scholarly journals Epidemiology of ovarian cancer in Kazakhstan (2013-2018)

2020 ◽  
Vol 56 (2) ◽  
pp. 9-11
Author(s):  
E. K. Kukubasov ◽  
A. R. Satanova ◽  
R. O. Bolatbekova ◽  
D. B. Kaldibekov ◽  
А. А. Kurmanova ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Western Europe ◽  
Malignant Tumors ◽  
Age Groups ◽  
Incidence Rates ◽  
Preventative Measures ◽  
Age Related ◽  
Working Age ◽  
East Kazakhstan ◽  
The Republic

Relevance: According to Globocan 2018, ovarian cancer (OC) ranks 18th among all other cancers affecting women around the world. More than 295,414 new cases of OC were reported only in 2018. The incidence is low in Western Europe and is high in Latvia, Poland, Lithuania, Estonia, Russia, and Kazakhstan. In 2018, ovarian malignancies ranked 8th (3.1%) in Kazakhstan among all malignant tumors. At that, there are no clearly recognized preventative measures to ensure the early detection of OC. 70% of ovarian malignancies are detected at stage III-IV. The purpose of this study was to conduct a comparative analysis and assessment of the dynamics of the prevalence of OC in the Republic of Kazakhstan in 2013-2018. Results: The analysis of age-related OC incidence in Kazakhstan showed the presence of ovarian malignancies in all age groups, with a marked increase by the age of 65-69 years. The majority of patients were women of the working age. Differences were found in the incidence rates by regions of the country. In the study period, the incidence was high in Qostanai, Pavlodar, and North Kazakhstan regions (northern part of the country) and Almaty. The incidence was below the national average in Atyrau, Jambyl, and South Kazakhstan regions (southern and western parts of the country). Recent years have witnessed a sharp increase in OC incidence in East Kazakhstan and Karaganda regions. Conclusion: The analysis of OC prevalence in the Republic of Kazakhstan and by regions showed an increase in OC incidence. There is a marked increase in OC detection in the northern areas of the country and a decrease in the number of cases in the south.

scholarly journals Epidemiology of ovarian cancer in Kazakhstan (2013-2018)

2020 ◽  
Vol 56 (2) ◽  
pp. 7-8
Author(s):  
E. K. KUKUBASOV ◽  
A. R. SATANOVA ◽  
R. O. BOLATBEKOVA ◽  
D. B. KALDIBEKOV ◽  
А. А. KURMANOVA ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Western Europe ◽  
Incidence Rates ◽  
Malignant Tumours ◽  
Preventative Measures ◽  
Age Related ◽  
Northern Areas ◽  
Working Age ◽  
East Kazakhstan ◽  
The Republic

Relevance: According to Globocan 2018, ovarian cancer (OC) ranks 7th among all other cancers affecting women around the world. 295,414 new cases of OC were reported only in 2018. The incidence in Western Europe is low. The incidence in Latvia, Poland, Lithuania, Estonia, Russia, as well as in Kazakhstan is high. In 2018, ovarian malignancies ranked 8th (3.1%) in Kazakhstan among all malignant tumours. At that, there are no clearly recognised preventative measures to ensure the early detection of OC. 70% of ovarian malignancies are detected at stage III-IV. The purpose of this study was to conduct a comparative analysis and assessment of the dynamics of the prevalence of OC in the Republic of Kazakhstan in 2013-2018. Results: The analysis of age-related OC incidence in Kazakhstan showed the presence of ovarian malignancies in all age groups, with a marked increase by the age of 65-69 years. The majority of patients were women of the working age. Differences were found in the incidence rates by regions of the country. In the study period, the incidence was high in Qostanai, Pavlodar, and North Kazakhstan regions (northern part of the country) and Almaty. The incidence was below the national average in Atyrau, Jambyl, and South Kazakhstan regions (southern and western parts of the country). Recent years have witnessed a sharp increase in OC incidence in East Kazakhstan and Karaganda regions. Conclusion: The analysis of OC prevalence in the Republic of Kazakhstan and by regions showed an increase in OC incidence. There is a marked increase in OC detection in the northern areas of the country and a decrease in the number of cases in the south.

Marked Increase in Incident Gynecomastia: A 20-Year National Registry Study, 1998 to 2017

2020 ◽  
Vol 105 (10) ◽  
pp. 3134-3140 ◽  
Author(s):  
Trine Koch ◽  
Elvira V Bräuner ◽  
Alexander S Busch ◽  
Martha Hickey ◽  
Anders Juul
Keyword(s):  
Age Groups ◽  
Population Based ◽  
Incidence Rates ◽  
National Registry ◽  
Registry Study ◽  
Age Related ◽  
Danish Health ◽  
Increased Risk ◽  
National Patient ◽  
First Time

Abstract Context Gynecomastia, the proliferation of mammary glandular tissue in the male, is a frequent but little-studied condition. Available prevalence data are based on selected patient populations or autopsy cases with their inherent bias. Objective The objective of this work is to evaluate the age-related incidence and secular trends in gynecomastia in the general population. Design An observational, 20-year national registry study was conducted. Setting This population-based study used nationwide registry data. Participants Participants included all Danish males (age 0-80 years) with a first-time diagnosis of gynecomastia. Main Outcome Measures All Danish males (age 0-80 years) were followed up for incident diagnosis of gynecomastia in the Danish National Patient Registry from 1998 to 2017 using the International Codes of Diseases, 10th revision, and the Danish Health Care Classification System. Age-specific incidence rates were estimated. The hypothesis tested in this study was formulated prior to data collection. Results Overall, a total 17 601 males (age 0-80 years) were registered with an incident diagnosis of gynecomastia within the 20-year study period, corresponding to 880 new cases per year and an average 20-year incidence of 3.4 per 10 000 men (age 0-80 years). The average annual incidence was 6.5/10 000 in postpubertal males age 16 to 20 years and 4.6/10 000 in males age 61 to 80 years, with a respective 5- and 11-fold overall increase in these 2 age groups over the 20-year period. Conclusions The incidence of gynecomastia has dramatically increased over the last 20 years, implying that the endogenous or exogenous sex-steroid environment has changed, which is associated with other adverse health consequences in men such as an increased risk of prostate cancer, metabolic syndrome, type 2 diabetes, or cardiovascular disorders.

scholarly journals Alimentary-dependent prevalence in children of different age groups (on the example, of the industrial center of the Irkutsk region)

2020 ◽  
Vol 99 (10) ◽  
pp. 1139-1144
Author(s):  
Inna V. Myl’nikova ◽  
Olga G. Bogdanova
Keyword(s):  
Age Groups ◽  
Incidence Rates ◽  
The Body ◽  
Linear Regression Models ◽  
Software Module ◽  
Adaptive Capabilities ◽  
Age Related ◽  
Irkutsk Region ◽  
Quality Of Medical Care ◽  
Industrial Center

Aim of the study. Analysis of the dynamics of the alimentary-dependent prevalence in children from various age groups in the industrial center. Materials and methods. The study was conducted retrospectively according to official statistical reporting. The total and primary incidence in children and adolescents in the city of Angarsk was estimated for 6 years (2013-2018). Age-specific features of the incidence in children were analyzed over 3 years (2016-2018). Relative indices of the incidence were calculated (per 1000 population of the corresponding age), characteristics of the time series: the average annual absolute increment; the rate of average annual growth (decrease); linear regression models were built using the Excel software module. Results. An analysis of the primary morbidity of alimentary-dependent pathology in children of different ages showed that its structure is characterized by a predominance of diseases of the digestive, endocrine systems, and blood. Moreover, in young children, blood diseases are most pronounced. Assessment of the dynamics of alimentary-dependent diseases in children aged 0-14 and 15-17 years revealed multidirectional trends. In children aged 0-14 and 15-17 years, the presence of pronounced trends to a decrease in the incidence of the pathology of the digestive system was revealed. The differences are that pronounced trends in the increase in the incidence are observed in children aged 0-14 years - in the frequency of obesity, in children 15-17 years old - in the frequency of endemic goiter. Discussion. The obtained values of the regression analysis allow predicting an increase in the frequency of diseases of the thyroid gland associated with iodine deficiency in children aged 0-14 years, obesity - in 15-17 year adolescents. Differences in the frequency of these nosological forms depending on the age of the children can be presumably due to changes in eating behavior, the influence of heredity, and the adaptive capabilities of the body. The incidence rates of alimentary-dependent pathology depend on the quality of medical care and the geochemical characteristics of the territory of residence. Conclusion. The study revealed the age-related characteristics of alimentary-dependent pathology and concretized the directions for improving medical and preventive activities.

scholarly journals Invention of ovarian cancer in Nišav district

2021 ◽  
Vol 46 (3) ◽  
pp. 117-119
Author(s):  
Biljana Kocić
Keyword(s):  
Ovarian Cancer ◽  
Incidence Rate ◽  
Malignant Disease ◽  
Malignant Tumors ◽  
Direct Method ◽  
Linear Trend ◽  
Incidence Rates ◽  
Education Of Women ◽  
Reduce Risk ◽  
Descriptive Method

Introduction : Ovarian cancer is the eighth most common malignant disease in women in the world, accounting for 3.4% of all malignant tumors in women. It has the highest lethality among gynecological malignancies. The aim of this paper was to analyze the incidence of this malignancy in the Nisava district in the period 1999-2018. years. Material and method: Descriptive method applied. The population registry for cancer of the Institute of Public Health in Nis was the source of the data. Raw and standardized incidence rates per 100,000 women were calculated. Standardization was performed by the direct method. The linear trend of the incidence rate was calculated. Results: In the structure of malignant diseases in women, ovarian cancer accounts for 5%. The average annual standardized incidence rate is 13.5. In the observed twenty-year period, an increase in the linear trend of incidence rates is registered. The highest standardized rate was recorded in 2016 (20.4), and the lowest in 2002 (10.1). The disease is not registered under the age of fifteen, and is most common in the age group of 70-74. There is a statistically significant increase in the trend of standardized incidence rates with age. The highest standardized incidence rate is recorded in the municipality of Svrljig (18.5) and the lowest in the municipality of Merošina (7.2). Conclusion: The registration of an unfavorable trend in the incidence of ovarian cancer indicates a lack of adequate primary and secondary prevention. It is necessary to effectively implement preventive measures and education of women in order to reduce risk factors and early detection of the disease.

scholarly journals Estimated varicella incidence on the basis of a seroprevalence survey

2001 ◽  
Vol 127 (3) ◽  
pp. 501-507 ◽  
Author(s):  
M. P. MUÑOZ ◽  
A. DOMÍNGUEZ ◽  
L. SALLERAS
Keyword(s):  
Disease Incidence ◽  
Severe Disease ◽  
Age Distribution ◽  
Age Groups ◽  
Incidence Rates ◽  
Delta Method ◽  
Effective Vaccine ◽  
Varicella Zoster ◽  
Age Related ◽  
Seroprevalence Data

Varicella is a disease caused by varicella-zoster virus. It is transmitted via the respiratory route, is highly communicable and mainly affects young children. An effective vaccine is now available, whose routine use is advised by health authorities in the USA and which can prevent severe disease, although breakthrough infections do occur. In deciding whether or not to include a vaccine in the routine vaccination schedule, knowledge of the morbidity of the disease in question is fundamental. Although reporting of varicella is compulsory in Catalonia, doctors only have to report the weekly number of cases diagnosed, and not their age distribution. Given that recent data on the prevalence of the infection in Catalonia according to age groups is available, it was considered that, using these data, an estimation of age-related incidence could be made.The objective of the present study was to estimate the incidence of varicella in Catalonia on the basis of the available seroprevalence data. A curve was fitted to the observed prevalence and point prevalence estimates for all ages were obtained. The incidence was derived by smoothed prevalence for each of these age groups. Estimated variance of the estimated incidence was obtained by the delta method. Predicted prevalence in the 0–4 years age group was calculated by the smoothed prevalence.The model that best fitted the sample prevalence was the exponential function. The estimated number of varicella cases in this study was 46419 (95% CI 40507–52270). As the population in Catalonia in 1996 was 6090040, the previous results give an incidence rate of 762·2 per 100000 persons/year with their 95% CI (666·1–858·3).The method described may be applied to the study of incidence rates in relation to the prevalence of diseases if we accept that the infection produces permanent immunity; the risk of mortality is the same for infected and non-infected subjects and that the disease incidence and population remain constant in time.

Incidence and Survival of Brain Tumors: A Population-Based Study

1988 ◽  
Vol 74 (3) ◽  
pp. 243-252 ◽  
Author(s):  
Milena Sant ◽  
Paolo Crosignani ◽  
Bianca Maria Bordo ◽  
Giancarlo Nicola ◽  
Mario Bianchi ◽  
...  
Keyword(s):  
Nervous System ◽  
Choroid Plexus ◽  
Incidence Rate ◽  
Survival Probability ◽  
Malignant Tumors ◽  
Age Groups ◽  
Incidence Rates ◽  
Benign Tumors ◽  
Probability Of Survival ◽  
Age Class

Since 1976 the Lombardy Cancer Registry (RTL) has recorded all malignant tumors and the benign tumors of the nervous system, bladder and liver occurring in the Varese province. The aims of this report are: to describe age-specific incidence rates of the different oncotypes of primary nervous system tumors (PNSTs) and to analyze the duration of survival of the patients according to the histotype of the neoplasm. From 1976 to 1981, the RTL recorded 498 PNST: 213 tumors of glial origin, 132 tumors of mesodermal tissues, 15 tumors of multipotential cell origin, 37 tumors of nerve roots, 8 of vascular origin, and 54 PNST in which the histotype was not specified. For tumors of glial origin, the 60–69 year age class showed the highest incidence rate: 16 per 100,000/year. The incidence rate of tumors of mesodermal tissues reached the maximum value of 7.9 per 100,000/year in the age group of 75 years and over. Tumors of multipotential cell origin had a maximum incidence of 2.2 in the 60–69 year age class. The probability of survival at 5 years after diagnosis was computed by the method of Kaplan and Meier (15), and the log rank procedure was used to test statistical differences among survivors. Tumors of glial origin, excluding ependymomas and papillomas of choroid plexus, had a 5-year survival probability of 14%. Age (categorized in ≤50 and > 50 years) and histologic grade (grades I+II and grades III+IV) were analyzed as prognostic factors for tumors of glial origin: a younger age was the most predictive prognostic factor in grade I+II tumors (probability of survival = 53% in the group ≤50 years vs 0 in the group > 50 years; p < 0.005). In the less differentiated tumors there were no differences between the two age groups. Patients with tumors of mesodermal tissues had a 5-year probability of survival of 83%. Subjects younger than 50 years had a probability of survival of 95%, whereas older patients had a probability of 79%. For the other oncotypes, the 5-year survival probability was: 50% for tumors of multipotential cell origin, 63% for ependymomas and papillomas of the choroid plexus, 64% for tumors of vascular derivation, and 21% for PNST with not specified histotype.

scholarly journals Gender and demographic features of the labor market of the Republic of Tuva: trends and prospects

POPULATION ◽  
2021 ◽  
Vol 24 (2) ◽  
pp. 120-130
Author(s):  
Organa Natsak
Keyword(s):  
Labor Market ◽  
Age Groups ◽  
Female Population ◽  
Regional Labor Market ◽  
Active Population ◽  
Regional Labor ◽  
Working Age ◽  
The Republic ◽  
Gender Profile ◽  
Demographic Features

The article analyzes the gender and demographic features of the labor market of the Republic of Tuva: the structure and rate of employment and unemployment in gender dimension and historic retrospect covering the period of Tuva People's Republic (1921-1944), the Soviet and post-Soviet stages of history. On the basis of statistical data it is shown that from 1945 began predominance of female population in the demographic structure of the republic that is characteristic of modern Tuva. The author makes an attempt to give a historic explanation of this turn. The article shows changes in the ratio of male to female population of Tuva from 1931 to 2020 using various statistic sources and data. In the features of the gender profile of the regional labor market, the author identifies demographic, socio-cultural and economic factors determining it, in particular, the reasons for withdrawal of men from the economically active population in certain age groups. The article substantiates the thesis that, despite the steady trend of reducing unemployment in the republic in 2017, 2018, 2019, the issue of male employment remains acute. It also shows the level of demographic burden on the working-age population of the Republic of Tuva connected with the specifics of reproductive behavior of the population of the republic, namely, high birth rates, as well as the emerging trend of increasing the proportion of people over the working age due to the positive dynamics of increasing life expectancy in the republic.

scholarly journals Epidemiological analysis of the malignant tumors of the larynx in Belarus over 2000–2019

2021 ◽  
Vol 18 (4) ◽  
pp. 83-92
Author(s):  
I. D. Shlyaga ◽  
Zh. V. Kaliadzich ◽  
S. A. Ivanov ◽  
A. A. Yaumenenka
Keyword(s):  
Rural Areas ◽  
Rural Population ◽  
Malignant Tumors ◽  
Morbidity Rate ◽  
Slow Increase ◽  
Maximal Increase ◽  
Significant Difference ◽  
Working Age ◽  
Working Age Population ◽  
The Republic

Objective. To analyze basic medico-statistical indices of the morbidity rates of the malignant tumors of the larynx in the Republic of Belarus.Materials and methods. Data of the Belarusian Cancer Register on all detected cases of the malignant tumors of the larynx in the Republic of Belarus over 2000-2019 served as the material of the study. The following rates were studied: age standardized morbidity, gross intensive morbidity, morbidity separately in the general population and working age population, in urban and rural population, males and females. All epidemiological indices for the periods 2000-2005 and 2015-2019 in the country and across the regions of the Republic of Belarus were compared.Results. The age standardized morbidity rate in Belarus increased from 4.2 cases/year per 100,000 population in 2000 to 5.8 in 2019. The gross intensive morbidity rate increased from 5.5 to 7.3, respectively. An increase in the morbidity rate from 4.0 in 2000 to 4.3 in 2019 was noted in the working age population. The gross intensive morbidity rates in males were on average 33.9 times higher than in females, and in the urban population – 1.7 times lower than those in the rural population. The maximal increase in the morbidity rate was registered in the working age population of rural areas – by 60.3% during the monitored period. A statistically significant increase in the morbidity rate was noted in the city of Minsk. The morbidity rates registered in Minsk were statistically significantly lower than those in the republic. In other regions, there was no significant difference in the morbidity rates and growth dynamics from the indices in Belarus as a whole.Conclusion. Malignant tumors of the larynx are characterized by a slow increase of the morbidity rate for the last 20 years in Belarus. The observed epidemiological trends deter

scholarly journals Epidemiological features of malignant mesothelioma in the Republic of Belarus

2021 ◽  
Vol 18 (3) ◽  
pp. 315-326
Author(s):  
K. A. Hutsich ◽  
L. F. Levin
Keyword(s):  
Malignant Mesothelioma ◽  
Rural Areas ◽  
Western Europe ◽  
General Structure ◽  
Cumulative Risk ◽  
Incidence Rates ◽  
Peak Incidence ◽  
The Republic ◽  
Cement Manufacturing ◽  
The City

Based on the data of the Belarusian Cancer Register for 2000–2019 the dynamics and structure of incidence of mesothelioma in the Republic of Belarus are studied. We calculated incidence rates, age-standardized incidence rates, taking into account the gender and place of residence of patients, cumulative risk. The analysis of the structure was carried out both for the whole population and separately for men and women, as well as for the urban and rural population.We detected that the incidence rates of malignant mesothelioma in the Republic of Belarus are significantly lower than those in the Western Europe region and the Central and Eastern European region. For the period from 2000 to 2019 the dynamics of the incidence rates of mesothelioma in the Republic is characterized by a moderate tendency to decrease, and in the general structure of the incidence rate both among men and among women, pleural mesothelioma is the dominant localization. The population of regions where asbestos-cement manufacturing is located has no higher risk of developing malignant mesothelioma in comparison with population levels.The estimated incidence of mesothelioma in men is 2 times higher than the incidence of women, and this excess is independent of age differences between these two populations. The highest incidence rates for men are observed at the age of 75–79 years, while the peak incidence for men living in the city falls at the earlier age – 70–74 years. Among women living both in the city and in rural areas, the peak incidence falls at the age of 80–84 years.

Prediction Mortality Rate Due to the Road-Traffic Accidents in Kazakhstan

2020 ◽  
Author(s):  
Nurbek IGISSINOV ◽  
Alma AUBAKIROVA ◽  
Galiya ORAZOVA ◽  
Gulnur Akpolatova ◽  
Saltanat URAZOVA ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Traffic Accidents ◽  
Road Traffic ◽  
Age Group ◽  
Road Traffic Accidents ◽  
The Road ◽  
Age Related ◽  
Working Age ◽  
The Republic ◽  
Population Mortality

Background: As a result of the road traffic accidents 1.25 mln. of working-age people die each year on the roads. Frequency of the RTA is 11 times higher in our country than in Europe, that influence on demographic and economic situation in the republic. Creation of the math modeling and prediction of traffic mortality rate in Kazakhstan will allow to develop measure on its decrease. Methods: Short-term dotted prediction of population mortality level of Kazakhstan was used, in particular – methods of regressive analysis. General prognosis throughout the country up to 2021 was made on the basis of data for 1999-2018. The more relevant method for prediction is exponential function taking into account the features of mortality rate level trend. Results: Prediction of traffic fatalities without division into the age-related groups for 2019 is 2132±181 case with a probability 2/3. Expected levels for 2020-2027 cases, for 2021-1927 cases. Annual mortality decrease rate according to the 0-19 age-related at an average is 6.4% among men and 5.8% among women, according to age group as a whole – by 6.2%; from 20 up to 64 age related group – 5.1 % on all population category; older 65 age –group is by 2.2 %, 3.7 % among men, 2.9% among women as a whole. Conclusion: In the foreseeable future the number of traffic deaths in Kazakhstan will tend to decrease at a slower pace. Mortality rates due to road traffic accidents among working-age men will be 3 times higher than women in this age group.

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