scholarly journals BEDA LUARAN FUNGSI SENSORIMOTOR PASIEN DENGAN DAN TANPA FATIGUE PASCASTROKE ISKEMIK

Author(s):  
Maria Putri Utami ◽  
Hexanto Muhartomo ◽  
Maria Immaculata Widisastuti

  THE DIFFERENCE OF SENSORIMOTOR FUNCTION OUTCOME IN PATIENTS WITH AND WITHOUT POST ISCHEMIC STROKE FATIGUEABSTRACTIntroduction: Post-stroke fatigue is a burden in improving neurological deficits, rehabilitation, quality of life and capacity at work. Thus, the consequences of post-stroke fatigue should be dealt seriously, considering this is a problem for the patients and difficult to deal with.Aims: To obtain the difference between sensorimotor outcome after ischemic stroke in patients with and without fatigue.Methods: Cohort prospective study of first ischemic stroke patients, conducted at Dr. Kariadi Hospital and Dr. Adhyatma Tugurejo Hospital, Semarang in May-July 2018. Fatigue was determined two weeks post stroke using FACIT-F questionnaire. Sensorimotor outcome was evaluated with Fugl-Meyer Assessment (FMA) two weeks post-stroke and two weeks after the first examination.Results: Among 44 patients with first ischemic stroke, 31.8% patients experienced fatigue and 68.2% patients did not experience it. There was significant sensorimotor outcome difference between patients with fatigue and without fatigue, and also significant variance of sensorimotor outcome difference between those groups.Discussions: Sensorimotor outcome was different between patients with and without post-stroke fatigue. Patients who experienced fatigue had poorer sensorimotor outcome (lower FMA score). They tended to be pessimistic about exercise function and avoided physical activity. Post-stroke fatigue inhibited patient participation in rehabilitation programs and was associated with poor improvement in neurological function.Keywords: FACIT-F, fatigue, Fugl-Meyer Assessment, ischemic stroke, sensorimotor outcomeABSTRAKPendahuluan: Keadaan lelah atau fatigue pascastroke akan menghambat perbaikan defisit neurologis, rehabilitasi, kualitas hidup, dan kapasitas dalam bekerja. Oleh karena itu, konsekuensi fatigue pascastroke harus ditangani secara serius, mengingat hal ini menjadi masalah bagi pasien dan sulit untuk ditangani.Tujuan: Didapatkan perbedaan luaran fungsi sensorimotor pascastroke iskemik pada pasien dengan fatigue dan tanpa fatigue.Metode: Studi kohort prospektif pada pasien stroke iskemik pertama yang dirawat di RSUP Dr. Kariadi dan RSUD Dr. Adhyatma Tugurejo, Semarang pada bulan Mei-Juli 2018. Status fatigue ditentukan 2 minggu pascastroke dengan kuesioner FACIT-F. Luaran fungsi sensorimotor dievaluasi dengan Fugl-Meyer Assessment (FMA) 2 minggu pascastroke dan 2 minggu setelah pemeriksaan pertama.Hasil: Diantara 44 pasien stroke iskemik pertama kali, 31,8% pasien mengalami fatigue dan 68,2% tidak mengalaminya. Adanya perbedaan bermakna luaran fungsi sensorimotor antara pasien dengan fatigue dan tanpa fatigue, juga didapatkan perbedaan bermakna perubahan luaran fungsi sensorimotor antara kedua kelompok tersebut.Diskusi: Luaran fungsi sensorimotor berbeda antara pasien dengan dan tanpa fatigue pascastroke iskemik. Pasien yang mengalami fatigue memiliki luaran fungsi sensorimotor lebih buruk (skor FMA lebih rendah). Pasien dengan fatigue cenderung pesimis akan fungsi olahraga dan menghindari aktivitas fisik. Fatigue pascastroke menghambat partisipasi pasien dalam program rehabilitasi serta berkaitan dengan buruknya perbaikan fungsi neurologis.Kata kunci: FACIT-F, fatigue, Fugl-Meyer Assessment, luaran fungsi sensorimotor, stroke iskemik  

2017 ◽  
Vol 4 (2) ◽  
pp. 133
Author(s):  
Bevi Dewi Citra ◽  
Hermes C. Sitompul ◽  
Tuti Restuastuti

Neurological deficits on stroke patients can caused immobility. Decubitus ulcer is one of immobilty’s complication.Two hours repositioning is one of medical rehabilitation programs in decubitus prevention. The aim of this study is todescribe effectiveness of two hours repositioning to prevent decubitus ulcer, especially on post-stroke patients. Thisstudy was a preventive intervention study with cross-sectional approach. Sample consists of 32 patients. Group Iconsists of 16 patients with repositioning intervention. On the otherhand, group II consists of 16 patients withoutrepositioning intervention. Then, this two groups were compared and were looked for the effectiveness. from thisstudy, we knew that prevalence of decubitus ulcer on post-stroke patients are 19.4% with the effectiveness of two hoursrepositioning is 87.5%. There was significant difference between these two groups to prevent decubitus. it occurred ongeriatric patients with percentage of 75%. Its Proportion for female: male are 2:1. It is commonly occurred on firstweek hospitalization, especially grade 2 (33.3%). It is mostly located on sacrum (100%).


Author(s):  
Natalie E. Parks ◽  
Gail A. Eskes ◽  
Gordon J. Gubitz ◽  
Yvette Reidy ◽  
Christine Christian ◽  
...  

Background:Fatigue affects 33-77% of stroke survivors. There is no consensus concerning risk factors for fatigue post-stroke, perhaps reflecting the multifaceted nature of fatigue. We characterized post-stroke fatigue using the Fatigue Impact Scale (FIS), a validated questionnaire capturing physical, cognitive, and psychosocial aspects of fatigue.Methods:The Stroke Outcomes Study (SOS) prospectively enrolled ischemic stroke patients from 2001-2002. Measures collected included basic demographics, pre-morbid function (Oxford Handicap Scale, OHS), stroke severity (Stroke Severity Scale, SSS), stroke subtype (Oxfordshire Community Stroke Project Classification, OCSP), and discharge function (OHS; Barthel Index, BI). An interview was performed at 12 months evaluating function (BI; Modified Rankin Score, mRS), quality of life (Reintegration into Normal living Scale, RNL), depression (Geriatric Depression Scale, GDS), and fatigue (FIS).Results:We enrolled 522 ischemic stroke patients and 228 (57.6%) survivors completed one-year follow-up. In total, 36.8% endorsed fatigue (59.5% rated one of worst post-stroke symptoms). Linear regression demonstrated younger age was associated with increased fatigue frequency (β=-0.20;p=0.01), duration (β=-0.22;p<0.01), and disability (β=-0.24;p<0.01). Younger patients were more likely to describe fatigue as one of the worst symptoms post-stroke (β=-0.24;p=0.001). Younger patients experienced greater impact on cognitive (β=-0.27;p<0.05) and psychosocial (β=-0.27;p<0.05) function due to fatigue. Fatigue was correlated with depressive symptoms and diminished quality of life. Fatigue occurred without depression as 49.0% of respondents with fatigue as one of their worst symptoms did not have an elevated GDS.Conclusions:Age was the only consistent predictor of fatigue severity at one year. Younger participants experienced increased cognitive and psychosocial fatigue.


2020 ◽  
Vol 8 (2) ◽  
pp. 1-6
Author(s):  
Darma Ericson Saragih ◽  
Azizah Nasution ◽  
Khairunnisa K

Objective: aims to evaluate the COI INA-CBG BPJS patients hospitalized for ischemic stroke BPJS (n = 33) at USU Medan Hospital in February 2019-August 2019 period. Design: this study was conducted used a prospective cohort study method in patients with ischemic stroke (n = 33) in USU Hospital. Interventions: the intervened  variable were the cost of patient therapy and calculating the difference in claims of INA-CBGs with the cost of patient therapy. Main outcome measures: the main measurement in this study was quality of life with European Quality of Life - 5 Dimensions Three Level (EQ5D3L). Results:  the results of this study indicate the total average cost of ischemic stroke inpatient therapy at the In patient Installation of USU Hospital in Medan obtained Rp 2,284,854 The average cost / rate incurred by the Hospital for ischemic stroke patients (n = 33) is still below the INA-CBGs claim rate. There was a relationship between the quality of life of ischemic stroke patients with diagnosis and comorbidities of patients (p = 0.004). The average quality of life (QoL) of ischemic stroke patients was obtained 0.7324 ± 0.2118. Conclusion: it could be concluded that the quality of life of ischemic stroke patients is classified as good 32 patients (96.96%).    


Author(s):  
Oleksandr Vostrotin

The article is devoted to the topical problem of psychology, neurology, and rehabilitation - the question of psychological features of behavior that have developed as a result of stroke. What psychological features arise as a result of ischemic stroke and how they affect the life quality of patients were analyzed. The role of factors influencing the psycho-emotional state and rehabilitati on potential of patients was shown.


Author(s):  
O.P. Onopriyenko

The high incidence and increase in disability among the population after a stroke is a topical problem worldwide in the second decade of the 21st century. Brain strokes, their complications (dementias, depression), place a heavy burden on the society of the country, the families of patients. Objective: To investigate the impact of psychogenic factors on the epidemiology of stroke in Brоvаry district of Kyiv region for the last 10 years, to compile statistics and to compare them with world and regional data of Kyiv region and Ukraine. Methods. The resources of PubMed (1990-2016) and UpToDate (2016) were used to write the review article. To address these issues and to improve the quality of care provided to patients in the Kyiv region, Brovary and Brovary district, an epidemiological study of stroke patients and its risk factors has been continued. We screened 771 patients with stroke in the angioneurology department of the Brоvаry Multidisciplinary Clinical Hospital of the Kyiv region for psycho-emotional depressive disorders in the acute and late recovery period of ischemic stroke using NIHSS scales, Bartel index, modified Rankin scale, RASS scale. Statistical analysis of the obtained data was performed using the Spearman correlation coefficient, multiple regression analysis, descriptive statistics methods. Results. The risk factors for depression in the early recovery period after ischemic stroke and the association of post-stroke depression (PSD) with the risk of recurrence have been identified. 771 stroke patients (13%) had anxiety-depressive syndrome: 436 (56%) man, 335 (44%) women. PSD has been found to be more pronounced in old people, female, single patients. The development of PSD is influenced by many factors, including severity of stroke, disease course, significant functional impairment and degree of disability, reduced cognitive, language functions, and dependence on outsiders. The more pronounced severity of PSD is related to the degree of functional dependence and language-cognitive status. Conclusions. The presence of PSD results in worst prognosis of stroke of functional and cognetiv renewal of patients, increases their dependence on an extraneous help, considerably worsens quality of life. The origin of PSD has multifactorial genesis, mostly psychogenicsocial factor, influences on the degree of functional dependence of patients, especially aphasia. Influence on risk factors will give an opportunity to prevent development of PSD will promote it to effective rehabilitation and prevantion of repeated ischemic stroke. Keywords: ischemic stroke, psychogenic factors, post-stroke depression, principles of rehabilitation, treatment, prevention.


2019 ◽  
Vol 7 (3) ◽  
pp. 232-237
Author(s):  
Hana Larasati ◽  
Theresia Titin Marlina

Background: stroke is a disorder of nervous system function that occurs suddenly and is caused by brain bleeding disorders that can affect the quality of life physical dimensions, social dimensions, psychological dimensions, environmental dimensions. Based on the result of Lumbu study (2015) the number of samples were 71 people collected data using the (WHOQOL-BREF). There were 56 people (78,9%) had the poor quality of life of post stroke. The mean of post-stroke quality of life domain was physical domain (45,27%), psychological domain (49,87%), social relations domain (48,15%) and environmental domain (50.01%). Objective: the purpose of the study was know the quality of life of the stroke patients in Outpatient Polyclinic of Private Hospital in Yogyakarta. Methods: used descriptive quantitative by using questionnaire test of purposive sampling system based on patients who have been affected of ischemic or hemorrhagic stroke before, number 30 respondents. Result: quality of life of stroke patient of medium physical dimension (67%), psychological dimension (71%), social dimension (67%), dimension good environment (63%). Conclusion: the quality of life of stroke patients of physical dimension, psychological dimension, and moderate social dimension, while the quality of life of stroke patients were good environmental dimension.   Keywords: Hemorrhagic stroke, ischemic stroke, quality of life


2018 ◽  
Vol 3 (3) ◽  
pp. 237-245 ◽  
Author(s):  
Benjamin Hotter ◽  
Inken Padberg ◽  
Andrea Liebenau ◽  
Petra Knispel ◽  
Sabine Heel ◽  
...  

Introduction Detailed data on the long-term consequences and treatment of stroke are scarce. We aimed to assess the needs and disease burden of community-dwelling stroke patients and their carers and to compare their treatment to evidence-based guidelines by a stroke neurologist. Methods We invited long-term stroke patients from two previous acute clinical studies ( n = 516) in Berlin, Germany to participate in an observational, cross-sectional study. Participants underwent a comprehensive interview and examination using the Post-Stroke Checklist and validated standard measures of: self-reported needs, quality of life, overall outcome, spasticity, pain, aphasia, cognition, depression, secondary prevention, social needs and caregiver burden. Results Fifty-seven participants (median initial National Institutes of Health Stroke Scale score 10 interquartile range 4–12.75) consented to assessment (median 41 months (interquartile range 36–50) after stroke. Modified Rankin Scale was 2 (median; interquartile range 1–3), EuroQoL index value was 0.81 (median; interquartile range 0.70–1.00). The frequencies for disabilities in the major domains were: spasticity 35%; cognition 61%; depression 20%; medication non-compliance 14%. Spasticity ( p = 0.008) and social needs ( p < 0.001) had the strongest impact on quality of life. The corresponding items in the Post-Stroke Checklist were predictive for low mood ( p < 0.001), impaired cognition ( p = 0.015), social needs ( p = 0.005) and caregiver burden ( p = 0.031). In the comprehensive interview, we identified the following needs: medical review (30%), optimization of pharmacotherapy (18%), outpatient therapy (47%) and social work input (33%). Conclusion These results suggest significant unmet needs and gaps in health and social care in long-term stroke patients. Further research to develop a comprehensive model for managing stroke aftercare is warranted. Clinical Trial Registration: clinicaltrials.gov NCT02320994.


Stroke ◽  
2016 ◽  
Vol 47 (suppl_1) ◽  
Author(s):  
Hetal Mistry ◽  
Madeline Levy ◽  
Meaghan Roy-O'Reilly ◽  
Louise McCullough

Background and Purpose: Orosomucoid-1 (ORM-1) is an abundant protein with important roles in inflammation and immunosuppression. We utilized RNA sequencing to measure mRNA levels in human ischemic stroke patients, with confirmation by serum ORM-1 protein measurements. A mouse model of ischemic stroke was then used to examine post-stroke changes in ORM-1 within the brain itself. Hypothesis: We tested the hypothesis that ORM-1 levels increase following ischemic stroke, with sex differences in protein dynamics over time. Methods: RNA sequencing was performed on whole blood from ischemic stroke patients (n=23) and controls (n=12), with Benjamini-Hochberg correction for multiple testing. Enzyme-linked immunosorbent assay was performed on serum from ischemic stroke patients (n=28) and controls (n=8), with analysis by T-test. For brain analysis, mice (n=14) were subjected to a 90-minute middle cerebral artery occlusion (MCAO) surgery and sacrificed 6 or 24 hours after stroke. Control mice underwent parallel “sham” surgery without occlusion. Western blotting was used to detect ORM-1 protein levels in whole brain, with analysis by two-way ANOVA. Results: RNA sequencing showed a 2.8-fold increase in human ORM-1 at 24 hours post-stroke (q=.0029), an increase also seen in serum ORM-1 protein levels (p=.011). Western blot analysis of mouse brain revealed that glycosylated (p=0.0003) and naive (p=0.0333) forms of ORM-1 were higher in female mice compared to males 6 hours post-stroke. Interestingly, ORM-1 levels were higher in the brains of stroke mice at 6 hours (p=.0483), while at 24 hours ORM-1 levels in stroke mice were lower than their sham counterparts (p=.0212). In both human and mouse data, no sex differences were seen in ORM-1 levels in the brain or periphery at 24 hours post-stroke. Conclusion: In conclusion, ORM-1 is a sexually dimorphic protein involved in the early (<24 hour) response to ischemic stroke. This research serves as an initial step in determining the mechanism of ORM-1 in the ischemic stroke response and its potential as a future therapeutic target for both sexes.


Author(s):  
Nada El Husseini ◽  
Daniel T Laskowitz ◽  
Amanda C Guidon ◽  
DaiWai M Olson ◽  
Xin Zhao ◽  
...  

Background: Post-stroke depression is common, yet little is known about factors associated with antidepressant use in this population Methods: Data from the multicenter, prospective Adherence eValuation After Ischemic stroke-Longitudinal (AVAIL) registry was used to identify patients with post-stroke depression and to describe factors associated with antidepressant use. The analysis was performed after 3 months in 1751 ischemic stroke patients who had been admitted to 97 hospitals nationwide; 12 month follow-up was available for 1637 patients. The Get with the Guidelines-Stroke database was used to collect baseline data. Patients were classified as depressed based on a self-report scale (the Patient Health Questionnaire-8; score range 0 to 24, score ≥10 indicating depression). Frequencies were compared with Pearson X 2 and unadjusted ORs were calculated. Results: The prevalence of post stroke depression was similar at 3 and 12 months (19% [331/1751] vs 17% [280/1637], respectively, p=0.17). Regardless of depression status, antidepressant use was higher at 12 months (16% [287/1751] vs 20% [334/1637], p=0.002). Antidepressant use was also higher at 12 months in depressed patients (25% [84/331] vs 35% [98/280], p=0.009). The odds of antidepressant use at 3 months was higher in women than men (OR 1.6, 95% CI 1.2-2.1), Whites vs. Blacks (OR 1.7, 95% CI 1.1-2.8), in patients with vs. without cognitive deficits (OR 1.6, 95% CI 1.2-2.1) and in those with more severe disabilities (mRS≥3 vs. mRS<3, OR 1.7, 95% CI 1.3-2.3). Use did not vary with educational level, marital status, living situation, medication insurance coverage, or stroke recurrence. Similar trends were present at 12 months, except with higher use in those with recurrent stroke or TIA (OR 2.1, 95% CI 1.4-3.1). Conclusion: Three-quarters of depressed stroke patients at 3-months and nearly two-thirds at 12 months were not receiving antidepressants. Regardless of depression status, utilization of antidepressants after 3 and 12 months varied based on gender, race/ethnicity, cognitive status, disability level, and after 12-months, stroke recurrence. The reasons for the apparent underuse of antidepressants in patients with prevalent post-stroke depression require further study.


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