scholarly journals Genauigkeit der Dualenergie-Röntgenabsorptiometrie (DXA) zur Ermittlung der Körperzusammensetzung von Schweinen <i>in vivo</i>

2006 ◽  
Vol 49 (5) ◽  
pp. 462-476 ◽  
Author(s):  
A. M. Scholz ◽  
M. Förster
Keyword(s):  
Body Composition ◽  
Body Weight ◽  
Bone Mineral ◽  
The Body ◽  
Whole Body ◽  
Lean Meat ◽  
Group I ◽  
Group Ii ◽  
Weight Groups

Abstract. Title of the paper: Accuracy of dual energy X-ray absorptiometry (DXA) for the determination of the body composition of pigs in vivo New methods for the measurement of the body composition in vivo (or post mortem) like DXA need to be evaluated before routine use in livestock research or performance testing. Two body weight groups of pigs I) 30–50 kg (n=61) and II) 70–90 kg (n=62) were studied in this analysis. The whole bodies of the pigs were analyzed by a GE Lunar DPX-IQ scanner in vivo for the amount and percentage of fat, lean tissue, bone mineral, and the bone mineral density as well. Three days later, pigs were slaughtered and after a 24 h cooling period, the reference parts (shoulder, loin, side, and ham) of the left carcass half were dissected into lean meat, fat, bone, tendons, connective tissue and skin according to the EU reference method. Generally, DXA variables explained a high proportion of variation (R²>0.8; √MSE=70–784 g) in the tissue masses of the reference parts (fat, muscle, bone) in both weight groups. The fat percentage of the reference parts and the DXA whole body results (in vivo) showed a very high relationship with a maximum R²=0.82 (√MSE=1.47%) for group II. Slightly lower was the relationship between the lean meat content (%) of the reference parts and DXA results in vivo (R2=0.72; √MSE=1.75) for group II. The bone percentage was predicted with R²=0.3 (√MSE=0.64), caused by the very different analysis methods. Generally, DXA is a suitable method for growth studies in the above body weight range. In order to predict the percentage of muscle (lean meat) or fat tissue accurately by DXA, pigs should weigh >50 kg, since the soft tissue percentages of group I resulted in R²≤0.38 (√MSE≤2.55).

scholarly journals Comparison between Vinorelbine–Carboplatin and Vinorelbine–Cisplatin in Stage III–IV EGFR Mutations-Negative NSCLC

2021 ◽  
Author(s):  
Laksmi Wulandari ◽  
Gatot Soegiarto ◽  
Anna Febriani ◽  
Farah Fatmawati ◽  
Wirya Sastra Amran
Keyword(s):  
Lung Cancer ◽  
Body Weight ◽  
Evaluation Criteria ◽  
Growth Factor Receptor ◽  
The Body ◽  
Stage Iii ◽  
Egfr Mutations ◽  
Group I ◽  
Significant Difference ◽  
Group Ii

Abstract Introduction There are a substantial number of lung cancer patients with negative mutations in Indonesia. This type of cancer is deemed to be the major contributor of lung cancer patient’s death. However, reseaerch related to therapy using vinorelbine combined with platinum-based compounds is still scarce in Indonesia. The aim of this study was to compare the efficacy and tolerability between vinorelbine and carboplatin with vinorelbin and cisplatin in stage III-IV epidermal growth factor receptor (EGFR) mutations-negative non-small cell lung cancer (NSCLC). Methods The participants were divided into two groups—group I(vinorelbine–carboplatin) and group II (vinorelbine–cisplatin). The participants were assessed based on several measurement criteria. Not only Eq-5D was performed, but the body weight and response evaluation criteria for solid tumors (RECIST) were also examined. The participants received chemotherapy for four cycles (1 cycle = 21 days). Results The quality of life was considered stable in 60% of group I and 60% of group II (p=0.255). In both groups, 46.67% of participants had an increased body weight, while the other 20.00% was stable (p = 1.000). In terms of RECIST evaluation after the second cycle, 80.00% of group I and 86.67% of group II were considered to have a stable disease, with 20% of group I and none of group II had partial response (p = 0.027). However, after the fourth cycle, there were no significant difference between the groups (p = 0.734). Conclusion In EGFR mutation-negative NSCLC patients, the combination of vinorelbine and carboplatin showed comparable outcomes to vinorelbine and cisplatin chemotherapy with no significant differences.

scholarly journals Follow-up of GK rats during prediabetes highlights increased insulin action and fat deposition despite low insulin secretion

2008 ◽  
Vol 294 (1) ◽  
pp. E168-E175 ◽  
Author(s):  
Jamileh Movassat ◽  
Danièle Bailbé ◽  
Cécile Lubrano-Berthelier ◽  
Françoise Picarel-Blanchot ◽  
Eric Bertin ◽  
...  
Keyword(s):  
Body Composition ◽  
Insulin Secretion ◽  
Insulin Sensitivity ◽  
Cell Function ◽  
Cell Mass ◽  
The Body ◽  
Whole Body ◽  
Β Cell ◽  
Gk Rats

The adult Goto-Kakizaki (GK) rat is characterized by impaired glucose-induced insulin secretion in vivo and in vitro, decreased β-cell mass, decreased insulin sensitivity in the liver, and moderate insulin resistance in muscles and adipose tissue. GK rats do not exhibit basal hyperglycemia during the first 3 wk after birth and therefore could be considered prediabetic during this period. Our aim was to identify the initial pathophysiological changes occurring during the prediabetes period in this model of type 2 diabetes (T2DM). To address this, we investigated β-cell function, insulin sensitivity, and body composition in normoglycemic prediabetic GK rats. Our results revealed that the in vivo secretory response of GK β-cells to glucose is markedly reduced and the whole body insulin sensitivity is increased in the prediabetic GK rats in vivo. Moreover, the body composition of suckling GK rats is altered compared with age-matched Wistar rats, with an increase of the number of adipocytes before weaning despite a decreased body weight and lean mass in the GK rats. None of these changes appeared to be due to the postnatal nutritional environment of GK pups as demonstrated by cross-fostering GK pups with nondiabetic Wistar dams. In conclusion, in the GK model of T2DM, β-cell dysfunction associated with increased insulin sensitivity and the alteration of body composition are proximal events that might contribute to the establishment of overt diabetes in adult GK rats.

scholarly journals Investigation of the Protective Effects of Taurine against Alloxan-Induced Diabetic Retinal Changes via Electroretinogram and Retinal Histology with New Zealand White Rabbits

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Samuel Tung-Hsing Chiang ◽  
Shang-Min Yeh ◽  
Yi-Chen Chen ◽  
Shiun-Long Lin ◽  
Jung-Kai Tseng
Keyword(s):  
Body Weight ◽  
Protective Role ◽  
The Body ◽  
Antidiabetic Activity ◽  
Protective Effects ◽  
Group Iii ◽  
Glucose Levels ◽  
Diabetic Retina ◽  
Group I ◽  
Group Ii

The purpose of this study was to investigate the protective role of orally administered taurine against diabetic retinal changes via electroretinogram (ERG) and retinal histology on rabbits. Rabbits were randomly assigned into groups: Group I (vehicle administration only); Group II (diabetes: induced by 100 mg/kg alloxan injection); Group III (diabetes and fed with 200 mg/kg taurine); and Group IV (diabetes and fed with 400 mg/kg taurine). The body weight and blood glucose levels of the rabbits were monitored weekly. The ERG was measured on weeks 5 and 15. Retinal histology was analyzed in the end of the experiment. Results revealed that a taurine supplement significantly ameliorates the alloxan-induced hyperglycemia and protects the retina from electrophysiological changes. Group II showed a significant(P<0.05)change in the mean scotopic b-wave amplitude when compared to that of Group I, whereas the diabetic rabbits treated with taurine (Group III and IV) were analogous to Group I. Histologically, the amount of Bipolar and Müller cells showed no difference(P>0.05)between all groups and when compared with those of Group I. Our study provides solid evidences that taurine possesses an antidiabetic activity, reduced loss of body weight, and less electrophysiological changes of the diabetic retina.

Compensatory growth in immature sheep: I. The effects of weight loss and realimentation on the whole body composition

1975 ◽  
Vol 85 (2) ◽  
pp. 193-204 ◽  
Author(s):  
K. R. Drew ◽  
J. T. Reid
Keyword(s):  
Body Composition ◽  
Body Weight ◽  
Body Fat ◽  
Good Predictor ◽  
Dry Matter ◽  
Body Water ◽  
The Body ◽  
Whole Body ◽  
Body Protein ◽  
Ad Libitum

SUMMARYForty-eight cross-bred wether lambs were used to measure the effects of severe feed restriction and realimentation on the body and carcass composition of immature sheep. Ten of the total number of sheep were used as an initial slaughter group, 12 were continuously fed (six at the ad libitum level of intake and six at 70% ad libitum), 26 were progressively underfed and 18 of them were realimented after a mean loss of about 25% empty body weight (EBW).Shrunk body weight (SBW = weight after an 18-h fast with access to water) was a good predictor of empty body weight (EBW = SBW minus gastro-intestinal contents) and the EBW of continuously growing sheep was a good predictor of body water, protein, fat, energy and ash, but it was not precise after realimentation, particularly in the early stages of refeeding. Restricted continuous supermaintenance feeding did not alter the body composition of the sheep from that of the sheep on the ad libitum intake at any given EBW except slightly to increase the carcass protein content.Although underfeeding to produce an EBW loss of 25% generally produced changes in the chemical body components which were similar to a reversal of normal growth, body fat did not decrease during the first half of the submaintenance feeding and did not increase during the first 2 weeks of realimentation. Under all circumstances percentage body fat was very closely related to percentage body water.Sheep realimented at 26 kg (after losing 25% EBW) contained, at 45 kg EBW, more bodywater and protein and less fat and energy than continuously-fed animals of the same EBW. The treatment effects were greater in the carcass and had little effect on the non-carcass EBW, with th e result that the refed sheep had 1800 g more water × protein in a carcass that weighed 700 g more than one from a normally grown sheep of the same EBW. The regression of calorific value of th e ash-free dry matter on body fat as a percentage of ash-free dry matter gave calorific values of body protein and fat as 5·652 and 9·342 kcal/g of ash-free dry matter, respectively.

Prediction of the body composition of lambs from the composition of their non-carcass components

1995 ◽  
Vol 61 (2) ◽  
pp. 265-268 ◽  
Author(s):  
R. G. Wilkinson ◽  
J. F. D. Greenhalgh
Keyword(s):  
Body Composition ◽  
Body Weight ◽  
Chemical Composition ◽  
Chemical Analysis ◽  
Specific Gravity ◽  
Crude Protein ◽  
Energy Content ◽  
The Body ◽  
Viable Alternative ◽  
Whole Body

AbstractInformation on the chemical composition of Suffolk × Blackface lambs was collected and used to predict empty body (EB) component weights from empty body weight (EBW) and non-carcass (NC) component weights. EBW accounted proportionately for 0·94, 0·89 and 0·95 of the variation in EB crude protein, fat and energy content. A combination of NC component weights accounted proportionately for 0·94, 0·95 and 0·96 of the variation in EB crude protein, fat and energy content. EBW and a combination of NC component weights together accounted proportionately for 0·97, 0·97 and 0·98 of the variation in EB crude protein, fat and energy content. Chemical analysis of NC components is cheaper and easier than whole body analysis and provides a viable alternative to sample joint or specific gravity analysis.

Chemical and elemental analysis of humans in vivo using improved body composition models

1991 ◽  
Vol 261 (2) ◽  
pp. E190-E198 ◽  
Author(s):  
S. B. Heymsfield ◽  
M. Waki ◽  
J. Kehayias ◽  
S. Lichtman ◽  
F. A. Dilmanian ◽  
...  
Keyword(s):  
Body Composition ◽  
Body Weight ◽  
Actual Body ◽  
Elemental Analysis ◽  
Human Subjects ◽  
National Laboratory ◽  
Brookhaven National Laboratory ◽  
Whole Body ◽  
Highly Correlated

Six chemical compartments [water, protein, mineral (osseus and cellular), glycogen, and fat] consisting of 11 elements (N, C, Ca, Na, Cl, K, H, P, O, S, and Mg) comprise greater than or equal to 99% of body weight in living humans. The combination of three neutron-activation systems, whole body 40K counting, and 3H2O dilution at Brookhaven National Laboratory now potentially makes it possible to quantify greater than or equal to 96% of the chemical and elemental determinants of body weight in vivo. The aims of the present study were 1) to develop 6- and 11-compartment chemical and elemental models, respectively, and 2) to evaluate these models in a group of 20 healthy adults. Results demonstrated that body weight estimated from either chemical or elemental components was highly correlated with (both r = 0.97, P less than 0.001) and on average differed by less than 4% from actual body weight. The compartmental results obtained using the chemical model were also evaluated by comparing calculated and actual body density (Db) estimated by underwater weighing. Calculated Db [1.041 +/- 0.017 (SD) g/ml] agreed closely and was highly correlated with actual Db (1.039 +/- 0.018 g/ml; r = 0.82; P less than 0.001). Hence a near-complete chemical and elemental analysis of living human subjects is now possible and, with potential future refinements, represents an important opportunity to quantify the effects of gender, aging, and ethnic status on body composition.

The body composition of growing sheep during milk feeding, and the effect on composition of weaning at various body weights

1976 ◽  
Vol 86 (3) ◽  
pp. 483-493 ◽  
Author(s):  
T. W. Searle ◽  
D. A. Griffiths
Keyword(s):  
Body Composition ◽  
Body Weight ◽  
Tritiated Water ◽  
Body Weight Loss ◽  
The Body ◽  
Whole Body ◽  
Protein Energy ◽  
Body Weights ◽  
Similar Body ◽  
Milk Feeding

SummaryThirty-four (13♂, 21♀) entire cross-bred lambs were suckled on reconstituted, spray-dried cows' milk from 2 days of age for varying periods of time up to 18 weeks before being weaned on to solid food or slaughtered to determine chemical composition. The body composition of each sheep (water, fat, protein, energy) was also estimated from the tritiated water (TOH) space at 3-weekly intervals during milk feeding, at intervals of 5–8 weeks subsequently and at slaughter. Comparison between. TOH estimates and whole body analysis confirmed the accuracy of the previously-derived prediction equations.The relationship between each of the various body components and body weight for individual sheep during milk feeding was described by a ‘bent’ (non-rectangular) hyperbola. There were no substantial differences between animals in either the position or slope of the lower asymptote nor in the slope of the upper asymptote. There were, however, substantial differences in the point of intersection of the two asymptotes both within and between sexes. The mean intersection points for males and females were 17·7 and 14·4 kg body weight respectively.Sheep weaned at body weights of 11–16 kg subsequently followed the previously defined pattern of growth. Weaning at higher body weights (21–34 kg, body fat not less than 5·5 kg) resulted initially in both fat and/or body weight loss. In the final fattening phase of growth early- and late-weaned sheep of the same sex had similar body composition but females were fatter than males.

scholarly journals Comparison of a GE Lunar DPX-IQ and a Norland XR-26 dual energy X-ray absorptiometry scanner for body composition measurements in pigs – <i>in vivo</i>

2010 ◽  
Vol 53 (2) ◽  
pp. 162-175 ◽  
Author(s):  
D. Lösel ◽  
P. Kremer ◽  
E. Albrecht ◽  
A. M. Scholz
Keyword(s):  
Body Composition ◽  
Bone Mineral ◽  
Performance Testing ◽  
Dual Energy ◽  
The Body ◽  
Fat Percentage ◽  
Mineral Density ◽  
X Ray ◽  
And Performance

Abstract. In the context of future growth and performance testing, this study compares corresponding body composition results measured by two dual energy X-ray absorptiometry systems. To test the capability of each device to detect differences among experimental groups widely varying in body composition, 77 pigs from 6 purebred/crossbred groups were used for the experiment. Each pig was scanned consecutively on a Norland XR-26 and on a GE Lunar DPX-IQ. Coefficients of determination were: R²=0.92 for bone mineral content (BMC), R²=0.90 for bone mineral density (BMD), R²=0.94 for lean mass (LEAN), R²=0.92 for fat mass (FAT), R²=0.88 for lean percentage (%LEAN) and fat percentage (%FAT). However, Norland yielded larger values for %FAT and smaller values for %LEAN, BMC, and BMD than Lunar (P<0.001) with the extent of deviation depending on the specific trait and on the breeding group. The deviation in BMC was greater than the deviation in BMD, suggesting different bone detecting algorithms. Both systems revealed similar differences among the breeding groups, and ranked them in the same order based on numerical values. Differences in calibration, bone detection, and software algorithms, however, require a prior crosscalibration to make the body composition data from both systems directly comparable. Finally, they can be used across research centres for the determination of relative and absolute body composition differences among animal groups and individuals.

scholarly journals Assessment of Effect of Exercise on Body Composition in Obese and Overweight

2022 ◽  
Vol 8 (1) ◽  
pp. 1-6
Author(s):  
Reshma Shireesha ◽  
Obulesu Obulesu
Keyword(s):  
Body Composition ◽  
Body Fat ◽  
Health Benefit ◽  
The Body ◽  
Control Group ◽  
Fat Percentage ◽  
Group I ◽  
Significant Difference ◽  
The Mean ◽  
Group Ii

Background: Aim: To assess the effect of exercise on body composition in obese and overweight. Methods: A total of seventy- two overweight subjects of either gender were enrolled for the study. Two groups were prepared. One group was experimental group (n=36) and the second group was control group (n=36). Parameter such as age, height and weight was recorded. On the basis of variables body mass Index and body fat percentage of every subject was determined. The experiment group were put on aerobic exercises spread over duration of four weeks. Results: The mean height in group I was 163.7 cm and 165.4 cm in group II. Weight was 65.2 kg and 63.5 kgs in group II, BMI (Kg/m2) was 29.4 and 29.1, body fat was 29.3% and 29.6% in group I and II respectively. A significant difference was observed (P< 0.05). The mean pre- test BMI was 29.6 and 38.5 and post- test value was 26.4 and 38.9 in group I and II respectively. A significant difference was observed (P< 0.05). Conclusions: Regular physical activity appears to confer a health benefit to the people. There was a positive relationship between aerobic exercises and overweight women in order to reduce the value of fat in the body.

scholarly journals Body composition of piglets exhibiting different growth rates

2012 ◽  
Vol 55 (4) ◽  
pp. 356-363 ◽  
Author(s):  
A. D. Mitchell ◽  
T. G. Ramsay ◽  
T. J. Caperna ◽  
A. M. Scholz
Keyword(s):  
Body Composition ◽  
Body Weight ◽  
Bone Mineral Content ◽  
Bone Mineral ◽  
Mineral Content ◽  
Growing Pigs ◽  
The Body ◽  
Body Composition Measurement ◽  
Total Body ◽  
Highly Correlated

Abstract. The growth and composition of the neonatal pig is of interest because of potential impact on subsequent growth and finally, composition at market weight. The purpose of this study was to compare at weaning the growth and body composition of the largest and smallest pigs from each of 38 litters. At weaning (27±1.7 d) the largest (9.3±1.1 kg) and smallest (6.2±1.5 kg) pigs were selected for body composition measurement by dual energy X-ray absorptiometry (DXA). The body composition of the largest pigs consisted of 38 % more fat, 32 % more lean, and 29 % more bone mineral content (P<0.001). However, when expressed as a percentage of body weight, there was no difference in the fat, lean or bone mineral content content of the two groups of pigs (P>0.05). A second study consisted of 12 pairs of pigs from 8 litters that were selected on the basis of having the same birth weight, but one pig out gaining the other by at least 50 g/day. At 21 days of age the selected pigs were scanned by DXA. For both groups combined, the correlation (r) between body weight and lean mass was 0.99, between body weight and fat mass it was 0.87, and between body weight at birth and body weight at weaning it was 0.56. The results of these studies revealed that, at weaning, the fastest and slowest growing pigs had similar proportions of fat, lean and bone mineral and, consistent with previous results, the rates of both fat and lean deposition were highly correlated (P<0.001) with total body growth rate.

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