scholarly journals Use of biotherapic in the control of the natural infestation by Boophilus microplus: pilot study

2021 ◽  
Vol 7 (22) ◽  
pp. 36-38
Author(s):  
Alessandro Pelegrine Minho ◽  
Nilceu Lemos Silva ◽  
José Luiz Moletta ◽  
Laerte Francisco Filippsen
Keyword(s):  
Pilot Study ◽  
Boophilus Microplus ◽  
Control Group ◽  
Group Iii ◽  
Commercial Mixture ◽  
Palabras Clave ◽  
Significant Difference ◽  
Alternative Procedures ◽  
Tick Borne Disease ◽  
Natural Infestation

In the control of tick-borne disease (TBD), resistance to chemical products has been reported and a concern with the preservation of the environment requires alternative procedures to control infestation by Boophilus microplus worldwide. The use of biotherapic preparations is one of such alternatives. The aim of this study was to evaluate the effects of a biotherapic mixture including B. microplus in naturally infested cattle. 27 animals were divided in 3 groups (n=9): I – control, received no treatment; II- treated with amitraz dip; III- treated with a standard commercial mixture of biotherapic 12cH, p.o. Group III presented a statistically significant decrease of ticks when compared to the control group (p < 0.05). There was no statistically significant difference between groups II (amitraz) and III (biotherapic) (p < 0.05). These results suggest that biotherapic preparations might be effective in the control of B. microplus in cattle. Keywords: Biotherapic; Tick; Alternative control; Cattle.   Uso do bioterapico no controle da infestação natural por Boophilus microplus: estudo piloto Resumo No controle de enfermidades transmitidas por carrapatos tem sido notada a resisténcia a produtos químicos. A preocupação com a conservação do meio ambiente tem exigido procedimentos alternativos para controlar a infestação por Boophilus microplus, em todo o mundo. O uso de bioterápicos representa uma dessas alternativas. O objetivo deste estudo foi avaliar o efeito de uma mistura de bioterápicos incluindo B. microplus, em gado bovino infestado naturalmente. 27 animais foram divididos em 3 grupos (n=9): I) controle sem tratamento; II) tratado com banho de amitraz; III) tratado com mistura comercial de bioterápicos 12 cH, via oral. O grupo III apresentou uma diminuição estatísticamente significativa de carrapatos, em comparação com grupo controle (p < 0,05). Não houve diferença significativa entre os grupo II e III (p < 0,05). Estes resultados sugerem que os preparados de bioterápicos podem ser eficazes para o controle de B. microplus em bovinos. Palavras-chave: Bioterapicos; Carrapato; Controles alternativos; Bovinos.   Uso de bioterápico en el control de la infestación natural por Boophilus microplus: estudio piloto Resumen En el control de enfermedades trasmitidas por garrapatas, ha sido notada resistencia los productos químicos; la preocupación con la conservación del ambiente exige procedimientos alternativos para controlar la infestación por Boophilus microplus mundialmente. El uso de preparados bioterápicos representa una de esas alternativas. El objetivo de este estudio fue evaluar el efecto de una mezcla bioterápica incluyendo B. microplus en ganado infestado naturalmente. 27 animales fueron divididos en 3 grupos (n=9): I) control, sin tratamiento; II) tratado con banho de amitraz; III) tratado con mezcla comercial de bioterápicos 12cH, vía oral. El grupo III presentó una disminución estadísticamente significativa de garrapatas en comparación al grupo control (p < 0,05). No hubo diferencia significativa entre los grupos II y III (p < 0,05). Estos resultados sugieren que los preparados de bioterápicos pueden ser eficaces para controlar B. microplus en ganado. Palabras-clave: Bioterapicos; Garrapatas; control alternativo; Ganado.   Correspondence author: Alessandro P. Minho. [email protected]; http://www.iapar.br; Instituto Agronômico do Paraná (IAPAR)-PR, Brazil. How to cite this article: Silva NL, Moletta JL, Minho AP, Filippsen LF. Use of biotherapic in the control of natural infestation by Boophilus microplus: pilot study. Int J High Dilution Res [online]. 2008 [cited DD Mmm YYYY]; 7 (22): 36-38. Available from http://journal.giri-society.org/index.php/ijhdr/article/view/251/337.  

The Effect of Reflexology on Lactation in Women Who Had Cesarean Section: A Randomized Controlled Pilot Study

2021 ◽  
pp. 1-8
Author(s):  
Sevde Aksu ◽  
Pelin Palas Karaca
Keyword(s):  
Pilot Study ◽  
Cesarean Section ◽  
Intervention Group ◽  
Control Group ◽  
Breast Pain ◽  
Randomized Controlled ◽  
Significant Difference ◽  
The Right ◽  
Documentation Tool ◽  
And Control

<b><i>Aim:</i></b> The research was conducted as a randomized controlled pilot study to evaluate the effects of reflexology on lactation in mothers who delivered by cesarean section (CS). <b><i>Methods:</i></b> A single-blind randomized controlled experimental study was conducted with a total of 60 postpartum women in the reflexology application (<i>n</i> = 30) and control groups (<i>n</i> = 30). After the CS, the mothers in the control group were given approximately 3-h routine nursing care after recovering from the effects of anesthesia; the introductory information form was applied, and the Breastfeeding Charting System and Documentation Tool (LATCH) and visual analog scale (VAS) for the signs of the onset of lactation were implemented on the first and second days. Reflexology was applied to the women in the intervention group after an average of 3 h following the mother’s condition had become stable and she had recovered from the effects of anesthesia. Reflexology was applied a total of 20 min – 10 min for the right foot, 10 min for the left foot – twice a day with 8-h intervals on the first and second days after CS. After the last reflexology application, the LATCH and VAS for the signs of the onset of lactation were applied. <b><i>Results:</i></b> Of the women, 70% breastfed their babies within 60 min after delivery; 46.7% of the mothers received breastfeeding training and 81.7% needed support for breastfeeding after the CS. The LATCH breastfeeding scores of the women in the intervention group on both days were significantly higher compared to those of the women in the control group (<i>p</i> &#x3c; 0.001). On the first day after the CS, apart from breast pain, there was no significant difference between the two groups in terms of breast heat and breast tension (<i>p</i> &#x3e; 0.05). On the second day after the CS, apart from breast tension, there was no significant difference between the groups in terms of breast heat and breast pain (<i>p</i> &#x3c; 0.05). In the study, women in the intervention group were found to have higher scores in terms of all three symptoms compared to the control group (<i>p</i> &#x3c; 0.05). <b><i>Conclusions:</i></b> In the study, it was determined that LATCH scores and signs of the onset of breastfeeding increased in the mothers who received reflexology after CS.

Impact of supplementing commercial rabbit pellets with fresh Moringa oleifera leaves on semen characteristics in rabbit bucks under tropical climate in Trinidad

2021 ◽  
Author(s):  
Krishna Mohan Kumar
Keyword(s):  
Sperm Motility ◽  
Moringa Oleifera ◽  
Sperm Count ◽  
Control Group ◽  
Computer Assisted ◽  
Group Iii ◽  
Group I ◽  
Significant Difference ◽  
Moringa Oleifera Leaves ◽  
The Impact

Objective This study aimed to evaluate the impact of the dietary supplement of Moringa oleifera leaves (MOL) on semen quality and characteristics in rabbits. Methods Eighteen (n=18) breeding bucks of New Zealand white, of similar age group, were used for the study. Three feeding regimes, (i) 100% commercial rabbit pellets (CRP)-Group I (ii) 90% CRP + 10% fresh MOL on a dry matter (DM) basis – Group II and (iii) 80% CRP + 20% fresh MOL on a DM basis – Group III, were adopted and the trial continued for 21 days. After adaptation to the diet, semen was collected from each buck and subjected to evaluation using a computer-assisted semen analyser. Results In Group III, the sperm count, normal sperm morphology, and sperm motility increased (52.0%) in comparison with the control (Group I; 50.1%). The inclusion of 20% Moringa oliefera in the diet (Group III) caused a significant increase (P<0.05) in semen concentration (Control =136.2 M/mL; Group III=297.2 M/mL). There was no significant difference (P>0.05) in sperm motility and semen volume among the groups. Conclusion The results suggest that supplementing commercial rabbit pellets with 20% fresh Moringa oliefera leaves on a DM basis can improve the quality and characteristics of semen in breeding bucks.

scholarly journals Effects of nano mineral-supplemented diet on sow productivity

2019 ◽  
Vol 41 (4) ◽  
Author(s):  
Hoang Nghia Son
Keyword(s):  
Birth Weight ◽  
Reproductive Performance ◽  
Metal Content ◽  
Mineral Content ◽  
Control Group ◽  
Average Weight ◽  
Group Iii ◽  
Newborn Piglets ◽  
Group I ◽  
Significant Difference

This study aimed to evaluate the effects of nano mineral-supplemented diet on sow productivity. The data were estimated by several parameters consisting of piglet live ratio at newborn stage and weaning stage, piglet weight at newborn stage and weaning stage, metal content in piglet livers. The results showed that live ratio of newborn piglets in group III was highest (93.44 ± 2.83%) comparing with other groups. However, there was no significant difference of live ratio in piglets at weaning stage between nano mineral-supplemented groups with control. The birth weight of piglets in nano mineral-supplemented groups was similar to control group. The birth weight of piglets in nano mineral-supplemented groups was ranged from 1,361.61 ± 47.37 grams (group II) to 1,410.48 ± 44.28 grams (group I). However, the average weight of weaned pigs in groups III and IV was higher than other groups (6,772.92 ± 105.47 grams and 6,818.87 ± 89.59 grams). Moreover, the amount of Fe, Cu, Zn, Mn in piglet liver from nano mineral-supplemented groups have been found to be lower than those in control group. These results revealed that the supplement of nano minerals for sows promoted the reproductive performance of sows and reduced mineral content in the liver of piglets. 

scholarly journals Oral Hygiene in a Sample of Children/Adolescents Living in Family-Homes from the Province of Milan (Italy): A Pilot Study

2020 ◽  
Vol 8 (2) ◽  
pp. 33 ◽  
Author(s):  
Alessandro Nota ◽  
Floriana Bosco ◽  
Shideh Ehsani ◽  
Francesca Giugliano ◽  
Giulia Moreo ◽  
...  
Keyword(s):  
Pilot Study ◽  
Oral Hygiene ◽  
Clinical Results ◽  
Plaque Index ◽  
Control Group ◽  
Controlled Clinical Trial ◽  
Study Group ◽  
Significant Difference ◽  
And Gender ◽  
Oral Hygiene Instructions

Objective: This pilot study is a prospective controlled clinical trial, designed to evaluate the short-term clinical results (the plaque index) of an educational/motivational program for home oral hygiene, directed to children and adolescents who live in family-homes. Methods: The setting of the project was the province of Milan (Italy), where two family-homes were selected. The study group included 26 children (16 females and 10 males) aged between 7 and 15 years, of Italian nationality, from the family-home communities. The control group included 26 children (15 females and 11 males, aged between 7 and 15 years) of Italian nationality, matched for age and gender distribution with the study group, that were not in a socially disadvantaged condition. Collection of the plaque index (PI) was performed at t0. Then, all basic oral hygiene instructions were given to all children/adolescents and their educators. Education and motivation were repeated in the same way after 4–7 weeks (T1), and after 10–12 weeks (T2). The PI was taken also at T1 and T2. Results: An improvement in the PI was generally found in both groups, but there was no statistically significant difference between the two groups over time. Multivariate analysis of variance (MANOVA) revealed a statistically significant effect of time [F (1, 52) = 90.73, p < 0.001], regardless of the assignment group, in consequence of which the plaque index presented a moderate and significant improvement. Conclusion: The present data confirm the validity of the educational/motivational program to improve oral hygiene in children/adolescents, regardless of the assignment group.

Urinary Claudin-1 Level as a Marker of Podocyte Injury in Patients with Proteinuria

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
M E Nasser ◽  
S M Shawky ◽  
E A M Sanad
Keyword(s):  
Wide Spectrum ◽  
Cell Junction ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Podocyte Injury ◽  
Group Iii ◽  
Group I ◽  
Significant Difference ◽  
Diaphragm Cell ◽  
Control Study

Abstract Background The biology of claudins is a rapidly evolving field, and many intriguing questions remain unanswered. Although it had been assumed that the reason there are ≥24 isoforms of claudin is that each one has distinct permeability properties. The nephron displays a wide spectrum of claudins, whose distribution varies in each tubular segment. In diabetic nephropathy and glomerulonephritis the gene expression of claudin-1, is markedly upregulated in the podocyte, accompanied by a tighter filtration slit diaphragm (cell-cell junction made by the glomerular podocytes) and the appearance of TJ-like structures between the foot processes causing further podocytes injury and proteinuria. Aim of the work to assess urinary claudin -1 level as a marker of podocyte injury in patients with proteinuria. Patients and Methods it is a case control study which was conducted upon 90 subjects who were divided into three groups: group I included 30 patients with type II DM, group II included 30 patients with glomerulonephritis and group III had 30 healthy subjects as controls. Urinary claudin-1 level was measured by Enzyme linked Immunosorbent Assay (ELISA) Results In this study, we found that urinary claudin-1 level was significantly higher in diabetics group and GN group than in control group. In comparison between GN group and diabetic group, we found that urinary claudin-1 level was higher in GN group than in diabetics group but with no statistically significant difference between the two groups. Conclusion urinary claudin-1 level was significantly higher in diabetics and GN group and has positive correlation with uACR. So it can be used as marker of podocytes injury and proteinuria

Resistance by cattle to cattle tick, Boophilus microplus. III. The development of resistance to experimental infestations by purebred Sahiwal and Australian Illawarra Shorthorn cattle

1971 ◽  
Vol 22 (2) ◽  
pp. 331 ◽  
Author(s):  
RW Hewetson
Keyword(s):  
Adult Female ◽  
Acquired Resistance ◽  
Boophilus Microplus ◽  
Cattle Tick ◽  
Control Group ◽  
The Third ◽  
Development Of Resistance ◽  
Significant Difference ◽  
Sahiwal Cattle ◽  
Males And Females

Purebred Sahiwal cattle acquired resistance to Boophilus microplus in a similar manner to crossbred Sahiwal cattle as previously reported. The purebred entire males and females were more resistant than a control group of crossbred steers because they dropped significantly fewer replete ticks than the crossbreds at the third and fourth, but not at the first and second infestations. Adult female ticks dropped by purebred animals were significantly lighter than those dropped by crossbred animals at the fourth infestation only. There was no significant difference in the numbers of eggs laid and hatched from ticks dropped by purebred and crossbred animals. Australian Illawarra Shorthorn steers developed resistance at a second and third infestation which waned at a fourth infestation, but individual steers displayed developing resistance throughout the four infestations. Day of modal drop of replete female ticks appeared to be affected by breed, and developing resistance or season.

Vestibular rehabilitation using video gaming in adults with dizziness: a pilot study

2018 ◽  
Vol 132 (3) ◽  
pp. 202-206 ◽  
Author(s):  
J S Phillips ◽  
J Fitzgerald ◽  
D Phillis ◽  
A Underwood ◽  
I Nunney ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Trial ◽  
Pilot Study ◽  
Vestibular Rehabilitation ◽  
University Hospital ◽  
Control Group ◽  
Rehabilitation Protocol ◽  
Wii Fit ◽  
Significant Difference

AbstractObjective:To determine the effectiveness of vestibular rehabilitation using the Wii Fit balance platform, in adults with dizziness.Methods:A single-site prospective clinical trial was conducted in a university hospital in the UK. Forty patients with dizziness, who would normally be candidates for vestibular rehabilitation, were identified and considered as potential participants. Participants were randomised into either the treatment group (the Wii Fit group) or the control group (standard customised vestibular rehabilitation protocol). Participants were assessed over a 16-week period using several balance and quality of life questionnaires.Results:Both exercise regimes resulted in a reduction of dizziness and an improvement in quality of life scores over time, but no statistically significant difference between the two interventions was identified.Conclusion:This pilot study demonstrated that use of the Wii Fit balance platform resulted in a statistically significant improvement in balance function and quality of life. Furthermore, outcomes were comparable to a similar group of individuals following a standard customised vestibular rehabilitation protocol. The study provides useful information to inform the design and execution of a larger clinical trial.

The Role of sFas in the Immune Escape Mechanism and Progression of Cancer Larynx

2009 ◽  
Vol 2 ◽  
pp. CMENT.S2565
Author(s):  
Amr A El Badry ◽  
Ismail Elmofty ◽  
Amira Helmy
Keyword(s):  
Serum Level ◽  
Buffy Coat ◽  
Control Group ◽  
Group Iii ◽  
Soluble Fas ◽  
Group I ◽  
Significant Difference ◽  
Cancer Larynx ◽  
The Mean ◽  
Group Ii

This work assess serum levels of soluble Fas form (sFas) in patients with different stages of laryngeal squamous cell carcinoma(LSCC) to investigate its prognostic significance. We correlate its levels with the morphological changes of peripheral blood cells via buffy coat examinatin. The study population included 70 patients clinically diagnosed and pathohistologically confirmed LSCC in addition to 20 healthy controls. According to TNM classification 33(47.1%) patients were in stage I (group I) and 24(34.3%) in stage II (group II), 13(18.5%) in stage III (group III). The results revealed that the mean serum level of sFas (pg/ml) in the control group was 51.2, in group I was 66.33, in group II was 81.33 and in group III was 112.45. Statistical analysis of the mean of sFas by ELISA test in the patients' groups in comparison to the control revealed a significant increase of both group II and III in comparison to the control group (P < 0.01) but there was no significant difference (P > 0.05) between group I in comparison to either the control or group II. There was a significant difference (P < 0.05) between group I in comparison to group III. LM examination revealed massive extent of the apoptotic cells in group III when compared to both group I and group II. EM examination of the buffy coat revealed apoptotic changes, mainly in the peripheral blood mononuclear cells (PBMNCs), represented by surface membrane ruffles and blebs with clumped nuclear chromatin and vacuolated cytoplasm. In conclusion, this study may help us to better understand one of the escape mechanisms in cancer larynx. This mechanism is represented by the significant increase in both the serum level of sFas and the morphological apoptotic changes that detected in PBMNCs. Soluble Fas may contribute to the progression of laryngeal cancer. It can be used as an attractive target for anticancer therapy and may be considered as a marker of disease progression and poor prognosis in laryngeal cancer.

scholarly journals EFFECTS OF TRAINING SIDE HOP OVER BARRIER WITH DUMBELL AND HEXAGON WITH DUMBELL ON LEG STRENGTH AND LEG POWER

2018 ◽  
Vol 2 (2) ◽  
pp. 46
Author(s):  
Nur Akbari ◽  
Oce Wiriawan ◽  
Nining Widyah Kusnanik
Keyword(s):  
Control Group ◽  
Percentage Increase ◽  
Design Data ◽  
Group Iii ◽  
Strength Group ◽  
Leg Strength ◽  
Group I ◽  
Significant Difference ◽  
Quasi Experimental ◽  
Group Ii

This study was conducted at 45 students of SMAN 1 Cerme with aged between 15-16 years old. Students were  divided into 3 groups. the type of research used quantitative with quasi-experimental approach. Instruments of this study were test of leg strength and leg power using Leg Dynamometer and  Jump MD. The research design used matching only design. Data was anlyzed using ANOVA. The results of the  research was found that training program side hop over  barrier with dumbell and hexagon with  dumbbell significantly increase at leg strength and leg power (Sig. 0.000 <α = 0.05). Group I, Group II and Group III had significant difference (Sig. 0.000 α = 0.005). Percentage increase in leg strength group 1 of 1,80% and leg  power of 15,49%. Percentage increase in leg strength group II of  1,68% and a power of 14,27% and whereas in the control group increase in leg strength was 1.67% power at 12.32%.It can be concluded that There was an increase in leg strength and leg power in each group after the training was given. In addition, there were differences among the three groups effects seen improved in leg strength and leg power through ANOVA, where the training side hop over barrier with dumbbell and hexagon with dumbell had increased in leg strength and leg   power. But side hop over barrier with dumbbell had more significant increased than hexagon with dumbbell. Key words: Side hop over with barrier dumbell,  hexagon with dumbell, leg strength and leg power.

scholarly journals The effects of astaxanthin on salivary gland damage caused by cisplatin in the rat

2017 ◽  
Vol 5 (4) ◽  
pp. 1410
Author(s):  
Suat Terzi ◽  
Abdulkadir Özgür ◽  
Tolga Mercantepe ◽  
Metin Çeliker ◽  
Levent Tümkaya ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Submandibular Gland ◽  
Cell Density ◽  
Group Iv ◽  
Control Group ◽  
Group V ◽  
Group Iii ◽  
Significant Difference ◽  
The Mean ◽  
And Control

Background: Cisplatin is a potent antineoplastic agent widely used for a variety of malignancies. However, it has many dose-limiting side effects such as neurotoxicity, cytotoxicity and ototoxicity. The aim of our study was to determine the effectiveness of astaxanthin (ASX) as a cytoprotective agent against cisplatin-induced cytotoxicity in the submandibular glands of rats.Methods: Thirty-six adult male Wistar albino rats were divided into six groups as follows: group I: saline control; group II: 75 mg/kg/day ASX; group III: 16 mg/kg cisplatin; group IV: 25 mg/kg/day ASX + cisplatin; group V: 75 mg/kg/day ASX + cisplatin; group VI: olive oil + cisplatin. In all groups, submandibular gland histopathological and histochemical investigations were done using a light microscope. Every rat section was semi-quantitatively scored. Neutrophil infiltration density, myoepithelial cell density in the degeneration area, degenerative granular duct cell density, degenerative seromucous acinus cell density, and changes in the content of the secretory granules of seromucous acini and granular ducts of the parenchyma and stroma were calculated.Results: The results of the analysis of the mean acinus area of the submandibular gland revealed that there was a significant decrease in cisplatin group rats when compared to control rats (p<0.05, p=0.00). However, there was no significant difference between-group IV, V and control group in terms of mean acinus area. (p=0.541, p=0.773). The results of the analysis of the mean ducts area of the submandibular gland also showed that there were significant increased group III compared to control rats (p<0.05, p=0.031). There was no significant difference between-group IV, V and control group in terms of mean ducts area (p>0.05, p=0.921). Similarities were observed in the mean ducts area with the group IV and the group V (p>0.05, p=0.571).Conclusions: These results suggest the possibility that the clinical use of ASX could reduce or prevent damage to the salivary gland of patients receiving cisplatin chemotherapy.

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