scholarly journals Morphological characteristics of changes in the squamous epithelium of the upper part of the digestive tract in model organisms in the settings of provoked carcinogenesis

2021 ◽  
Vol 62 (4) ◽  
pp. 35-42
Author(s):  
V. Shestakova ◽  
L. Nigmatullina ◽  
I. Atadzhanov ◽  
S. Donskov ◽  
Yu. Kozlovskaya ◽  
...  

Relevance: Noticeable spreading of malignant neoplasms of upper section of digestive system and the worsening of these patients’ quality of life in case of late diagnostics stimulate the development of protocols for early detection of precancerous changes. The purpose of the study was to investigate the morphological characteristics of changes in the squamous epithelium of the upper part of the digestive tube in model organisms under provoked carcinogenesis when exposed to substances with proven carcinogenic activity. Methods: 40 female nonlinear white rats obtained from the Orekhovo-Zuevsky urban settlement veterinary station were used as model organisms. The rats were divided into 4 equal groups. The first control group was not exposed to any specific influences. In groups 2-4, the rats underwent sedation and mechanical scarification microtraumatization of the oral mucosa. Then, they were applied twice a week by 0.9% NaCl solution (control group 2), 1% aqueous solution of dimethyl sulfoxide (DMSO, Akrikhin, Russia) (control group 3), or 1% aqueous solution of DMSO containing 0.1 mg/ml 4-nitroquinoline-N-oxide (4- NQO, Acros Organics, USA) (experimental group 4). Results: The cytological picture associated with chronic trauma to the mucous membrane of the upper digestive tract was characterized by nonspecific reactions: inflammation, hyper- and parakeratosis, and atrophic changes. There were no statistically significant differences in the frequency of such changes between the experimental and control groups. Specific changes in squamous epithelium towards a precancerous state in the experimental group with chronic exposure to a substance with carcinogenic activity occurred significantly more often than in the control groups (p <0.05), as proven by the results of comparative histological verification. Conclusion: Cytological study can be offered for clinical study as a screening tool for precancerous oropharynx and upper esophagus conditions

Author(s):  
Hasanul Arifin Zul And Masitowarni Siregar

This thesis is focused on the investigation of the effect of applying animal cartoon pictures on students’ achievement in writing narrative text. This study aims to find whether applying animal cartoon pictures significantly affect the students’ writing achievement or not. The data in this study were obtained by administering a written test. The population was the 2015/2016 first year (grade XI) of SMA Swasta Nusantara Lubuk Pakam and 66 students were taken as the sample by using random sampling. The sample was divided into two groups, experimental and control groups. The experimental group was taught by applying animal cartoon pictures while the control group without animal cartoon pictures (x = lecturing). The data were taken the scores from the pre-test and post-test to both experimental and control groups. These data were analyzed by using t-test. The result of computing the t-test obviously showed that t-observed is higher than t-table (5.21 >1,67) with the degree of freedom 64 (df =N-2) at the level significance 0,05 one tail test. It showed that the application of animal cartoon pictures significantly affected the students of SMA Swasta Nusantara Lubuk Pakam achievement in writing narrative text.


Author(s):  
Meryanti Napitupulu And Anni Holila Pulungan

This study was conducted as an attempt to discover the effect of applying Demonstration Method on students’ achievement in speaking skill. It was an experimental research. The subject was students of Grade XII, Vocational High School (Sekolah Menengah Kejuruan: SMK), which consisted of 79 students. The research was divided into two groups: experimental and control groups. The instrument used to collect the data was speaking test. To obtain the reliability of the test, the writer applied Kuder Richardson 21 formula. The result of the reliability was 0.7, and it was found that the test was reliable. The data were analyzed by using t-test formula. The analysis showed that the scores of the students in the experimental group were significantly higher than the scores of the students in the control group at the level of significant m = 0.05 with the degree of freedom (df) 77, t-observed value 8.9 > t-table value 1.99. The findings indicate that using Demonstration Method significantly affected the students’ achievement in speaking skill. So, English teachers are suggested to use Demonstration Method in order to improve students’ achievement in speaking skill.


2021 ◽  
pp. 104973152110014
Author(s):  
Siu-ming To ◽  
Xiaoyu Liu

Purpose: Using a nonrandomized control group pretest–posttest assessment, this study aimed to examine the outcomes of community-based youth empowerment initiatives that were informed by design thinking. Method: A total of 553 youth living in Hong Kong were recruited to participate in this study. Among them, 213 youth self-selected to join the experimental group, and 340 youth joined the two control groups. Multivariate analysis of covariance and post hoc group comparisons were used to examine the differences among the three groups at the posttest assessment. Results: The results indicate a positive improvement in creative self-efficacy among participants of the experimental group compared to the two control groups. Significant differences were also found between the experimental group and the second control group in terms of youth–adult partnerships and youth empowerment in the community. Conclusion: Youth empowerment programs informed by design thinking may reinforce self-efficacy beliefs by encouraging youth to bring about innovations in their community.


1970 ◽  
Vol 7 (1) ◽  
pp. 89-98 ◽  
Author(s):  
Md Sharif Hossain ◽  
Fatema Begum

In Bangladesh some researchers have done several studies to find the correlation of simple diffuse goiter with arsenic level but no one conducted any study to find the differences of urinary iodine, urinary arsenic, radioiodine uptake, the thyroid stimulating hormone (TSH) and free thyroxin (FT4) levels between goitrous and non goitrous. That is why, in this research an attempt has been made to compare the urinary iodine, urinary arsenic, radioiodine uptake, TSH and FT4 levels between experimental group with simple diffuse goiter and healthy control group. In this study another purpose has also been made to find the associations between different pairs of variables for both experimental and control group. In this study we have tried to find the impacts of arsenic level on simple diffuse goiter. This is a case-control analytical study. The study is carried out in the Institute of Nuclear Medicine and Ultrasound, in collaboration with the thyroid out patient department of Bangabandhu Sheikh Mujib Medical University. A total of eighty five (85) subjects are included in the study. Among the 85 subjects, a sample of forty five is considered for experimental group with simple diffuse goiter and another sample of forty is considered for healthy control group without any thyroid disease. From the experimental results it has been found that, the arsenic levels, FT4 and radioiodine uptake levels at 2 hours between the experimental and control groups are significantly different but the urinary iodine levels, TSH levels and radioiodine uptake levels at 24 hours between the experimental and control groups are not statistically different. From the experimental results it has also been found that there is significant differentiation between experimental and controls groups in respect of association between different pairs of variables. In this study, another significant finding is that iodine deficiency is not only the factor of causing simple diffuse goiter, but arsenic level is also one of the most important factor of causing simple diffuse goiter. Key words: Iodine deficiency, Simple diffuse goiter, Urinary arsenic, Statistical analysis, Association, Experimental and Control groups  DOI = 10.3329/dujps.v7i1.1224 Dhaka Univ. J. Pharm. Sci. 7(1): 89-98, 2008 (June)


2017 ◽  
Vol 13 (1) ◽  
pp. 39
Author(s):  
Duriye Esra Angın

The purpose of this research is to investigate the effects of Dora the Explorer cartoon on the spatial concept acquisitions and spatial abilities of the preschool children. The study was carried out with 80, 60-71 month old children attending preschools. Post-test only control group model is used in the research in order to identify the existing phenomena in a controlled manner. “The Bracken Basic Concept Scale, Third Edition: Receptive (BBCSIII:R) Form Direction/Position Subscale” and two different “Spatial Ability Games” were used to assess children’s spatial concept acquisitions and spatial abilities. Independent sample t-test was used in order to compare the average of post-test scores of the children in the experimental and control groups. According to the findings, it is found that there is meaningful difference between scores of post-tests of direction/position subscale and spatial ability games score. Comparing the scores of post-test of direction/position subscale and spatial ability games of experimental and control groups, it was found that there was a meaningful differentiation in favor of experimental group.


2018 ◽  
Vol 12 (1) ◽  
pp. 128
Author(s):  
Samer Al-Hammouri

The purpose of this study is to investigate the effect of using Prezi on Al Zaytoonah students&rsquo; performance in French Language reading skill. To achieve the purpose of the study, a pre/post-test was constructed to measure students&rsquo; performance in French language reading skill. The sample of the study comprised 128 students from Al Zaytoonah University and was distributed into two sections, which were selected purposefully. The sample of the study was distributed into two groups (one experimental and one control groups). The experimental group&rsquo;s students were taught the reading skill using Prezi while the control groups&rsquo; students were taught using the traditional way. The sample of the study was 64 students in the experimental group and 64 students in the control group. Those groups were distributed into two purposefully selected sections in public schools in Amman. The results of the study showed a variance in the means of the achievement test according to group, it also showed that there were statistically significant differences on the achievement test due to the Strategy variable. There were statistically significant differences between using Prezi Strategy and the Current Strategy in favor of the Prezi Strategy, and there was no statistically significant difference in the students&rsquo; achievement due to gender. There was no statistically significant difference due to the interaction between gender and group. The researchers recommend that researchers focus on new teaching strategies and conduct more studies related this topic. They also recommend that other researchers conduct studies and focus on the role play strategy.


2018 ◽  
Vol 7 (2) ◽  
pp. 91-100
Author(s):  
Islam Namazian Doost ◽  
Soheila Tahmasbi

This study aims to investigate the possible effects of peripheral learning on elementary EFL learners’ grammar improvement: the case of prepositions of time and place. Two elementary classes were selected as experimental and control groups. Before beginning the treatment, a grammar test was administered to both the groups as a pre-test. Then, as treatment, the experimental group was exposed to realia, pictures, posters and texts, while the control group was not. After term-long treatment of 10 weeks, the two groups received the same grammar test as post-test. The results of t-test showed that the experimental group improved their grammar ability, i.e., knowledge of prepositions of time and place more than their friends in the control group. The finding of the study may open an optional path for teachers to include some peripheral materials in their teaching environment to further invest on unconscious learning abilities of the students.   Keywords: Peripheral learning, reposition of time, prepositions of place, grammar.


2019 ◽  
Vol 2 (2) ◽  
pp. 269
Author(s):  
Yoga Pratama

The objectives of this study were to find out whether or not there was significant improvement in writing and speaking achievements of the eighth grade students of SMPN1 Jarai after they were taught by using Sociogram, to find out whether or not there was significant improvement in each aspect of writing and speaking achievements of the eighth grade students of SMPN1 Jarai after they were taught by using Sociogram, to find out whether or not there was significant difference in writing and speaking achievements between the eighth grade students of SMP 1 Jarai who were taught by using Sociogram and those who were not, and to find out the perception of the eighth grade students of SMPN 1 Jarai after they were taught by using Socoiogram. In this paper, an experimental research method with pre and post test control group design was used with 70 students as the sample divided into two groups, experimental and control group. However, only the students of the experimental group were taught by using Sociogram. The obtained data were analyzed by using t-test. The students were given questionnaire to know their perceptions. The result showed that there was a significant difference in both students? writing and speaking achievements after they were tought by using Sociogram. Furthermore, it was found that there was a significant difference in students? writing and speaking achievement between the experimental and control groups. In conclusion, Sociogram improves the students? writing and speaking achievements.


Author(s):  
Mohammed bin Majed bin Shariah al - Shammari

The aim of this study was to identify the effectiveness of teaching role playing strategy in developing dialogue skills in the immortal language of the intermediate third grade students. To achieve the objectives of the study, the researcher used the semi-experimental method by designing the two equal groups. The sample contains 51 students, 26 students for the control group and 25 students for the experimental group. The researcher used the statistical treatments using the SPSS program, The study has resulted in The results showed that the level of dialogue skills on the student scale among the average third-grade students in the experimental and control groups was medium. The mean of the two groups was on all dialogue skills (2.23). The skill of expressing the opinion is one of the most common dialogue skills, (2.25), while the skill of listening and listening is second, with an average of (2.24), followed by self-esteem in third place with an average of 2.23. Finally, ). In addition, there were statistically significant differences at the level of α 0.05 0.05 in post-performance in all dialogue skills (self-esteem, good listening and listening, respect for others, expression of opinion). In the light of its findings, the researcher made a number of recommendations.


Author(s):  
Salim Ahmed Saif Al-rashdi

    The present study aimed at uncovering the effectiveness of employing the enrichment activities for mental thinking on the development of mathematical thinking and achievement among Grade 7 students. To achieve the research objectives, the researcher used the semi experimental design known as the design of the control group with the tribal and remote tests. In light of the experimental design, the average Grade 7 students tested the sample of the study in the second semester of 30 students who were divided into 15 students for the experimental group and 15 students for the control group after checking the validity and stability of the tools. The results showed that there was a statistically significant difference at (0.05) between the mean scores of the experimental and control groups in the cognitive achievement test related to the unit of Engineering in the second semester and the mathematical thinking test for the average of the experimental group. The results also showed a statistically significant difference) between the average scores of the experimental group students in the tribal and remote applications in the cognitive achievement test and the mathematical thinking test, and in favor of the average post-implementation. In the light of these results, the study presented a number of recommendations and suggestions.   ، ، ، ،


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