scholarly journals SUMMARY: SITUATION OF USING DRUGS FOR GOUT TREATMENT OF INPATIENTS

2021 ◽  
Vol 62 (2) ◽  
Author(s):  
Đặng Quang Phúc ◽  
Đỗ Văn Mãi ◽  
Hoàng Đức Thái ◽  
Bùi Đặng Minh Trí
Keyword(s):  
General Hospital ◽  
Drug Combination ◽  
Medical Records ◽  
Clinical Symptoms ◽  
Combination Regimen ◽  
Drug Side Effects ◽  
Cross Sectional ◽  
Inpatient Group ◽  
Digestive Disorders ◽  
Can Tho City

  Objective: To describe the current situation of using drugs to treat gout on inpatients at Can Tho City General Hospital. Subjects and methods: Retrospective, cross-sectional, descriptive, non-intervention study based on inpatient medical records for gout treatment at Can Tho City General Hospital with admission time from June 2019 to December 2019. Results: The majority of patients were prescribed colchicine, accounting for 91.35%, followed by oral and injected meloxicam, with 55.77.0% and 29.81% respectively. Inpatients using a single regimen mainly used paracetamol (accounting for 36.11%) and colchicine (accounting for 22.22%). The most commonly used 2-drug inpatient regimen included: colchicin + oral paracetamol (30.43%), oral meloxicam + oral paracatamol (19.57%). The 3-drug combination regimen on the inpatient group includes: colchicin + injected meloxicam + oral paracetamol (accounting for 61.11%). The four-drug combination regimen was colchicin + injected meloxicam + oral methylprednisolon + infused paracetamol. The majority of inpatients had the regimen changed due to improved clinical symptoms (accounting for 64.13%). Approximately 25.54% of patients need changes due to more severe clinical symptoms. Only 6 medical records showed adverse events during the treatment process, accounting for 5.77%. In which, digestive disorders accounted for the highest percentage with 50.0%. Conclusion: Gout inpatients were mainly indicated for the use of colchicin and meloxicam. The main regimens used in monotherapy were paracetamol and colchicin, the multitherapy regimen mainly used colchicin, meloxicam and paracetamol. Drug side effects were low at 5.77%.

scholarly journals Pattern and Frequency of Skin Malignancies at Laboratory of Pathology Anatomy Dr. Kariadi General Hospital in 2008-2009

Sains Medika ◽  
2015 ◽  
Vol 6 (1) ◽  
pp. 21
Author(s):  
Susilorini Susilorini ◽  
Udadi Sadhana ◽  
Indra Widjaya
Keyword(s):  
Squamous Cell Carcinoma ◽  
Skin Cancer ◽  
Skin Lesion ◽  
Cell Carcinoma ◽  
General Hospital ◽  
Squamous Cell ◽  
Medical Records ◽  
Secondary Data ◽  
Cross Sectional ◽  
Neoplastic Lesion

Introduction: A periodical database is important including for skin cancer. Periodical registration is needed to acknowledge changes in pattern and frequencies of skin lesion. Objective: The purpose of this study was to describe the pattern and the frequency of skin lesion in RSUD Kariadi.Method: A cross-sectional study was conducted through analysis of the medical records of patients diagnosed skin lesion in the pathology labolatory of RSUD Kariadi between 2008 and 2009. The variables were secondary data including age, gender, specimen area, dan histopathology diagnosis. Data was choosen by consecutive sampling from 381 medical records of skin tissues examined at laboratorium of pathology anatomy of Dr. Kariadi general hospital during 2008-2009.Result: 381 cases were recorded comprising of 246 (65%) neoplastic and 135 (35%) non neoplastic lesion. 120 patients presented with skin cancer, and 126 with benign skin lesion. Most malignancy was observed among female patients (62.5%) on age catagory of 15-39 (65%). The most common lesion was basal cell carcinoma (48.3%) followed by squamous cell carcinoma (33.3%), malignant melanoma (10%), skin appendix carcinoma (2.5%), other malignancies (4.9%).Conclusion: the most common malignancies in Dr. Kariadi general hospital before 2008 was similar to data from 13 laboratory of pathology anatomy in Indonesia, which is squamous cell carcinoma.

scholarly journals Response and Side Effects from Rheumatoid Arthritis Therapy at Dr. Soetomo General Hospital Surabaya 2017

2022 ◽  
Vol 13 (1) ◽  
pp. 9
Author(s):  
Ayu Imamatun Nisa ◽  
Awalia Awalia ◽  
Jusak Nugraha
Keyword(s):  
Rheumatoid Arthritis ◽  
Side Effects ◽  
General Hospital ◽  
Clinical Symptoms ◽  
Laboratory Data ◽  
Kidney Injury ◽  
Cross Sectional ◽  
Reactive Protein ◽  
Cross Sectional Design ◽  
The Given

Introduction: Rheumatoid arthritis (RA) is an autoimmune disease which mainly attacks synovial membrane and causes systemic manifestation. During treatment, controlling disease activity is needed to prevent further complication. On the other hand, medications used in the treatment of RA may bring various side effects. It is important to evaluate side effects from the given therapy.Methods: This study aimed to evaluate response and side effects of therapy in RA patients. The samples were collected from 59 RA patients at Rheumatology Division of Outpatient Clinic in Department of Internal Medicine Dr. Soetomo General Hospital Surabaya in 2017. This study method was descriptive observational with cross sectional design using medical records.Results: Pain was reduced in 83.1% patients, Erythrocyte Sedimentation Rate (ESR) increased in 61.4% patients, and C-Reactive Protein (CRP) decreased in 50% patients. Based on the statistic analysis, ESR decreased significantly (p = 0.012) while CRP decreased not significantly (p = 0.415). The side effects were observed from clinical and laboratory data. Based on clinical symptoms, there were alopecia in 1.7% patient, dyspepsia in 78% patients, infection in 27.1% patients, and other symptoms including itchy skin, neuropathy, hyperuricemia, hyperkalemia and Acute Kidney Injury (AKI). Meanwhile, abnormalities in laboratory data include increased aspartate transaminase (AST) in 3.8% patients, increased alanine transaminase (ALT) in 26.1% patients, increased Blood Urea Nitrogen (BUN) in 7.9% patients, increased creatinine serum in 7.9% patients, decreased hemoglobin in 15.5% patients, and decreased leukocytes in 3.4% patients.Conclusion: Most patients had a good therapeutic response based on decreased pain, while ESR had a significant decrease and CRP did not have significant decrease. Side effects discovered in patients were various

Efficacy and safety of sofosbuvir plus daclatasvir with or without ribavirin in treatment of Egyptian patients infected with chronic HCV (Single Centre Study)

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Mohammed Shaker ◽  
Heba Abdella ◽  
Zeinab hefny
Keyword(s):  
General Hospital ◽  
Cross Sectional Study ◽  
World Health ◽  
Combination Regimen ◽  
Efficacy And Safety ◽  
Cross Sectional ◽  
Group I ◽  
Egyptian Patients ◽  
Group Ii ◽  
Chronic Hcv

Abstract Background and aim As indicated by the World Health Organization (WHO), Egypt is positioned as the country with the world’s highest prevalence of Hepatitis C virus (HCV). The current study was designed to describe the efficacy and safety of Sofosbuvir plus Daclatasvir with or without Ribavirin in treatment of chronic HCV in a cohort of Egyptian patients who were referred to the viral hepatitis unit in El -Fayoum general hospital. Methods This is a prospective descriptive cross sectional study that describes the effect of 12 weeks of daily Sofosbuvir (SOF) 400 mg plus Daclatasvir (DCV) 60 mg with or without ribavirin (RBV) with dose adjustment if indicated. It included 200 patients that fulfilled the inclusion and exclusion criteria and treated in El -Fayoum general hospital, El-Fayoum, Egypt. Results In the current study, concerning viral response, SVR12 rate was achieved by 92.5% in the overall patients (185/200); by 98% (98/100) in group I, and by 87% (87/100) in group II. Concerning safety and tolerability, The main adverse effects recorded during and after 12 weeks of treatments were fatigue (46%), (66%); headache (24%), (40%); gastrointestinal upset (15%), (43%); and nausea (10%), (15%) in group 1 and group 2, respectively. Only one female patient in group II developed HCC. All patients completed treatment till the end of course. Conclusion The current study suggested that treatment of SOF plus DCV with/without RBV for chronic HCV patients in Egypt was generally safe, well tolerated, and of high efficacy, reflecting the antiviral potency and high resistance barrier of the combination regimen.

scholarly journals Characteristics of Mediastinal Tumors in Dr. Hasan Sadikin General Hospital, Periods of 2011-2016

2018 ◽  
Vol 2 (2) ◽  
Author(s):  
Octavianus Giovani ◽  
Hasrayati Agustina ◽  
Teguh M Djajakusumah
Keyword(s):  
Epithelial Cell ◽  
Medical Records ◽  
Mediastinal Tumor ◽  
Clinical Symptoms ◽  
Cell Tumor ◽  
Cross Sectional ◽  
Mediastinal Tumors ◽  
Mediastinal Disease ◽  
Chief Complaints ◽  
Histopathologic Findings

Mediastinal tumors are considered to be mediastinal disease with various clinical and histopathologic presentations. In Indonesia, literatures concerning mediastinal tumors are still few. This study aims to obtain the characteristic of mediastinal tumors in Dr.Hasan Sadikin Hospital. A cross-sectional retrospective study was conducted using medical records from 2011 to 2016. All medical records with clinical diagnosis of mediastinal tumors are included, and cases with metastatic tumors from distant sites to the mediastinum, and/or incorrect histopathologic findings are excluded. We obtain data of age, gender, clinical symptoms, histopathologic finding, and staging, with total samples collected of 72. We find out that patients with mediastinal tumors are mainly over 40 years old (62.5%), especially in the 6th decade of life (23.6%), and were mostly of males (73.6%). Patients mainly had chief complaints of dyspnea (38.7%), followed by cough and typical myasthenia gravis symptoms. The most common type of mediastinal tumor is epithelial cell tumor (68.4%), and the most common stage is Masaoka-Koga stage III (37.5%). This study concludes that mediastinal tumor mainly occurs in males aged 40 years old and above, with epithelial cell tumor as the most common histopathologic findings.Keywords : characteristics; mediastinal tumor; mediastinum

scholarly journals Impact of expanding the clinical pharmacy service in the emergency department at Hamad General Hospital, a tertiary hospital in Qatar: A cross-sectional audit

2021 ◽  
Vol 2021 (2) ◽  
Author(s):  
Rawan Salameh ◽  
Asma Ezzeldin ◽  
Ashraf El-Malik ◽  
Ibtisam Musameh ◽  
Sara Nazzal ◽  
...  
Keyword(s):  
Emergency Department ◽  
High Risk ◽  
General Hospital ◽  
Medical Records ◽  
Tertiary Hospital ◽  
Clinical Pharmacy Service ◽  
Cross Sectional ◽  
Retrospective Audit ◽  
High Risk Populations ◽  
The Impact

Background: The emergency department (ED) is a complex environment presenting unique challenges for high-risk populations such as critically ill patients who often require the use of high-risk medications. One study suggests that clinical pharmacists (CPs) may improve the fulfillment of safety goals for the ED patient as per the Joint International Commission. Some published reports have asserted that ED-based CPs would have the potential to increase patient safety. In our hospital, the number of CPs covering the ED increased from 2 to 9 starting from November 2019. Methods: This is a retrospective audit covering the period from January 1st 2019 till October 25th 2020 at Hamad General Hospital (HGH) in Doha, Qatar, to determine the impact of increasing the number of CPs covering the ED on the number of identified, solved, and documented drug related problems (DRPs) on the electronic medical records of ED patients. The interventions retrieved from pharmacy reports were analyzed and evaluated in terms of numbers by classification and percentages by the investigators. Results: A total number of 8,946 interventions covering 6,284 patients were carried out in 2020 compared with 1,515 interventions covering 1,001 patients in 2019 which represents a 6-fold increment by increasing the CPs from 2 to 9. Even the detection of adverse drug reactions increased by 1.5 times with only 38 documented in 2019 compared to 64 in 2020. Classifications and quantities of interventions were also analyzed in detail. Conclusion: This audit demonstrates that pharmaceutical intervention can positively contribute to the identification and resolution of DRPs. The benefit of CP involvement in patient care was observed based on the number of interventions that occurred. Studies are needed to assess the impact of those interventions on patients’ outcomes and cost effectiveness.

scholarly journals SITUATION OF DRUGS FOR TREATMENT INTESTINAL INFECTION

2021 ◽  
Vol 62 (4) ◽  
Author(s):  
Lam Hoang Khanh ◽  
Nguyen Huu Phuc ◽  
Bui Tung Hiep ◽  
Bui Dang Minh Tri
Keyword(s):  
Medical Records ◽  
Pediatric Patients ◽  
Antibiotic Regimen ◽  
Intestinal Infection ◽  
Beta Lactam ◽  
Cross Sectional ◽  
Children's Hospital ◽  
Frequency Of Use ◽  
Children’S Hospital ◽  
Can Tho City

Objective: To survey the use of drugs to treat intestinal infection at Can Tho Children’s Hospital. Objects and methods: Cross-sectional retrospective descriptive study on 400 medical records of pediatric patients diagnosed with intestinal infection in Can Tho City Children’s Hospital in 2019. Result: There were 353 pediatric patients using rehydration and electrolytes measeurement, ORS with the highest frequency was 38.66%. The antibiotic with the highest frequency of use was the beta-lactam 3rd group. In which, Cefotaxim had the most use frequency. Single regimen of cefotaxim used the most with a frequency of 70.06%. Meanwhile, the antibiotic regimen cefotaxime combined with tobramycin was the highest in the combined regimen with 57.14%. Up to 70 cases changed the regimen due to ineffective results and 22 cases changed the regimen due to its effectiveness, reducing the amount of antibiotics. The first regimen with the highest frequency of change was the cefotaxim regimen with 33 cases. The 2nd regimens changed with the highest frequency were cefotaxim regimen and regimen of cefotaxim combined with tobramycin with 5 cases. The third change of regimen was mostly from combination antibiotic regimen to single regimen. Conclusion: Rehydration and electrolyte measures were mainly ORS. Antibiotics used mainly in the beta-lactam 3rd group, Cefotaxim had the highest frequency of use. Cefotaxim was used the most frequency in a single regimen. The antibiotic combined regimen between cefotaxime and tobramycin was the highest use in all combined regimens. Changing treatment regimen was mainly due to the ineffective effect.

scholarly journals THE TREATMENT EFFECT OF HYPERTENSION DRUGS OF PATIENTS WITH RENAL FAILURE STAGE IV

2021 ◽  
Vol 62 (2) ◽  
Author(s):  
Phan Hùng Duy Hậu ◽  
Bùi Đặng Minh Trí ◽  
Nguyễn Hữu Bền
Keyword(s):  
Blood Pressure ◽  
Renal Failure ◽  
General Hospital ◽  
Medical Records ◽  
Stage Iv ◽  
Cardiovascular Complications ◽  
Ho Chi Minh City ◽  
Cross Sectional ◽  
Grade 3

Objectives: To evaluate the treatment effects of hypertension drugs in patients with stage IV renal failure at An Sinh General Hospital. Objects and methods: study of retrospective, cross-sectional description of 153 medical records of patients diagnosed with hypertension with stage IV chronic renal failure who were treated in the Department of Endocrinology - Dialysis of An Sinh General Hospital, Ho Chi Minh City, from June 1st, 2019 to May 31st, 2020. Results: After 6 months of follow-up of patients with hypertension at grade 2 and 3, there were only 11 patients. Normal/normal high blood pressure (BP) (<140/90mmHg) was achieved at 53.49%, however, target blood pressure (TBP) (<130/80 mmHg) was only reached in 33.99% of patients. Changes in renal function indexes after hemodialysis and after treatment had no significant                    difference compared with before treatment with drugs of hypertension. The rate        of patients with new cardiovascular complications after 6 months of follow-up had a small rate of 3.27%. Conclusion: The ratio of patients with hypertension at grade 2 and grade 3 was clearly reduced. The TBP rate was in the average level. The rate of patients with new cardiovascular complications after 6 months of follow-up was low.

scholarly journals THE CURRENT SITUATION OF USING DRUGS FOR HYPERTENSION OUTPATIENTS

2021 ◽  
Vol 62 (2) ◽  
Author(s):  
Bùi Tùng Hiệp ◽  
Nguyễn Thị Xuân Hoàng ◽  
Đỗ Văn Mãi ◽  
Nguyễn Đức Lộc
Keyword(s):  
Combination Therapy ◽  
Drug Interactions ◽  
Calcium Channel ◽  
General Hospital ◽  
Calcium Channel Blockers ◽  
Current Situation ◽  
Combination Regimen ◽  
Channel Blockers ◽  
Cross Sectional ◽  
Calcium Blockers

Objectives: To assess the current situation of using hypertension drugs for outpatients at the examination department of Hau Nghia Regional General Hospital - Long An. Objects and methods: Study of Cross-sectional description, retrospection, non-intervention on 180 patients who came to examine and treat hypertension at the examination Department, stored on the software of the Hau Nghia Regional General Hospital - Long An. Results: Among the drug groups used to treat hypertension, the group of drugs used the most was calcium channel blockers (58.25%), the lowest was diuretics with 3.88%. The regimens used for patients, the number of regimens using one drug accounted for the largest proportion, accounting for 86.67%. The regimen using 2 drugs accounted for 12.22% and the lowest was the combination regimen of 3 drugs with only 2 patients, accounting for 1.11%. In monotherapy was preferred by the doctor over combination therapy, in which Amlodipine was the most prescribed drug. The number of times of drug use per day of some drugs did not comply with recommendations and drug interactions accounted for a high proportion. Conclusion: The treatment regimen of hypertension was mainly monotherapy with calcium blockers, the most common being Amlodipine. However, the number of drugs used per day of some drugs did not comply with recommendations and drug interactions accounted for a high proportion.

scholarly journals The characteristics and patterns of maxillofacial fractures at Mangusada general hospital, Badung-Bali

2019 ◽  
Vol 7 (6) ◽  
pp. 2318
Author(s):  
Agus Bhayu W. Wiwekananda ◽  
I Wayan Arimbawa ◽  
Ratna Rayeni Natasha Roosseno
Keyword(s):  
General Hospital ◽  
Medical Records ◽  
Traffic Accidents ◽  
Causes Of Death ◽  
Age Groups ◽  
Maxillofacial Trauma ◽  
Age Group ◽  
Cross Sectional ◽  
Maxillofacial Fractures ◽  
Gender Based

Background: Trauma is one of the leading causes of death among people under 40 years of age and approximately 10 percent of the cases have been maxillofacial trauma. There was limited number of studies on maxillofacial fractures in Indonesia. Thus, this research attempted to investigate the characteristics and patterns of maxillofacial fractures at Mangusada General Hospital in Badung-Bali.Methods: This research was a cross-sectional descriptive study which conducted at Mangusada General Hospital in the period of 1 January 2016 - 31 December 2017. The 127 samples selected using non-probability sampling. The inclusive criteria involved all maxillofacial trauma cases and the exclusive criteria focused on maxillofacial fractures that received intervention or with incomplete medical records. Each data was collected from the medical records and then analysed descriptively.Results: From 127 samples, male dominated the sample on the gender-based criteria (70.1%) and the highest frequency of all age groups is 21-30 years old on the age group based criteria (23.6%). Maxillary fractures are the most occurring maxillofacial cases, which took up 33.6%. The main cause of the cases is traffic accidents (89.0%).Conclusions: Maxillary fractures are the highest maxillofacial cases at Mangusada General Hospital on 1 January 2016 - 31 December 2016 period of time. The productive male age groups are the most affected groups due to traffic accidents.

scholarly journals CURRENT SITUATION OF MEDICINES USED IN THE TREATMENT OF GATROENTERITIS

2021 ◽  
Vol 62 (1) ◽  
Author(s):  
Đặng Minh Trí Bùi ◽  
Văn Mãi Đỗ ◽  
Thị Như Huỳnh Nguyễn ◽  
Thu Hằng Phạm
Keyword(s):  
Side Effects ◽  
Drug Treatment ◽  
General Hospital ◽  
Outpatient Treatment ◽  
Medical Records ◽  
Current Situation ◽  
High Rate ◽  
Mucosal Protection ◽  
Cross Sectional ◽  
Antiemetic Drugs

Objectives: To investigate the current situation of using drugs to treat gastroenteritis of outpatients at the gastrointestinal department of Vinh Long General Hospital. Subjects and methods: Study of retrospective cross- sectional description on 310 medical records of patients over 18 years old diagnosed with gastroenteritis, outpatient treatment at the internal department, Vinh Long General Hospital from November 2019 to July 2020. Results: Patients using PPI drugs in gastroenteritis accounted for 95.16%, of which Esomeprazole was used the most 38.39%, rabeprazole accounted for 31.94%, lansoprazole accounted for 11.94%, pantoprazole 3.87%. Most of the patients were used in combination with supportive drug treatment. The group of antiemetic drugs, reduce flatulence used with a high rate of 59.68%, the group of mucosal protection drugs accounted for 54.84%. The most common side effects were mild, with 9.35%. Conclusion: Patients using PPI drugs in gastroenteritis accounted for 95.16%, rarely encounter drug interactions and side effects.

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