The impact of regional express trains from Moscow on population mobility

2020 ◽  
pp. 27-38
Author(s):  
A. A. Romashina
Keyword(s):  
Spatial Behavior ◽  
Population Mobility ◽  
System Transformation ◽  
Speed Increase ◽  
Settlement Structure ◽  
Migration Potential ◽  
And Migration ◽  
The Individual ◽  
The Impact

The paper is concerned with settlement system transformation in response to transport speed increase and changing the conditions of commuting. The article discusses the role of the individual spatial mobility as a part of settlement structure by the example of directions from Moscow to Tver’, Nizhny Novgorod, Orel, Belgorod, Kursk, where projects of significant railroad speed increase were operated in the 2010s. Transport accessibility improvement between Moscow and listed regional centers, caused by the launch of regional express trains, changed the spatial behavior of the inhabitants of these regions. The study of settlement structure transformation in response to transport connection speed increase was based on dynamics data of various types of trains passenger flows and the results of sociological surveys of regional express trains passengers. Conclusions are drawn about the role of commuting in the settlement structure and the factors of their transformation, depending on the speed characteristics, existing settlement structure and other geographical characteristics of the territory. The influence of these factors was different on the considered directions. Some of mentioned projects affected intra- (Tver’) and inter-agglomeration mobility (Nizhny Novgorod). Some cities (Oryol, Kursk, Belgorod) are characterized by small effects on commuting due to it’s sensitivity to the distance from Moscow and migration potential.

DLK1-DIO3 Region as a Source of Candidate Tumor Suppressor miRNAs in Papil- Lary Thyroid Carcinoma

2020 ◽  
Author(s):  
Leonardo Augusto Marson ◽  
Letícia Ferreira Alves ◽  
Micheli Severo Sielski ◽  
Cristina Pontes Vicente ◽  
Edna Teruko Kimura ◽  
...  
Keyword(s):  
Tumor Suppressor ◽  
Thyroid Carcinoma ◽  
Genomic Region ◽  
And Migration ◽  
The Individual ◽  
Computational Resources ◽  
The Impact ◽  
Tumor Suppressor Mirnas ◽  
Shed Light

Abstract Background: DLK1-DIO3 genomic region comprises one of the largest microRNA (miRNAs) clusters in human genome. In previous studies we showed the downregulation of several miRNAs from the genomic region in papillary thyroid carcinoma (PTC). Due to the large number of miRNAs within this region the individual contribution of these molecules to PTC development and progression remains unclear. Methods: We used different computational resources to clarify the contribution of DLK1-DIO3-derived miRNAs to PTC. Results: Our analysis suggests that 12 miRNAs from this region cooperate to modulate distinct cancer-relevant biological processes, potentially responding for most of the impact of DLK1-DIO3-derived miRNAs to PTC development and progression. The overexpression of miR-485-5p in two PTC cell lines decreased proliferation and migration, confirming the biological relevance of in silico data. Conclusion: Our results shed light on the role of DLK1-DIO3 region, harboring several tumor suppressor miRNAs in thyroid cancer and open perspectives for the functional exploration of these miRNAs as therapeutic targets for PTC.

The Role of Threat and Economic Uncertainty in Support for Scottish Independence

2014 ◽  
Vol 23 (1) ◽  
pp. 103-124 ◽  
Author(s):  
Daniel Kopasker
Keyword(s):  
Economic Consequences ◽  
Perceived Threat ◽  
Constitutional Change ◽  
Lack Of Information ◽  
Economic Expectations ◽  
Scottish Independence ◽  
The Individual ◽  
The Impact ◽  
Levels Of Support

Existing research has consistently shown that perceptions of the potential economic consequences of Scottish independence are vital to levels of support for constitutional change. This paper attempts to investigate the mechanism by which expectations of the economic consequences of independence are formed. A hypothesised causal micro-level mechanism is tested that relates constitutional preferences to the existing skill investments of the individual. Evidence is presented that larger skill investments are associated with a greater likelihood of perceiving economic threats from independence. Additionally, greater perceived threat results in lower support for independence. The impact of uncertainty on both positive and negative economic expectations is also examined. While uncertainty has little effect on negative expectations, it significantly reduces the likelihood of those with positive expectations supporting independence. Overall, it appears that a general economy-wide threat is most significant, and it is conjectured that this stems a lack of information on macroeconomic governance credentials.

scholarly journals National movement patterns during the COVID-19 pandemic in New Zealand: the unexplored role of neighbourhood deprivation

2021 ◽  
pp. jech-2020-216108 ◽  
Author(s):  
Malcolm Campbell ◽  
Lukas Marek ◽  
Jesse Wiki ◽  
Matthew Hobbs ◽  
Clive E Sabel ◽  
...  
Keyword(s):  
New Zealand ◽  
Mobile Phone ◽  
Well Being ◽  
Policy Debate ◽  
Population Mobility ◽  
Neighbourhood Deprivation ◽  
Movement Data ◽  
Spatial Inequalities ◽  
The Impact

BackgroundThe COVID-19 pandemic has asked unprecedented questions of governments around the world. Policy responses have disrupted usual patterns of movement in society, locally and globally, with resultant impacts on national economies and human well-being. These interventions have primarily centred on enforcing lockdowns and introducing social distancing recommendations, leading to questions of trust and competency around the role of institutions and the administrative apparatus of state. This study demonstrates the unequal societal impacts in population movement during a national ‘lockdown’.MethodsWe use nationwide mobile phone movement data to quantify the effect of an enforced lockdown on population mobility by neighbourhood deprivation using an ecological study design. We then derive a mobility index using anonymised aggregated population counts for each neighbourhood (2253 Census Statistical Areas; mean population n=2086) of national hourly mobile phone location data (7.45 million records, 1 March 2020–20 July 2020) for New Zealand (NZ).ResultsCurtailing movement has highlighted and exacerbated underlying social and spatial inequalities. Our analysis reveals the unequal movements during ‘lockdown’ by neighbourhood socioeconomic status in NZ.ConclusionIn understanding inequalities in neighbourhood movements, we are contributing critical new evidence to the policy debate about the impact(s) and efficacy of national, regional or local lockdowns which have sparked such controversy.

scholarly journals Factors affecting the organizational performance of manufacturing firms

2017 ◽  
Vol 9 ◽  
pp. 184797901771262 ◽  
Author(s):  
Ahmad Adnan Al-Tit
Keyword(s):  
Organizational Performance ◽  
Measurement Instrument ◽  
Manufacturing Firms ◽  
Factors Affecting ◽  
Mediating Role ◽  
Values And Beliefs ◽  
The Individual ◽  
The Impact ◽  
The Relationship

Numerous studies have been conducted to explore the individual effects of organizational culture (OC) and supply chain management (SCM) practices on organizational performance (OP) in different settings. The aim of this study is to investigate the impact of OC and SCM on OP. The sample of the study consisted of 93 manufacturing firms in Jordan. Data were collected from employees and managers from different divisions using a reliable and valid measurement instrument. The findings confirm that both OC and SCM practices significantly predict OP. The current study is significant in reliably testing the relationship between SCM practices and OP; however, it is necessary to consider cultural assumptions, values and beliefs as the impact of OC on OP is greater than the impact of SCM practices. Based on the results, future studies should consider the moderating and mediating role of OC on the relationship between SCM practices and OP.

Practitioner Review: Continuity and Change: The Fair Work Act in Aviation

2011 ◽  
Vol 53 (3) ◽  
pp. 392-401 ◽  
Author(s):  
Sue Bussell ◽  
John Farrow
Keyword(s):  
Industrial Relations ◽  
Safety Net ◽  
Aviation Industry ◽  
Continuity And Change ◽  
National Debate ◽  
New Development ◽  
Key Issues ◽  
The Individual ◽  
The Impact

This article begins by discussing the specific industrial relations challenges of the highly competitive aviation industry. It then reflects on the outcome of the recent intense national debate over industrial relations, exploring the consequences of that debate for practice and policy, and discusses some key issues that remain in play. Although the Fair Work Act 2009 may have come about as a reaction to what many perceive as the ‘excesses’ of Work Choices, the new Act does not so much ‘wind back the clock’ as represent a significant new development in Australia’s long and unique industrial relations history. This article will discuss the impact of the changes, to date, made by the Fair Work Act on one organization, including the expansion of the ‘safety net’, and how the new compromise between the role of the ‘collective’ and the role of the ‘individual’ struck by the Act has the potential to fundamentally change the nature and structure of bargaining. We offer these comments as practitioners who have worked under successive industrial relations regimes since the early 1980s.

The Evolution of the Role of U.S. School Nurses in Adolescent Mental Health at the Individual, Community, and Systems Level: An Integrative Review

2022 ◽  
pp. 105984052110681
Author(s):  
Ashwini R. Hoskote ◽  
Emily Croce ◽  
Karen E. Johnson
Keyword(s):  
Mental Health ◽  
Adolescent Mental Health ◽  
School Nurse ◽  
School Nurses ◽  
Integrative Review ◽  
School Nursing ◽  
Individual Level ◽  
The Individual ◽  
The Impact

School nurses are crucial to addressing adolescent mental health, yet evidence concerning their evolving role has not been synthesized to understand interventions across levels of practice (i.e., individual, community, systems). We conducted an integrative review of school nurse roles in mental health in the U.S. related to depressive symptoms, anxiety, and stress. Only 18 articles were identified, published from 1970 to 2019, and primarily described school nurses practicing interventions at the individual level, yet it was unclear whether they were always evidence-based. Although mental health concerns have increased over the years, the dearth of rigorous studies made it difficult to determine the impact of school nurse interventions on student mental health outcomes and school nurses continue to feel unprepared and under supported in this area. More research is needed to establish best practices and systems to support school nursing practice in addressing mental health at all levels of practice.

scholarly journals On the interrelations between migration and commuting

Stanovnistvo ◽  
2013 ◽  
Vol 51 (1) ◽  
pp. 69-90 ◽  
Author(s):  
Vesna Lukic
Keyword(s):  
Real Estate ◽  
Labour Market ◽  
Real Estate Market ◽  
Modern Trend ◽  
Population Mobility ◽  
Rural Settlements ◽  
Long Distance ◽  
And Migration ◽  
Vojvodina Province

In this paper, we emphasise the significance of studying the interrelations between commuting and migration. The aim of the paper is to point out the factors which affect these interrelations (demographic and socio-economic characteristics of migrants and commuters, labour market, real estate market, information, life style, etc.), with the special emphasis on the role of commuting distance onto the chosen mobility type. Besides theorethical frameworks and results of the selected foreign researches up to date, the overview of research of interrelations between migration and commuting in Serbia has also been presented. While earlier studies conducted by Gawryszenski (1978), Termote (1980) and Reitsma&Vergoossen (1987) pointed to the replacement of migration types between each other within country, in recent literature the interaction between migration and commuting has been studied in a trans-boundary context of the contemporary EU. Modern trend of long distance commuting instead of migration and the concept of substitution/replacement regarding migration and commuting have also been discussed. In Serbia, there is a positive correlation between commuting outflows and immigration in rural settlements of Vojvodina province. Namely, commuting and migration are complement, which is the characteristic of both processes sub-urbanisation and ex-urbanisation (Lukic, 2012). In addition to ownership of real estate and previous migration experience, marital status influenced the chosen mobility type in Serbia as well. Adjustment to changes of Serbian labour market is mostly conducted via migration (Miletic, Lukic, Miljanovic, 2011). Interrelations between migration and commuting are very significant due to the tendency of transformation of some commuters into migrants. This process has its consequences, both on demographic as well as the overall socio-economic development of the area of commuters? origin and destination. However, even though the surveys conducted in Serbia during the 1980s showed that around 30 per cent of commuters expressed desire to move to their place of work, the degree of realization of these intentions remained unknown. While in some countries traffic studies and data from the management of the enterprises are used as sources of data on commuting, the studies on the commuter population in Serbia are based solely onto two types of data sources. These are census and poll surveys. Although they have more potential than the official statistics for the analysis of the links between migration and commuting and other characteristics of commuters, poll surveys on this topic in Serbia are relatively rare due to financial and organizational obstacles. Indeed, the last major survey was conducted in the 1980s. Therefore, even though the interrelations between migration and commuting have been confirmed, there is still a lot of space for their research indicating the need for further methodology developments in researching these types of population mobility.

scholarly journals Chemo-mechanical Diffusion Waves Orchestrate Collective Dynamics of Immune Cell Podosomes

2021 ◽  
Author(s):  
Ze Gong ◽  
Koen van den Dries ◽  
Alessandra Cambi ◽  
Vivek Shenoy
Keyword(s):  
Actin Polymerization ◽  
Immune Cell ◽  
Wave Dynamics ◽  
Diffusion Waves ◽  
Mechanical Diffusion ◽  
Mechanical Waves ◽  
The Individual ◽  
The Impact ◽  
Cell Mechanosensing

Immune cells, such as macrophages and dendritic cells, can utilize podosomes, actin-rich protrusions, to generate forces, migrate, and patrol for foreign antigens. In these cells, individual podosomes exhibit periodic protrusion and retraction cycles (vertical oscillations) to probe their microenvironment, while multiple podosomes arranged in clusters demonstrate coordinated wave-like spatiotemporal dynamics. However, the mechanisms governing both the individual vertical oscillations and the coordinated oscillation waves in clusters remain unclear. By integrating actin polymerization, myosin contractility, actin diffusion, and mechanosensitive signaling, we develop a chemo-mechanical model for both the oscillatory growth of individual podosomes and wave-like dynamics in clusters. Our model reveals that podosomes show oscillatory growth when the actin polymerization-associated protrusion and the signaling-associated myosin contraction occur at similar rates, while the diffusion of actin monomers within the cluster drives mesoscale coordination of individual podosome oscillations in an apparent wave-like fashion. Our model predicts the influence of different pharmacological treatments targeting myosin activity, actin polymerization, and mechanosensitive pathways, as well as the impact of the microenvironment stiffness on the wavelengths, frequencies, and speeds of the chemo-mechanical waves. Overall, our integrated theoretical and experimental approach reveals how collective wave dynamics arise due to the coupling between chemo-mechanical signaling and actin diffusion, shedding light on the role of podosomes in immune cell mechanosensing within the context of wound healing and cancer immunotherapy.

The migration component in the demographic development of Russia in the post-war period (1951–2020)

2021 ◽  
Vol 17 (2) ◽  
pp. 235-242
Author(s):  
Leonid Rybakovsky ◽  
Vladimir Savinkov ◽  
Natalia Kozhevnikova
Keyword(s):  
First Century ◽  
Demographic Development ◽  
Demographic Dynamics ◽  
Growth Decline ◽  
Migration Potential ◽  
Natural Movement ◽  
Post War ◽  
And Migration ◽  
The Impact ◽  
Migration Component

The article discusses possible combinations of the impact on the dynamics of the population of migration growth (decline) and natural decline (increase). Variants of combinations with the corresponding values of natural and migration movements are shown using examples of the demographic dynamics of Russia. Reliable information about the migration movement of the population refers only to the time that began in the 50s. It is distributed over periods that differ in the nature of the impact of the reproductive and migration components on demographic dynamics. During these periods spanning seventy years, the country's population increased by almost 44 million. In the first 25 years, there was a migration decline, more than offset by natural population growth. Then migration, along with natural movement, acted as a component of population dynamics. Due to natural growth, the population increased to the 1951 level. by 33.8 million people. The migration component accounted for 10.6 million people. Their ratio was 3/4 to 1/4. It is shown that in the second half of the tenth years of the twenty-first century, Russia entered a difficult demographic time for it, aggravated by the fact that by now in the new abroad the migration potential oriented towards Russia has significantly decreased

The Role of the Individual in ICT Standardisation

2015 ◽  
pp. 244-261
Author(s):  
Kai Jakobs
Keyword(s):  
Literature Review ◽  
Social Shaping Of Technology ◽  
The Social ◽  
Social Shaping ◽  
Technical Factors ◽  
Standards Development ◽  
The Individual ◽  
The Impact

This chapter discusses the influence individuals have in the ICT standards development process. The chapter draws upon ideas underlying the theory of the Social Shaping of Technology (SST). Looking through the SST lens, a number of non-technical factors that influence ICT standards development are identified. A literature review on the role of the individual in ICT standards setting and a case study of the IEEE 802.11 Working Group (WG) show that in a standards body's WG, the backgrounds, skills, attitudes, and behaviour of the individual WG members are crucially important factors. Yet, the case study also shows that in most cases employees tend to represent the ideas and goals of their respective employer. The chapter observes that the non-technical factors are ignored all too often in the literature. It argues that a better understanding of the impact and interplay of these factors, specifically including the skills and attitudes of the WG members, will have significant implications both theoretical and managerial.

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