Small Intestinal Tumors

Author(s):  
SM Sharma

ABSTRACT Small intestinal tumors are rare despite small gut being a long structure with extensive mucosal surface. The clinical presentation is vague and the existence of tumor is detected after specific investigations. Small gut can be benign or may be malignant. Malignant tumors present with abdominal pain, weight loss, anemia, obstructive features, abdominal lump, diarrhea, intussusception and even fever depending upon the type of lesion. Malignancy occurs generally in elderly group above 60 years; however, younger patients too may be affected. Benign lesions may remain asymptomatic for long till these cause complications like intussusception or obstruction. Early detection and appropriate intervention can avoid morbidity and mortality. How to cite this article Sharma SM. Small Intestinal Tumors. Int J Adv Integ Med Sci 2016;1(1):9-12.

Chemotherapy ◽  
2020 ◽  
Vol 65 (3-4) ◽  
pp. 65-76
Author(s):  
Efstratios Koutroumpakis ◽  
Nicolas L. Palaskas ◽  
Steven H. Lin ◽  
Jun-ichi Abe ◽  
Zhongxing Liao ◽  
...  

Despite the advancements of modern radiotherapy, radiation-induced heart disease remains a common cause of morbidity and mortality amongst cancer survivors. This review outlines the basic mechanism, clinical presentation, risk stratification, early detection, possible mitigation, and treatment of this condition.


Author(s):  
Philippe Ducrotté ◽  
Philippe Chassagne

The clinical challenge of recognizing then treating malabsorption is crucial in older patients, in whom the consequences in terms of both morbidity and mortality are more severe. This challenge is reinforced by a frequent atypical clinical presentation delaying the diagnosis in many cases. Indeed, as in many diseases that occur in old patients, symptoms such as weight loss are often considered to be related to altered appetite or increased catabolism rather than to malabsorption. We now have substantial evidence that malabsorption in older people should not be ascribed to the ageing process and should be evaluated in the same way as malabsorption occurring in younger patients. In an older patient, there may be several contributory causes.


2020 ◽  
Vol 7 (3) ◽  
pp. 757
Author(s):  
Sudhir R. Jayakar ◽  
Prashant V. Male ◽  
Maitreyee M. Save ◽  
Varun S. Shetty

Background: The abdominal cavity can harbour a varied spectrum of diseases. Abdominal lumps are one of the commonest disorders in this region. The clinical presentation, diagnosis, minimal investigations and optimum treatment of the lumps in the right hypochondrium were studied in detail in present study.Methods: The prospective observational study was carried out for 24 months. 60 consecutive patients who satisfied the inclusion criteria were taken up for the study. Calculation and analysis of data was done by using MS Excel.Results: The lumps in the right hypochondrium were most common in the 31-40 years age group in the present study. Majority of the lumps were found to be intraperitoneal (65%), of which 45% were neoplastic in nature. 68.3% as compared to 31.7% of lumps had an organ of origin which was not anatomically situated in the right hypochondrium viz. from right kidney and right adrenal. Hepatic lumps were found to be the commonest (35%), of which 14.3% were malignant tumors. Gall bladder carcinoma was more common in 40-60 years with female preponderance. Only 26.7% patients presented with the complaint of lump in abdomen. The commonest complaint was pain in the abdomen followed by vomiting. In 88.3% cases surgery was undertaken for curative or palliative purposes.Conclusions: Of all the lumps in the right hypochondrium, intraperitoneal lumps were more common with abdominal pain as commonest presenting symptom. The commonest lumps were found to be hepatic lumps. Incidence of Neoplastic masses was more than infections and infestations.


2018 ◽  
Vol 5 (10) ◽  
pp. 3288
Author(s):  
Anil Balraj T. ◽  
S. Srinivas ◽  
K. Ramesh Reddy ◽  
Manisha Reddy G. ◽  
Anusiri Inugala

Background: Intestinal malrotation is a congenital anomaly that results from abnormal or incomplete rotation and fixation of midgut during embryonic development. This study was done at Niloufer Hospital and Institute for Women and Child Health, Hyderabad with an aim of evaluating the clinical presentation, diagnosis, management and outcome of malrotation presenting beyond 1 year of lifeMethods: Overall 50 cases of malrotation presented to the department of pediatric surgery over a period of 2 year (April 2015 to April 2017). 12 patients of these 50 (12/50) whose age was above 1 year i.e. who were beyond infancy were studied in this studyResults: Out of the 12 patients, 6 were female and 6 were male. Age of patients ranged from 15 months to 13 years. Younger patients below 2 years commonly presented with typical symptoms of bilious vomiting and patients above 2 years of age presented with more varied and vague symptoms. 1/12 of patients presented with a poor general condition and succumbed during the course of treatmentConclusion: Small intestinal obstruction due to malrotation is relatively common in neonatal period. Malrotation beyond infancy is an uncommon diagnosis. Malrotation in grown up children usually is not suspected due to varied symptoms. High index of suspicion is needed as early intervention and treatment in the form of Ladds procedure can prevent any catastrophic events like volvulus and bowel ischemia.


2021 ◽  
Vol 14 (1) ◽  
pp. 14-18
Author(s):  
Subash Bhattarai ◽  
Om Bahadur Karki ◽  
Merina Gyawali ◽  
Sudeep Regmi

Introduction: Colorectal cancer is the most common malignancy of the gastrointestinal tract. They are common after 50 years of age and present with bleeding per rectum, altered bowel habits, anemia, pain abdomen, and weight loss. The objective of this study was to evaluate the demographic profile, clinical presentation, colonoscopy and histopathology findings of colorectal cancer. Methods: A descriptive cross-sectional study was conducted. Cases were studied from the departmental records. Clinical presentation, CT abdomen, colonoscopy, and histopathology findings of colorectal carcinoma were studied. Data entry was done in SPSS version 20. Results: The mean age of subjects was 56 ± 11.42 years (range of 34 – 80 years) with male predominance (M: F=3:2). Changes in bowel habits (92.3%), chronic abdominal pain (84.6%), generalized weakness (80.7%), rectal bleeding (46.2%), and significant weight loss (42.3%) were the most common presenting symptoms. Rectal carcinoma was the most common (35%) followed by carcinomas of ascending colon (14%) and descending colon (10 %). The most common morphology was proliferative growth (61.5%). All colorectal carcinomas were adenocarcinoma, and the majority was moderately differentiated (51.9%). Conclusion: Colorectal cancers are seen above 50 years of age and common in males. Changes in bowel habits, chronic abdominal pain, generalized weakness, rectal bleeding, and weight loss are the most common form of presentations. These patients usually present late with advanced disease and unfavorable histopathology. Screening colonoscopy >50 years is strongly recommended.


2021 ◽  
pp. 140-141
Author(s):  
Fabricio Andrés Lasso Andrade ◽  
Jorge Alejandro Cadena Arteaga ◽  
Denny Marcela Achicanoy Puchana ◽  
Thanya Mariselle Lagos ◽  
Hermes Albeiro Ortega Díaz ◽  
...  

Solid pseudopapillary neoplasms (SPN) of the pancreas are rare tumors, occurring in 1-2% of all pancreatic neoplasms; of these 10 to 15% have an aggressive presentation. Most of the patients present disease localized to the pancreas, however, between 9-15% may present local invasion and metastasis. The clinical presentation in the vast majority of SPN is asymptomatic, even despite a large tumor size. We present a case of a 16-year-old female patient with a psedupapillary tumor of the pancreas (Frantz tumor) who was admitted due to abdominal pain and weight loss lasting 3 months.


2002 ◽  
Vol 13 (4) ◽  
pp. 1-11 ◽  
Author(s):  
Ketan R. Bulsara ◽  
Takanori Fukushima ◽  
Allan H. Friedman

As the management of anterior cranial fossa malignancies has undergone significant evolution, decreases in morbidity and mortality rates have occurred. In this article, the authors discuss the clinical presentation, neuroimaging findings, and management options for common anterior skull base malignancies. Also discussed are surgery-related indications and principles.


2021 ◽  
Vol 2021 (3) ◽  
Author(s):  
Rafaela Parreira ◽  
Tiago Rama ◽  
Teresa Eloi ◽  
Vítor Carneiro ◽  
Maria Inês Leite

Abstract Gastric lipomas are rare, representing 2–3% of all benign tumours of the stomach. Most of these stomach neoplasms are small and detected incidentally during endoscopic or radiology evaluations. Computed tomography is highly specific imaging for lipoma diagnosis. Endoscopy and endoscopic ultrasound are other important diagnostic modalities to confirm the diagnosis. Identifying typical features can avoid biopsy or surgery in asymptomatic patients. In patients with larger lesions, usually more than 2 cm, clinical presentation may encompass haemorrhage, abdominal pain, pyloric obstruction and dyspepsia. As a result of its extreme low incidence, treatment is not standardized, though it is widely accepted that a symptomatic tumour mandates resection. Here, we present the case of a 60-year-old female presenting with abdominal pain and recurrent vomiting due to a giant gastric lipoma (80 × 35 × 35 mm). The patient underwent laparotomy and an enucleation was performed.


2021 ◽  
pp. 1-10
Author(s):  
Bipasha Roy ◽  
Shari R. Lipner

Acrokeratosis paraneoplastica (Bazex syndrome) is a rare paraneoplastic dermatosis associated with internal malignancies. Clinical presentation is characterized by erythematous or violaceous scaly plaques involving the digits, nose, ears, palms, and soles. Nail changes commonly present concurrently with cutaneous manifestations. In this review, we characterize nail changes associated with acrokeratosis paraneoplastica. A total of 48 cases were analyzed. Nail findings were nonspecific, with the most common being nail plate thickening, onycholysis, subungual hyperkeratosis, longitudinal ridging, discoloration, and nail plate loss. In most patients, nail changes involved the majority of fingernails and toenails and most often appeared prior to the diagnosis of malignancy. The most common associated underlying malignancies were squamous cell carcinomas of the head and neck. A diagnosis of acrokeratosis paraneoplastica should be considered in patients with onychodystrophy involving multiple nails with accompanying atypical psoriasiform dermatoses. Screening for internal malignancies may significantly decrease morbidity and mortality for these patients.


2021 ◽  
pp. 538-544
Author(s):  
Nozomi Karakuchi ◽  
Senichiro Yanagawa ◽  
Kei Kushitani ◽  
Shinya Kodama ◽  
Yukio Takeshima ◽  
...  

Sarcomatoid carcinoma (SC) is a rare malignant tumor with properties of both epithelial and mesenchymal carcinomas. SC has been reported in various organs, but the number of reports for each type is small. Small intestinal tumors make up about 3–6% of gastrointestinal malignancies. Discovering them in the early stage is rare and difficult, with anemia and/or abdominal pain as the major symptoms of small intestinal tumors. Primary small intestinal SC (SISC) is rare among small intestinal tumors, and currently very few cases have been reported in the literature. Previous studies have reported that neither chemotherapy nor radiotherapy improves the overall survival rate of patients with SISC, and the prognosis is extremely poor. Currently, surgical resection remains the only optimal therapeutic approach for SISC. Here, we present the case of a 90-year-old woman who had acute peritonitis due to perforation of a small intestinal tumor. She underwent emergency exploratory laparotomy and partial resection of the small intestine, including the tumor. The tumor was pathologically identified as a primary SISC with mesenteric lymph node metastasis. Subsequently, she had recurrence in the intra-abdominal area and lymph node metastasis anterior to the inferior vena cava and died 15 months after surgery without any additional treatment.


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