Evaluation of relationship between the Centella asiatica (Linn) fresh leaf extract induced spatial learning and memory enhancement and increased body weight gain in neonatal and adult rats

10.5580/1d05 ◽  
2008 ◽  
Vol 5 (2) ◽  
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Spatial Learning ◽  
Leaf Extract ◽  
Body Weight Gain ◽  
Centella Asiatica ◽  
Spatial Learning And Memory ◽  
Adult Rats ◽  
Memory Enhancement ◽  
Fresh Leaf

Early nutritional changes induce sexually dimorphic long-term effects on body weight gain and the response to sucrose intake in adult rats

Metabolism ◽  
2012 ◽  
Vol 61 (6) ◽  
pp. 812-822 ◽  
Author(s):  
Esther Fuente-Martín ◽  
Miriam Granado ◽  
Cristina García-Cáceres ◽  
Miguel A. Sanchez-Garrido ◽  
Laura M. Frago ◽  
...  
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Body Weight Gain ◽  
Sexually Dimorphic ◽  
Sucrose Intake ◽  
Long Term Effects ◽  
Adult Rats ◽  
Nutritional Changes

Postnatal intracerebroventricular exposure to neuropeptide Y causes weight loss in female adult rats

2003 ◽  
Vol 284 (6) ◽  
pp. R1560-R1566 ◽  
Author(s):  
Amit Varma ◽  
Jing He ◽  
Lisa Weissfeld ◽  
Sherin U. Devaskar
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Food Intake ◽  
Neuropeptide Y ◽  
Body Weight Gain ◽  
Sprague Dawley ◽  
Adult Rats ◽  
Sprague Dawley Rats ◽  
Old Adult ◽  
Arcuate Nuclei

We investigated the effect of repetitive postnatal (2–7 days) intracerebroventricular administration of neuropeptide Y (NPY) on food intake and body weight gain in the 3- to 120-day-old Sprague-Dawley rats. NPY caused a 32% transient increase in body weight gain with elevated circulating insulin concentrations within 24 h. This early intervention led to the persistence of hyperinsulinemia and relative hyperleptinemia with euglycemia in the 120-day-old female alone. This perturbation was associated with 50% suppression in adult female hypothalamic NPY concentrations and a 50–85% decline in NPY immunoreactivity in the paraventricular and arcuate nuclei. This change was paralleled by a ∼20% decline in food intake and body weight gain at 60 and 120 days. However, when exogenous NPY was stereotaxically reinjected into the paraventricular nucleus of the ∼120-day-old adult females who were pretreated with NPY postnatally, an increase in food intake and body weight gain was noted, attesting to no disruption in the NPY end-organ responsivity. We conclude that postnatal intracerebroventricular NPY has long-lasting effects that predetermine the resultant adult phenotype in a sex-specific manner.

scholarly journals A New Look at an Old Drug: Cumulative Effects of Low Ribavirin Doses in Amphetamine-Sensitized Rats

2020 ◽  
Vol 26 (31) ◽  
pp. 3884-3894
Author(s):  
Branka Petković ◽  
Srđan Kesić ◽  
Slavica Ristić ◽  
Željko Pavković ◽  
Jelena Podgorac ◽  
...  
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Motor Activity ◽  
Body Weight Gain ◽  
Antiviral Treatment ◽  
Repeated Treatment ◽  
Adult Rats ◽  
Male Wistar Rats ◽  
Time Required ◽  
The Brain

Background: Psychotic states related to psychostimulant misuse in patients with hepatitis C virus infection may complicate acceptance and reaction to antiviral treatment. This observation equally applies to the widely used ribavirin therapy. Objective: We examined psychomotor and body weight gain responses to low ribavirin doses after cessation of intermittent amphetamine treatment in adult rats to assess its role in neurobehavioral outcome during psychostimulant withdrawal. Method: The model of amphetamine-induced (1.5 mg/kg/day, i.p., 7 consecutive days) motor sensitization and affected body weight gain was established in adult male Wistar rats. Then, additional cohort of amphetaminesensitized rats was subjected to saline (0.9% NaCl; 1 mL/kg/day; i.p.) or ribavirin (10, 20 and 30 mg/kg/day, i.p.) treatment for 7 consecutive days. Animals’ motor activity in a novel environment was monitored after the 1st and the 7th saline/ribavirin injection. Body weight gain was calculated as appropriate. Determination and quantification of ribavirin in the brain tissue were performed also. Results: The 1st application of ribavirin to amphetamine-sensitized rats affected/decreased their novelty-induced motor activity only at a dose of 30 mg/kg. After the 7th application, ribavirin 30 mg/kg/day still decreased, while 10 and 20 mg/kg/day increased novelty-induced motor activity. These behavioral effects coincided with the time required to reach maximum ribavirin concentration in the brain. Body weight gain during withdrawal was not influenced by any of the doses tested. Conclusion: Ribavirin displays central effects that in repeated treatment, depending on the applied dose, could significantly influence psychomotor response but not body weight gain during psychostimulant/amphetamine withdrawal.

scholarly journals Centella asiatica (L.) Leaf Extract Treatment During the Growth Spurt Period Enhances Hippocampal CA3 Neuronal Dendritic Arborization in Rats

2006 ◽  
Vol 3 (3) ◽  
pp. 349-357 ◽  
Author(s):  
K. G. Mohandas Rao ◽  
S. Muddanna Rao ◽  
S. Gurumadhva Rao
Keyword(s):  
Body Weight ◽  
Leaf Extract ◽  
Centella Asiatica ◽  
Growth Spurt ◽  
Fresh Leaf ◽  
Dendritic Length ◽  
Branching Points ◽  
Dendritic Branching ◽  
Hippocampal Ca3 ◽  
Ca3 Neurons

Centella asiatica(CeA) is a creeping plant growing in damp places in India and other Asian countries. The leaves of CeA are used for memory enhancement in the Ayurvedic system of medicine, an alternative system of medicine in India. In this study, we have investigated the effect during the rat growth spurt period of CeA fresh leaf extract treatment on the dendritic morphology of hippocampal CA3 neurons, one of the regions of the brain concerned with learning and memory. Neonatal rat pups (7 days old) were fed with 2, 4 or 6 ml kg−1 body weight of fresh leaf extract of CeA for 2, 4 or 6 weeks. After the treatment period the rats were killed, their brains were removed and the hippocampal neurons were impregnated with silver nitrate (Golgi staining). Hippocampal CA3 neurons were traced using a camera lucida, and dendritic branching points (a measure of dendritic arborization) and intersections (a measure of dendritic length) were quantified. These data were compared with data for age-matched control rats. The results showed a significant increase in the dendritic length (intersections) and dendritic branching points along the length of both apical and basal dendrites in rats treated with 4 and 6 ml kg−1 body weight per day of CeA for longer periods of time (i.e. 4 and 6 weeks). We conclude that the constituents/active principles present in CeA fresh leaf extract have a neuronal dendritic growth stimulating property; hence, the extract can be used for enhancing neuronal dendrites in stress and neurodegenerative and memory disorders.

scholarly journals EFFECTS OF TULSI LEAF EXTRACT ON BODY WEIGHT GAIN IN BROILER PRODUCTION

2016 ◽  
Vol 14 (1) ◽  
pp. 21-25 ◽  
Author(s):  
M. N. Hasan ◽  
M. Mostofa ◽  
M. G. Sorwar ◽  
M. T. Hasan ◽  
K. Das ◽  
...  
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Treatment Group ◽  
Leaf Extract ◽  
Body Weight Gain ◽  
Control Group ◽  
Live Body Weight ◽  
Significant Difference ◽  
Group A ◽  
Group B

The objective of this research was to evaluate the effect of tulsi leaf (Ocimum sanctum) extract supplementation in drinking water as a growth promoter in broiler chickens. A total of 40 Cobb-500 broiler chicks (day-old) were purchased from local hatchery (Nourish Poultry and Hatchery Ltd.). After seven days of acclimatization chicks were randomly divided into two groups, A (n=20) and B (n=20). The group A was kept as a control and not treated. The group B was supplemented with tulsi leaf extract with feed and water. Weekly observations were recorded for live body weight gain up to 5th weeks and hematological tests were performed at 35th day’s age of broiler to search for hematological changes between control (A) and treatment (B) groups. The initial body weight of groups A and B on 1st day of this experiment were 41.00±1.78 gm and 41.50±2.35 gm, respectively and after 35th day of experiment final body weight were 1640± 74.83 gm and 1920± 33.91 gm, respectively and economics of production were analyzed and found that net profit per broiler was Tk. 21.46 and Tk. 32.29, respectively. The treatment group B was recorded statistically significant (at 1% level) increased (16.97%) for live body weight than that of control group A. The hematological parameters total erythrocyte count (TEC), erythrocyte sedimentation rate (ESR), packed cell volume (PCV) and hemoglobin (Hb) estimation value of treatment group shows significant difference, while hemoglobin (Hb) estimation does not show significant difference from control group. The results suggest that better growth performance could be achieved in broilers supplemented with tulsi leaf extract.

scholarly journals Performa Ayam Broiler yang Diberi Ekstrak Daun Jambu Mete (Anacardium occidentale Linn) dalam Air Minum

2021 ◽  
Vol 19 (1) ◽  
pp. 19-23
Author(s):  
S Khothijah ◽  
Edi Erwan ◽  
E Irawati
Keyword(s):  
Drinking Water ◽  
Body Weight ◽  
Weight Gain ◽  
Water Consumption ◽  
Leaf Extract ◽  
Body Weight Gain ◽  
Anacardium Occidentale ◽  
Broiler Performance ◽  
Randomized Design ◽  
Completely Randomized Design

Cashew leaves (Anacardium occidentale Linn) is a plant that can be used as a natural antibiotic because it contains flavonoids, tannins, anacardiol acid, elagic acid, phenol compounds, cardol, and methyl cardol. The aim of this study was to determine the effect of giving several levels of consumption of cashew leaf extract in drinking water on the performance of broilers including ration consumption, drinking water consumption, body weight gain, and ration conversion. This study used 80 doc broilers which were divided randomly based on a completely randomized design  with 5 treatments and 4 replications. The treatments given were P0 (0% cashew leaf extract as a control), P1 (5% cashew leaf extract in 1 L of water), P2 (10% cashew leaf extract in 1 L of water), P3 (15% cashew leaf extract in 1 L of water) and P4 (20% cashew leaf extract in 1 L of water). The variables observed were ration consumption, drinking water consumption, body weight gain and broiler ratio conversion. The results showed that inclusion of cashew leaf extract up to 20% in drinking water had a significant effect (p<0.05) on drinking water consumption, but no significant effect on ration consumption, body weight gain, and ration conversion.  It was concluded that giving cashew leaf extract in drinking water up to 20% had no effect on the broiler performance, in terms of ration consumption, body weight gain and ration conversion. Key words:        broiler chicken, cashew leaf extract, ration consumption, drinking water consumption, body weight gain, ratio conversion

PENGEMBANGAN TANAMAN RAMI (Boehmeria nivea L. Gaud) DAN PEMANFAATAN LIMBAH DAUN RAMI UNTUK PENGGEMUKKAN DOMBA WONOSOBO

2018 ◽  
Vol 16 (2) ◽  
pp. 201-210
Author(s):  
Muryanto Muryanto ◽  
Pita Sudrajad ◽  
Amrih Prasetyo
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Plant Development ◽  
Body Weight Gain ◽  
Survey Methods ◽  
The Body ◽  
Boehmeria Nivea ◽  
Central Java ◽  
Potential Capacity ◽  
The Given

The aim of the study was to determine the development of ramie plants (Boehmeria nivea L. Gaud) and the effect of using ramie leaves on feed on the body weight gain of Wonosobo Sheep (Dombos). Research on the development of ramie plants using survey methods in the area of ramie plant development in Wonosobo Regency. While the research on the use of ramie leaves for fattening was carried out in Butuh Village, Kalikajar District, Wonosobo Regency in 2018. 21 male Dombos were divided into 3 feed treatments with forage proportions of 70%, 50% and 30 ramie leaves respectively. %. The results showed that currently ramie plants were being developed in Wonosobo Regency by CV. Ramindo Berkah Persada Sejahtera in Gandok Village, Kalikajar District, Wonosobo Regency, Central Java. Until now the area of the crop has reached 13 ha. Of this area will produce ramie leaves 195,000 kg / year. If one sheep needs 4 kg of ramie / tail / day leaves, then the potential capacity of sheep is 135 heads / year, if the given one is 50% then the Jurnal Litbang Provinsi Jawa Tengah, Volume 16 202 Nomor 2 – Desember 2018potential capacity is 270 heads / year and if it is reduced again to 25% of ramie leaves then the potential capacity 440 heads / year. The use of ramie leaves as a feed for Wonosobo Sheep fattening can be given as much as 30% in fresh form.

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