scholarly journals A case series on pulmonary and tissue aspergillosis

Biomedicine ◽  
2021 ◽  
Vol 41 (2) ◽  
pp. 324-327
Author(s):  
S Lokesh ◽  
R Prabha ◽  
S Pramodhini ◽  
J.M. Easow
Keyword(s):  
Early Diagnosis ◽  
Invasive Aspergillosis ◽  
Past History ◽  
Allergic Bronchopulmonary Aspergillosis ◽  
Case Series ◽  
Opportunistic Pathogen ◽  
Good Prognosis ◽  
Incidence And Mortality ◽  
Male Preponderance ◽  
Immunosuppressed Patients

Aspergilli species cause opportunistic fungal infection in immunocompromised individuals. Invasive aspergillosis is a highly fatal opportunistic infection that accounts for amajor risk to immunocompromised patients. Among these species, A.fumigatus is the main opportunistic pathogen followed by A.niger and A.flavus. In immunocompetent individuals, the effective innate immunity eliminates theinhaled conidia and Allergic bronchopulmonary aspergillosis and aspergilloma are the only infections noted in them. Thus,A.fumigatus was considered for years to beainfirm pathogen. With increase in the number of immunosuppressed patients, however, there has been a marked increase in fatal invasive aspergillosis, which is now the widespread mold infection. In this case series, we have described four cases of aspergillosis. Male preponderance is seen, commonly seen in 4th to 5th decade, 3 out of 4 cases are immunocompromised having diabetes, chronic kidney disease, past history of tuberculosis and only one case was not associated with any comorbid illness. In case 4, the recurrence of polypoidalsinosis itself could be a risk factor causing erosion of nasal mucosa and chronic secretion.The morphological features of intraluminal lesions were of prognostic value. Most of the Aspergillosis patients had a good prognosis with early diagnosis and effective antifungal therapy.It can bedeadly if not diagnosed and treated properly.Very rarely aspergillosis may occur in immunocompetent individuals, which urged us to point outthese cases. With studies suggesting surging incidence and mortality rates, early diagnosis and treatment are paramount to upgrade patient survival.

scholarly journals Total unilateral pulmonary collapse secondary to allergic bronchopulmonary aspergillosis: a case series of an unusual cause of complete atelectasis

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
N. Benkalfate ◽  
S. Dirou ◽  
P. Germaud ◽  
C. Defrance ◽  
A. Cavailles ◽  
...  
Keyword(s):  
Past History ◽  
Allergic Bronchopulmonary Aspergillosis ◽  
Case Series ◽  
Chronic Respiratory Disease ◽  
Flexible Bronchoscopy ◽  
Respiratory Disorder ◽  
Lung Collapse ◽  
Radiographic Findings ◽  
Case Presentation ◽  
History Of

Abstract Background Allergic bronchopulmonary aspergillosis (ABPA) is a bronchopulmonary disease caused by a complex hypersensitivity to Aspergillus and is usually associated with underlying respiratory diseases such as asthma or cystic fibrosis. Mucus plugging can lead to segmental or lobar atelectasis, but complete lung atelectasis has been exceptionally reported in the literature, making it difficult to diagnose. The diagnosis of ABPA may however be suggested in patients without known predisposing respiratory disorder, even in the absence of other relevant radiographic findings. Case presentation We report five cases of total unilateral lung collapse secondary to ABPA in 70–81-year-old women. Two of them had a past history of ABPA, while total unilateral lung collapse was the first sign of the disease in the other three patients, contributing to the initial misdiagnosis. Flexible bronchoscopy was initially performed to remove mucus plugs from the obstructed airways but was inefficient in four cases. Corticosteroid and/or antifungal treatment was needed. Conclusion ABPA can cause total unilateral lung collapse even in patients without known underlying chronic respiratory disease, making the diagnosis difficult. Flexible bronchoscopy should be considered when lung collapse is associated with respiratory distress but corticosteroids are the mainstay treatment for ABPA.

UPDATE ON THE DIAGNOSIS AND MANAGEMENT OF EARLY GASTRIC CANCER

2015 ◽  
pp. 5-14
Author(s):  
Van Huy Tran ◽  
Quang Trung Tran
Keyword(s):  
Gastric Cancer ◽  
Early Gastric Cancer ◽  
Early Diagnosis ◽  
Cancer Diagnosis ◽  
Good Prognosis ◽  
Accurate Diagnosis ◽  
White Light Endoscopy ◽  
Key Factor ◽  
Magnified Endoscopy ◽  
Endoscopic Characteristics

The prognosis of gastric cancer depends principally upon an early diagnosis. An early and accurate diagnosis of gastric cancer needs some basic knowledges about the endoscopic characteristics of white light endoscopy, chromoendoscopy, magnified endoscopy, FICE and NBI…A strategy of screening is also a key factor for early diagnosis. The treatment of early gastric cancer by endoscopy techniques have showed more and more advantages. Beside of EMR, the technique of ESD is now applied more widely and lead to a very good prognosis and nearly a curative treatment for the patients with early gastric cancer. Key words: gastric cancer, early gastric cancer, diagnosis, endoscopy

Therapy of invasive aspergillosis with itraconazole: improvement of therapeutic efficacy by early diagnosis

Mycoses ◽  
2009 ◽  
Vol 34 (9-10) ◽  
pp. 385-394 ◽  
Author(s):  
W. Kreisel ◽  
G. Kochling ◽  
C. v. Schilling ◽  
M. Azemar ◽  
Beatrix Kurzweil ◽  
...  
Keyword(s):  
Early Diagnosis ◽  
Invasive Aspergillosis ◽  
Therapeutic Efficacy

Invasive aspergillosis in immunosuppressed patients

BMJ ◽  
1990 ◽  
Vol 301 (6759) ◽  
pp. 1046-1047 ◽  
Author(s):  
M L Shields ◽  
M V Joyner ◽  
R Lee
Keyword(s):  
Invasive Aspergillosis ◽  
Immunosuppressed Patients

Orthodontic management of impacted mandibular second molars: A case series

2021 ◽  
Vol 14 (2) ◽  
pp. 98-104
Author(s):  
Andrea Cunningham ◽  
Dipali Patel ◽  
Zahra Sheriteh
Keyword(s):  
Early Diagnosis ◽  
Clinical Relevance ◽  
Case Series ◽  
Diagnosis And Treatment ◽  
Treatment Modalities ◽  
Individual Basis ◽  
Diagnosis And Management

This case series describes a number of different treatment modalities used in the management of impacted mandibular second molars (MM2s). A variety of cases is used to illustrate a number of ways in which these teeth can be managed, and to demonstrate that each case should be managed on an individual basis, taking into account the overall malocclusion. The importance of early diagnosis and management is highlighted throughout. CPD/Clinical Relevance: This case series highlights the difficulties and challenges in managing patients who present with impacted lower second molars (MM2s), and the importance of early diagnosis and treatment.

scholarly journals Growing Menace of Antibacterial Resistance in Clinical Isolates ofPseudomonas aeruginosain Nepal: An Insight of Beta-Lactamase Production

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Shamshul Ansari ◽  
Rabindra Dhital ◽  
Sony Shrestha ◽  
Sangita Thapa ◽  
Ram Puri ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Antibiotic Resistance ◽  
Opportunistic Pathogen ◽  
Resistance Rate ◽  
Diffusion Method ◽  
Beta Lactamase ◽  
Beta Lactam ◽  
Beta Lactam Antibiotics ◽  
Microbiological Methods ◽  
Immunosuppressed Patients

Introduction. Pseudomonas aeruginosais the most frequently isolated organism as it acts as the opportunistic pathogen and can cause infections in immunosuppressed patients. The production of different types of beta-lactamases renders this organism resistant to many commonly used antimicrobials. Therefore, the aim of this study was to document the antibiotic resistance rate inPseudomonas aeruginosaisolated from different clinical specimens.Methods. Pseudomonas aeruginosarecovered was identified by standard microbiological methods. Antibiotic susceptibility testing was performed by modified Kirby-Bauer disc diffusion method following Clinical and Laboratory Standard Institute (CLSI) guidelines and all the suspected isolates were tested for the production of ESBLs, MBLs, and AmpC.Results.Out of total (178) isolates, 83.1% were recovered from the inpatient department (IPD). Majority of the isolates mediated resistance towards the beta-lactam antibiotics, while nearly half of the isolates were resistant to ciprofloxacin. Most of the aminoglycosides used showed resistance rate up to 75% but amikacin proved to be better option. No resistance to polymyxin was observed. ESBLs, MBLs, and AmpC mediated resistance was seen in 33.1%, 30.9%, and 15.7% isolates, respectively.Conclusions. Antibiotic resistance rate and beta-lactamase mediated resistance were high. Thus, regular surveillance of drug resistance is of utmost importance.

scholarly journals Clinically Suspected Myocarditis in COVID-19 Patients: Case Series and Review of Literature

2021 ◽  
Author(s):  
Ahmad Amin ◽  
Seyed Parsa Eftekhar ◽  
Naghmeh Ziaei ◽  
Soudeh Roudbari ◽  
Pegah Salehi ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Left Ventricle ◽  
Ejection Fraction ◽  
Case Series ◽  
Female Gender ◽  
Good Prognosis ◽  
Left Ventricle Ejection Fraction ◽  
Review Of Literature ◽  
Younger Age ◽  
Poor Outcomes

We described eleven patients positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The younger age and female gender seem to contribute to poor outcomes possibly. Furthermore, the left ventricle ejection fraction and pro-BNP improvement within the first week of treatment might indicate a good prognosis.

scholarly journals Tracheo-bronchial foreign bodies: our experience at a tertiary care hospital

2016 ◽  
Author(s):  
Shashidhar S. Suligavi ◽  
Mallikarjun N. Patil ◽  
S. S. Doddamani ◽  
Chandrashekarayya S. Hiremath ◽  
Afshan Fathima
Keyword(s):  
Foreign Body ◽  
Early Diagnosis ◽  
Foreign Bodies ◽  
Tertiary Care ◽  
Case Series ◽  
Team Work ◽  
Care Hospital ◽  
Retrospective Case ◽  
Presenting Symptoms ◽  
Case Series Study

<p class="abstract"><strong><span lang="EN-US">Background:</span></strong>Tracheo- bronchial foreign bodies have always posed a challenge to the ENT surgeon as they present with varied symptomatology ranging from a simple cough and fever to more grave respiratory distress. It requires a strong suspicion, early diagnosis and timely intervention to reduce the overall morbidity and mortality .This study was undertaken to highlight our experiences in handling cases of tracheo- bronchial foreign bodies (FB) at our setup.</p><p class="abstract"><strong><span lang="EN-US">Methods:</span></strong>It is a retrospective case series study conducted in S. Nijalingappa Medical College between January 2011 and January 2015.  </p><p class="abstract"><strong><span lang="EN-US">Results:</span></strong>Most commonly affected were children between 1year to 3years of age. Chronic cough and wheeze were the commonest presenting symptoms. Vegetative foreign body was found to be the commonest variety of foreign body. The mortality rate in our study was 4.7% (n=3).</p><p class="abstract"><strong><span lang="EN-US">Conclusions:</span></strong>A good clinical acumen, team work, early diagnosis and timely intervention are all needed to reduce the overall mortality and morbidity associated with tracheo- bronchial foreign bodies.</p>

scholarly journals Effect of Placenta Previa on fetal & maternal morbidity / mortality

2016 ◽  
Vol 11 (3) ◽  
Author(s):  
Bushra Sehr Zaman ◽  
Asma Zubair ◽  
Sher Zaman Bhatti ◽  
Muhammad Zubair Saeed Malik
Keyword(s):  
Risk Factors ◽  
Early Diagnosis ◽  
Maternal Morbidity ◽  
Placenta Previa ◽  
Case Series ◽  
Antenatal Clinic ◽  
Case Series Study ◽  
Severe Hemorrhage ◽  
Year 2000 ◽  
Series Study

Objective: To see the effect of placenta previa on fetal and maternal mortality/ morbidity. This was a case series study. Study was conducted in Gynecology unit BV Hospital Bahawalpur during year 2000 to 2003. All the patients presenting with or with out painless bleeding in antenatal clinic & proved to be due placenta previa were included in the study. Patients presenting with pain less bleeding in the antenatal clinic due to other reasons were excluded from the study. In all the patients` history along with the risk factors clinical and sonography finding, any intervention needed and final out come was recorded. SPSS was used for data collection & analysis. Results: Total 50 patients were studied Out of these 84% of patients were symptomatic a t admission the symptoms found were Bleeding, shock & Pain. Strong associations o f risk factors like Age, Parity, ERCP, Smoking and previous C. Section was found in our study. Severe hemorrhage, prematurity, stillbirths and ENND was associated with Placenta Previa. Conclusion: Placenta previa is not an uncommon but underestimated, under reported & preventable condition. Prevention is possible in case of Known risk factors. Early diagnosis is necessary as the delay in some cases may end up in disaster

Sign in / Sign up

Export Citation Format

Share Document