicalcarcinoma, 15 cases were examined to know the presence of C. trachomatis and wereobtained 8 cases (53,j%o) as C. trachomatis positive.

scholarly journals Verruca: Need to Know about Human Papilloma Virus (HPV) Infection

2012 ◽  
Vol 30 (3) ◽  
pp. 151-158 ◽  
Author(s):  
Lubna Khondker ◽  
Md Obaidur Rahman Shah ◽  
Md Shirajul Shirajul Islam Khan
Keyword(s):  
Human Papilloma Virus ◽  
Significant Proportion ◽  
Hpv Infection ◽  
Malignant Potential ◽  
Low Grade ◽  
High Grade ◽  
Cervical Lesions ◽  
Papilloma Virus ◽  
Common Warts ◽  
History Of

Verruca or warts are common significant cause of cosmetic concern and frustration of the patient. Social activities may  be affected. Verruca are formed by benign proliferations of the skin and mucosa that are caused by infection with  Human papilloma virus (HPV). These viruses do not produce acute signs or symptoms but induce a slow, focal expansion of epithelial cells. There are 100 types of Human papilloma virus (HPV). The natural history of common warts is for most of them to spontaneously resolve. But lesions are sometime uncomfortable. Warts typically continue to increase in size and distribution and may become more resistant to treatment over time. A significant  proportion of women with genital HPV infection develops  low-grade cervical lesions. Most of these low-grade lesions regress spontaneously; one study suggests that  approximately 15 percent progress to high-grade cervical  lesions within two years. High-grade cervical lesions have  a strong malignant potential; one study found that about one-third of high-grade lesions progress to cancer within ten years. DOI: http://dx.doi.org/10.3329/jbcps.v30i3.12465 J Bangladesh Coll Phys Surg 2012; 30: 151-158

scholarly journals Human Papilloma Virus Infection and Anal Squamous Intraepithelial Lesions

2019 ◽  
Vol 32 (05) ◽  
pp. 347-357 ◽  
Author(s):  
Laura Svidler López ◽  
Luciana La Rosa
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Human Papilloma Virus ◽  
Human Papilloma Virus Infection ◽  
Hpv Infection ◽  
Squamous Intraepithelial Lesions ◽  
Papilloma Virus ◽  
History Of ◽  
Anal Squamous Intraepithelial Lesions ◽  
Intraepithelial Lesions

AbstractThis article addresses the natural history of the human papilloma virus (HPV) infection to anal squamous intraepithelial lesions, and onto squamous cell carcinoma of the anus. This article provides overviews of the virology, pathophysiology, nomenclature, classification, historical terms, risk factors, clinical evaluation, differential diagnosis, and treatment of HPV infection and its sequelae.

Bracken and cancer

1982 ◽  
Vol 81 (1-2) ◽  
pp. 79-83 ◽  
Author(s):  
W. F. H. Jarrett
Keyword(s):  
Dna Sequences ◽  
Beef Cows ◽  
Malignant Tumours ◽  
Viral Dna ◽  
Papilloma Virus ◽  
Multi Stage ◽  
High Incidence ◽  
History Of ◽  
Stage Process ◽  
The Relationship

SynopsisThere is a high incidence of cancer in beef cows in certain sharply localised geographic calf-rearing areas in Britain and also in cattle in several other parts of the world. The tumours occur on farms which are highly infested with bracken fern and which have a history of bracken poisoning. Bracken is known to cause intestinal and bladder cancer in rats and recently the flavonol, quercetin, has been shown to be a mitogen and to be carcinogenic in rats. Bracken contains large amounts of quercetin. In addition the animals have a high incidence of papillomas of the alimentary tract and these transform to malignant tumours. A new and unique papilloma virus has been isolated from these tumours. Studies using genetic engineering and DNA hybridisation techniques have shown that both alimentary and urinary bladder tumours contain viral DNA sequences. The relationship between bracken, quercetin and viral DNA sequences is under investigation both in cattle and at the molecular biology level as two possible stages in a multi-stage process in the aetiology of a high incidence naturally occurring cancer.

scholarly journals Distinction between vaginal and cervical microbiota in high-risk human papilloma virus-infected women in China

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zhan Zhang ◽  
Ting Li ◽  
Dai Zhang ◽  
Xiaonan Zong ◽  
Huihui Bai ◽  
...  
Keyword(s):  
High Risk ◽  
Human Papilloma Virus ◽  
Cervical Carcinoma ◽  
Female Genital Tract ◽  
Hpv Infection ◽  
Lower Percentage ◽  
Rrna Gene ◽  
Cervical Lesions ◽  
Papilloma Virus ◽  
Significant Difference

Abstract Background High-risk human papilloma virus (hrHPV) is the main causal factor of cervical precancer and cancer when persistent infection is left untreated. Previous studies have confirmed the vaginal microbiota is associated with HPV infection and the development of cervical lesions. The microbiota at different parts of the female genital tract is closely related but different from each other. To analyze the distinction between the vaginal and cervical microbiota of hrHPV(+) women in China, one hundred subjects were recruited, including 10 patients with HPV16/18(+) and cervical carcinoma, 38 patients with HPV16/18(+) but no cervical carcinoma, 32 patients with other hrHPV(+) and 20 healthy controls with HPV(−). Vaginal and cervical microbiota were separately tested through next-generation sequencing (NGS) targeting the variable region (V3-V4) of the bacterial ribosome 16S rRNA gene. Results HrHPV(+) subjects had higher percentages of vaginal douching history (P = 0.001), showed more frequent usage of sanitary pads (P = 0.007), had more sex partners (P = 0.047), were more sexually active (P = 0.025) and more diversed in ways of contraception (P = 0.001). The alpha diversity of the cervical microbiota was higher than that of the vagina. The cervical microbiota consisted of a lower percentage of Firmicutes and a higher percentage of Proteobacteria than the vagina at the phylum level. Sphingomonas, belonging to α-Proteobacteria, was almost below the detection limit in the vagina but accounted for five to 10 % of the bacteria in the hrHPV(−) cervix (P<0.001) and was inversely associated with hrHPV infection (P<0.05). Pseudomonas, belonging to γ-Proteobacteria, could hardly be seen in the normal vagina and shared a small percentage in the normal cervix but was significantly higher in the HPV16/18(+) (P<0.001) and cancerous cervix (P<0.05). No significant difference was shown in the percentage of BV associated anaerobes, like Gardnerella, Prevotella, Atopobium and Sneathia, between the cevix and vigina. Conclusions The proportion of Proteobacteria was significantly higher in the cervical microbiota than that of vagina. The hrHPV infection and cervical cancer was positively associated with Pseudomonas and negatively associated with Sphingomonas. It is of great improtance to deeply explore the cervical microbiota and its function in cervical cacinogenesis.

scholarly journals Tracheal Papilloma Treated with Cryotherapy and Interferon-α: A Case Report and Review of the Literature

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Fatma Yıldırım ◽  
Murat Türk ◽  
Sedat Demircan ◽  
Nalan Akyürek ◽  
Ahmet Selim Yurdakul
Keyword(s):  
Respiratory Symptoms ◽  
Bronchial Epithelium ◽  
Hpv Infection ◽  
Interferon Α ◽  
Tracheal Lumen ◽  
Review Of The Literature ◽  
Papilloma Virus ◽  
Chest Computed Tomography ◽  
Progressive Dyspnea ◽  
History Of

Tracheal papilloma (TP) is characterized by papillomatous growth of the bronchial epithelium that involves the trachea as a response to Human Papilloma Virus (HPV) infection. A 40-year-old male, with 3-month history of progressive dyspnea was admitted to our hospital, and there were no any other respiratory symptoms. Physical examination was unremarkable. Chest computed tomography (CT) showed that there was a papillomatous mass at the distal trachea. The lesion occupied 80% of tracheal lumen. This patient received cryotherapy and mechanical debridement under general anesthesia and postoperative pathology showed endotracheal papillomatosis. Patient was treated with interferon-α(IFN-α) and he showed no recurrence at the 8th month of his therapy.

Immunotheraphy in Allergic Diseases

2018 ◽  
Vol 24 (11) ◽  
pp. 1174-1194
Author(s):  
Albert Roger ◽  
Maria Basagana ◽  
Aina Teniente-Serra ◽  
Nathalie Depreux ◽  
Yanina Jurgens ◽  
...  
Keyword(s):  
Specific Immunotherapy ◽  
Allergic Diseases ◽  
Specific Ige ◽  
World Population ◽  
Allergen Specific Immunotherapy ◽  
Routes Of Administration ◽  
Disease Modifying Therapy ◽  
History Of ◽  
Ige Mediated ◽  
Special Case

The prevalence of allergic diseases is increasing worldwide. It is estimated that more than 30% of the world population is now affected by one or more allergic conditions and a high proportion of this increase is in young people. The diagnosis of allergy is dependent on a history of symptoms on exposure to an allergen together with the detection of allergen-specific IgE. Accurate diagnosis of allergies opens up therapeutic options. Allergen specific immunotherapy is the only successful disease-modifying therapy for IgE-mediated allergic diseases. New therapeutic strategies have been developed or are currently under clinical trials. Besides new routes of administration, new types of allergens are being developed. The use of adjuvants may amplify the immune response towards tolerance to the antigens. In this review, we analyze different antigen-specific immunotherapies according to administration route, type of antigens and adjuvants, and we address the special case of food allergy.

A new approach to the logic of discovery

2007 ◽  
Vol 50 (1) ◽  
pp. 7-27
Author(s):  
Gerald Massey
Keyword(s):  
Modal Logic ◽  
Scientific Discovery ◽  
Traditional View ◽  
New Approach ◽  
Logic Of Discovery ◽  
Good Fortune ◽  
High Incidence ◽  
History Of ◽  
Deep Sense

Contending that the quest for a logic of scientific discovery was prematurely abandoned, the author lays down eight phenomena that such a logic or theory must explain: the banality of scientific discovery; the trainability of scientists; the high incidence of simultaneous discoveries; the ubiquity of relative novices; the fact of scientific genius; the barrenness of isolated workers; the incommensurability of concepts of successive theories; and the quasi-incorporation of old concepts, objects, and methods in successor theories, The author then presents a new theory or logic of discovery according to which discoveries are the termini of "tweak paths" generated when scientists "tinker" with the laws, concepts, methods, and instruments of a given theory. Tinkering and tweaking are illustrated by examples from many-valued and modal logic and from Darwinian biology. Through the history of planetary discovery, the accidental role played by luck or good fortune in some discoveries is explored, but the author emphasizes that in a deep sense serendipity is an in eliminable feature of all scientific discovery because scientists never know m advance whether their tweaks will lead to dead ends or to positive developments. The author's new theory of scientific discovery is shown to account for all eight explananda, ft also reveals science to be a more egalitarian enterprise than the traditional view of scientific discovery as ultimately inexplicable depicts it.

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