scholarly journals Effect of Educational Status on Underweight among Lactating Women in Ethiopia A Systemic Review and Meta-Analysis

2021 ◽  
pp. 1-6
Author(s):  
Wosenyeleh Semeon Bagajjo ◽  
◽  
Kaleab Tesfaye Tegegne ◽  
Berhanu Bifato ◽  
Abiyu Ayalew Assefa ◽  
...  
Keyword(s):  
Informal Education ◽  
Formal Education ◽  
Assessment Tool ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Educational Status ◽  
Systemic Review ◽  
Health Extension Workers ◽  
Lactating Women

Objective: The objective of this systemic review and meta-analysis was to examine the relationship between educational status and underweight among lactating women in Ethiopia The studies conducted before indicate in consistence association between educational status and underweight among lactating women in Ethiopia. We include 7 studies in different regions of Ethiopia. Materials and Methods: The databases, including PubMed, Google scholar were systematically searched from 2015 to 2020. Data were extracted and tabulated by two reviewers using a table containing the following variables: author, title, date of publication, city(s)/ Region / study design, sample size, percentage women with informal education and percentage women with formal education and underweight. The Newcastle-Ottawa Scale for cross-sectional studies quality assessment tool was adapted and used to assess the quality of each study. The combined adjusted Odds ratios (OR)) and 95% confidence intervals were calculated using random effect model. Results: In the current meta-analysis seven observational studies involving 3113 lactating women’s were used to estimate the pooled effect size of underweight. The result of 7 included studies indicated that the pooled odd ratio of underweight among women with informal education compared with women with formal education in Ethiopia was 2.47 (95% CI: 1.69, 3.83). Publication bias for estimating the odd ratio of underweight for women with informal education compared to women with formal education (p = 0.881) and (p = 0.649 ) respectively Heterogeneity was statistically significant (I2=76% Q=25.06; P<0•001). From 54.35% (1692) women who have informal education 16.35% (509) women have underweight. The overall proportion of underweight was 16.35% and 6.58% for those having informal education and formal education respectively. Conclusions: There was evidence that lactating mothers with informal education are more likely to experience underweight. Based on our findings, we strongly recommended that the health education activities about nutrition should be targeted among lactating women with informal education through health extension workers

scholarly journals Regional and chronological differences in prevalences of olfactory and gustatory dysfunction in coronavirus disease (COVID-19): a systemic review and meta-analysis

2020 ◽  
Author(s):  
Jeong-Whun Kim ◽  
Seung Cheol Han ◽  
Hyung Dong Jo ◽  
Sung-Woo Cho ◽  
Jin Youp Kim
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Olfactory Dysfunction ◽  
Systemic Review ◽  
Effect Model ◽  
Geographical Regions ◽  
Significant Difference ◽  
Subgroup Analyses

Abstract Olfactory and gustatory dysfunction are frequently reported in patients with coronavirus disease (COVID-19). However, the reported prevalence of olfactory and/or gustatory dysfunction varies widely, and the reason for the inter-study differences is unclear. Hence, in this meta-analysis, we performed subgroup analyses to investigate the factors that contribute to the inter-study variability in the prevalence of olfactory and gustatory dysfunction. Out of 943 citations, we included 55 eligible studies with 13,527 patients with COVID-19 for a systematic review. The overall pooled prevalences of olfactory and gustatory dysfunction were 51.4% and 47.5%, respectively, in the random-effect model. In subgroup analyses, the prevalences of olfactory and gustatory dysfunction were significantly different among four geographical regions (both P < 0.001, respectively). Although the prevalences of olfactory and gustatory dysfunction did not significantly differ according to the time of enrollment, the subgroup analyses including only studies from the same geographical region (Europe) revealed a significant difference in olfactory dysfunction according to the time of enrollment. The regional and chronological differences in the prevalences of olfactory and gustatory dysfunctions partly explain the wide inter-study variability.

scholarly journals Predictors of unmet need for family planning in Ethiopia 2019: a systematic review and meta analysis

2020 ◽  
Vol 78 (1) ◽  
Author(s):  
Temesgen Getaneh ◽  
Ayenew Negesse ◽  
Getenet Dessie ◽  
Melaku Desta ◽  
Tebabere Moltot
Keyword(s):  
Family Planning ◽  
Formal Education ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Unmet Need ◽  
Reproductive Age ◽  
Early Marriage ◽  
Cochrane Library ◽  
Pooled Prevalence

Abstract Background unmet need for family planning is a common cause of uninteded pregnancy which mostly end up with abortion. Many studies were conducted on predictors of unmet need of family planning in Ethiopia. But, up until now, single evidence has not been synthesized and various point prevalence estimates of unmet need for family planning have been reported. Therefore, this sytematic review and meta analysis was established to identify the predictors of unmet need for family planning in Ethiopia. Methods search engines including PubMed, Embase, CINAHL, Google Scholar, HINARI portal, and Cochrane Library were used to retrieve included articles and reported using the preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA) checklist guidelines. Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instrument (JBI-MAStARI) was applied for critical appraisal. All observational studies done on reproductive age women and reported on unmet need for family planning were included. Unmet need for family planning is the percentage of women of reproductive age, either married or in a union, who have an unmet need for family planning to stop or delay childbearing. Random effect model was done to estimate the pooled prevalence of unmet need for family planning. Odds ratio with 95% confidence interval was considered to determine the association of identified variables with unmet need of family planning. Cochran’s Q statistic, Egger’s and Begg’s test were carried out to assess heterogeneity and publication bias. Results Fifteen articles and 17, 585 reproductive aged women were included to estimate the pooled prevalence of unmet need for family planning and its predictors in Ethiopia. The prevalence of unmet need for family planning in Ethiopia ranges from 26.52 to 36.39%. Age at first marriage < 18 yrs. with OR = 2.3 (95% CI: 1.08, 4.87), women with no formal education with OR = 1.9 (95%CI: 1.19, 3.04), partner with no formal education with OR = 1.78 (95%CI: 1.18, 2.68) and absence of discussion with their partner about family planning with OR = 3.52 (95%CI, 2.56, 4.87) were predictors of unmet need of family planning in Ethiopia. Conclusion This meta analysis revealed that, the prevalence of unmet need for family planning in Ethiopia was high as compared with the United Nations sphere standard of unmet need for planning, considered to be high if it is greater than 25%. Early marriage, no formal eduaction and lack of discussion with partner on family planning were predictors of unmet need for family planning. Therefore, efforts are needed to empower women through eduaction, avoiding early marriage and facilitating dicussion of partners about family planning in order to improve family planning usage.

scholarly journals Association Between Circulating Proprotein Convertase Subtilisin/Kexin Type 9 Concentrations and Cardiovascular Events in Cardiovascular Disease: A Systemic Review and Meta-Analysis

2021 ◽  
Vol 8 ◽  
Author(s):  
Jiahui Liu ◽  
Fangfang Fan ◽  
Xingyu Luo ◽  
Wenjun Ji ◽  
Yaokun Liu ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Positive Association ◽  
Systemic Review ◽  
Proprotein Convertase ◽  
Pcsk9 Inhibitors ◽  
Clinical Role ◽  
Increased Risk

Background: A large amount of evidence suggests that proprotein convertase subtilisin/Kexin type 9 (PCSK9) inhibitors have clinical benefits in patients with cardiovascular disease (CVD). However, whether PCSK9 concentrations predict future cardiovascular (CV) events remains unclear.Methods: We conducted a meta-analysis to investigate the ability of PCSK9 concentrations to predict future CV events in patients with established CVD. A comprehensive search of electronic databases was conducted in June 2021. We included relative risk (RR) estimates with 95% CI or events of interest.Results: Eleven cohort studies including 8,471 patients with CVD were enrolled. The pooled RR of CV events for the increase in the circulating baseline PCSK9 concentrations by 1 SD showed a positive association in a random-effect model (RR 1.226, 95% CI: 1.055–1.423, P = 0.008). Similarly, the risk of the total CV events increased by 52% in the patients in the highest tertile compared with those in the lowest tertile of circulating PCSK9 concentrations (RR 1.523, 95% CI: 1.098–2.112, P = 0.012). The association between PCSK9 and CV events was stronger in stable patients with CVD, patients treated with statins, and Asian patients.Conclusions: High PCSK9 concentrations are significantly related to the increased risk of future CV events. These results enrich the knowledge of PCSK9 function and suggest the further possible clinical role of PCSK9 inhibitors.

scholarly journals Post-operative day 3 Procalcitonin predicts post-operative infectious complications in pancreatic surgery A systemic review and updated meta-analysis.

2020 ◽  
Author(s):  
BHAVIN VASAVADA ◽  
hardik patel
Keyword(s):  
Odds Ratio ◽  
Pancreatic Surgery ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Diagnostic Odds Ratio ◽  
Infectious Complications ◽  
Systemic Review ◽  
Geometric Means ◽  
Sensitivity Specificity

Aim of study: Aim of this meta-analysis is to evaluate post-operative procalcitonin as a marker to predict post- operative infectious complications after pancreatic surgeries. Material and Methods: Systemic literature search was performed using MEDLINE, EMBASE and to identify studies evaluating the diagnostic accuracy of Procalcitonin (PCT) as a predictor for detecting infectious complications on postoperative days (POD) 3 and 5 following pancreatic surgery. A meta-analysis was performed using random effect model and pooled predictive parameters for POD 3 and 5 were derived. Geometric means were calculated for PCT cut offs. Results: 6 studies included day 3 PCT analysis, 2 studies included both day 3 and day 5 analysis. Total data of 471 patients were derived. 161 patients developed infectious complications. Pooled sensitivity, specificity, pooled area under curve, diagnostic odds ratio (DOR), positive and negative like hood ratio of day 3 PCT were 74%,79%,0.8453, 11.03,3.17 and 0.31 respectively. Pooled sensitivity, specificity, diagnostic odds ratio (DOR), positive and negative like hood ratio of day 5 PCT were 83%,70%,12.91,2.91 and 0.25 respectively. Geometric means for PCT cut off for day 3 and 5 were 0.80 and 0.43. Conclusion: Postoperative procalcitonin particularly day 3 procalcitonin levels predict post-operative infectious complications following pancreatic surgeries.

Association Between Ambient Air Pollution and Multiple Sclerosis: a Systemic Review and Meta-Analysis

2021 ◽  
Author(s):  
Chao Tang ◽  
Qing-Ru Li ◽  
Yan-Mei Mao ◽  
Yuan-Rui Xia ◽  
Heng-Sheng Guo ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Air Pollution ◽  
Air Pollutants ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
Systemic Review ◽  
Cochrane Library

Abstract The effects of air pollutants on autoimmune diseases are gaining increasing attention. At present, no studies have conducted systemic review and meta-analysis on ambient air pollution and multiple sclerosis (MS). In this paper, literature was collected in order to explore whether there was a connection between air pollutants and MS or not. Through electronic literature search, literature related to our research topic was collected in Cochrane Library, Embase and Pubmed till August 18, 2020 according to certain criteria. Pooled risk estimate and 95% confidence intervals (95%CI) were calculated by random-effect model analysis. After removing copies, browsing titles and abstracts and reading full text, 6 studies were finally included. The results showed that only particulate matter (PM) with aerodynamic diameter ≤10 (PM10) was related to MS (pooled HR=1.058, 95% CI=1.050-1.066), and no correlation was found between other pollutants and MS. There was no publication bias, and the heterogeneity analysis results were stable. PM is correlated with the disease MS, while other pollution is not connected with MS. More literature results need to be included to meta-analysis results for further study.

scholarly journals Was Antiphospholipid Syndrome a Risk Factor of Stroke? A Systemic Review and Meta-Analysis of Cohort Studies

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Kai Zhao ◽  
Ping Zhou ◽  
Ling Xu ◽  
Ruili Li ◽  
Jincai Yang ◽  
...  
Keyword(s):  
Risk Factor ◽  
Autoimmune Diseases ◽  
Cohort Studies ◽  
Publication Bias ◽  
Antiphospholipid Syndrome ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Systemic Review ◽  
Effect Model

Antiphospholipid syndrome (APS) is characterized by thrombosis. This systemic review and meta-analysis was to verify the hypothesis that APS might increase the risk of stroke. Studies were identified after literature searching of PubMed, Embase, and Cochrane. Newcastle-Ottawa Quality Assessment Scale Cohort Studies (NOQAS-C) was used to assess the quality of studies. The pooled effect with 95% confidence interval (95% CI) was calculated by random-effect model. I -square ( I 2 ) was used to test heterogeneity. Funnel plot was used to evaluate publication bias. A total of 17 cohort studies with overall high quality were included. There was no publication bias. Pooled hazard ratio of stroke occurrence in APS patients was 1.76 (1.39-2.21) with low heterogenicity and stable result from sensitivity analysis. In the analysis of subgroups, pooled risk ratios of stroke occurrence in patients with only positive antibodies of APS diagnosis were 1.75 (0.99-3.09), which for the APS patients with other autoimmune diseases were 14.70 (7.56-28.56). APS might be a risk factor of stroke, especially in patients with other autoimmune diseases.

scholarly journals Awareness, Knowledge, Attitude, and Practice of Teledentistry among Dental Practitioners during COVID-19: A Systematic Review and Meta-Analysis

Medicina ◽  
2022 ◽  
Vol 58 (1) ◽  
pp. 130
Author(s):  
Galvin Sim Siang Lin ◽  
Sze Hui Koh ◽  
Karyn Zuhuan Ter ◽  
Chia Wei Lim ◽  
Sharmin Sultana ◽  
...  
Keyword(s):  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Systemic Review ◽  
Level Of Evidence ◽  
Cross Sectional ◽  
Attitude And Practice ◽  
Dental Practitioners ◽  
Knowledge Attitude And Practice ◽  
Poor Practice

Background and Objectives: This systemic review aims to appraise and analyse the awareness, knowledge, attitude, and practice of teledentistry among dental practitioners during COVID-19. Materials and Methods: This review was registered in the PROSPERO database (CRD42021283404). Cross-sectional articles on dental practitioners’ perceptions towards teledentistry published between March 2020 and September 2021 were searched in ten online databases (PubMed, Google Scholar, Web of Science, ScienceDirect, Cochrane, EMBASE, SIGLE, EBSCO, LILACS, and Open Grey). The Joanna Briggs Institute critical appraisal tool was employed to analyse the risk of bias (RoB) of each article, whereas the Oxford Centre for Evidence-Based Medicine recommendation tool was used to evaluate the level of evidence. Data were analysed using the DerSimonian–Laird random effect model based on a single-arm approach. Results: Six studies were included and demonstrated Level 3 evidence. A single-arm meta-analysis revealed that dental practitioners had a high level of awareness (70.4%) and attitude (72.5%) towards teledentistry during the COVID-19 pandemic, but their knowledge level (57.9%) was moderate with a poor practice level (35.8%). A substantial heterogeneity was observed with the overall I2 ranging from 90.78% to 98.21%. Furthermore, meta-regression indicated that the sample size of each study had a significant (p < 0.05) impact on the degree of data heterogeneity. Conclusions: Despite their high degree of awareness and attitude, dental practitioners demonstrated moderate knowledge and relatively poor practice of teledentistry during the COVID-19 pandemic. More well-designed studies are warranted to investigate the alternatives for enhancing dental practitioners’ knowledge and practice of teledentistry interventions.

scholarly journals Post-Operative Infectious Complications in Pancreatic Surgery – A Systemic Review and Updated Meta-analysis

2020 ◽  
Author(s):  
BHAVIN Vasavada ◽  
hardik patel
Keyword(s):  
Odds Ratio ◽  
Pancreatic Surgery ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Diagnostic Odds Ratio ◽  
Infectious Complications ◽  
Systemic Review ◽  
Geometric Means ◽  
Sensitivity Specificity

Aim of study:Aim of this meta-analysis is to evaluate post-operative procalcitonin as a marker to predict post- operative infectious complications after pancreatic surgeries.Material and Methods:Systemic literature search was performed using MEDLINE, EMBASE and to identify studies evaluating the diagnostic accuracy of Procalcitonin (PCT) as a predictor for detecting infectious complications on postoperative days (POD) 3 and 5 following pancreatic surgery. A meta-analysis was performed using random effect model and pooled predictive parameters for POD 3 and 5 were derived. Geometric means were calculated for PCT cut offs. Results:6 studies included day 3 PCT analysis, 2 studies included both day 3 and day 5 analysis. Total data of 471 patients were derived. 161 patients developed infectious complications. Pooled sensitivity, specificity, pooled area under curve, diagnostic odds ratio (DOR), positive and negative like hood ratio of day 3 PCT were 74%,79%,0.8453, 11.03,3.17 and 0.31 respectively. Pooled sensitivity, specificity, diagnostic odds ratio (DOR), positive and negative like hood ratio of day 5 PCT were 83%,70%,12.91,2.91 and 0.25 respectively. Geometric means for PCT cut off for day 3 and 5 were 0.80 and 0.43. Conclusion:Postoperative procalcitonin particularly day 3 procalcitonin levels predict post-operative infectious complications following pancreatic surgeries.

scholarly journals E-Cigarettes and myocardial Infarction: a systemic review and meta-analysis

2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
A Sharma ◽  
I Gupta ◽  
V U ◽  
R Golamari
Keyword(s):  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Systemic Review ◽  
Major Adverse Cardiovascular Events ◽  
Forest Plot ◽  
P Value ◽  
Funding Sources ◽  
Effect Model ◽  
Harmful Effects

Abstract Funding Acknowledgements Type of funding sources: None. Introduction With widespread awareness about the harmful effects of traditional smoking, many people are considering the use of an e-cigarette. However, there are many studies which have shown  e-cigarettes is not entirely harmless and it’s use has been implication in causing major adverse cardiovascular events. Methodology This systemic review strictly adhered to the PRISMA checklist. An electronic search was conducted comprehensively through five databases to find the relevant articles. The odds ratio (OR) was used for comparing groups. Meta-analysis was conducted using R statistical software version 3.4.3. A random-effect model was used. Results A total of 4 studies were included in the analysis incorporating data on 585,306 subjects. In these, 19,435 were e-cigarettes users, while 1693 used only traditional cigarette users, and 553,095 were non-e-cigarette users. A total of 7.0% of e-cigarette users suffered an MI in their lifetime, while only 6.5% of non-e-cigarette users have had MI. The OR of getting an MI in e-cigarettes users was 1.30 (95% CI = 1.23-1.38, p-value &lt; 0.01) in comparison to non e-cigarette users. While it is 0.61 (95% CI = 0.40 – 0.93, p-value 0.02) when compared with traditional smoking. Conclusion Those using e-cigarettes have a higher odds of suffering from an MI in comparison to not using e-cigarettes. However, using e-cigarettes reduces the risk of MI by half in comparison to traditional smoking. Abstract Figure. Forest plot

Antenatal Care Predicts Neonatal Mortality in Eastern Africa: A Systematic Review and Meta-analysis of Observational Studies

2022 ◽  
pp. 097321792110688
Author(s):  
Getahun Tiruye ◽  
Kasiye Shiferaw ◽  
Addisu Shunu ◽  
Yitagesu Sintayeu ◽  
Abdulbasit Musa Seid
Keyword(s):  
Antenatal Care ◽  
Neonatal Mortality ◽  
Assessment Tool ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Eastern Africa ◽  
Eastern Region ◽  
African Countries ◽  
Pregnancy And Childbirth

Background Sub-Saharan African countries, especially the Eastern region, present the dismal picture of neonatal mortality (NM) in the globe. The majority of these deaths could be avoided if effective health measures are provided throughout pregnancy and childbirth. Although antenatal care (ANC) is assumed as one of the viable interventions that contribute to neonatal survival, the effect of ANC on NM was not systematically analyzed in Eastern Africa. Thus, the study aimed to determine the pooled effect of ANC on NM in Eastern Africa. Methods PubMed, EMBASE, CINAHL, and HINARI databases were searched using appropriate keywords from January 1, 1990 to February 12, 2021. Independent authors selected eligible articles and extracted data. The risk of a bias assessment tool for nonrandomized studies was used to assess the quality of the study. Comprehensive meta-analysis version 2 was used for meta-analysis. The random-effect model was employed, and the outcome is expressed as a risk ratio with 95% confidence interval (CI). Results In total, 1149 studies were identified through database search, and only 27 studies were included in the meta-analysis. Having at least 1 ANC visit during pregnancy reduced the risk of neonatal death by 42% compared to their counterparts (RR = 0.58, 95% CI [0.47, 0.71]). The pooled prevalence of NM was 8.5% (95% CI [7.3, 9.6]), with NM rate of 46.3/1000 live births. Conclusion The study indicated that NM might be decreased even with a single ANC visit when compared to no visits. Scaling up ANC services through ANC promotion and tackling service-related barriers could potentially reduce NM in Eastern Africa.

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