Could Be % MMEF and sGaw Determinant Diagnostic Parameters Between Partial Reversibility and Reversibility in Evaluating Short-Acting Bronchodilator Response?

2021 ◽  
Author(s):  
Gökhan Erdoğan ◽  
Elif Altuğ ◽  
Sacide Rana Işık ◽  
Levent Tabak
Keyword(s):  
Independent Predictor ◽  
Binary Logistic Regression ◽  
Threshold Value ◽  
Test Results ◽  
Binary Logistic Regression Model ◽  
Bronchodilator Response ◽  
Significant Difference ◽  
Post Hoc ◽  
The Relationship ◽  
Airway Conductance

INTRODUCTION: By examining the relationship between changes in maximum mild-expiratory flow( MMEF) and specific airway conductance(sGaw), parameters with the change in FEV1 when evaluating the spirometer test and the bronchodilator response, we investigated their diagnostic contribution to the bronchodilator response in those with partial responses to FEV1. METHODS: The retrospective study sample consists of data from 112 patients between Jun 1, 2019, and Feb 1, 2020 who applied to the pulmonary function laboratory with a pre-diagnosis of bronchial hyperreactivity as well as body plethysmography test performed together with the reversibility test. RESULTS: MMEF% and ▲sGaw were linearly correlated with ▲FEV1 (respectively r = 0.752; p <0.001, r = 0.611; p <0.001). While there was a significant difference between ▲MMEF% and ▲sGaw between reversible, partially reversible, and irreversible groups (P <0.001), there was no significant difference in ▲sGaw between partial reversible and reversible groups in post-hoc comparisons (P> 0.05). In the binary logistic regression model created between the partially reversible and reversible groups, demographic characteristics, MMEF% and ▲sGaw variables, ▲MMEF was an independent predictor [OR: 1.132; 95% CI (1.036-1.238), p = 0.006]. The 24% threshold for absolute reversibility or partial reversibility calculated with MMEF% was significant, indicating significance at 86.2% sensitivity and 80.8% specificity (AUC: 0.811, 95% CI: 0.686-0.936; p <0.001). This value we found defined 81% of the partially reversible group as reversible. DISCUSSION AND CONCLUSION: We observed that ▲sGaw alone didn' have a determinant contribution for determining reversibility in bronchodilator response, which showed partial reversibility with respect to FEV1 change. We believe that ▲MMEF% can be an independent predictor between these two groups and the calculated threshold value of 24% can be used as a criterion for determining the reversibility in cases where FEV1 is not determinant.

Perbedaan sensitivitas tetes telinga antibiotik terhadap Pseudomonas aeruginosa pada otitis media supuratif kronik

2012 ◽  
Vol 42 (2) ◽  
Author(s):  
Anton Budhi Darmawan ◽  
Dwi Utami Anjarwati
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Otitis Media ◽  
Chronic Suppurative Otitis Media ◽  
Test Results ◽  
Sectional Study ◽  
Suppurative Otitis Media ◽  
Number Of Patients ◽  
Significant Difference ◽  
Cochran Test ◽  
Post Hoc

Background: Chronic suppurative otitis media (CSOM) is one infectious disease of the middle ear, most commonly caused by Pseudomonas aeruginosa. A high number of patients come to the ENT outpatient clinic with active benign type of CSOM. The bacteria Pseudomonas aeruginosa is capable of producing biofilm which protects itself from penetration of antibiotics, and therefore creates resistance towards antibiotics and difficult to eradicate. Objective: The aim of this study was to compare the sensitivity levels of chloramphenicol, polymyxin-neomycin, cyprofloxacin and ofloxacine against Pseudomonas aeruginosa in patients with active benign type CSOM in ENT clinic. Method: The method used was across sectional study on 25 patients, from August 2010 until December 2010. Samples were taken withear swab and then put on sensitivity test to chloramphenicol, polymyxin-neomycin, cyprofloxacin andofloxacine using the diffusion disc method. The analysis used in this study was Cochran test. Results: Results showed a significant difference in sensitivity among chloramphenicol (38,70%), polymyxinneomycin(83,87%),cyprofloxacin(90,32%)andofloxacin(58,06%)withp=0,000(p<0,05).PostHocanalysisusing the Mc Nemar indicated that there were significant differences in sensitivity betweenpolymyxin-neomycin to chloramphenicol with p=0,000 (p<0,05), ciprofloxacin to chloramphenicol andciprofloxacin to ofloxacine with p= 0,002, but there were no significant differences between cyprofloxacinto polymyxin-neomycin with p=0,687, polymyxin-neomycin to ofloxacin p=0.057 and ofloxacin tochloramphenicol p=0,109.   There were significant differences in antibiotic ear dropssensitivity to Pseudomonas aeruginosa in patients with active benign type of CSOM. Cyprofloxacin andpolymyxin-neomycin were more sensitive than ofloxacin and chloramphenicol. Keywords: Pseudomonas aeruginosa, active benign type of chronic suppurative otitis media, antibioticear drops.  Abstrak :  Latar belakang: Otitis media supuratif kronik (OMSK) merupakan penyakit infeksi kronik telinga tengah yang sering dijumpai di klinik THT. Penyebab tersering OMSK adalah bakteri Pseudomonasaeruginosa. Pseudomonas aeruginosa mempunyai kemampuan untuk membentuk biofilm yangmelindunginya dari penetrasi antibiotik sehingga menimbulkan resistensi terhadap antibiotik dan sulituntuk eradikasinya. Tujuan: Untuk mengetahui perbandingan tingkat sensitivitas kloramfenikol,polimiksin-neomisin, ciprofloksasin dan ofloksasin terhadap isolat Pseudomonas aeruginosa padapasien OMSK benigna aktif di klinik THT RSMS. Metode: Metode yang digunakan adalah crosssectional terhadap 29 pasien OMSK di klinik THT RSMS periode bulan Agustus 2010 - Desember2010. Pengambilan sampel dilakukan dengan swab telinga. Uji sensitivitas terhadap kloramfenikol,polimiksin-neomisin, ciprofloksasin dan ofloksasin dilakukan dengan metode cakram secara difusi.Analisis yang digunakan dalam penelitian ini adalah Cochran dan analisis post hoc. Hasil: Didapatkansensitivitas kloramfenikol sebesar 38,70%, polimiksin-neomisin sebesar 83,87%, ciprofloksasin sebesar90,32% dan ofloksasin sebesar 58,06% dengan p=0,01 (P<0,05), yang menunjukkan adanya perbedaansensitivitas yang bermakna antara kloramfenikol, polimiksin-neomisin, ciprofloksasin dan ofloksasinterhadap Pseudomonas aeruginosa. Analisis post hoc menggunakan Mc Nemar menunjukkan bahwaterdapat perbedaan sensitivitas yang bermakna antara tetes telinga polimiksin-neomisin terhadapkloramfenikol, dan ciprofloksasin terhadap kloramfenikol p=0,000 (p<0,05), serta terdapat perbedaanyang bermakna antara tetes telinga ciprofloksasin terhadap ofloksasin, p=0,002, tetapi tidak terdapatperbedaan yang bermakna antara ciprofloksasin terhadap polimiksin-neomisin, p=0,687, polimiksinneomisinterhadap ofloksasin p=0,057, dan kloramfenikol terhadap ofloksasin p=0,109. Kesimpulan:Terdapat perbedaan sensitivitas yang bermakna tetes telinga antibiotik terhadap Pseudomonas aeruginosa pada pasien OMSK benigna aktif. Ciprofloksasin dan polimiksin-neomisin tetes telinga mempunyai sensitivitas yang lebih baik dibanding ofloksasin dan kloramfenikol. Kata kunci: Pseudomonas aeruginosa, otitis media supuratif kronik, tetes telinga antibiotik 

Credit constraints and Rural Migration: Evidence from Six Villages in Uttar Pradesh

2018 ◽  
Vol 15 (3) ◽  
pp. 389-398
Author(s):  
Ruchi Singh
Keyword(s):  
Credit Constraints ◽  
Uttar Pradesh ◽  
Binary Logistic Regression ◽  
Binary Logistic Regression Model ◽  
Male Migration ◽  
Rural Economies ◽  
And Migration ◽  
The Relationship ◽  
The Empirical Analysis

Rural economies in developing countries are often characterized by credit constraints. Although few attempts have been made to understand the trends and patterns of male out-migration from Uttar Pradesh (UP), there is dearth of literature on the linkage between credit accessibility and male migration in rural Uttar Pradesh. The present study tries to fill this gap. The objective of this study is to assess the role of credit accessibility in determining rural male migration. A primary survey of 370 households was conducted in six villages of Jaunpur district in Uttar Pradesh. Simple statistical tools and a binary logistic regression model were used for analyzing the data. The result of the empirical analysis shows that various sources of credit and accessibility to them play a very important role in male migration in rural Uttar Pradesh. The study also found that the relationship between credit constraints and migration varies across various social groups in UP.

scholarly journals The relationship between the expression of PLIN3 and PLIN5 protein flowing endurance training in streptozotocin rats

2019 ◽  
Vol 21 (4) ◽  
pp. 194-199
Author(s):  
Mahdi Ghafari ◽  
Ebrahim Banitalebi ◽  
Mohamad Faramarzi
Keyword(s):  
Insulin Resistance ◽  
Endurance Training ◽  
High Intensity ◽  
Training Group ◽  
Control Group ◽  
High Intensity Training ◽  
Significant Difference ◽  
Post Hoc ◽  
The Relationship ◽  
Intensity Training

Background and aims: Intermuscular lipolysis disorder plays an important role in insulin resistance and diabetes mellitus and perilipin PLIN5 and PLIN3 are the key proteins in regulating muscle cellular lipolysis. Therefore, the purpose of this study was to examine the relationship between the expression of PLIN3 and PLIN5 protein following endurance training in streptozotocin (STZ) rats. Methods: A number of 24 male Wistar rats were randomly divided into low endurance training group (n = 8), high-intensity training group (n = 8), and control group (n = 8). Diabetes was induced in every rat by STZ injection. Three days after injection, the blood samples were taken from the cut tip of the tails of the mice and animals with blood glucose greater than 300 mg/dL were considered diabetic. The training program included eight weeks of aerobic training at different intensities. Training in high- and low-intensity groups included 22-25 and 5-8 m/min of training. Finally, one-way analysis of variance (ANOVA) and correlation was used to determine the significance of the differences between variables, followed by utilizing Tukey’s post-hoc test for significance. Results: The comparison between the groups by ANOVA showed significant differences in PLIN3 (P=0.0006) and PLIN5 (P=0.012). The results of Tukey post hoc test also demonstrated a statistical difference between the mean values of diabetic control group and high-intensity endurance group regarding PLIN3 (P=0.01) and PLIN5 (P=0.009), but no significant increase was observed in the lowintensity exercise group as compared to the control group (PLIN3, P=0.067 & PLIN5, P=0.44). As regards insulin resistance, there was a significant difference among the three groups (P=0.0001). Eventually, the result of the correlation between PLIN3 and PLIN5 showed similar enhancement by increasing the intensity (P=0.0026). Conclusion: According to research results, high-intensity endurance training increased the expression of PLIN3 and PLIN5 in diabetic specimens and PLIN3 and PLIN5 followed a similar increase pattern in high-intensity training

scholarly journals Personality Correlates of Optimism among Couples

2016 ◽  
Vol 3 (4) ◽  
Author(s):  
Naseem Ahmad ◽  
Azmat Jahan ◽  
Nasheed Imtiaz
Keyword(s):  
Personality Traits ◽  
Intervention Programs ◽  
Test Results ◽  
Life Orientation Test ◽  
Life Orientation ◽  
Eysenck Personality Inventory ◽  
Personality Correlates ◽  
Significant Difference ◽  
The Relationship ◽  
Orientation Test

This study aimed to examine the relationship between optimism and personality traits (extraversion-introversion, emotional stability-neuroticism and psychoticism) among couples. The study sample consisted of 30 couples, N=60 (30 males and 30 females) with age ranging from 22 to 28 years were selected from the various places of Delhi NCR. For assessing personality traits, Eysenck Personality Inventory-Revised (EPI-R) by Hans Eysenck was employed and for assessing optimism, Life Orientation Test-Revised (LOT-R) developed by Scheier, Carver, and Bridges (1994) was used. Results of the present study were analysed using Pearson-r correlation and t test. Results of study revealed that:  there is a significant positive correlation between optimism and extraversion (personality traits), (r=.368) and no significant correlation between any other constructs of personality and optimism.  Also, there is no significant difference found between male and female on any of the personality traits (extraversion, (t=.912); neuroticism, (t=-.134); and psychoticism, (t=-.423).) and optimism, (t=1.548). The study has important implications for intervention programs.

scholarly journals The Relationship between Non-audit Services and Auditor Independence: Evidence from Chinese Listed Companies

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Xiaobo Hao
Keyword(s):  
Rapid Development ◽  
Binary Logistic Regression ◽  
Listed Companies ◽  
Auditor Independence ◽  
Binary Logistic Regression Model ◽  
Western Countries ◽  
Chinese Listed Companies ◽  
Independent Variable ◽  
The Relationship ◽  
Non Audit Services

The rapid development of non-audit services (NAS) has jeopardized the independence of auditors, which has led many Western countries to enact regulations that restrict the provision of NAS. While in China, NAS have just emerged, and its development in China is far less mature than in Western countries. The purpose of this paper is to explore whether NAS in China have damaged auditor independence and whether Chinese regulators need to emulate Western countries and strongly limit the provision of NAS. In order to achieve this objective, 213 Chinese listed companies are selected in this study. The audit opinions issued by the auditors are used as substitute variables for auditor independence (dependent variables), and the ratio of non-audit service fees to the total of audit service fees and non-audit service fees as a substitute variable for the provision of NAS (independent variable), and meanwhile some suitable control variables are also selected. Analyse these data by building a binary logistic regression model. The results show that there is no evidence in China that NAS can undermine auditor independence and there is no need for China to enact regulations to prohibit the provision of NAS.

scholarly journals Do cigarette and alcohol affect semen analysis?

2016 ◽  
Vol 88 (1) ◽  
pp. 56 ◽  
Author(s):  
Mehmet Zeynel Keskin ◽  
Salih Budak ◽  
Saim Gubari ◽  
Kalender Durmaz ◽  
Mehmet Yoldas ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Semen Analysis ◽  
Threshold Value ◽  
Semen Parameters ◽  
Control Group ◽  
Cigarette Use ◽  
Group 4 ◽  
Semen Volume ◽  
Significant Difference ◽  
The Relationship

Objectives: There are a number of studies about the effect of cigarette and alcohol on semen parameters in the literature. There is not a consensus on the relationship between use of cigarette and alchol and semen parameters in those studies. The number of studies in which cigarette and alcohol use are evaluated together is limited. This study was aimed to analyze the effect of cigarette and/or alcohol use on semen parameters. Methods: In this prospective study, 762 patients who applied to an hospital urology polyclinic between January 2015 and March 2015 due to infertility, were questioned for alcohol and cigarette use in anamnesis. The remaining 356 patients were included in our study. Then, semen analysis of the patients was performed. The patients were divided into five groups according to cigarette use, into five groups according to alcohol use and into four groups according to cigarette and/or alcohol use. Significant differences were analyzed between the groups in terms of semen volume, semen concentration, total motility, forward motility and morphological (normality, head anomaly, neck anomaly, tail anomaly) values. Results: According to cigarette use, only in group 4 (who use more than 20 package-years cigarette) semen volume was significantly lower than the control group (Mann-Whitney U, p = 0.009). There was no significant difference in any of the other parameters and groups compared with the control group (Mann-Whitney U, p &gt; 0,05) Conclusion:According to our study, using more than 20 package- years cigarette decreases semen volume. The reason of this result might be the fact that the threshold value, from which the effect of cigarette and alcohol use on the semen parameters has to be determined.

scholarly journals Influence of maxillary canine torque variations on the perception of smile esthetics among orthodontists and laypersons

2019 ◽  
Vol 24 (1) ◽  
pp. 53-61 ◽  
Author(s):  
Thiago Correia Barbosa Lemos ◽  
Juliana de Brito Vasconcelos ◽  
Bianca Mota dos Santos ◽  
Andre Wilson Machado
Keyword(s):  
Analysis Of Variance ◽  
T Test ◽  
Test Results ◽  
Maxillary Canine ◽  
Visual Analog Scales ◽  
Significant Difference ◽  
Unpaired Student ◽  
Full Face ◽  
Smile Esthetics ◽  
Post Hoc

ABSTRACT Objective: The purpose of this study was to determine the perception of smile esthetics among orthodontists and laypersons with respect to unilateral maxillary canine torque variations in a frontal smile analysis. Methods: Full face and close-up smile photographs of two subjects (1 man and 1 woman) were used. Both smiles displayed healthy maxillary anterior dentitions. The images were digitally altered to obtain a bilateral 0° torque in the maxillary canines. From this image, unilateral variations of the left canine were made with -15°, -10°, -5°, 0°, +5°, +10° and +15°. Final images were randomly assembled into an album that was given to 53 orthodontists and 53 laypersons. Each rater was asked to evaluate the attractiveness of the images using visual analog scales. Data collected were statistically analyzed with one-way analysis of variance with Tukey post-hoc test and the unpaired Student t test. Results: For orthodontists, most attractive smiles were those with 0°, -5° and -10°. For laypersons, most attractive smiles were those with 0°, -5°, -10°, -15° and + 5°. For both groups, the lowest scores were given for the smiles with +10° and +15° torque. When comparing the perceptions of the orthodontists and laypersons, they did not show statistical differences in most situations. Moreover, in general, there was no significant difference between the full-face and close-up assessments of the smiles. Conclusions: The present findings indicated that smiles with unilateral palatal (negative values) maxillary canine torque variations were more tolerated than smiles with buccal crown torque (positive values) variations.

Validation of Several Methods of Estimating Maximal Oxygen Uptake in Young Men

1998 ◽  
Vol 87 (2) ◽  
pp. 575-584 ◽  
Author(s):  
Lars McNaughton ◽  
Phil Hall ◽  
Dean Cooley
Keyword(s):  
Young Men ◽  
Gas Analysis ◽  
Accurate Predictor ◽  
Post Hoc Analysis ◽  
Significant Difference ◽  
Run Test ◽  
Post Hoc ◽  
The Relationship ◽  
Treadmill Protocol ◽  
Shuttle Run

The purpose of this study was to identify the most accurate predictor of VO2max from a variety of running tests. 32 young adult male undergraduates of (mean ± SE) age 20.14 ± 0.34 yr., height 179.4 ± 1.8 cm, weight 73.7±2.8 kg, and VO2max 57.89 ± 1.1 ml · kg−1 · min.−1 were randomly tested on four different predictive VO2max running tests to assess their actual VO2max, based on a continuous, progressive treadmill protocol and obtained via gas analysis. The four tests consisted of a treadmill jogging test, 1.5 mile run, Cooper's 12-min. run, and the 20-m progressive shuttle-run test. An analysis of variance applied to means indicated significance. Post hoc analysis between the means with correction by Scheffé showed significant difference between the predictive submaximal treadmill jogging test and the 12-min. run but no other difieren .es. The strength of the relationship between predictive tests and VO2max varied, wit1 the 12-min run having the highest correlation of .87, followed by the 1.5 mile rur .87, 20-m progressive shuttle run .82, and the treadmill jogging test .50. The 12-min. run had the highest correlation of all tests with VO2max in young men, with active to trained levels of fitness. The 1.5 mile and 20-m shuttle run also provided accurate predictions of VO2max and so should be used for an accurate prediction of young men's VO2max.

Vibration Transmissibility on Foot during Controlling and Operating Car Accelerator Pedal

2013 ◽  
Vol 471 ◽  
pp. 151-155
Author(s):  
A.R. Yusoff ◽  
Baba M. Deros ◽  
D.D.I Daruis
Keyword(s):  
Lower Extremity ◽  
Medium Size ◽  
Accelerator Pedal ◽  
Vehicle Engine ◽  
Large Size ◽  
Honestly Significant Difference ◽  
Significant Difference ◽  
Vibration Transmissibility ◽  
Post Hoc ◽  
The Relationship

The purpose of this paper is to discuss the vibration transmissibility from a cars body to pedal-pad, and the lower extremity, especially on the foot. The vibration transmissibility will occur when the foot interacts with the pedal-pad once the vehicle engine is turned on. The vibrations transmissibility will cause drivers discomfort, especially on the lower extremity due to fatigue and tiredness of the foot. The relationship between vibration transmissibility with the different sizes pedal-pad to the foot, and whether it can contribute to the foot discomfort during handling and controlling pedal-pad while driving is investigated. The variables are the different sizes of pedal-pad. Data was recorded from foot on three different sizes of pedal-pads. The data was measured in root mean square (r.m.s) unit, of the frequency weighted acceleration (m/s2) for every minute. The result for the foot-transmitted-vibration shows the ratio value of medium sized pedal-pad is greater than 1; compared to small sized and large sized pedal-pads which is less than 1. Analysis of One-way Anova shows that the mean of different sizes of pedal-pad is significant. Tukeyspost-hocwith HSD (Honestly Significant Difference) test on the foot transmitted-vibration proves that the means for medium size pedal-pad is the highest compared with the small and large size pedal-pads.

Proactive Versus Reactive Perpetrators: Aggression and Intimate Partner Violence

Partner Abuse ◽  
2018 ◽  
Vol 9 (2) ◽  
pp. 103-117
Author(s):  
Hyun-Soo Lee ◽  
Arthur Cantos ◽  
Jami Mach ◽  
Jennifer Wolff
Keyword(s):  
Intimate Partner Violence ◽  
Partner Violence ◽  
Reactive Aggression ◽  
Binary Logistic Regression ◽  
Intimate Partner ◽  
Proactive Aggression ◽  
Recidivism Rates ◽  
Significant Difference ◽  
Chi Square Analysis ◽  
The Relationship

The relationship between proactive and reactive aggression could have significant implications for the conceptualization of intimate partner violence. In this study, victim statements found in police reports involving 299 unique adult male perpetrators were coded for proactive or reactive aggression content and analyzed in relation to existing measures of treatment outcomes. Family-only violent perpetrators were hypothesized to be rated as having used reactive aggression, and generally violent perpetrators were expected to have used proactive aggression. It was further predicted that proactive aggression would be more strongly associated with higher recidivism rates and lower intervention completion rates. Perpetrators were coded as 73.8% reactive and 26.2% proactive contrary to the assumptions of some sociocultural models of intimate partner violence, for example, the Duluth model. Chi square analysis was used to assess the relationship between type of aggression and typology. Reactive perpetrators who completed their intervention had significantly lower recidivism rates than reactive perpetrators who did not. Intervention completion was unrelated to recidivism rates for proactive perpetrators. In fact, no statistically significant difference was found between type of aggression and recidivism when controlling for intervention completion. Binary logistic regression was used to assess the relationship between type of aggression used, intervention completion, and recidivism with no significant associations found. These findings further clarify the relevance of reactive aggression in intimate partner violence perpetrators due to its relative frequency and potential intervention effects.

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