scholarly journals Biometric features and content of phenolic compounds of roseroot (Rhodiola rosea L.)

2016 ◽  
Vol 85 (3) ◽  
Author(s):  
Artur Adamczak ◽  
Waldemar Buchwald ◽  
Agnieszka Gryszczyńska
Keyword(s):  
Folk Medicine ◽  
Raw Material ◽  
Rhodiola Rosea ◽  
Diagnostic Feature ◽  
Active Compounds ◽  
Plant Parts ◽  
Plant Groups ◽  
Biometric Measurements ◽  
Chemical Groups ◽  
Important Diagnostic Feature

Roseroot (<em>Rhodiola rosea</em> L.) belongs to important herbs in folk medicine of Scandinavia, Russia, Mongolia, and China. Its therapeutic usage is mainly associated with the adaptogenic properties of this species. Roseroot is characterized by high morphological, phytochemical, and genetic differentiation. The aim of the present work was to determine the biometric and phytochemical co-variability of this taxon. Samples of <em>Rh. rosea</em> were collected from 4-year-old experimental field cultivation established by rhizome division in western Poland. For each plant, the biometric measurements of the clumps, shoots, leaves, and rhizomes with roots were carried out. In the underground plant parts (raw material), the contents of the main active compounds (phenylpropanoids, phenylethanoids, phenolic acids, and catechins) were determined by the HPLC-DAD method. <em>K</em>-means clustering analysis showed three well-separated plant groups of <em>Rh. rosea</em> that differed significantly in the level of most of the investigated components. It was interesting that in the raw material with a high content of phenylethanoids, a low level of phenyl­propanoids was found, and vice versa. These chemical groups clearly differed in luxuriance of plants, too. The important diagnostic feature was also the degree of leaf serration. The morphological and phytochemical co-variability of roseroot was confirmed by the correlations detected between some active compounds (especially catechins and rosavin) and biometric traits describing the size and serration of leaves, the size of clumps and shoots as well as the weight of the raw material.

scholarly journals The Anti-Rheumatoid Arthritis Property of the Folk Medicine Dianbaizhu (Gaultheria leucocarpa var. yunnanensis, Ericaceae)

2014 ◽  
Vol 9 (12) ◽  
pp. 1934578X1400901 ◽  
Author(s):  
Meng Xie ◽  
Yi Lu ◽  
Cheng Yan ◽  
Rui Jiang ◽  
Weirui Liu ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Tumor Necrosis ◽  
Folk Medicine ◽  
Plant Parts ◽  
Effective Components ◽  
Water Fractions ◽  
Anti Inflammatory ◽  
Preferred Species ◽  
Necrosis Factor ◽  
Inflammatory Effect

The Chinese folk medicine Dianbaizhu, consisting of Gaultheria species, is widely used for the treatment of rheumatoid arthritis by several minority nationalities. The species and plant parts of this genus used as Dianbaizhu in clinical application are confused. In order to elucidate the species and the medicinal parts, as well as to ascertain the effective components and the probable optimal source of Dianbaizhu, the different plant parts and polarity fractions of its mainstream species, G. leucocarpa var. yunnanensis were investigated. The inhibition of nitric oxide and tumor necrosis factor produced in macrophage J774 were used to assess the anti-inflammatory effect of those samples. G. leucocarpa var. yunnanensis may be the preferred species for anti-RA effect. The underground parts of this taxon showed the best anti-inflammatory and anti-RA activities; the n-butanol and water fractions of the underground parts may be the most anti-RA active.

scholarly journals HPLC study of phenolic compounds in Mirabilis jalapa raw material

Pharmacia ◽  
2020 ◽  
Vol 67 (3) ◽  
pp. 145-152
Author(s):  
Dhurgham Khalid Abed Sarray ◽  
Liliia M. Horiacha ◽  
Iryna O. Zhuravel ◽  
Andrii I. Fedosov
Keyword(s):  
Phenolic Compounds ◽  
Folk Medicine ◽  
Total Content ◽  
Hplc Method ◽  
Raw Material ◽  
Control Methods ◽  
Quantitative Content ◽  
Different Types ◽  
Mirabilis Jalapa ◽  
Hplc Study

Mirabilis jalapa is a popular decorative plant valued for its beautiful multicolored flowers. Folk medicine in various countries applies Mirabilis jalapa as anti-microbial, anti-inflammatory, diuretic, spasmolytic drug. Chemical composition of different types of Mirabilis jalapa has not yet been adequately studied which is an obstacle for its application in medicine. The qualitative composition and quantitative content of phenolic compounds were studied by the HPLC method. The performed experiment revealed presence of hydroxycinnamic acids, flavonoids, isoflavonoids and coumarins in tested herb. The content of phenolic compounds was the highest in Mirabilis jalapa flowers, counting as much as 2977.41 ± 59.55 µg/mg. Total content of phenolic compounds in Mirabilis jalapa herb was 304.25 ± 6.08 µg/mg, in fruits – 67.92 ± 1.36 µg/mg, and in roots – 12.44 ± 0.25 µg/mg. Quantitatively neochlorogenic acid dominated in flowers, chlorogenic acid in fruits, whereas Mirabilis jalapa herb mostly contained rutin and hyperoside. The obtained results will be useful in the development of quality control methods for Mirabilis jalapa herb and manufacture of drug preparations on its basis.

Tarczyca bocznokwiatowa (Scutellaria lateriflora) – znaczenie w medycynie tradycyjnej i pozycja we współczesnej fitoterapii

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Inga Kwiecień ◽  
Beata Kawka ◽  
Halina Ekiert
Keyword(s):  
Chemical Composition ◽  
North American ◽  
Folk Medicine ◽  
Raw Material ◽  
Study Results ◽  
Phenylpropanoid Glycosides ◽  
Scutellaria Lateriflora ◽  
Sedative Action ◽  
Main Components

American skullcap (Scutellaria lateriflora L.) has long been used as a medicine by North American Indian tribes. A monograph of Scutellariae lateriflorae herba was included in the American Herbal Pharmacopoeia in 2009. This raw material is very popular in North America because of its sedative action. It is also highly valued in Australia, while in Europe, it has been widely used until now in the United Kingdom. The main components of the herb of this plant species include flavonoids specific for the Scutellaria genus, mostly baicalein, baicalin, wogonin, scutellarin. They are accompanied by other groups of compounds: diterpenoids – neoclerodan derivatives, γ-aminobutyric acid, melatonin, serotonin, catalpol, phenolic acids, phenylpropanoid glycosides (mostly verbascoside) and essential oil. Studies of chemical composition and investigation of medicinal activity of this raw material confirmed its uses known from North American folk medicine. Study results proved most of all a significance of flavonoid compounds present in the raw material for its documented biological activity. The aim of the paper is to review the present knowledge on chemical composition and medicinal significance of this very valuable plant. The research team from the Department of Pharmaceutical Botany JU MC initiated biotechnological studies of this species. Its microshoots successfully grown in vitro produce considerable amounts of specific flavonoids (mostly baicalin and wogonoside) and verbascoside, and in future they can be an alternative rich source of these compounds for pharmaceutical and cosmetic applications.

scholarly journals Myrica esculenta Buch.-Ham. ex D. Don: A Natural Source for Health Promotion and Disease Prevention

Plants ◽  
2019 ◽  
Vol 8 (6) ◽  
pp. 149 ◽  
Author(s):  
Atul Kabra ◽  
Natália Martins ◽  
Rohit Sharma ◽  
Ruchika Kabra ◽  
Uttam Singh Baghel
Keyword(s):  
Health Promotion ◽  
High Performance ◽  
Folk Medicine ◽  
Plant Biotechnology ◽  
Future Research ◽  
Synthetic Seed ◽  
Therapeutic Effects ◽  
Active Components ◽  
Plant Parts ◽  
Myrica Esculenta

Myrica esculenta (Myricaceae) is a popular medicinal plant most commonly found in the sub-tropical Himalayas. It is widely used in folk medicine to treat several ailments such as asthma, cough, chronic bronchitis, ulcers, inflammation, anemia, fever, diarrhea, and ear, nose, and throat disorders. Due to its multidimensional pharmacological and therapeutic effects, it is well recognized in the ayurvedic pharmacopeia. However, the recent upsurge in M. esculenta use and demand has led to illicit harvesting by the horticultural trade and habitat loss, pushing the plant to the brink of extinction. Thus, the present review aims to provide updated information on M. esculenta botany, ethnomedicinal uses, phytochemistry, pharmacological effects, toxicity, and conservation methods, as well as also highlight prospective for future research. Particular emphasis is also given to its antioxidant potential in health promotion. In-depth literature was probed by searching several sources via online databases, texts, websites, and thesis. About 57 compounds were isolated and identified from M. esculenta, and the available reports on physicochemical parameters, nutritional and high-performance thin-layer chromatography analysis of bioactive plant parts are portrayed in a comparative manner. Friendly holistic conservation approaches offered by plant biotechnology applications, such as micropropagation, germplasm preservation, synthetic seed production, and hairy root technologies are also discussed. Nonetheless, further studies are needed to propose the mechanistic role of crude extracts and other bioactives, and even to explore the structure–function relationship of active components.

scholarly journals Qualitative and Quantitative Analysis of Different Rhodiola rosea Rhizome Extracts by UHPLC-DAD-ESI-MSn

2019 ◽  
Vol 87 (2) ◽  
pp. 8 ◽  
Author(s):  
Fabian Alperth ◽  
Ivana Turek ◽  
Sandra Weiss ◽  
Dietmar Vogt ◽  
Franz Bucar
Keyword(s):  
Qualitative Analysis ◽  
Folk Medicine ◽  
Epigallocatechin Gallate ◽  
Extraction Methods ◽  
Rhodiola Rosea ◽  
Cinnamyl Alcohol ◽  
Long Time ◽  
Marker Compounds ◽  
Hydrolysis Of ◽  
High Ethanol

Rhodiola rosea has been used in folk medicine as ethanolic macerates for a long time. This study aims to provide a quantitative and qualitative analysis and comparison of different ethanolic Rhodiola rosea rhizome macerates (35%, 70%, and 96% v/v) and accelerated solvent extraction (ASE) extracts prepared with 85% methanol, in order to shed light on the effectivity of different extraction methods. Extract samples were analyzed by UHPLC-DAD-ESI-MSn on a ZORBAX SB-C18 column (100 × 2.1 mm, 1.8 μm) with a mobile phase consisting of water + 0.1% formic acid and acetonitrile. Qualitative analysis lead to the tentative identification of 18 compounds: Two cyanogenic glycosides (rhodiocyanoside A, lotaustralin), three phenylethanoids (salidroside, viridoside, 2-phenylethyl-vicianoside), two procyanidin and catechin derivatives (epigallocatechin-epigallocatechin gallate, epigallocatechin-3-O-gallate), five phenylpropanoids (cinnamyl alcohol, rosarin, rosavin, rosin, cinnamyl-(6’-O-β-d-xylopyranosyl)-O-β-glucopyranoside), two monoterpene alcohols (rhodioloside E, rosiridin) and four flavonols (rhodionidin, rhodiosin, rhodionin, kaempferol). Quantity was determined for salidroside, cinnamyl alcohol and its three major glycosides (rosarin, rosavin, rosin), as well as three flavonols (rhodionidin, rhodiosin, rhodionin). Methanolic ASE proved to be the superior extraction method for different substance groups. For macerates, high ethanol content increased yield and lowered hydrolysis of glycosides during extraction, but ethanolic macerates still showed low reproducibility and high fluctuations in quantity of marker compounds salidroside and rosavins, as well as flavonols. Rhodiola rosea rhizomes of wild origins seemed to underly great variability in chemical composition dependent on grow site.

Zenker’s diverticulum: a rare clinical condition with unusual oral manifestation

2020 ◽  
Vol 13 (10) ◽  
pp. e239248
Author(s):  
Anuj Dadhich ◽  
Harish Saluja ◽  
Seemit Shah ◽  
Kumar Nilesh
Keyword(s):  
Unusual Case ◽  
Clinical Manifestations ◽  
Zenker’S Diverticulum ◽  
Diagnostic Feature ◽  
Zenker's Diverticulum ◽  
Oral Manifestation ◽  
Oral Mucosal Lesions ◽  
Oral Symptoms ◽  
Oral Presentations ◽  
Important Diagnostic Feature

Oral mucosa exhibit clinical manifestations of a variety of systemic conditions and can serve as an indicator of overall health of an individual. Various systemic conditions like autoimmune, endocrine and haematological disorders can present with oral mucosal lesions, which can serve as an important diagnostic feature. These oral lesions can vary from oral ulceration, bleeding gums, xerostomia, chronic glossitis, to erosion and sensitivity of teeth. It is important that a clinician must be aware of the oral presentations of systemic conditions, so that timely diagnosis can be made and the necessary treatment is executed. This paper presents an unusual case of severe oral mucosal ulcerations and dysphagia in an elderly patient diagnosed with Zenker’s diverticulum. Patient was relieved of all oral symptoms once the underlying gastrointestinal tract pathology was diagnosed and surgically corrected.

scholarly journals Medicinal plants used by the Kaiowá and Guarani indigenous populations in the Caarapó Reserve, Mato Grosso do Sul, Brazil

2005 ◽  
Vol 19 (1) ◽  
pp. 39-44 ◽  
Author(s):  
Norlene Regina Bueno ◽  
Rachel Oliveira Castilho ◽  
Reginaldo Brito da Costa ◽  
Arnildo Pott ◽  
Vali J. Pott ◽  
...  
Keyword(s):  
Wound Healing ◽  
Abdominal Pain ◽  
Medicinal Plants ◽  
Folk Medicine ◽  
Indigenous Populations ◽  
Ethnobotanical Survey ◽  
Mato Grosso ◽  
Plant Parts ◽  
Medicinal Properties ◽  
Mato Grosso Do Sul

This ethnobotanical survey carried out with the Kaiowá and Guarani populations in the Caarapó Reserve (Mato Grosso do Sul, Brazil) showed that 34 plant species of 22 families with medicinal properties, are used for treating diverse pathologies. Local names in Portuguese and Guarani are provided, along with therapeutic indications, modes of preparation, and a description of the plant parts used. These folk-medicine plants have been mostly used for the treatment of influenza, abdominal pain, fever and rheumatism, and for wound healing.

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