Efficacy of Plaksha (Ficus lacor) Ointment in the Management of Non- Healing Ulcer W.R.T. Dustavrana

2020 ◽  
Vol 8 (05) ◽  
Author(s):  
P. B. Jondhale
Keyword(s):  
Traumatic Injury ◽  
Purulent Discharge ◽  
Infected Wound ◽  
Healing Ulcer ◽  
External Application ◽  
Zinc Supplement ◽  
History Of ◽  
Foul Smell ◽  
Healing Property ◽  
Wound Healing Property

ABSTRACT   Chronic infected wound or non healing ulcer is a commonly encountered problem faced in surgical practice . wound healing property is most important pharmacological activity of Plaksh or Ficus lacor described by acharya Charaka and Bhavprakash . A 55 yrs old male patient of non healing ulcer having history of traumatic injury on right leg medially above the ankle joint .wound was irregular with hyper keratonized edges , purulent discharge with foul smell , itching , redness with inflammation. wound was cleaned with normal saline with aseptic precautions and malhar or ointment was used as external application for dressing on every day for one month and on alternate day for half month . Malhar or ointment was prepared on the basis of ‘Ras taranngini’, an ancient compendium .  vitamin c,  B complex and zinc supplement was given orally. At the end of one and half month wound was healed with healthy granulation tissue ,purulant discharge and foul smell was totally absent.

Formulation and Efficacy of Plaksha (Ficus lacor) Ointment in the Management of Non-Healing Ulcer

2021 ◽  
pp. 5680-5682
Author(s):  
Jayshree V. Changade ◽  
Anil H. Ulemale ◽  
P.B. Jondhale
Keyword(s):  
Wound Healing ◽  
Regulatory Mechanism ◽  
Stem Bark ◽  
Purulent Discharge ◽  
Infected Wound ◽  
Healing Ulcer ◽  
Zinc Supplement ◽  
Foul Smell ◽  
Healing Property ◽  
Wound Healing Property

Chronic infected wound or non healing ulcer is commonly encountered problem faced in surgico-clinical cases. Wound healing property is most important pharmacological activity of Plaksh or Ficus lacor described by acharya Charaka and Bhavprakash, in an ancient compendia. A male patient aged 55 years, having non healing ulcer on right leg medially above the ankle joint due to trauma, reported to OPD. Wound was irregular with hyper keratinized edges, purulent discharge with foul smell, itching, redness and inflammation. Wound was cleaned with normal saline aseptically and ‘malhar’ or ointment which was prepared by using stem bark of Ficus lacor, was applied locally every day, for thirty days followed by alternate day for next fifteen days. ‘Malhar’ or ointment was prepared as per the formulation mentioned in ‘Ras tarangini’, an ancient compendia. Vitamin C, B complex and Zinc supplement was given orally. After forty five days, wound healed with healthy granulation tissue, purulent discharge and foul smell was totally absent .Bark contains phytochemicals like tannins, polyphenols caffiec acid. It possesses antioxident, anti-inflammatory, antibacterial, astringent activities. Caffeic acid have regulatory mechanism on glucose metabolism in diabetes.

Multiple subluxations and comminuted fracture of the cervical spine in a sheep

2015 ◽  
Vol 43 (01) ◽  
pp. 44-38
Author(s):  
C.-C. Lin ◽  
K.-S. Chen ◽  
Y.-L. Lin ◽  
J. P.-W. Chan
Keyword(s):  
Cervical Spine ◽  
Pain Perception ◽  
Cervical Vertebrae ◽  
Traumatic Injury ◽  
Spinal Reflexes ◽  
Spine Trauma ◽  
Blunt Force Trauma ◽  
Comminuted Fracture ◽  
History Of ◽  
The Right

SummaryA 5-month-old, 13.5 kg, female Corriedale sheep was referred to the Veterinary Medicine Teaching Hospital, with a history of traumatic injury of the cervical spine followed by non-ambulatoric tetraparesis that occurred 2 weeks before being admitted to the hospital. At admission, malalignment of the cervical spine with the cranial part of the neck deviating to the right was noted. Neurological examinations identified the absence of postural reactions in both forelimbs, mildly decreased spinal reflexes, and normal reaction to pain perception tests. Radiography revealed malalignment of the cervical vertebrae with subluxations at C1–C2 and C2–C3, and a comminuted fracture of the caudal aspect of C2. The sheep was euthanized due to a presumed poor prognosis. Necropsy and histopathological findings confirmed injuries of the cervical spine from C1 to C3, which were consistent with the clinical finding of tetraparesis in this case. This paper presents a rare case of multiple subluxations of the cervical spine caused by blunt force trauma in a young sheep. These results highlight the importance of an astute clinical diagnosis for such an acute cervical spine trauma and the need for prompt surgical correction for similar cases in the future.

Wound healing property of isolated compounds from Boesenbergia kingii rhizomes

2016 ◽  
Vol 184 ◽  
pp. 42-48 ◽  
Author(s):  
Teeratad Sudsai ◽  
Chatchai Wattanapiromsakul ◽  
Supinya Tewtrakul
Keyword(s):  
Wound Healing ◽  
Healing Property ◽  
Wound Healing Property

scholarly journals A 15 year old male with continuous dull pain in the maxillary left central incisor

2018 ◽  
Vol 11 (2) ◽  
pp. 145
Author(s):  
Mst. Mahbuba Kafia Parvin ◽  
Mohammad Ali Asgor Moral ◽  
Md. Shamsul Alam ◽  
Gokul Chand Kundu
Keyword(s):  
Medical History ◽  
Male Patient ◽  
Dental Treatment ◽  
Traumatic Injury ◽  
Sinus Tract ◽  
Gingival Tissue ◽  
Central Incisor ◽  
Dull Pain ◽  
Root Area ◽  
History Of

<p><span>This article has no abstract. The first 100 words appear below:</span></p><p>A 15 year old male patient came to the Department with the complaint of continuous dull pain on his upper left central incisor. He also gave a history of traumatic injury when he was eight years old for which he didn't undergo any dental treatment. He had noncontributory medical history. On extraoral examination, no abnormality was detected. Intraoral examination revealed there was no sign of caries, no crown discoloration, no swelling and no sinus tract was present. Gingival tissue and tooth were intact. On palpation, the patient felt mild pain on the root area of affected tooth. On percussion, dull percussion note was present.</p>

scholarly journals Characterization and Applications of Leaf Extracts of Hemigraphis Alternate

2019 ◽  
Vol 9 (1S6) ◽  
pp. 108-114
Keyword(s):  
Wound Healing ◽  
Crude Extract ◽  
Leaf Extract ◽  
Cellular Migration ◽  
Leaf Extracts ◽  
Ic50 Value ◽  
The Gift ◽  
Healing Property ◽  
Low Cytotoxicity ◽  
Wound Healing Property

Natural products carry out various capabilities and a lot of them have thrilling and useful organic activities. The gift take a look at turned into undertaken to analyze the bioactive compounds and the pharmacological capacity of leaf extract of Hemigraphis alternata. The presence of numerous compounds become characterized by way of FTIR and GCMS. ROS effect and wound recuperation assets have been analyzed and it discovered that crude extract is greater powerful inhibiting ROS manufacturing and it has high wound healing property with properly cellular migration in dose based way. The cytotoxic nature of leaf extract also analyzed with the aid of MTT assay and it suggests low IC50 value of 329.95 µG/ml. The result discovered that the crude extract of H.Alternata leaf is a great wound healer with low cytotoxicity.

scholarly journals A Rare Case of Vault Angiofibroma

2021 ◽  
Vol 10 (16) ◽  
pp. 1177-1178
Author(s):  
Jayanthi R. ◽  
Iysverya G.T ◽  
Nishanthi Chandru
Keyword(s):  
Female Patient ◽  
Rare Case ◽  
Vital Signs ◽  
Vaginal Vault ◽  
Vaginal Examination ◽  
Speculum Examination ◽  
Normal Limits ◽  
Surgical Menopause ◽  
History Of ◽  
Foul Smell

A 52-year-old female patient, para 2 live 2, who attained surgical menopause 10 years back, presented to the outpatient department (OPD) with complaints of white discharge per vagina for 6 months, which was watery in consistency and was not associated with foul smell or itching vulva. She had history of hysterectomy done for fibroid uterus 10 years back. On examination, she was afebrile and vital signs were within normal limits. Per abdomen examination, was normal, while, per speculum examination revealed a watery discharge per vaginum. The per vaginal examination revealed a firm, non-tender, globular mass felt arising from the vaginal vault and the mass did not bleed on touch. A globular mass of size 3 x 4 cms, pinkish white in colour, was seen occupying the whole of the vaginal vault with curdy white precipitates in the vaginal rugosities as well as over the mass.

scholarly journals Scrofuloderma: A Diagnosis to Bear in Mind in the Western World

2019 ◽  
Vol 32 (4) ◽  
pp. 313
Author(s):  
Mariana Batista ◽  
Barbara Ferreira ◽  
Gonçalo Cruz ◽  
Américo Figueiredo
Keyword(s):  
Periodic Acid ◽  
Previous History ◽  
Complete Response ◽  
Purulent Discharge ◽  
Western World ◽  
Periodic Acid Schiff ◽  
Cutaneous Tuberculosis ◽  
Immunodeficiency Virus ◽  
History Of ◽  
Polymerase Chain

The incidence of tuberculosis has been increasing worldwide. Contrarily, a recent decrease in Portugal has been reported. Cutaneous tuberculosis comprises a low percentage of all cases. We report a 70-year-old female with a 2-month-history of painful, nodular, suppurative lesions in the groin area, bilaterally. Previous history was remarkable for Human Immunodeficiency Virus infection and stage-IIIB cervical cancer. A skin biopsy, stained with periodic acid–Schiff and Fite’s stain, polymerase chain reaction on purulent discharge and mycobacterial culture of the skin were performed, leading to the diagnosis of scrofuloderma. Tuberculostatic therapy was initiated and complete response was observed. This case depicts an uncommon variant of tuberculosis, highlighting the need for awareness of the cutaneous variants of tuberculosis that, although rare, can still present in the clinic today.

scholarly journals Wound healing effect of different extracts of Centaurea pterocaula

2019 ◽  
Vol 14 (1) ◽  
pp. 9-16 ◽  
Author(s):  
Barış Ötün ◽  
Ufuk Mercan Yücel
Keyword(s):  
Wound Healing ◽  
Healing Process ◽  
Punch Biopsy ◽  
Pathological Examination ◽  
Positive Contribution ◽  
Healing Property ◽  
Wound Healing Effect ◽  
New Drug Development ◽  
Ethyl Acetate Extracts ◽  
Wound Healing Property

In this study, the effect of different extracts of Centaurea pterocaula were evaluated on 6 mm wound created by punch biopsy on the rat back. The leaves of the plant were powdered and extracted with distilled water, methanol, n-hexane and ethyl acetate. Extracts were obtained in the form of pomade with vaseline and applied topically to the wounds. The wound measurements performed on day 0, 2, 4, 6, 8, 10 and 12 and the histo-pathological examination performed on day 12. The n-hexane extract had an accelerating effect on wound healing and made a positive contribution to the healing process. In conclusion, C. pterocaula has a promising future for new drug development studies by its wound healing property.

scholarly journals 186. Risk Factors for Extended Spectrum β-Lactamase Bacteremia and External Application of a Clinical Prediction Tool

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S113-S114
Author(s):  
Jacqueline Burnell ◽  
Rebecca Fallis ◽  
Peter Axelrod ◽  
Daniel Mueller
Keyword(s):  
Risk Factors ◽  
Antibiotic Therapy ◽  
Klebsiella Oxytoca ◽  
Significant Risk ◽  
University Hospital ◽  
Prediction Tool ◽  
External Application ◽  
The Past ◽  
Extended Spectrum ◽  
History Of

Abstract Background Extended spectrum β-lactamase (ESBL) bacteria are resistant to many antibiotics, which increases the risk of inadequate early antibiotic therapy. A previous single-center study had created a prediction tool to assist clinicians in identifying patients at risk for ESBL bloodstream infections. The purpose of our research project was to assess validity of this tool while also identifying risk factors for ESBL bacteremia within our own institution, which would allow for assessment of alternative prediction tools. Methods We performed a retrospective chart review of adult patients admitted to an urban university hospital who were found to have bacteremia with Escherichia coli, Klebsiella pneumoniae, and/or Klebsiella oxytoca between October 2016 and April 2018. Demographics and comorbidities were assessed, along with other potential risk factors including exposure to antibiotics and hospitalizations within the past 6 months. Results A total of 214 instances of bacteremia were identified and 14% were due to ESBL organisms. Risk factors for ESBL bacteremia in our cohort included history of positive culture for ESBL (RR = 5.9) or MRSA (RR = 3.5) and antibiotic usage in the past 6 months (RR = 2.3). Patients with ESBL bacteremia were hospitalized longer (mean 16 days vs. 6 days for non-ESBL), received longer durations of antibiotic therapy (11.7 days vs. 5.3 days), and were exposed to greater numbers of different antibiotics (1.9 vs. 0.7) in the previous 6 months. Multivariate logistic regression showed that history of prior ESBL infection (OR 14.7, CI 1.8–120) and increasing number of different antibiotic classes administered in the prior 6 months (OR 4.3, CI 1.7–11.2) were significant risk factors for ESBL bacteremia. The previously created prediction tool did not sufficiently differentiate higher and lower risk for ESBL bacteremia in our cohort. Conclusion Although risk factors were similar, the previously derived stepwise prediction tool did not predict ESBL bacteremia in our external cohort. Point-based prediction modeling might better assess risk across institutions. Additionally, the number of different antibiotics received was associated with risk for ESBL bacteremia and should be investigated further. Disclosures All authors: No reported disclosures.

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