scholarly journals Optimization of Skin Moisturizer Formula Based on Fixed Oil (VCO, Olive Oil, and Jojoba Oil)

2021 ◽  
Vol 6 (2) ◽  
pp. 109-114
Author(s):  
Dita Nurlita Rakhma ◽  
Yuyun Nailufa ◽  
Yuli Ainun Najih ◽  
Hery Wahjudi
Keyword(s):  
Olive Oil ◽  
Natural Compounds ◽  
Physical Characteristics ◽  
Jojoba Oil ◽  
Test Results ◽  
Skin Ph ◽  
Significant Difference ◽  
Ph Range ◽  
Oil Type

Currently, formulations of skin moisturizers are derived from natural compounds. Fixed oils are known to have compounds that potential to be developed as skin moisturizers based on emollient mechanism. Therefore, this study aims to determine the effect of oil type on the physical characteristics of skin moisturizer creams. In this study, a skin moisturizer cream was formulated using three types of fixed oils: VCO (F1), Olive Oil (F2), and Jojoba Oil (F3). All formulas were tested for physical characteristics of pH, cream type, viscosity, spreadability, and homogeneity. The test results show that all formulas appropriate to the skin pH range,  have o/w type creams and homogeneous texture. In the results of the viscosity test, there was a significant difference (p<0.05) with the highest value of viscosity for F2 (16750 ± 250 cP) > F3 (14200 ± 346cP) > F1 (5833 ± 58 cP), while for spreadability test there were also significant differences (p<0.05) with the highest diameter for  F1 (5.8 ± 0.1 cm) = F3 (5.7 ± 0.2 cm) > F2 (4.3 ± 0.2 cm). Based on the results, it can be concluded that the type of oil can affect the physical characteristics of the moisturizer formula. F1 and F3 have better physical characteristics than F2. 

Perbedaan sensitivitas tetes telinga antibiotik terhadap Pseudomonas aeruginosa pada otitis media supuratif kronik

2012 ◽  
Vol 42 (2) ◽  
Author(s):  
Anton Budhi Darmawan ◽  
Dwi Utami Anjarwati
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Otitis Media ◽  
Chronic Suppurative Otitis Media ◽  
Test Results ◽  
Sectional Study ◽  
Suppurative Otitis Media ◽  
Number Of Patients ◽  
Significant Difference ◽  
Cochran Test ◽  
Post Hoc

Background: Chronic suppurative otitis media (CSOM) is one infectious disease of the middle ear, most commonly caused by Pseudomonas aeruginosa. A high number of patients come to the ENT outpatient clinic with active benign type of CSOM. The bacteria Pseudomonas aeruginosa is capable of producing biofilm which protects itself from penetration of antibiotics, and therefore creates resistance towards antibiotics and difficult to eradicate. Objective: The aim of this study was to compare the sensitivity levels of chloramphenicol, polymyxin-neomycin, cyprofloxacin and ofloxacine against Pseudomonas aeruginosa in patients with active benign type CSOM in ENT clinic. Method: The method used was across sectional study on 25 patients, from August 2010 until December 2010. Samples were taken withear swab and then put on sensitivity test to chloramphenicol, polymyxin-neomycin, cyprofloxacin andofloxacine using the diffusion disc method. The analysis used in this study was Cochran test. Results: Results showed a significant difference in sensitivity among chloramphenicol (38,70%), polymyxinneomycin(83,87%),cyprofloxacin(90,32%)andofloxacin(58,06%)withp=0,000(p<0,05).PostHocanalysisusing the Mc Nemar indicated that there were significant differences in sensitivity betweenpolymyxin-neomycin to chloramphenicol with p=0,000 (p<0,05), ciprofloxacin to chloramphenicol andciprofloxacin to ofloxacine with p= 0,002, but there were no significant differences between cyprofloxacinto polymyxin-neomycin with p=0,687, polymyxin-neomycin to ofloxacin p=0.057 and ofloxacin tochloramphenicol p=0,109.   There were significant differences in antibiotic ear dropssensitivity to Pseudomonas aeruginosa in patients with active benign type of CSOM. Cyprofloxacin andpolymyxin-neomycin were more sensitive than ofloxacin and chloramphenicol. Keywords: Pseudomonas aeruginosa, active benign type of chronic suppurative otitis media, antibioticear drops.  Abstrak :  Latar belakang: Otitis media supuratif kronik (OMSK) merupakan penyakit infeksi kronik telinga tengah yang sering dijumpai di klinik THT. Penyebab tersering OMSK adalah bakteri Pseudomonasaeruginosa. Pseudomonas aeruginosa mempunyai kemampuan untuk membentuk biofilm yangmelindunginya dari penetrasi antibiotik sehingga menimbulkan resistensi terhadap antibiotik dan sulituntuk eradikasinya. Tujuan: Untuk mengetahui perbandingan tingkat sensitivitas kloramfenikol,polimiksin-neomisin, ciprofloksasin dan ofloksasin terhadap isolat Pseudomonas aeruginosa padapasien OMSK benigna aktif di klinik THT RSMS. Metode: Metode yang digunakan adalah crosssectional terhadap 29 pasien OMSK di klinik THT RSMS periode bulan Agustus 2010 - Desember2010. Pengambilan sampel dilakukan dengan swab telinga. Uji sensitivitas terhadap kloramfenikol,polimiksin-neomisin, ciprofloksasin dan ofloksasin dilakukan dengan metode cakram secara difusi.Analisis yang digunakan dalam penelitian ini adalah Cochran dan analisis post hoc. Hasil: Didapatkansensitivitas kloramfenikol sebesar 38,70%, polimiksin-neomisin sebesar 83,87%, ciprofloksasin sebesar90,32% dan ofloksasin sebesar 58,06% dengan p=0,01 (P<0,05), yang menunjukkan adanya perbedaansensitivitas yang bermakna antara kloramfenikol, polimiksin-neomisin, ciprofloksasin dan ofloksasinterhadap Pseudomonas aeruginosa. Analisis post hoc menggunakan Mc Nemar menunjukkan bahwaterdapat perbedaan sensitivitas yang bermakna antara tetes telinga polimiksin-neomisin terhadapkloramfenikol, dan ciprofloksasin terhadap kloramfenikol p=0,000 (p<0,05), serta terdapat perbedaanyang bermakna antara tetes telinga ciprofloksasin terhadap ofloksasin, p=0,002, tetapi tidak terdapatperbedaan yang bermakna antara ciprofloksasin terhadap polimiksin-neomisin, p=0,687, polimiksinneomisinterhadap ofloksasin p=0,057, dan kloramfenikol terhadap ofloksasin p=0,109. Kesimpulan:Terdapat perbedaan sensitivitas yang bermakna tetes telinga antibiotik terhadap Pseudomonas aeruginosa pada pasien OMSK benigna aktif. Ciprofloksasin dan polimiksin-neomisin tetes telinga mempunyai sensitivitas yang lebih baik dibanding ofloksasin dan kloramfenikol. Kata kunci: Pseudomonas aeruginosa, otitis media supuratif kronik, tetes telinga antibiotik 

A STUDY OF CONDYLAR POSITION IN CENTRIC RELATION AND MAXIMAL INTERCUSPATION USING CONEBEAM TOMOGRAPHY

2019 ◽  
pp. 84-92
Author(s):  
Anh Chi Phan ◽  
Xuan Anh Ngoc Ho
Keyword(s):  
Dental Students ◽  
Cone Beam ◽  
Test Results ◽  
Reference Position ◽  
Centric Relation ◽  
Temporomandibular Joints ◽  
Significant Difference ◽  
Mandibular Fossa ◽  
Condylar Position ◽  
Cone Beam Tomography

Background: The condylar position discrepancy between centric relation and maximal intercuspation has been still a controversial issue. Aims: To compare the condylar position between centric relation and maximal intercuspation using cone-beam tomography in patients without temporomandibular joints disorder. Materials and methods: To assess the condylar position in centric relation and maximal intercuspation using cone-beam tomography on 40 fifth-year and sixth-year dental students of Hue University of Medicine and Pharmacy without temporomandibular joints disorder. The condylar positions are assessed following Sener classification (2009) and are compared between centric relation and maximal intercuspation using pairedsamples t-test and Mann-Whitney U-test. Results: Among 480 condye-to-fossa measurement pairs, there are 91.2% pairs having difference between two reference position but there is no significant difference. The condylar position at the superior of mandibular fossa has the greatest percentage in both centric relation and maximal intercuspation (43.8% in centric relation and 51.2% in maximal intercuspation). This greatest percentage is followed by the condylar position at posterior of mandibular fossa (32.5% in centric relation and 36.3% in maximal intercuspation). Lastly, the condylar position at the anterior of mandibular fossa has the fewest percentage (23.7% in centric relation and 12.5% in maximal intercuspation). Conclusion: There is no significant difference of condylar position between centric relation and maximal intercuspation in patients without temporomandibular joints disorder. Key words: Condylar position, centric relation, maximal intercuspation, cone-beam tomography

Sinonasal effects of external dacryocystorhinostomy

2021 ◽  
pp. 1-4
Author(s):  
H Eyigor ◽  
E A Cetinkaya ◽  
D T Coban ◽  
G Ozturk ◽  
Ö Erdem
Keyword(s):  
Mucociliary Clearance ◽  
Nasal Symptom ◽  
Ciliary Activity ◽  
Test Results ◽  
Saccharine Test ◽  
Significant Difference ◽  
Symptom Scores ◽  
Endoscopic Score ◽  
External Dacryocystorhinostomy

Abstract Objective External dacryocystorhinostomy is thought to cause mucociliary dysfunction by damaging the mucosa, in turn affecting ciliary activity and mucus quality. This study investigated the effect of external dacryocystorhinostomy on sinonasal function. Methods Patients scheduled for unilateral external dacryocystorhinostomy who underwent endoscopic nasal examination and paranasal sinus computed tomography were included in this study. A saccharine test was performed on the planned surgical side and the mucociliary clearance time was determined. The sinonasal quality of life was measured in all patients, pre-operatively and at six months post-operatively, using the Sino-Nasal Outcome Test-22. The Lund–Kennedy endoscopic score was also determined in all patients, both pre- and post-operatively. Results The study comprised 28 patients (22 females and 6 males). A statistically significant difference was found between the pre- and post-operative saccharine test results (p = 0.006), but not between the pre- and post-operative Sino-Nasal Outcome Test-22 scores (p > 0.05). Conclusion This study is one of only a few to investigate the effect of external dacryocystorhinostomy on sinonasal function. The results showed that external dacryocystorhinostomy impairs mucociliary clearance. The surgical procedure is well tolerated and does not significantly change nasal symptom scores.

Inter-Bolt Variability of Cotton Duck #4 and the Effects on Cigarette Ignition Propensity Test Outcome

1995 ◽  
Vol 13 (2) ◽  
pp. 127-140 ◽  
Author(s):  
Richard Jupe ◽  
Donald K. Shipley ◽  
William Z. Hudson ◽  
Joseph T. Wanna ◽  
Linda C. Greear
Keyword(s):  
Test Methods ◽  
Physical Parameters ◽  
Test Results ◽  
Astm Method ◽  
Significant Difference ◽  
Ignition Propensity

Two bolts of cotton duck fabric that meet military specifications and the purchasing guidelines described by the National Institute of Standards and Technology (NIST) for use as a substrate in "Test Methods for Quantifying the Propensity of Cigarettes to Ignite Soft Furnishings" were tested with smoldering cigarettes to determine the effect of inter-bolt variations on cigarette ignition propensity test outcome. The test was designed around an ASTM method that calls for the control of all known test variables, except for those inherent to the fabric's manufacture. The ignitability of each fabric was determined by testing two sets of 48 replications for each of two experimental cigarettes. The two bolts of cotton duck fabric showed a statistically significant difference in ignitions, independent of environmental and experimental fac tors. Two additional bolts of cotton duck #4 were analyzed. Cigarette ignition test results and the physical parameters of the additional bolts offer evidence that the NIST specifications are difficult to meet and further that test results are extremely sensitive to fabric properties.

scholarly journals Bioprospection and characterization of the amylolytic activity by filamentous fungi from Brazilian Atlantic Forest

2017 ◽  
Vol 17 (3) ◽  
Author(s):  
Paula Zaghetto de Almeida ◽  
Marita Gimenez Pereira ◽  
Caio Cesar de Carvalho ◽  
Paulo Ricardo Heinen ◽  
Luciana Sobrani Ziotti ◽  
...  
Keyword(s):  
Filamentous Fungi ◽  
Atlantic Forest ◽  
Rhizopus Oryzae ◽  
Residual Activity ◽  
Brazilian Atlantic Forest ◽  
Tropical Environments ◽  
Aspergillus Brasiliensis ◽  
Significant Difference ◽  
Initial Ph ◽  
Ph Range

Abstract Filamentous fungi are widely diverse and ubiquitous organisms. Such biodiversity is barely known, making room for a great potential still to be discovered, especially in tropical environments - which are favorable to growth and species variety. Filamentous fungi are extensively applied to the production of industrial enzymes, such as the amylases. This class of enzymes acts in the hydrolysis of starch to glucose or maltooligosaccharides. In this work twenty-five filamentous fungi were isolated from samples of decomposing material collected in the Brazilian Atlantic Forest. The two best amylase producers were identified as Aspergillus brasiliensis and Rhizopus oryzae. Both are mesophilic, they grow well in organic nitrogen-rich media produce great amounts of glucoamylases. The enzymes of A. brasiliensis and R. oryzae are different, possibly because of their phylogenetical distance. The best amylase production of A. brasiliensis occurred during 120 hours with initial pH of 7.5; it had a better activity in the pH range of 3.5-5.0 and at 60-75°C. Both fungal glucoamylase had wide pH stability (3-8) and were activated by Mn2+. R. oryzae best production occurred in 96 hours and at pH 6.5. Its amylases had a greater activity in the pH range of 4.0-5.5 and temperature at 50-65ºC. The most significant difference between the enzymes produced by both fungi is the resistance to thermal denaturation: A. brasiliensis glucoamylase had a T50 of 60 minutes at 70ºC. The R. oryzae glucoamylase only had a residual activity when incubated at 50°C with a 12 min T50.

KORELASI ANTARA HASIL TES MIKROSKOPIS DENGAN TES CEPAT MOLEKULER PADA PASIEN TUBERCULOSIS DAN MULTIDRUG RESISTEN TUBERCULOSIS DI RSUD Dr. H CHASAN BOESOIRIE TERNATE

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Andi Sitti Nur Afiah ◽  
Fera The
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Pulmonary Disease ◽  
Program Analysis ◽  
Rifampicin Resistance ◽  
Test Results ◽  
Chi Square ◽  
Significant Difference ◽  
Mdr Tb ◽  
Chi Square Test ◽  
Analytical Research

Tuberculosis (TB) is a pulmonary disease caused by Mycobacterium tuberculosis. Globally in 2018 theestimated number of people affected by TB was estimated at 10.0 million population and 484,000 cases ofmultidrug-resistant TB (MDR-TB). This study aims to determine the correlation between microscopic testresults with RMT on TB and MDR-TB patients at RSUD Dr. H Chasan Boesoirie Ternate. This type of researchis analytical research using a retrospective approach. The sample in this study were patients with suspected TBand MDR-TB who had performed microscopic tests and TCM in February – April at 2020 in the ClinicalPathology Laboratory of RSUD Dr. H Chasan Boesoirie Ternate, who met the inclusion and exclusion criteria.Data were analyzed using the SPSS program analysis was carried out in stages, namely by univariate andbivariate using chi-square test. From 100 samples, the results of RMT examination with TB suspects were 30rifampicin sensitive samples with 2 rifampicin resistance and 5 rifampin sensitive samples for TB MDR-TBsuspects RMT examination results. Chi-square test results obtained the value of p = 000 (p <0.05). There is stilla significant difference between the microscopic test results with RMT in TB and MDR-TB suspect patients atRSUD Dr. H Chasan Boesoirie Ternate.

Effects of diets rich in ghee or olive oil on cardiometabolic risk factors in healthy adults: A 2-period, crossover, randomized trial

2021 ◽  
pp. 1-30
Author(s):  
Susan Mohammadi Hosseinabadi ◽  
Javad Nasrollahzadeh
Keyword(s):  
Olive Oil ◽  
Dietary Intervention ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Density Lipoprotein ◽  
Dietary Fats ◽  
Lipoprotein Cholesterol ◽  
Apo B ◽  
Blood Samples ◽  
Significant Difference

Abstract This study aimed to evaluate the cardiovascular health-related effects of consuming ghee in the usual diet. Thirty healthy men and women were studied in a free-living outpatient regimen. The participants were instructed for the isocaloric inclusion of ghee or olive oil in their diets for 4 weeks using a randomized crossover design. At the end of run-in (baseline), 2-week wash-out, and interventions, fasting blood samples were drawn. In addition, 2-h postprandial blood samples were collected after ingestion of a meal containing olive oil or ghee at week 4 of each dietary intervention. Body weight was not different between the two interventions. Compared to the olive oil, the diet with ghee increased fasting plasma apolipoprotein-B (apo B) (0.09, 95% CI 0.02 to 0.17 g/L, p= 0.018) and non-high-density lipoprotein cholesterol (non-HDL-C) (0.53, 95% CI 0.01 to 1.05 mmol/L, p= 0.046) and low-density lipoprotein cholesterol did not differ significantly between diet groups (0.29, 95% CI –0.05 to 0.63 mmol/L, p= 0.092), but had no significant effect on total cholesterol/HDL-C ratio (0.75, 95% CI −0.24 to 1.74 mmol/L, p= 0.118). No significant difference was observed in fasting as well as 2-h postprandial plasma triacylglycerol, glucose, insulin, and plasminogen activator inhibitor-1 concentrations. This study showed that ghee which is predominantly saturated fats had an increasing effect on plasma apo B and non-HDL-C compared to olive oil, adding further evidence to the existing recommendations to replace dietary fats high in SFA with dietary fats high in unsaturated fats to reduce cardiovascular disease risk.

Could Be % MMEF and sGaw Determinant Diagnostic Parameters Between Partial Reversibility and Reversibility in Evaluating Short-Acting Bronchodilator Response?

2021 ◽  
Author(s):  
Gökhan Erdoğan ◽  
Elif Altuğ ◽  
Sacide Rana Işık ◽  
Levent Tabak
Keyword(s):  
Independent Predictor ◽  
Binary Logistic Regression ◽  
Threshold Value ◽  
Test Results ◽  
Binary Logistic Regression Model ◽  
Bronchodilator Response ◽  
Significant Difference ◽  
Post Hoc ◽  
The Relationship ◽  
Airway Conductance

INTRODUCTION: By examining the relationship between changes in maximum mild-expiratory flow( MMEF) and specific airway conductance(sGaw), parameters with the change in FEV1 when evaluating the spirometer test and the bronchodilator response, we investigated their diagnostic contribution to the bronchodilator response in those with partial responses to FEV1. METHODS: The retrospective study sample consists of data from 112 patients between Jun 1, 2019, and Feb 1, 2020 who applied to the pulmonary function laboratory with a pre-diagnosis of bronchial hyperreactivity as well as body plethysmography test performed together with the reversibility test. RESULTS: MMEF% and ▲sGaw were linearly correlated with ▲FEV1 (respectively r = 0.752; p <0.001, r = 0.611; p <0.001). While there was a significant difference between ▲MMEF% and ▲sGaw between reversible, partially reversible, and irreversible groups (P <0.001), there was no significant difference in ▲sGaw between partial reversible and reversible groups in post-hoc comparisons (P> 0.05). In the binary logistic regression model created between the partially reversible and reversible groups, demographic characteristics, MMEF% and ▲sGaw variables, ▲MMEF was an independent predictor [OR: 1.132; 95% CI (1.036-1.238), p = 0.006]. The 24% threshold for absolute reversibility or partial reversibility calculated with MMEF% was significant, indicating significance at 86.2% sensitivity and 80.8% specificity (AUC: 0.811, 95% CI: 0.686-0.936; p <0.001). This value we found defined 81% of the partially reversible group as reversible. DISCUSSION AND CONCLUSION: We observed that ▲sGaw alone didn' have a determinant contribution for determining reversibility in bronchodilator response, which showed partial reversibility with respect to FEV1 change. We believe that ▲MMEF% can be an independent predictor between these two groups and the calculated threshold value of 24% can be used as a criterion for determining the reversibility in cases where FEV1 is not determinant.

Interobserver Variability in Subclassification of Squamous Intraepithelial Lesions

1999 ◽  
Vol 123 (11) ◽  
pp. 1079-1084 ◽  
Author(s):  
Sherry L. Woodhouse ◽  
Janet F. Stastny ◽  
Patricia E. Styer ◽  
Mary Kennedy ◽  
Amy H. Praestgaard ◽  
...  
Keyword(s):  
Interlaboratory Comparison ◽  
Interobserver Variability ◽  
High Grade ◽  
Test Results ◽  
Squamous Intraepithelial Lesions ◽  
Papanicolaou Test ◽  
Management Guidelines ◽  
Significant Difference ◽  
Intraepithelial Lesion ◽  
Intraepithelial Lesions

Abstract Objective.—To determine whether, on a national cytology proficiency test, a competent cytologist can consistently distinguish grades of squamous intraepithelial lesions. Design.—Results for low- and high-grade squamous intraepithelial lesion referenced slides from the College of American Pathologists Interlaboratory Comparison Program in Cervicovaginal Cytology for 1996 and 1997 were analyzed including educational, nongraded vs graded validated slides. Results.—The discrepant rate between low- and high- grade lesions ranged from 9.8% to 15% for cytotechnologist, pathologist, laboratory, and all responses. There was a statistically significant difference in performance on graded, validated slides vs educational slides with better performance on validated slides. Conclusion.—This significant interobserver variability in subclassification of squamous lesions should be considered in management guidelines for abnormal Papanicolaou test results and implementation of national cytology proficiency testing.

scholarly journals The Use of Keyword Video Captioning on Vocabulary Learning Through Mobile-Assisted Language Learning

2017 ◽  
Vol 7 (4) ◽  
pp. 1 ◽  
Author(s):  
Hassan Saleh Mahdi
Keyword(s):  
Language Learning ◽  
Mobile Devices ◽  
Vocabulary Learning ◽  
Test Results ◽  
Video Captioning ◽  
Mobile Assisted Language Learning ◽  
Significant Difference ◽  
Post Test ◽  
Key Aspects ◽  
Teaching Pronunciation

Video captioning is a useful tool for language learning. In the literature, video captioning has been investigated by many studies and the results indicated that video captioning may foster vocabulary learning. Most of the previous studies have investigated the effect of full captions on vocabulary learning. One of the key aspects of vocabulary learning is pronunciation. However, the use of mobile devices for teaching pronunciation has not been investigated conclusively. Therefore, this paper attempts to examine the effect of implementing keyword video captioning on L2 pronunciation using mobile devices. Thirty-four Arab EFL university learners participated in this study and were randomly assigned to two groups (key-word captioned video and full captioned video). The study is an experimental one in which pre- and post-tests were administered to both groups. The results indicated that keyword captioning is a useful mode to improve learner’s pronunciation. The post test results indicate that there was no statistically significant difference between the two modes of captioning on vocabulary learning. However, learners at keyword video captioning performed better that full video captioning. 

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