scholarly journals Review of role of jasad bhasma in management of shwetapradar

2018 ◽  
Vol 6 (02) ◽  
Author(s):  
Snehal Sambhaji Sawant ◽  
Anjali Jadhav
Keyword(s):  
Inflammatory Disease ◽  
Vaginal Discharge ◽  
Fungal Infections ◽  
Reproductive Age ◽  
Common Condition ◽  
Medical Interventions ◽  
Inflammatory Conditions ◽  
Child Bearing ◽  
Gynecological Diseases

Shwetapradar i.e leucorrhoea, also known as vaginal discharge is one of the major problems encountered in gynaecological practice. It is a very common condition that has been experienced by most women of all ages especially in child bearing or reproductive age. It may be due to various causes like Pelvic inflammatory disease , fungal infections, cervicitis, anaemia, diabetes etc. The disease mainly has complaints like yonistrav, yonikandu, yonishula, katishula. Usually its a non-pathological symptom secondary to inflammatory conditions of vagina or cervix and wants no medical interventions but it is significant if it is profuse, foul smelling, chnged in its color and consistency and blood stained. The white discharge is however caused by the presence of infection in any of these tissues and a variety of other factors. Bahya and abhyantar chikitsa  are described in ayurveda. In ayurved , metal based preparations that is bhasmas are indicated for the treatment of several gynecological diseases . According to Rasa Tarangini, Jasad bhasma in management of shwetapradar for its properties. KEYWORDS: Shwetapradar, yonigatastrav , yonikandu , jasad bhasma . 

scholarly journals Prevalence of Bacterial Vaginosis in Females of Child-Bearing Age and Utility of pH and Whiff Test in Diagnosis

2020 ◽  
pp. 51-56
Author(s):  
Fakhar Uddin ◽  
Faiza Zeeshan ◽  
Rakhshanda Younus ◽  
Haleema Yasmin ◽  
Saima Bugti ◽  
...  
Keyword(s):  
Bacterial Vaginosis ◽  
Vaginal Discharge ◽  
Local Population ◽  
Cross Sectional Study ◽  
Reproductive Age ◽  
Chi Square ◽  
Cross Sectional ◽  
Child Bearing ◽  
Chi Square Test ◽  
The Mean

Background: To determine the prevalence of bacterial vaginosis among females of reproductive age and assessment of the effectiveness of pH and the Whiff test in its diagnosis. Methods: This was a cross-sectional study. A total of 100 subjects were included, coming with a complaint of vaginal discharge. The bacterial vaginosis was diagnosed by using the Nugent scoring system, Whiff and pH tests. The prevalence was calculated by descriptive statistics and using the Chi-square test and results were shown in percentages and mean with standard deviation. Results: The estimated prevalence of bacterial vaginosis among the local population of females of child-bearing age was found to be 39%. The mean age of females with bacterial vaginosis was 33.33±10.46 years. The Whiff test was positive in 89.74% cases, while pH was elevated in 94.87% females with bacterial vaginosis. Conclusion: Bacterial vaginosis is a frequent cause of vaginal discharge in females of reproductive age in Pakistan. The diagnosis can be easily made by using Whiff and pH tests even at resource-poor settings. Keywords: Bacterial vaginosis, Child-bearing age, pH test, Whiff test.

scholarly journals Review of Clinical Studies on Karnini Yonivyapad vis-a-vis Cervical Erosion

2021 ◽  
pp. 64-70
Author(s):  
Tiwari Richa ◽  
Pushpalatha Buduru ◽  
Bharathi K
Keyword(s):  
Side Effects ◽  
Clinical Studies ◽  
Vaginal Discharge ◽  
Age Groups ◽  
Reproductive Age ◽  
Common Condition ◽  
Women Of Reproductive Age ◽  
Secondary Infertility ◽  
External Application ◽  
Modern System

Cervical erosion is a most common condition seen in women of reproductive age groups. Its prevalence is between 50-85% of all the gynecological conditions. In modern system of medicine diathermy cauterization or cryosurgery are generally advised for treatment but these procedures have their own side effects and complications like excessive vaginal discharge, secondary infertility, bleeding per vagina, infection, stenosis etc.. So still it is one of the most troublesome diseases for patients as well as for gynaecologists. Due to the serious consequences of the disease it is the need of hour to develop an accurate therapy for pathological erosion. This is an attempt to throw some more light on the clinical studies on cervical erosion. On cervical erosion total eight clinical studies in PG level has been completed out at National Institute of Ayurveda, Jaipur. Out of eight clinical studies, five works on Kshara Karma Karma (application of caustics), two works on Agnikarma (cauterization), two works on Kushthadi churna, one work on kushthadi varti, one work on Virechana. The drugs and procedures used in the research studies have chedana, Bhedan, Sosahana, Lekhana, Shodhana, Shothaghna, Raktprasadana, Vrana Shodhana (ulcer cleansing), Vrana Ropana (ulcer healer), krimihara, Kushtaghna (anti-dermatosis), Kandughna (anti-pruritic) properties. Maximum studies are carried out on Bahya Parimarjana (external application).

Pelvic Inflammatory Disease

2009 ◽  
Vol 2 (9) ◽  
pp. 517-521
Author(s):  
Alexander Hodson
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Female Genital Tract ◽  
Reproductive Age ◽  
Common Condition ◽  
Women Of Reproductive Age ◽  
Infection And Inflammation ◽  
Female Genital

Pelvic inflammatory disease (PID), infection and inflammation of the upper female genital tract, is a common condition managed by General Practitioners (GPs). It accounts for one in 60 consultations in women of reproductive age. Early diagnosis, management and, if necessary, referral is essential to help prevent serious long-term complications such as ectopic pregnancy, infertility and chronic pelvic pain. This article outlines the causes, clinical features, treatment and follow-up of PID.

scholarly journals A comparative study of moxifloxacin versus combination of doxycycline and metronidazole for treatment of uncomplicated pelvic inflammatory disease

2019 ◽  
Vol 8 (5) ◽  
pp. 956
Author(s):  
Priyadharshini M. ◽  
Sarmila Nath ◽  
Gourisankar Kamilya ◽  
Raja Roy
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Vaginal Discharge ◽  
Visual Analogue Score ◽  
Treated Group ◽  
Vaginal Swab ◽  
Reproductive Age ◽  
Number Of Patients ◽  
Group B ◽  
Organism Identification

Background: Pelvic inflammatory disease (PID), a common condition among women of reproductive age caused by various aerobic and anaerobic organisms, may sometimes lead to complications like infertility, ectopic pregnancy and chronic pelvic pain. Moxifloxacin is a broad spectrum bactericidal antibiotic acting against many gram positive, gram negative aerobic organisms and anaerobes. Rapid absorption and high bioavailability allow single daily dosing and improves compliance. The present study was done to compare the clinical and microbiological outcomes in  PID patients treated with conventional doxycycline- metronidazole  and moxifloxacin therapy.Methods: Women with uncomplicated PID, randomized into two groups either received 400 mg single dose of moxifloxacin daily for 14 days (group A) or doxycycline 100 mg + metronidazole 500 mg twice daily for 14 days (group B). Temperature, TLC count, ESR, CRP, microbiological assessment, Visual analogue score for pain, vaginal discharge, dyspareunia and backache were noted. The bacteriological cure was assessed by high vaginal swab for organism identification by gram stain, 10% KOH and blood sample by ELISA.Results: Total 60 women were enrolled and randomized into two groups. There was significant reduction of CRP and improved TLC in the moxifloxacin treated group. Visual analogue scores for pain, vaginal discharge and malaise were significantly reduced in the group treated with moxifloxacin.  Nausea, vomiting, metallic taste, dyspepsia and diarrhoea were complained by a significant number of patients of doxycycline + metronidazole group, in contrast to the patients receiving moxifloxacin.Conclusions: Moxifloxacin 400 mg once daily, is effective and safe for treatment of PID.

scholarly journals PPARγ Agonists: Emergent Therapy in Endometriosis

2021 ◽  
Vol 14 (6) ◽  
pp. 543
Author(s):  
Alexandre Vallée ◽  
Jean-Noël Vallée ◽  
Alain Le Blanche ◽  
Yves Lecarpentier
Keyword(s):  
Uterine Cavity ◽  
Reproductive Age ◽  
New Agents ◽  
Reproductive Age Women ◽  
Gynecological Diseases ◽  
Pparγ Agonists ◽  
Adhesion And Invasion

Endometriosis is one of the major gynecological diseases of reproductive-age women. This disease is characterized by the presence of glands and stroma outside the uterine cavity. Several studies have shown the major role of inflammation, angiogenesis, adhesion and invasion, and apoptosis in endometriotic lesions. Nevertheless, the mechanisms underlying endometriotic mechanisms still remain unclear and therapies are not currently efficient. The introduction of new agents can be effective by improving the condition of patients. PPARγ ligands can directly modulate these pathways in endometriosis. However, data in humans remain low. Thus, the purpose of this review is to summarize the potential actions of PPARγ agonists in endometriosis by acting on inflammation, angiogenesis, invasion, adhesion, and apoptosis.

scholarly journals Gestagens in the treatment of endometriosis

2018 ◽  
Vol 64 (1) ◽  
pp. 54-61 ◽  
Author(s):  
Tatiana A. Fedotcheva ◽  
Nikolai L. Shimanovskiy
Keyword(s):  
Cancer Cells ◽  
Molecular Genetic ◽  
Reproductive Age ◽  
Antiproliferative Effect ◽  
Target Cells ◽  
Gynecological Diseases ◽  
Cervical Cancer Cells ◽  
Molecular Genetic Characterization

Endometriosis occurs in 10% of females of reproductive age and ranks third among gynecological diseases, being one of the causes of infertility. The success of endometriosis treatment depends on individually selected therapy based on molecular-genetic characterization of the patient endometrial tissue. The review addresses the mechanisms of endometriosis development and the role of gestagens in the pathogenesis of this disease. We describe the genetic and epigenetic mechanisms of endometriosis development, which lead to resistance to endogenous progesterone, a key link in the pathogenesis of endometriosis. Because gestagen monotherapy is considered as first-line treatment, we analyze the gestagen properties that underlie the indications for their use in endometriosis. In particular, gestagen should have high gestagenic activity and an antiproliferative effect on target cells. An original domestic drug, an oral gestagen Gestobutanoil based on 17a-acetoxy-3b-butanoyloxy-6-methyl-pregna-4,6-dien-20-one (AMP-17), is promising for clinical use. The gestagenic activity of AMP-17 in the Clauberg-McPhail test is 102-fold higher than that of progesterone. AMP-17 has a pronounced antiproliferative effect on estrogen-dependent targets, such as breast cancer cells, cervical cancer cells, etc.

scholarly journals A study in a teritary centre for clinical assessment of pelvic inflammatory disease risk among women attending outpatient department

2017 ◽  
Vol 6 (9) ◽  
pp. 3823
Author(s):  
Sowmya D. ◽  
Sowjanya D.
Keyword(s):  
Risk Factors ◽  
Confidence Interval ◽  
Pelvic Inflammatory Disease ◽  
Birth Control ◽  
Inflammatory Disease ◽  
Odds Ratio ◽  
Vaginal Discharge ◽  
Reproductive Age ◽  
P Value ◽  
Factors Associated

Background: Pelvic inflammatory disease (PID) is associated with major medical and economic consequences for women of reproductive age. Identification of the risk factors associated with PID is crucial to efforts for prevention of these consequences. This study is done to evaluate the risk factors for PID in women attending OPD at Gangori hospital.Methods: This Study is an observational study, Conducted in Department of Obstetrics and Gynecology, Gangori hospital, SMS Medical College, Jaipur, From January 2015 to June 2015. Risk factors of PID were assessed in 70 women with PID (study group) and then it was compared with 70 controls attending the Women's Clinic at the same institution. Significance of difference in proportion in various variables of PID in both the group was inferred by odd’s ratio and Chi-square test. Logistic regression analysis was used to adjust for confounding variables.Results: A total of 70 women with PID and an equal number of controls were included. Cases were significantly younger than controls (p<0.001). The women were mainly of lower socioeconomic status. Risk factors identified by bivariate analysis were less than secondary level education, Odds ratio [OR] 5.29; (95% confidence interval: 1.680 to 16.675) P value 0.005. Parity >0, Odds ratio 2.521 (95% CI: 1.140 to 5.577) P value 0.033. Spontaneous abortion >0, Odds ratio 3.11 (95% CI: 1.311 to 7.362) P value 0.015. Lack of a birth control method, Odds ratio 7.18 (95% confidence interval: 3.091 to 16.662) p value<0.001. younger than 18 years at age of first sex, Odds ratio 2.84 (95% CI: 1.404 to 5.753) P value 0.006. Sex during the previous menses Odds ratio 5.39 (95% CI: 2.317 to 12.529) P value <0.001. Vaginal discharge/bleeding, Odds ratio 5.84 (confidence interval 2.717 to 12.578) P value <0.001. With multivariate analysis to control for confounders the risks still identified were sex during the previous menses, parity >0, lack of contraception, vaginal discharge and age at first sex.Conclusions: Identification of the risk factors associated with PID is most important effort for prevention of the disease and its sequelae. Educating the women, encouraging the use of condoms and other methods of contraception for PID prevention, sexually transmitted disease prevention and also birth control. Another finding is that, it is better to avoid coitus during the menses.

scholarly journals Gram stain and Giemsa stain as a rapid diagnostic tool for diagnosis of vaginal infections” in Western Nepal

2017 ◽  
Vol 5 (1) ◽  
pp. 5
Author(s):  
Kishor Bajracharya ◽  
Narinder Kaur ◽  
Sushama Suresh Pant
Keyword(s):  
Bacterial Vaginosis ◽  
Vaginal Discharge ◽  
Specific Treatment ◽  
Vaginal Swab ◽  
Giemsa Stain ◽  
Reproductive Age ◽  
Vaginal Infections ◽  
Medical College ◽  
Child Bearing ◽  
Litmus Paper

Abstract: Introduction: Infective vaginitis accounts for about 90% of all the cases of vaginal discharge in the women of reproductive age group. This includes triad of bacterial vaginosis, candidiasis and trichomoniasis. Method: The study was carried out in Lumbini Medical College and Teaching Hospital, Palpa, Nepal for a time period of 4 months. Total 125 high vaginal swabs from posterior fornix of vagina were collected from November 2014 to February 2015 in the department of Obstetrics and Gynecology, in the patients complaining of vaginal discharge. PH of the vaginal discharge was also determined by using litmus paper. Gram’s and Giemsa stain of vaginal swab smear were done to diagnose Bacterial vaginosis, Candidiasis and Trichomoniasis. Age, parity and pregnancy status of the patients were noted. Result: Out of 125 patient, bacterial vaginosis was found in 16% and candidiasis in 37%.Candidiasis and bacterial vaginosis were observed in child bearing sexually active women. Surprisingly bacterial vaginosis was not observed in pregnant women. Trichomoniasis infection was present in one case (0.8%) while severe invasive Candidiasis was observed in one woman. Conclusion: A definitive diagnosis can easily be made by Gram’s and Giemsa stain and microscopic examination of high vaginal swab. This may help in specific treatment and  prevent associated morbidity and  recurrence. Key words: Bacterial vaginosis, candidiasis, high vaginal swab, Gram’s stain, Giemsa stain.      

scholarly journals Gestagens in the treatment of endometriosis

2018 ◽  
Vol 64 (1) ◽  
pp. 54-61
Author(s):  
Tatiana A. Fedotcheva ◽  
Nikolai L. Shimanovskiy
Keyword(s):  
Cancer Cells ◽  
Molecular Genetic ◽  
Reproductive Age ◽  
Antiproliferative Effect ◽  
Target Cells ◽  
Gynecological Diseases ◽  
Cervical Cancer Cells ◽  
Molecular Genetic Characterization

Endometriosis occurs in 10% of females of reproductive age and ranks third among gynecological diseases, being one of the causes of infertility. The success of endometriosis treatment depends on individually selected therapy based on molecular-genetic characterization of the patient endometrial tissue. The review addresses the mechanisms of endometriosis development and the role of gestagens in the pathogenesis of this disease. We describe the genetic and epigenetic mechanisms of endometriosis development, which lead to resistance to endogenous progesterone, a key link in the pathogenesis of endometriosis. Because gestagen monotherapy is considered as first-line treatment, we analyze the gestagen properties that underlie the indications for their use in endometriosis. In particular, gestagen should have high gestagenic activity and an antiproliferative effect on target cells. An original domestic drug, an oral gestagen Gestobutanoil based on 17a-acetoxy-3b-butanoyloxy-6-methyl-pregna-4,6-dien-20-one (AMP-17), is promising for clinical use. The gestagenic activity of AMP-17 in the Clauberg-McPhail test is 102-fold higher than that of progesterone. AMP-17 has a pronounced antiproliferative effect on estrogen-dependent targets, such as breast cancer cells, cervical cancer cells, etc.

scholarly journals Clinical Findings of Pelvic Inflammatory Diseases among women in Reproductive Age

2021 ◽  
Vol 7 (1) ◽  
pp. 52-55
Author(s):  
Ismat Ara Laizu ◽  
Laila Anjuman Banu ◽  
Fowzia Abul Fayez
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Vaginal Discharge ◽  
Inflammatory Diseases ◽  
Clinical Findings ◽  
Reproductive Age ◽  
Age Group ◽  
College Hospital ◽  
Medical College ◽  
Reproductive Age Group

Background: Pelvic Inflammatory disease is a very common gynaecological condition among the women in reproductive age group. Objectives: The purpose of the present study was to find out the clinical findings of Pelvic inflammatory diseases among the women during reproductive age group. Methodology: This cross-sectional study was carried out in the Department of Obstetrics and Gynaecology at Mymensingh Medical College Hospital, Mymensingh, Bangladesh from January 2008 to June 2009 for a period of one (01) and a half year. Women who were presented with pelvic inflammatory disease (PID) attended at the OPD of gynecology Department at Mymensingh Medical College Hospital, Mymensingh, Bangladesh were selected as study population. Detailed clinical history of each patient was taken and thorough physical examination was performed. Result: A total number of 300 cases were recruited. The mean age with SD was 30.3±9.57 years. Majority of the patients had tenderness in the lower abdomen which was 96(64.0%) cases. However, 152(50.7%) patients had vaginal discharge and 34(11.3%) patients had uterovaginal proplapse. However, cervical tear was present in 96(32.0%) cases and chronic cervicitis was present in 138(46.0%) cases. Conclusion: In conclusion most common clinical feature is lower abdominal tenderness followed by vaginal discharge. Journal of National Institute of Neurosciences Bangladesh, January 2021, Vol. 7, No. 1, pp. 52-55

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