scholarly journals UJI EFEKTIVITAS AIR PERASAN JERUK NIPIS (Citrus aurantifolia (Christm.) Swingle)DALAM MENGHAMBAT PERTUMBUHAN JAMUR Candida albicans

2021 ◽  
Vol 3 (2) ◽  
pp. 96-101
Author(s):  
Toto Santoso ◽  
Sukmawati Sukmawati ◽  
Alda Miranti
Keyword(s):  
Candida Albicans ◽  
Citrus Aurantifolia ◽  
Sabouraud Agar

Masalah yang sering terjadi di masyarakat adalah penyakit kandidiasis yang disebabkan oleh beberapa jamur salah satunya Candida albicans. Jeruk nipis (Citrus aurantifolia (Christm.) Swingle) merupakan tanaman obat yang tumbuh subur di negara Indonesia. Salah satu kandungan utama dari jeruk nipis (Citrus aurantifolia (Christm.) Swingle) adalah flavonoid yang memberikan berbagai macam aktivitas farmakologi sebagai antifungi, antibakteri dan antikanker. Penelitian ini bertujuan untuk mengetahui efektivitas air perasan jeruk nipis, (Citrus aurantifolia (Christm.) Swingle) dalam menghambat pertumbuhan jamur Candida albicans. Metode yang digunakan dalam penelitian ini adalah dengan cara dilusi padat yaitu dengan cara menanam biakan  suspensi jamur Candida albican  sebanyak 1 ml yang telah di sesuaikan kekeruhannya dengan larutan standar Mc Farland 0.5 pada media SDA (Sabouraud Agar Dexrose) dengan penambahan air perasan jeruk nipis sebanyak 2 ml dengan konsentrasi 125%, 150%, 175% dan 200%. Di inkubasi selama 2-3 hari pada 370C, dan diamati pertumbuhannya. Hasil dari pengamatan selama tiga hari menunjukan bahwa air perasan jeruk  nipis tidak efektif dalam menghambat pertumbuhan jamur Candida albicans, meskipun pada konsentrasi 175% dan 200% pertumbuhan jamur pada hari pertama sangat sedikit, tetapi pada hari kedua dan ketiga masih ada perluasan pertumbuhan jamur Candida albicans.

scholarly journals Evaluación de la diversidad de bacterias lácticas y levaduras en quesos frescos de cabra de la quebrada de Humahuaca

2015 ◽  
Vol 13 (1) ◽  
pp. 03
Author(s):  
E Gustavo Ancasi ◽  
S Maldonado ◽  
R Oliszewski
Keyword(s):  
Candida Albicans ◽  
Kluyveromyces Lactis ◽  
Debaryomyces Hansenii ◽  
Pichia Anomala ◽  
Dekkera Bruxellensis ◽  
Sabouraud Agar ◽  
Zygosaccharomyces Rouxii ◽  
Candida Magnoliae ◽  
Candida Versatilis

Los quesos frescos de cabra artesanales de la quebrada de Humahuaca son elaborados con leche cruda, cuya maduración genera sabores, aromas y texturas característicos de la región. Los objetivos de este estudio fueron identificar y caracterizar bacterias lácticas (BAL) y levaduras nativas, aisladas de quesos frescos de esta zona productora. De un total de 36 muestras sembradas en agar Sabouraud, agar MRS y M17, se obtuvieron 128 levaduras y 39 lactobacilos, los que fueron identificados fenotípicamente y evaluadas las siguientes propiedades tecnológicas: pH a la coagulación, tasa de acidificación, proteólisis en agar leche, lipólisis en agar triacetina, producción de acetoína en leche reconstituida y asimilación del citrato en agar citrato. Lb. delbruekii subsp. bulgaricus, Lb. casei subsp. pseudoplantarum, Lb. plantarum var. arabinosus, Lb. plantarum var. plantarum, Lb. casei subsp. rhamnosus, Lb. acidophilus, Lb. helveticus, Lb. fermentum, Lb. brevis var. brevis, Lactococos sp. y Enterococcus sp. fueron las bacterias lácticas identificadas. Del total de los aislamientos, 41,6% coagularon la leche en 10 horas y 33% en 5 horas. Lb. helveticus coaguló la leche a pH de 5,40 en 5 horas, hasta alcanzar un valor final de 4,16 en 24 h, mientras que Lb. delbrueckii subsp. bulgaricus y Lb. fermentum iniciaron la coagulación en 5 horas, con valores de pH iniciales de 4,81 y 4,92 hasta valores finales de 4,19 y 4,21 respectivamente. Lb. helveticus, Lb. delbrueckii subsp. bulgaricus, Lb. plantarum var. arabinosus, Lb. fermentum, Lb. casei subsp. rhamnsosus, Lb. casei subsp. pseudoplantarum, Lb. brevis var. brevis, en orden descendente, demostraron tener capacidad acidificante. Lb. fermentum y Lb. casei subsp. pseudoplantarum desarrollaron actividad proteolítica y sólo Lb. plantarum var. plantarum demostró tener actividad lipolítica. Las levaduras aisladas fueron Debaryomyces hansenii, Zygosaccharomyces rouxii, Kluyveromyces lactis, Wickerbamiela domerquiae, Dekkera bruxellensis, Candida valdiviana, Candida novakii, Dekkera bruxellensis, Candida versatilis, Candida magnoliae, Candida albicans, Pichia anómala, Dekkera anómala y Rodotorula sp. Cepas de D. hansenii, C. magnoliae, Z. rouxii,C. versatilis y K. lactis tuvieron actividad proteolítica y lipólitica, y una cepa de W. domerquiae tuvo solamente actividad proteolítica. Algunas cepas de K. lactis produjeron acetoína y D. bruxellensis y C. versatilis metabolizaron el citrato, hidrolizaron la caseína y tuvieron actividad lipolítica.  Los resultados obtenidos en este estudio muestran que la composición de las poblaciones de BAL y levadura en quesos artesanales es específica de la región. Los conocimientos adquiridos en este estudio podrían ser utilizados para la obtención de cultivos iniciadores con cepas de BAL y levaduras específicas de la región, destinados a la producción de quesos frescos con origen geográfico específico.

scholarly journals Cross-Contamination Risk of Dental Tray Adhesives: An In Vitro Study

Materials ◽  
2021 ◽  
Vol 14 (20) ◽  
pp. 6138
Author(s):  
Isabel Paczkowski ◽  
Catalina S. Stingu ◽  
Sebastian Hahnel ◽  
Angelika Rauch ◽  
Oliver Schierz
Keyword(s):  
Staphylococcus Aureus ◽  
Candida Albicans ◽  
Artificial Saliva ◽  
In Vitro Study ◽  
Cross Contamination ◽  
Sabouraud Agar ◽  
Liquid Samples ◽  
Streptococcus Oralis ◽  
Colony Forming Units

Background: The aim of this study was to investigate the risk of cross-contamination in dental tray adhesives with reusable brush systems. Methods: Four dental tray adhesives with different disinfectant components were examined for risk as a potential transmission medium for Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Streptococcus oralis, and Candida albicans. Bacterial and fungal strains were mixed with artificial saliva. The contaminated saliva was intentionally added to tray adhesive liquid samples. At baseline and up to 60 min, 100 microliters of each sample were collected and cultivated aerobically on Columbia and Sabouraud agar for 24 or 48 h, respectively. Results: At baseline, contamination with Staphylococcus aureus and Candida albicans could be identified in three out of four adhesives. In the subsequent samples, low counts of up to 20 colony-forming units per milliliter could be observed for Staphylococcus aureus. All other strains did not form colonies at baseline or subsequently. Adhesives with isopropanol or ethyl acetate as disinfectant additives were most effective in preventing contamination, while adhesives with hydrogen chloride or acetone as a disinfectant additive were the least effective. Conclusion: Within 15 min, the tested adhesives appeared to be sufficiently bactericidal and fungicidal against all microorganisms tested.

scholarly journals Antifungal susceptibility of Candida albicans isolated from oral mucosa of patients with cancer

1999 ◽  
Vol 13 (3) ◽  
pp. 219-223 ◽  
Author(s):  
Lino João da COSTA ◽  
Esther Goldenberg BIRMAN ◽  
Sidney Hartz ALVES ◽  
Arlete Emily CURY
Keyword(s):  
Candida Albicans ◽  
Cancer Patients ◽  
Amphotericin B ◽  
Oral Mucosa ◽  
Antifungal Susceptibility ◽  
New Drugs ◽  
Local Conditions ◽  
Opportunistic Fungi ◽  
Sabouraud Agar

The increasing number of oral infections due to opportunistic fungi in immunocompromised patients, needs a new evaluation of the drugs in use. The susceptibility in vitro of Candida albicans strains from the oral mucosa of cancer patients to amphotericin B, ketoconazole, miconazole, fluconazole and itraconazole were evaluated. A dilution technique in YNB agar or subculture on Sabouraud agar was utilised for MIC or MFC determinations. With this methodology, the best fungicidal drug for C.albicans collected from the oral mucosa of 40 cancer patients, divided in two groups: one treated by radiotherapy and the other not, the best results were obtained with amphotericin B, presenting low values of MIC compared to azoles and MFC values. However it is important to take into consideration the utilisation in vivo of this polyenic antibiotic and the possible toxic levels necessary to achieve good results. The coexistence of other fungi and the local conditions must also be pondered with these patients, who are mostly undergoing radiotherapy. In order to achieve better results without undesirable consequences, higher levels of MIC are expected with the daily clinical use of new drugs.

scholarly journals The Effectiveness of PCR in Diagnosis of Fungal Keratitis

2020 ◽  
Vol 17 (4) ◽  
pp. 824-829
Author(s):  
G. I. Krichevskaya ◽  
L. A. Kovaleva ◽  
I. D. Zyurnyayeva ◽  
P. V. Makarov ◽  
A. E. Andryushin
Keyword(s):  
Candida Albicans ◽  
Rapid Determination ◽  
Pathogenic Fungi ◽  
Fungal Keratitis ◽  
Diagnostic Methods ◽  
Pcr Analysis ◽  
Differential Detection ◽  
Visual Disability ◽  
Sabouraud Agar ◽  
Microbiological Methods

Fungi implicated in mycotic keratitis include different species. Conventional methods for the diagnosis of fungal keratitis include staining of corneal scarpings, culture medium (Sabouraud agar) for isolating fungi.Purpose. To evaluate the effectiveness of polymerase chain reaction (PCR) for the detection of fungal etiology in comparison with the conventional diagnostic methods in cases with suspected fungal corneal ulcer.Patients and methods. Seven patients with severe corneal ulcers with more than 3 weeks duration. Corneal scarpings and corneal buttons from seven patients who had undergone therapeutic keratoplasty were used for microbiological and PCR analysis. PCR diagnostic kits for the differential detection of Candida albicans DNA and total fungi DNA (DNA Fungi), which allows to identify most pathogenic fungi without determining their species were used. Microbiological methods: microscopy of gramstained smears, culture techniques, including selective for fungi agar Saburo with chloramphenicol.Results. PCR: Fragments of all corneas removed from keratoplasty (6 patients) revealed fungal-common DNA (Fungi DNA) and did not detect Candida albicans DNA, which correlated with sowing results on Saburo medium (mold fungi found in 5 of 6 corneas). Fungi DNA was also detected in the corneal scraps taken prior to surgery; however, growth of fungi during sowing on various nutrient media was not found.Conclusion. Corneal fungal ulcers are a serious disease, often leading to visual disability. The rapid determination of etiology and the correct choice of therapy determines the outcomes of the disease. The advantage of PCR over the culture method: the speed of obtaining results (4 hours instead of 3–7 days); high sensitivity, which allows detecting fungi not only in the tissue of the removed cornea, but also in scrapes from the cornea ulcer of patients who previously received antifungal therapy. The presence of commercial kits for differential detection of fungal-common DNA and DNA of Candida albicans extends the possibilities of PCR in the screening diagnosis of fungal keratitis and the selection of drugs before determining the type of pathogen. 

scholarly journals Can the Diagnosis of Recurrent Vulvovaginal Candidosis Be Improved by Use of Vaginal Lavage Samples and Cultures on Chromogenic Agar?

2002 ◽  
Vol 10 (2) ◽  
pp. 89-92 ◽  
Author(s):  
N. Novikova ◽  
A. Rodrigues ◽  
P.-A. Mårdh
Keyword(s):  
Candida Albicans ◽  
Recovery Rate ◽  
Detection Rate ◽  
Rapid Identification ◽  
Biochemical Tests ◽  
Vaginal Lavage ◽  
Yeast Infection ◽  
Sabouraud Agar ◽  
Chromogenic Agar ◽  
Vulvovaginal Candidosis

Objective:To investigate if introital and vaginal flushing samples inoculated on chromogenic agar could increase the recovery rate and rapid identification ofCandidaand non-albicansspecies, as compared to culture of posterior vaginal fornix samples on Sabouraud agar and speciation of isolates by biochemical tests.Methods:Samples from the introitus and the posterior vaginal fornix and vaginal lavage samples were collected from 91 women with a history suggestive of recurrent vulvovaginal candidosis (RVVC), and with a suspected new attack of the condition. The specimens were cultured on Sabouraud and CHROMagar®. Speciation of yeast isolates was made on the chromogenic agar by API 32C®kits and by an atomized system (Vitek®).Results:Forty-six (51%) women were positive forCandidafromone or more of the samples. The introital cultures were positive in 43 (47%) women, both on Sabouraud and chromogenic agar. From the posterior vaginal fomix, 42 (46%) women were positive on the Sabouraud and 43 (47%) on chromogenic agar cultures, while the vaginal lavage cultures yieldedCandidaon those two media in 40 (44%) and 4l (45%) cases, respectively.Candida albicanswas the most frequent species recovered, from 40 (87%) cases, followed byC. kruseiin 4 (9%),C. glabratain 2 (4%), andC. parapsilosisin one case. There was only onewoman who had a mixed yeast infection, byC. albicansandC. krusei. There was only one discrepancy in the speciation as demonstrated by mean of chromogenic agar and API 32C kit.Conclusions:Neither cultures of introital nor of vaginal lavage samples increases the detection rate ofCandidain RVVC cases as compared to cultures of posterior vaginal fornix samples. Use of chromogenic agar is a convenient and reliable means to detect colonization byCandidaand differentiate betweenC. albicansand non-albicansspecies.

scholarly journals IN VITRO ANTIFUNGAL ACTIVITY OF TIMOL AND CARVACROL ON CANDIDA SPECIES

2019 ◽  
Vol 4 ◽  
Author(s):  
Luciana Thaís Rangel Souza ◽  
Cecília Correia Costa ◽  
Mateus Cardoso Oliveira ◽  
Isabel Celeste Caires Pereira Gusmão
Keyword(s):  
Candida Albicans ◽  
Antifungal Activity ◽  
Inhibitory Concentration ◽  
Candida Krusei ◽  
Minimum Fungicidal Concentration ◽  
Sabouraud Agar ◽  
In Vitro Antifungal Activity

Aim: to evaluate the in vitro action of thymol and carvacrol against the yeasts of Candida albicans ATCC10231 and Candida krusei ATCC34135. Method: A laboratory study was performed to evaluate antifungal activity. The characterization of the Minimal Inhibitory Concentration (MIC) of the thymol essential oil was carried out using the technique where the microdilution is performed, in which a plate containing 96 wells is used. The determination of the Minimum Fungicidal Concentration (MFC) was performed by dripping 10 μL of each of the concentrations evaluated on Sabouraud agar plates. Results: The MIC of thymol and carvacrol for C. albicans was 40 μg/mL and for Candida krusei it did not present antifungal activity. While the MIC of nystatin was 0.03mg for both species with thymol and carvacrol. Conclusion: Thymol presented satisfactory antifungal activity against the pathogens studied, but carvacrol did not present antifungal activity.

scholarly journals Potentials of Betel Leaf Infusion (Piper betle L), Lime Peel Extract (Citrus aurantifolia) and Bundung Extract (Actinoscirpus grossus) as Candidiasis Therapy

2020 ◽  
Vol 16 (2) ◽  
pp. 95
Author(s):  
Darini Kurniawati ◽  
Kunti Nastiti
Keyword(s):  
Candida Albicans ◽  
Inhibitory Activity ◽  
Antimicrobial Properties ◽  
Piper Betle ◽  
Citrus Aurantifolia ◽  
Hand Sanitizer ◽  
Betel Leaf ◽  
Agar Media ◽  
Lime Peel ◽  
Peel Extract

Abstract: Candidiasis is an infection caused by the fungus Candida, especially Candida albicans. It often occurs in the mouth and sex organs, also in the nails, respiratory tract, digestive tract, and anus. Betel leaf stew is often used by people to gargle and clean the intimate organs. The nature of the betel leaf solution is easily oxidized and turns brown. Therefore, research needs to be done by mixing betel leaf (Piper betle L) with lime (Citrus aurantifolia) to maintain the color of betel leaf, coupled with natural ingredients that have antimicrobial properties, namely lime peel and bundung plants (Actinoscirpus grossus). With the hypothesis of the joining of three natural materials that have antimicrobial activity can strengthen the inhibitory activity of the fungus Candida albicans. This research was conducted by making a betel leaf infusion formulation, lime peel extract, and bundung extract with a concentration of 20%, 30%, 40%, and 50% which were then tested to determine the effect of the infusion formulation on the inhibitory activity of Candida albicans by the method spread on Saburoud Dextrose Agar media. Based on Zuraidah's research (2015), 80% and 100% betel leaf extraction has activity on Candida albicans. From the results of this study significant results were obtained at a concentration of 50% of a mixture of betel leaf infusion formulations, extracts of lime peel and bundung extract had the same inhibitory properties as the hand sanitizer antiseptic liquid against Candida albicans. Thus it can be concluded that the 50% test formulation of betel leaf infusion mixture with lime extract and bundung extract has greater potential than betel leaf extract alone as a candidiasis therapy. Keywords: Piper betle L, Citruss aurantifolia, Actinoscirpus grossus, Antiseptik, Kandidiasis, Candida albicans

scholarly journals UJI EFEKTIVITAS AIR PERASAN JERUK NIPIS (CITRUS AURANTIFOLIA) DAN AIR JERUK LEMON (CITRUS LIMON) DALAM MENGHAMBAT PERTUMBUHAN JAMUR CANDIDA ALBICANS

2020 ◽  
Vol 5 (4) ◽  
Author(s):  
Windy Claudia Lubis ◽  
Elisabet Tampubolon ◽  
Ali Napiah Nasution ◽  
Riyani Susan Bt Hasan
Keyword(s):  
Candida Albicans ◽  
Citrus Limon ◽  
Citrus Aurantifolia

Mayoritas masyarakat Indonesia menggunakan bahan-bahan alami untuk melakukan pengobatan, sepertijeruk nipis dan jeruk lemon dikarenakan mudah ditemukan. Masyarakat biasa menggunakannya untukmeredakan batuk,influenza,sakit tenggorokan, menurunkan demam,hingga kandidiasis atau biasa diketahuisariawan. Kandidiasis adalah suatu infeksi yang ada pada kulit maupun juga pada selaput lendir dimanadisebabkan akibat jamur dari jenis candida tetapi paling sering disebabkan oleh candida albicans. Penelitianyang dilakukan menggunakan desain eksperimental memakai metode dari difusi cakram. Berlandaskan datadari pengujian sudah dilakukan menyatakan adanya pengaruh pada air perasan jeruk nipis padaperkembangan jamur Candida Albicans dari konsentrasi 25% (10,26 mm),50% (14,53 mm),75% (16,96mm),dan 100% (18.06 mm). Dari semua konsentrasi air perasan jeruk nipis yang telah di uji,konsentrasi100%(18,06 mm) memiliki daya hambat yang paling tinggi dan konsentrasi 25%(10,26mm) merupakan dayahambat minimum terhadap pertumbuhan candida albicans. Untuk hasil pengujian air perasan jeruk lemonmenunujukkan bahwa terhadap pengaruh air perasan jeruk lemon terhadap pertumbuhann jamur CandidaAlbicans dari konsentrasi 25% (12,83 mm),50% (15,1 mm),75% (16,7 mm),dan 100% (19.36). Dari semuakonsentrasi air perasan jeruk lemon yang telah di uji , konsentrasi 100% (19,36) memiliki daya hambat yangpaling tinggi dan konsentrasi 25%(12,83mm) merupakan daya hambat minimum terhadap pertumbuhancandida albicans. Untuk kontrol positif menggunakan ketoconazole 2%(22,16mm) dimana memiliki efek yanglebih tinggi untuk menghambat perkembangan jamur candida albicans. Berlandaskan dari penelitian sudahdilakukan bisa ditarik kesimpulan bahwa adanya efek dalam menurunkan pertumbuhan dari air perasan jeruknipis juga jeruk lemon untuk pertumbuhan Candida Albicans.Kata kunci : Perasan jeruk nipis dan lemon , candida albicans , Kandidiasis 

scholarly journals Prevalence of Candida albicans among Female Patients in Two Selected Hospitals in Owerri Metropolis, Imo State Southeastern Nigeria

2020 ◽  
pp. 1-8
Author(s):  
M. O. Nwachukwu ◽  
J. N. Azorji ◽  
P. C. Onyebuagu ◽  
L. A. Adjeroh ◽  
S. N. Nmezi
Keyword(s):  
Public Health ◽  
Risk Factors ◽  
Candida Albicans ◽  
Structured Interview ◽  
Female Reproductive Tract ◽  
Biochemical Tests ◽  
Southeastern Nigeria ◽  
Sabouraud Agar ◽  
Female Patients ◽  
Tract Infections

The incidence of candidiasis in the female reproductive tract is a serious threat to public health. This study assesses the prevalence of Candida albicans among female patients in the two selected hospitals in Owerri metropolis. A systematic random sampling technique was used to select 120 female patients between the ages of 16-56 years. Only patients who showed no symptoms of urinary tract infections and who were not on anti-fungal therapy at the time of the study were included in the study. A well-structured interview questionnaire was used to source information on socio-demographic characteristics of the respondents as well as the risk factors of Candida albicans infections. High Vaginal Swab (HVS) was aseptically collected from each of the patients, using a sterile swab stick. The collected samples were labeled appropriately and immediately sent to the microbiology/mycology lab for analysis. The HVS samples were respectively streaked directly into sabouraud agar plates and incubated anaerobically at 37oC for 48 hours. Yeast growth characteristics were noted. Positive colonies were sub-cultured in Macconkey agar to obtain pure isolates. The Candida albicans were properly identified and confirmed by germ tube test, gram staining and biochemical tests. The results showed that the overall prevalence of Candida albicans among the women was (53.34%). The prevalence was highest among the patients in the age group 16-25 (44.17%), lower education qualification (n=65, 54.17%) and pregnant women (n=44, 36.67%). The possible risk factors for the infection include use of antibiotics (n=85, 70.83%), use of nylon underwear (n=78, 65.00), use of public toilet (n=90, 75.00%), use of squat WC (n=59, 9.17%) and use of oral contraceptive (n=59, 49.17%). The results call for preventive measures to protect women. Therefore public health education and campaign should be adopted.

scholarly journals Original Research. Candida in Oral and Maxillofacial Pathology: Clinical Findings and Risk Factors

2017 ◽  
Vol 2 (s1) ◽  
pp. 36-42 ◽  
Author(s):  
Cecilia Petrovan ◽  
Despina Luciana Bereczki-Temistocle ◽  
Adrian Man
Keyword(s):  
Risk Factors ◽  
Candida Albicans ◽  
Oral Cavity ◽  
Oral Pathology ◽  
Predisposing Factors ◽  
Original Research ◽  
Candida Colonization ◽  
Contributing Factors ◽  
Sterile Saline ◽  
Sabouraud Agar

AbstractBackground: Candida, and especially Candida albicans, colonizes the oral mucosa and becomes invasive when the immune system weakens. Therefore, frequently, oral and maxillofacial pathology can be associated with Candida. Objective: The qualitative and quantitative assessment of Candida colonization of the oral cavity in patients with oro-maxillo-facial conditions; to establish an association between the different contributing factors and colonization. Material and methods: Samples were collected from 70 patients hospitalized in the Clinic of Oral and Maxillo-Facial Surgery, by rinsing the mouth with sterile saline; historical data were also collected. The samples were analyzed at the Microbiology Laboratory of the University of Medicine and Pharmacy of Tîrgu Mureș, using Sabouraud agar medium. For each isolate, the antifungigram for Fluconazole and Voriconazole was performed following the CLSI standards. Results: From the 70 samples 45.7% were positive for 11 different yeast species. Regarding predisposing factors, most importantly, smoking was significantly associated with Candida colonization (OR = 2.34; 95% CI = 1.42-3.84; p <0.05). Other factors, such as radiotherapy, oral hygiene or antibiotics, are related, but not statistically significant in our study. Candida albicans was the predominant species (38.8%). The testing of Candida albicans and non-albicans to Fluconazole showed an increased resistance (52.4%) in both cases, while the resistance to Voriconazole was 50% and 12.5%, respectively. Conclusions: Colonization of the oral cavity with Candida is present in about half of the patients with OMF conditions, and this is probably not only due to classical predisposing factors, but also due to chronic oral pathology and to several risk factors like smoking or radiotherapy.

Sign in / Sign up

Export Citation Format

Share Document