scholarly journals Nanotechnology and Biomedical Applications of Nanotechnology

Author(s):  
Khyati D. Kshirsagar ◽  
Shubham M. Avhad ◽  
Pracheta A. Kuwar

Solid colloidal particles of size from 10 to 1000 Nanometre are known as Nanoparticles. Nanoparticles contribute many benefits to bigger particles such as enhanced surface-to-volume ratio and enhanced magnetic properties. Over the last few years, there has been an undeviating growing interest in using nanoparticles in different biomedical applications such as targeted drug delivery, hyperthermia, photo ablation therapy, bio imaging, and biosensors. Iron oxide nanoparticles have dominated applications, such as drug delivery, hyperthermia, bio imaging, cell labelling, and gene delivery, because of their superior properties such as chemical stability, non-toxicity, biocompatibility, high saturation magnetization, and high magnetic susceptibility. In this paper, biomedical applications of two different types of nanoparticles metal oxide nanoparticles and carbon nanotubes are discussed.

Pharmaceutics ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 1662
Author(s):  
Mahadevamurthy Murali ◽  
Nataraj Kalegowda ◽  
Hittanahallikoppal G. Gowtham ◽  
Mohammad Azam Ansari ◽  
Mohammad N. Alomary ◽  
...  

Zinc oxide nanoparticles have become one of the most popular metal oxide nanoparticles and recently emerged as a promising potential candidate in the fields of optical, electrical, food packaging, and biomedical applications due to their biocompatibility, low toxicity, and low cost. They have a role in cell apoptosis, as they trigger excessive reactive oxygen species (ROS) formation and release zinc ions (Zn2+) that induce cell death. The zinc oxide nanoparticles synthesized using the plant extracts appear to be simple, safer, sustainable, and more environmentally friendly compared to the physical and chemical routes. These biosynthesized nanoparticles possess strong biological activities and are in use for various biological applications in several industries. Initially, the present review discusses the synthesis and recent advances of zinc oxide nanoparticles from plant sources (such as leaves, stems, bark, roots, rhizomes, fruits, flowers, and seeds) and their biomedical applications (such as antimicrobial, antioxidant, antidiabetic, anticancer, anti-inflammatory, photocatalytic, wound healing, and drug delivery), followed by their mechanisms of action involved in detail. This review also covers the drug delivery application of plant-mediated zinc oxide nanoparticles, focusing on the drug-loading mechanism, stimuli-responsive controlled release, and therapeutic effect. Finally, the future direction of these synthesized zinc oxide nanoparticles’ research and applications are discussed.


Author(s):  
Ranhua Xiong ◽  
Ronald X. Xu ◽  
Chaobo Huang ◽  
Stefaan De Smedt ◽  
Kevin Braeckmans

This review presents an overview of the recent advances in the development of stimuli-responsive nanobubbles and their novel biomedical applications including bio-imaging, drug delivery and ablation of tumor tissues.


2022 ◽  
pp. 205-231
Author(s):  
Raj Kumar ◽  
Guruprasad Reddy Pulikanti ◽  
Konathala Ravi Shankar ◽  
Darsi Rambabu ◽  
Venkateswarulu Mangili ◽  
...  

2018 ◽  
Vol 10 (11) ◽  
pp. 666-679 ◽  
Author(s):  
Pahweenvaj Ratnatilaka Na Bhuket ◽  
Jittima Amie Luckanagul ◽  
Pornchai Rojsitthisak ◽  
Qian Wang

Chemistry enables scientists to use enveloped viruses in several biomedical applications including bio-imaging, drug delivery and vaccine development.


2020 ◽  
Vol 20 (6) ◽  
pp. 3303-3339 ◽  
Author(s):  
Saee Gharpure ◽  
Aman Akash ◽  
Balaprasad Ankamwar

The field of nanotechnology elaborates the synthesis, characterization as well as application of nanomaterials. Applications of nanoparticles in various fields have interested scientists since decades due to its unique properties. Combination of pharmacology with nanotechnology has helped in development of newer antimicrobial agents in order to control the ever increasing multidrug resistant micro-organisms. Properties of metal and metal oxide nanoparticles like silver, gold, titanium dioxide as well as magnesium oxide as antimicrobial agents are very well known. This review elaborates synthesis methods and antimicrobial mechanisms of various metal as well as metal oxide nanoparticles for better understanding in order to utilize their potentials in various biomedical applications.


2015 ◽  
Vol 18 (3) ◽  
pp. 170-180
Author(s):  
Anh Thi Tram Tu ◽  
Huy Thuc Ha

Highly deacetylated chitosan (CS) reacted with anhydride acetic (Ac2O) to produce chitosan with various degree of deacetylation (DDA) depending on the CS/Ac2O ratios. The structure of products was characterized by FT-IR, 1H NMR, 13C NMR, and the molecular weight was identified by GPC. The DDA of products decreases as the CS/Ac2O ratio increases. The products with less than 80 % DDA were soluble in water with a wide pH range. The water-soluble chitosan can be used in many biomedical applications such as manufacturing drug delivery systems or functionalized iron oxide nanoparticles.


2014 ◽  
Vol 11 (2) ◽  
pp. 139-149 ◽  
Author(s):  
Denisa Ficai ◽  
Ovidiu Oprea ◽  
Anton Ficai ◽  
Alina Holban

2019 ◽  
Vol 5 (4) ◽  
pp. 60 ◽  
Author(s):  
Carbonaro ◽  
Corpino ◽  
Salis ◽  
Mocci ◽  
Thakkar ◽  
...  

The emission properties of carbon dots (CDs) have already found many potential applications, from bio-imaging and cell labelling, to optical imaging and drug delivery, and are largely investigated in technological fields, such as lighting and photonics. Besides their high efficiency emission, CDs are also virtually nontoxic and can be prepared through many green chemistry routes. Despite these important features, the very origin of their luminescence is still debated. In this paper, we present an overview of sounding data and the main models proposed to explain the emission properties of CDs and their tunability.


Polymers ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 2825
Author(s):  
Kaja Kupnik ◽  
Mateja Primožič ◽  
Vanja Kokol ◽  
Maja Leitgeb

In recent years, nanocellulose (NC) has also attracted a great deal of attention in drug delivery systems due to its unique physical properties, specific surface area, low risk of cytotoxicity, and excellent biological properties. This review is focused on nanocellulose based systems acting as carriers to be used in drug or antimicrobial delivery by providing different but controlled and sustained release of drugs or antimicrobial agents, respectively, thus showing potential for different routes of applications and administration. Microorganisms are increasingly resistant to antibiotics, and because, generally, the used metal or metal oxide nanoparticles at some concentration have toxic effects, more research has focused on finding biocompatible antimicrobial agents that have been obtained from natural sources. Our review contains the latest research from the last five years that tested nanocellulose-based materials in the field of drug delivery and antimicrobial activity.


2021 ◽  
Vol 8 (10) ◽  
pp. 134
Author(s):  
Abdulkader Baki ◽  
Frank Wiekhorst ◽  
Regina Bleul

Magnetic iron oxide nanoparticles (MNPs) have been developed and applied for a broad range of biomedical applications, such as diagnostic imaging, magnetic fluid hyperthermia, targeted drug delivery, gene therapy and tissue repair. As one key element, reproducible synthesis routes of MNPs are capable of controlling and adjusting structure, size, shape and magnetic properties are mandatory. In this review, we discuss advanced methods for engineering and utilizing MNPs, such as continuous synthesis approaches using microtechnologies and the biosynthesis of magnetosomes, biotechnological synthesized iron oxide nanoparticles from bacteria. We compare the technologies and resulting MNPs with conventional synthetic routes. Prominent biomedical applications of the MNPs such as diagnostic imaging, magnetic fluid hyperthermia, targeted drug delivery and magnetic actuation in micro/nanorobots will be presented.


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