scholarly journals Tracheal Papilloma Treated with Cryotherapy and Interferon-α: A Case Report and Review of the Literature

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Fatma Yıldırım ◽  
Murat Türk ◽  
Sedat Demircan ◽  
Nalan Akyürek ◽  
Ahmet Selim Yurdakul
Keyword(s):  
Respiratory Symptoms ◽  
Bronchial Epithelium ◽  
Hpv Infection ◽  
Interferon Α ◽  
Tracheal Lumen ◽  
Review Of The Literature ◽  
Papilloma Virus ◽  
Chest Computed Tomography ◽  
Progressive Dyspnea ◽  
History Of

Tracheal papilloma (TP) is characterized by papillomatous growth of the bronchial epithelium that involves the trachea as a response to Human Papilloma Virus (HPV) infection. A 40-year-old male, with 3-month history of progressive dyspnea was admitted to our hospital, and there were no any other respiratory symptoms. Physical examination was unremarkable. Chest computed tomography (CT) showed that there was a papillomatous mass at the distal trachea. The lesion occupied 80% of tracheal lumen. This patient received cryotherapy and mechanical debridement under general anesthesia and postoperative pathology showed endotracheal papillomatosis. Patient was treated with interferon-α(IFN-α) and he showed no recurrence at the 8th month of his therapy.

Bladder Condyloma Acuminatum, A Case Report

2020 ◽  
pp. 1-3
Author(s):  
Villalba Bachur Roberto ◽  
◽  
Spagnuolo Juan Ignacio ◽  
Cora Florencia ◽  
◽  
...  
Keyword(s):  
Cervical Carcinoma ◽  
Hpv Infection ◽  
Cancer Case ◽  
World Population ◽  
Single Episode ◽  
Papilloma Virus ◽  
High Incidence ◽  
Bladder Cancer Case ◽  
History Of ◽  
Laser Enucleation

Background: Human Papilloma virus (HPV) infection is a high incidence entity in the world population. It is highly related to cervical carcinoma, as well as anogenital carcinoma, among others. The presences of bladder HPV lesions are infrequent and there is an association between it and the development of bladder cancer. Case presentation: We present a case of bladder HPV in a woman with a cervical carcinoma history that was presented clinically as a single episode of gross hematuria. We performed a cystoscopy and Holmium laser enucleation of the bladder tumors. Conclusion: We highlight the importance of consider HPV as a differential diagnosis of a bladder tumor, mainly in patients with history of pathologies related with the virus.

scholarly journals Verruca: Need to Know about Human Papilloma Virus (HPV) Infection

2012 ◽  
Vol 30 (3) ◽  
pp. 151-158 ◽  
Author(s):  
Lubna Khondker ◽  
Md Obaidur Rahman Shah ◽  
Md Shirajul Shirajul Islam Khan
Keyword(s):  
Human Papilloma Virus ◽  
Significant Proportion ◽  
Hpv Infection ◽  
Malignant Potential ◽  
Low Grade ◽  
High Grade ◽  
Cervical Lesions ◽  
Papilloma Virus ◽  
Common Warts ◽  
History Of

Verruca or warts are common significant cause of cosmetic concern and frustration of the patient. Social activities may  be affected. Verruca are formed by benign proliferations of the skin and mucosa that are caused by infection with  Human papilloma virus (HPV). These viruses do not produce acute signs or symptoms but induce a slow, focal expansion of epithelial cells. There are 100 types of Human papilloma virus (HPV). The natural history of common warts is for most of them to spontaneously resolve. But lesions are sometime uncomfortable. Warts typically continue to increase in size and distribution and may become more resistant to treatment over time. A significant  proportion of women with genital HPV infection develops  low-grade cervical lesions. Most of these low-grade lesions regress spontaneously; one study suggests that  approximately 15 percent progress to high-grade cervical  lesions within two years. High-grade cervical lesions have  a strong malignant potential; one study found that about one-third of high-grade lesions progress to cancer within ten years. DOI: http://dx.doi.org/10.3329/jbcps.v30i3.12465 J Bangladesh Coll Phys Surg 2012; 30: 151-158

scholarly journals Human Papilloma Virus Infection and Anal Squamous Intraepithelial Lesions

2019 ◽  
Vol 32 (05) ◽  
pp. 347-357 ◽  
Author(s):  
Laura Svidler López ◽  
Luciana La Rosa
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Human Papilloma Virus ◽  
Human Papilloma Virus Infection ◽  
Hpv Infection ◽  
Squamous Intraepithelial Lesions ◽  
Papilloma Virus ◽  
History Of ◽  
Anal Squamous Intraepithelial Lesions ◽  
Intraepithelial Lesions

AbstractThis article addresses the natural history of the human papilloma virus (HPV) infection to anal squamous intraepithelial lesions, and onto squamous cell carcinoma of the anus. This article provides overviews of the virology, pathophysiology, nomenclature, classification, historical terms, risk factors, clinical evaluation, differential diagnosis, and treatment of HPV infection and its sequelae.

scholarly journals Noninfectious papilloma virus–like particles inhibit HIV-1 replication: implications for immune control of HIV-1 infection by IL-27

Blood ◽  
2006 ◽  
Vol 109 (5) ◽  
pp. 1841-1849 ◽  
Author(s):  
J. Mohamad Fakruddin ◽  
Richard A. Lempicki ◽  
Robert J. Gorelick ◽  
Jun Yang ◽  
Joseph W. Adelsberger ◽  
...  
Keyword(s):  
T Cells ◽  
Cd4 T Cells ◽  
Mononuclear Cells ◽  
Interleukin 10 ◽  
Hpv Infection ◽  
Interferon Α ◽  
Novel Therapy ◽  
Peripheral Blood Mononuclear ◽  
Papilloma Virus ◽  
Hiv 1

AbstractHuman papilloma virus (HPV)–like particles (VLPs) have been used as a vaccine to prevent HPV infection. Recent studies demonstrate that VLPs bind to dendritic cells and induce the expression of antiviral cytokines such as interferon-α (IFN-α), interleukin-10 (IL-10) and IFN-γ. In the present study, we evaluated the effect of VLPs on HIV-1 replication in peripheral blood mononuclear cells (PBMCs), CD4+ T cells, and macrophages. Here, we show that VLPs suppress the replication of both X4 and R5 HIV-1 without affecting the expression of CD4, CXCR4, and CCR5. Soluble factor(s) released by PBMCs and macrophages on VLPs treatment inhibited HIV-1 replication. To determine the inhibitory factors, DNA microarray analysis was performed using VLP-treated PBMCs and macrophages. VLPs induced the genes associated with IFN induction, immune responses, and antiviral responses, among with the recently described cytokine IL-27. Subsequently, IL-27 was found to be a potent inhibitor of HIV-1 replication in PBMCs, CD4+ T cells, and macrophages. Taken together, our studies identify a novel role of IL-27 in restricting HIV-1 replication and suggest that further examination of the inhibitory property of IL-27 may pave the way for a novel therapy for HIV-1 infection.

Pneumomediastinum: A Rare Presentation of Inflicted Injuries in Infants

2020 ◽  
Author(s):  
Adam Lee ◽  
Adam Bajinting ◽  
Abby Lunneen ◽  
Colleen M. Fitzpatrick ◽  
Gustavo A. Villalona
Keyword(s):  
Literature Review ◽  
Retrospective Review ◽  
Review Of The Literature ◽  
Rare Presentation ◽  
Spontaneous Pneumomediastinum ◽  
Nonaccidental Trauma ◽  
Comprehensive Literature Review ◽  
Healthy Infants ◽  
History Of

AbstractReports of incidental pneumomediastinum in infants secondary to inflicted trauma are limited. A retrospective review of infants with pneumomediastinum and history of inflicted trauma was performed. A comprehensive literature review was performed. Three infants presented with pneumomediastinum associated with inflicted trauma. Mean age was 4.6 weeks. All patients underwent diagnostic studies, as well as a standardized evaluation for nonaccidental trauma. All patients with pneumomediastinum were resolved at follow-up. Review of the literature identified other cases with similar presentations with related oropharyngeal injuries. Spontaneous pneumomediastinum in previously healthy infants may be associated with inflicted injuries. Clinicians should be aware of the possibility of an oropharyngeal perforation related to this presentation.

scholarly journals History of Extensive Disease Small Cell Lung Cancer Treatment: Time to Raise the Bar? A Review of the Literature

Cancers ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 998
Author(s):  
Chiara Lazzari ◽  
Aurora Mirabile ◽  
Alessandra Bulotta ◽  
Maria Grazia Viganó ◽  
Francesca Rita Ogliari ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Treatment Time ◽  
Small Cell ◽  
Review Of The Literature ◽  
Small Cell Lung ◽  
Extensive Disease ◽  
History Of ◽  
Line Standard

Several trials have tried for decades to improve the outcome of extensive disease small cell lung cancer (ED-SCLC) through attempts to modify the standard treatments. Nevertheless, platinum/etoposide combination and topotecan have remained respectively the first and the second line standard treatments for the last 40 years. With the advent of immunotherapy, this scenario has finally changed. Our review aims to provide an overview of the primary studies on the actual therapeutic strategies available for ED-SCLC patients, and to highlight emerging evidence supporting the use of immunotherapy in SCLC patients.

scholarly journals Awareness and Knowledge about Human Papilloma Virus Infection among Students at Secondary Occupational Health School in China

2021 ◽  
Vol 18 (12) ◽  
pp. 6321
Author(s):  
Xin Wang ◽  
Taifeng Du ◽  
Xiaoling Shi ◽  
Kusheng Wu
Keyword(s):  
Occupational Health ◽  
Human Papilloma Virus ◽  
Healthcare Providers ◽  
Human Papilloma Virus Infection ◽  
First Grade ◽  
Hpv Infection ◽  
Cross Sectional Study ◽  
Causal Link ◽  
Cross Sectional ◽  
Papilloma Virus

Cervical cancer (CC) is one of the most common causes of cancer-related deaths worldwide. CC is mainly caused by human papilloma virus (HPV), which can be prevented by vaccination. We conducted a cross-sectional study in secondary occupational health school (SOHS) through a questionnaire aimed to assess the awareness and knowledge regarding HPV infection of students. A total of 2248 students participated in the survey, 45.3% of them had heard about CC, while only 21.9% of them had heard about HPV; and 74.2% had no idea of the causal link between HPV infection and CC. Most participants displayed poor awareness and knowledge about HPV infection. The results suggested that age, grade, major, academic performance, etc. were correlated with higher awareness of CC, HPV and HPV infection (p < 0.05). In multivariable logistic analysis, third-grade students had the most increased awareness of CC (OR = 17.13, 95%CI: [8.11, 36.15]), HPV (OR = 6.59, 95%CI: [4.16, 10.43]) and HPV vaccine (OR = 2.78, 95%CI: [1.78, 4.32]) when compared to first-grade. Awareness and knowledge regarding HPV infection were insufficient among students in SOHS. As the future healthcare providers, these results highlight the need to supplement targeted education to improve their awareness and knowledge of HPV and vaccination.

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