Do age and time of practice predict the development of life skills among  youth futsal practitioners?

La práctica del deporte ha sido considerada una de las principales herramientas para el desarrollo de habilidades para la vida entre los jóvenes participantes en el deporte. Este estudio transversal investigó el papel predictivo de la edad y el tiempo de práctica en el desarrollo de habilidades para la vida entre 207 practicantes de futsal masculinos, con edades comprendidas entre 12 y 17 años, del estado de Pernambuco, Brasil. Los instrumentos utilizados fueron la Escala de habilidades para la vida deportiva y un cuestionario semiestructurado. El análisis de los datos se realizó a través del Análisis de varianza multivariante, la correlación de Spearman y la Regresión múltiple (p <.05). Los resultados mostraron una diferencia significativa (p <.05; rango η2 .036-.142) en todas las habilidades para la vida según el grupo de edad, evidenciando puntuaciones más altas para los adolescentes mayores. Además, los adolescentes más experimentados mostraron puntajes más altos en la meta sentada (p = .001, η2 = .074); resolución de problemas (p = .013, η2 = .042), comunicación (p = .003, η2 = .054) y habilidades para la vida total (p = .002, η2 = .057). Hubo una correlación significativa (p <.05) y positiva entre la edad y casi todas las subescalas de habilidades para la vida. La regresión múltiple reveló que solo la edad presentaba predicciones positivas hacia las habilidades para la vida. Se puede concluir que la edad es un predictor del desarrollo de habilidades para la vida entre los jóvenes practicantes de fútbol sala. The practice of sports has been considered one of the main tools for the life skills development among youth sport participants. This cross-sectional study investigated the predicting role of age and time of practice in the development of life skills among 207 male futsal practitioners, aged between 12 and 17 years, from the state of Pernambuco, Brazil. The instruments used were the Life Skills Scale for Sports and a semi-structured questionnaire. Data analysis was conducted through Multivariate Analysis of Variance, Spearman’s correlation and Multiple Regression (p<.05). The results showed significant difference (p<.05; η2 range .036-.142) in all life skills according to age group, evidencing higher scores for older adolescents. Further, more experienced adolescents showed higher scores at goal seating (p=.001, η2=.074); problems solving (p=.013, η2=.042), communication (p=.003, η2=.054) and total life skills (p=.002, η2=.057). There was significant (p<.05) and positive correlation between age and almost all life skills subscales. Multiple regression revealed only age presented positive prediction toward life skills. It can be concluded that age is a predictor of life skills development among youth futsal practitioners. A prática esportiva tem sido considerada uma das principais ferramentas para o desenvolvimento de habilidades para a vida entre jovens praticantes de esportes. Este estudo transversal investigou o papel preditivo da idade e do tempo de prática no desenvolvimento de habilidades para a vida em 207 praticantes de futsal do sexo masculino, com idades entre 12 e 17 anos, do estado de Pernambuco, Brasil. Os instrumentos utilizados foram a Escala de Habilidades para a Vida Esportiva e um questionário semiestruturado. A análise dos dados foi realizada por meio da Análise Multivariada de Variância, correlação de Spearman e Regressão Múltipla (p <0,05). Os resultados mostraram diferença significativa (p <0,05; η2 variando de 0,036 a 0,142) em todas as habilidades para a vida de acordo com a faixa etária, evidenciando escores mais altos nos adolescentes mais velhos. Além disso, os adolescentes mais experientes apresentaram pontuações mais altas nos assentos para as metas (p = 0,001; η2 = 0,074); resolução de problemas (p = 0,013, η2 = 0,042), comunicação (p = 0,003, η2 = 0,054) e habilidades totais para a vida (p = 0,002, η2 = 0,057). Houve correlação significativa (p <0,05) e positiva entre idade e quase todas as subescalas de habilidades para a vida. A regressão múltipla revelou que apenas a idade apresentou predição positiva em relação às habilidades para a vida. Pode-se concluir que a idade é um preditor do desenvolvimento de habilidades para a vida entre jovens praticantes de futsal.

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Teacher Discrimination Reduces School Performance of African American Youth: Role of Gender

Brain Sciences ◽

10.3390/brainsci8100183 ◽

2018 ◽

Vol 8 (10) ◽

pp. 183 ◽

Cited By ~ 7

Author(s):

Shervin Assari ◽

Cleopatra Howard Caldwell

Keyword(s):

African American ◽

School Performance ◽

African American Youth ◽

National Sample ◽

Cross Sectional Study ◽

Cross Sectional ◽

Grade Point ◽

Significant Difference ◽

Males And Females

Background: Gender may alter African Americans’ vulnerability to discrimination. The type of outcomes that follow exposure to discrimination may also be gender-specific. Although teacher discrimination is known to deteriorate school performance, it is yet unknown whether male and female African American youth differ in the effect of teacher discrimination on school performance. Objective: This cross-sectional study explored the moderating role of gender on the effect of teacher discrimination on school performance in a national sample of African American youth. Methods: The National Survey of American Life-Adolescent Supplement (NSAL-A) enrolled a nationally representative sample (n = 810) of 13–17-year-old African American youth. Demographic factors, socioeconomic status, teacher discrimination, and school performance (grade point average, GPA) were measured. Linear multivariable regression models were applied for data analysis. Results: Males and females reported similar levels of perceived teacher discrimination. In the pooled sample, higher teacher discrimination was associated with lower school performance among African American youth (b = −0.35; 95% confidence interval (CI) = −0.49 to −0.22). Gender interacted with perceived teacher discrimination (b = 12; 95% CI = 0.24–2.02), suggesting a significant difference between males and females in the magnitude of the association between perceived teacher discrimination and GPA. In stratified models, perceived teacher discrimination was associated with worse school performance of females (b = −12; 95% CI = −0.03 to −2.78) but not males (b = 0.01; 95% CI = −0.07 to 0.08). Conclusion: In line with previous studies, gender was found to alter the vulnerability of African American youth to perceived discrimination. African American boys and girls may differ in their sensitivity to the effects of teacher discrimination on school performance.

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Assessment of role of mandibular third molar in lower anterior crowding among orthodontic patients of Kathmandu Nepal

Orthodontic Journal of Nepal ◽

10.3126/ojn.v10i3.35486 ◽

2020 ◽

Vol 10 (3) ◽

pp. 21-26

Author(s):

Bashu Dev Pant ◽

Anjana Rajbhandari ◽

Resina Pradhan ◽

Manju Bajracharya ◽

Surendra Maharjan ◽

...

Keyword(s):

Third Molar ◽

Cross Sectional Study ◽

Third Molars ◽

Chi Square ◽

Cross Sectional ◽

Anterior Crowding ◽

Mandibular Third Molar ◽

Significant Difference ◽

Orthodontic Patients

Introduction: Crowding in mandibular arch increases with increasing age and etiology of crowding is multifactorial in nature. Role of mandibular third molar in lower anterior crowding remains a topic of controvery over a period of century. The objective of this study was to assess whether there is any correlation between presence of mandibular third molar position and lower anterior crowding. Materials and Method: On the basis of third molar position one hundred and six sample of pretreatment orthodontic patients aged between 17 to 38 years were divided into erupted, erupting and agenesis group. The study was conducted in Peoples Dental College and Hospital from January 2020 to March 2020 after obtaining ethical approval from the institutional review committee. This cross-sectional study was done on dental casts and orthopantomogram; brass wire was used for measuring arch length and digital vernier caliper for measuring tooth material with modified segmental arch analysis method. Result: Among 106 samples collected 55 (51.88%) were female and 51(48.11%) were male and the mean age was 21.53 ± 3.91 years, Chi square and ANOVA test was used for Statistical analysis. This study showed no statistically significant differences between third molar position and lower anterior crowding on right (P= 0.68) and left side (P = 0.45). The study also showed that association between the third molar position and lower anterior crowding is more on left side compared to right side. Conclusion: Mandibular third molars have not statistically significant difference in lower anterior crowding so, extraction of third molars for relieving the anterior crowding is not justifiable

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The Role of Pressure and Duration of Dive on Lung Physiology in Professional and Non-Professional Divers

Jurnal Respirologi Indonesia ◽

10.36497/jri.v40i2.104 ◽

2020 ◽

Vol 40 (2) ◽

pp. 103-112

Author(s):

Jerry Indra Setiawan ◽

Suradi Suradi ◽

Yusup Subagio Sutanto

Keyword(s):

Vital Capacity ◽

Cross Sectional Study ◽

Professional Group ◽

Sectional Study ◽

Test Statistic ◽

Cross Sectional ◽

Lung Physiology ◽

Significant Difference ◽

Normally Distributed

Backgrounds: Professional divers have a greater lung volume than non-professional divers in higher force vital capacity (FVC) and force expiratory flow in 1 second (FEV1) values. The purpose of this study is to analyse the effect of pressure and duration of diving on changes in lung physiology in professional divers and non-professional divers. Methods: This is a cross sectional study on the personnel of the Indonesian Navy Dislambair Koarmada II Surabaya and RSAL personnel of dr. Ramelan Navy Hospital in Lakesla Surabaya in March-April 2019. Samples was collected with purposive sampling. This study used unpaired subjects with the independent t-test statistic analysis if the data is normally distributed and the Mann-Whitney U test if the data is not normally distributed Results: There was a significant difference in the professional divers group compared to non-professional divers group in the values of FVC (P=0.042) and FEV1 (P=0.040) at 1.3 ATA for 10 minutes and the FEV1 (P=0.049) for 20 minutes. No significant differences in FVC (P=0.092) at 1.3 ATA pressure for 20 minutes. There were no significant differences in FVC (P=0.865), FEV1 (P=0.659) at 1.5 ATA pressure for 10 minutes and FVC (P=0.858) and FEV1 (P=0.857) for 20 minutes. Conclusions: The different pressure in non-professional group could reduce the FEV1 value. There was a difference in the FVC value of the professional diver group and non-professional divers at a pressure of 1.5 ATA for 10 minutes. (J Respir Indo. 2020; 40(2): 103-12)

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The Role of Maternal Progesterone and Estradiol Levels in Predicting the Success of Induction of Labour: A Preliminary Study

Indonesian Journal of Obstetrics and Gynecology ◽

10.32771/inajog.v7i2.867 ◽

2019 ◽

pp. 126-129

Author(s):

Kanadi Sumapraja ◽

Hilda R Badruddin

Keyword(s):

Cross Sectional Study ◽

Induction Of Labour ◽

Health Clinic ◽

Cross Sectional ◽

Induction Group ◽

Significant Difference ◽

Preliminary Study ◽

Larger Sample ◽

Estradiol Levels

Objective: to evaluate whether maternal progesterone and estradiol levels could be used to predictthe success ofinduction of labour (IOL) Methods:This cross-sectional study was conducted at the Women’s Health Clinic as well as delivery suite of Dr. Cipto Mangunkusumo Hospital during the period of May 2016 to April 2017. Blood samples of term pregnant women who were indicated for IOL wereobtainedbefore birth. Results:A total 44 subject were recruited in this study.Of these, 24 subjects had successful IOL while the other 20 subjects had IOL failure. There was no significant difference of progesterone among both groups (66,7% vs 75%, p=0,55). The estradiol levels in subjects who successfully performed induction had an average of 16,916.28 ± 2,574.75 pg/mL which did not differ significantly from the failed of induction group with estradiol levels of 14,832.24 ± 2374.47 pg/mL (p = 0,65). Conclusion:We found no significant association between both maternal progesterone and estradiol levels and the success rate of IOL. Further studies with larger sample sizes are required to confirm whether progesterone and estradiol play pivotal roles in the success of IOL. Keywords: progesterone, estradiol, induction of labour Tujuan: mengevaluasi kadar progesteron dan estradiol ibu sebagai prediktor kesuksesan induksi persalinan Metode: Penelitian ini menggunakan desain potong lintang yang berlangsung pada bulan Mei 2016 hingga April 2017 di Poliklinik dan IGD Kebidanan Rumah Sakit Umum Pusat Rujukan Nasional Cipto Mangunkusumo. Pasien hamil aterm yang dilakukan induksi persalinan dan memenuhi kriteria penelitian akan diambil sampel darah sebelum persalinan. Hasil: Dari 44 subjek yang mengikuti penelitian, 24 subjek berhasil dilakukan induksi persalinan dan 20 subjek gagal.Tidakterdapatperbedaanbermaknapadakadarprogesterone Antarakeduagrup(66,7% vs 75%, p=0,55). Kadar estradiol padapasien yang berhasildilakukaninduksimemiliki rata-rata 16.916,28 + 2.574,75pg/mL yang tidakberbedajauhdengankadar estradiol pasien yang gagalinduksiyaitu 14.832,24 + 2374,47pg/mL (p = 0,65). Kesimpulan: Tidakterdapat perbedaan bermakna antara kadar progesteron dan estradiol maternal terhadap keberhasilan induksi persalinan. Penelitian lebih lanjut dengan jumlah sampel yang lebih besar dibutuhkan untuk mengkonfirmasi hubungan ini dengan lebih baik. Kata kunci: progesteron, estradiol, induksi persalinan

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Serum Albumin Level as a Prognostic Marker for Covid-19 Positive Patients in Western Uttar Pradesh - A Cross Sectional Study

Journal of Evidence Based Medicine and Healthcare ◽

10.18410/jebmh/2021/39 ◽

2021 ◽

Vol 8 (04) ◽

pp. 204-207

Author(s):

Shreyansh Talera ◽

Saurabh Singhal ◽

Nishant Wadhera ◽

Mayank Arora ◽

Ravi Pratap

Keyword(s):

Serum Albumin ◽

Prognostic Marker ◽

Serum Albumin Level ◽

Uttar Pradesh ◽

Cross Sectional Study ◽

Albumin Level ◽

The Body ◽

Cross Sectional ◽

Significant Difference

BACKGROUND WHO has declared Coronavirus disease 2019 (Covid-19) as a pandemic. Covid-19 leads to sickness and death. Human serum albumin (HSA) is the most common circulating protein in the body having oncotic as well as non-oncotic properties. The role of albumin in death among Covid-19 subjects, especially in this part of the country has not been frequently reported. The aim of the study was to analyse the role of serum albumin level as prognostic marker for Covid-19 positive patients. METHODS The present study was conducted in the department of Medicine at Chhatrapati Shivaji Subharti Hospital, Subharti Medical College, Meerut, UP. The study comprised of 100 subjects who were Covid positive from May 2020 to July 2020. A detailed explanation was given to all the participating respondents regarding the study and their contribution to it. Covid-19 was diagnosed on the basis of the WHO interim guidelines. A questionnaire was prepared to collect the patients’ demographic profile. Patients date of admission and discharge was recorded along with the outcome i.e., whether patient expired or survived. Patients’ diagnosis was identified along with the comorbidity (if present). Laboratory investigations comprised of CBC and serum albumin detection. Data so collected was tabulated in an excel sheet, under the guidance of statistician. Collected data was analysed using Statistical Package for the Social Sciences (SPSS) software version 24 and the tests used were t test and Fisher’s exact test and the level of significance was set at p < 0.05. RESULTS The study comprised of 100 subjects, out of which 45 were males and 55 were females. The overall mean age of the study subjects was 37.52 years. In our study, mortality was 35.29 %, 9.33 % and 85.7 % of the subjects having Covid-19+ type 2 diabetes (T2DM), only Covid-19 and Covid-19+ hypertension respectively with statistically significant difference as p < 0.05. Albumin level was significantly lower in expired patients (2.99) as compared to survivors (3.85) as p < 0.05. Hospital stay was also higher in expired patients. CONCLUSIONS Covid-19 patients had low serum albumin levels and that might play a role in the survival of patient. KEYWORDS Covid-19, Mortality, Albumin

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Prevalence of Anxiety in Pregnancy during COVID 19 pandemic in Shree Birendra Hospital, Chhauni

Nepal Journal of Obstetrics and Gynaecology ◽

10.3126/njog.v16i1.37507 ◽

2021 ◽

Vol 16 (1) ◽

Author(s):

Shailaja Khadka ◽

Sumana Thapa ◽

Ratna Khatri ◽

Rosy Malla ◽

Sumana Thapa ◽

...

Keyword(s):

Pregnant Women ◽

Demographic Data ◽

Cross Sectional Study ◽

Demographic Variables ◽

Low Grade ◽

Cross Sectional ◽

Significant Difference ◽

Ethical Approval ◽

Almost All ◽

In Pregnancy

Aim: To determine the prevalence of anxiety in pregnancy during COVID19 pandemic in Shree Birendra Hospital, Chhauni Method: It is a cross sectional study conducted at Shree Birendra Hospital Chhauni from July to October 2020 following the ethical approval from IRC. All the pregnant women from first to last trimester attending outdoor visit were included; they were asked to fill up Beck Anxiety Index form. The level of anxiety was compared with demographic data like age, race, parity, and period of gestation, education and occupation. Data were analyzed by using SPSS 20 software. Results: A total of 385 presumably uninfected pregnant women were surveyed in 20-40 (28.45±3.95) years age group from 4 to 41 (27.15±9.4) weeks of pregnancy and 55.6% were multipara. Low-grade anxiety was found 99.5% (BAI= 3.06±3.66). Conclusions: Low-grade anxiety was found in almost all pregnant women during covid pandemic and there was no significant difference by demographic variables.

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Role of Impulsivity, Aggression in Alcohol Dependence – A Cross Sectional Study from Vellore, India

Journal of Evolution of Medical and Dental Sciences ◽

10.14260/jemds/2021/714 ◽

2021 ◽

Vol 10 (40) ◽

pp. 3520-3525

Author(s):

Pichaachari Rathika ◽

Kaliyan Veeramuthu ◽

Arumugam Subramanian Senthilkumar

Keyword(s):

Alcohol Dependence ◽

Hospital Admissions ◽

Age Of Onset ◽

Cross Sectional Study ◽

Drinking Behaviour ◽

Sectional Study ◽

Cross Sectional ◽

Public Health Burden ◽

Significant Difference

BACKGROUND Alcohol use disorder is one of the dangerous public health burden. The construct of impulsivity and its various dimensions in relation with aggression are relevant for understanding alcohol dependence and relapse. The goal of the study is to describe the role of impulsivity and aggression in the context of alcohol dependence. The purpose and implications of this study was to understand the human factors contributing to aggression and impulsivity and in providing advanced treatment programs. METHODS This cross-sectional study was discussed in detail and approved by the ethical committee of the Madras Medical College. The cases were selected consecutively from all the patients attending the outpatients as well as inpatient for the same after fulfilling the inclusion and exclusion criteria, within seven days of last intake of alcohol. The diagnosis was made according to International Classification of Diseases (ICD-10) criteria after ruling out psychotic disorder and other comorbid medical illnesses. Informed consent was obtained from all the patients and caregivers. Descriptive statistics used meticulously to measure the magnitude. RESULTS This study found significant positive correlation (P < 0.001) between impulsivity, aggression subtypes with alcohol dependence. Various subsets in Barrett impulsivity scale (BIS) and subsets of Buss Perry aggression scales (BPAS) had positive correlations. We found that as severity of dependence increases, impulsivity and aggression scores increases and vice versa. The comparison of means of illness variables within groups showed that there was no significant difference between groups in terms of age of onset of illness, last alcohol intake, number of hospital admissions, duration of abstinence and frequency of relapse. CONCLUSIONS This study describes the important role of behavioural model and disease model of alcoholism, 1,2 greatly stresses the inability to control the quantity and frequency of the drinking behaviour. There is higher level of connectivity between alcohol dependence with biological and behavioural indicators of impulsivity and aggression. 3 It supports that relapse is an acquired behaviour in which the individual is able to control his substance taking pattern through adequate cognitive behavioural techniques in addition to pharmacological treatment and also suggest more research needed in future to focus on causality and intervention. KEY WORDS Impulsivity, Aggression, Alcohol dependence, Relapse

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Level of awareness of dentists about the role of physiotherapy in temporomandibular disorders: a pilot study in Riyadh, Saudi Arabia

Bulletin of Faculty of Physical Therapy ◽

10.1186/s43161-020-00009-5 ◽

2020 ◽

Vol 25 (1) ◽

Author(s):

Afaf A. M. Shaheen ◽

Hajar Alhajri ◽

Noura Alrajeeb ◽

Ruba Almoammar ◽

Arwa Alyousef ◽

...

Keyword(s):

Pilot Study ◽

Temporomandibular Disorders ◽

Online Survey ◽

Multidisciplinary Approach ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Almost All ◽

Collaboration Awareness

Abstract Background Physiotherapy (PT) is a distinguished developing profession. It has a crucial role in treating temporomandibular disorders (TMD) as an effective intervention to reduce pain and improve TMD symptoms. Not all dentists are aware of the importance of collaboration with physiotherapists (PTs).Therefore, this study aimed to assess the level of dentists’ awareness about the role of PT in treating TMD, identify dentists’ willingness to collaborate with PTs, and create collaboration awareness. This cross-sectional study included Saudi dentists in Riyadh. An online survey was used to assess dentist’s awareness and their readiness to collaborate with PTs. Results Out of 1500 dentists, only 162 participated in the survey. About 46.9% of dentists were aware that PT can treat TMD. Generally, there was lack of awareness about the benefits of PT among dentists (61.8%), and 59.9% was not aware that the evidence suggested that PT can improve TMD symptoms. Only 29% referred patients to PT. Upon the completion of the survey, almost all dentists (97.5%) were likely to refer patients with TMD to PT, and 90.7% of them showed interest to learn more about collaborating with PTs. Conclusion The study concluded that, although 46.9% of the dentists are aware about the role of PT in treating TMD, there is a lack of awareness about the benefits of PT among the majority of them. The study helped to extend the awareness of surveyed dentists about the collaboration and multidisciplinary approach.

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Role of biomarkers in predicting prognosis of Coronavirus disease 2019 (COVID-19): A retrospective cross-sectional study: Perspective of a tertiary care hospital in India

World Journal of Advanced Research and Reviews ◽

10.30574/wjarr.2021.11.1.0300 ◽

2021 ◽

Vol 11 (1) ◽

pp. 081-090

Author(s):

Arushi Mohan ◽

Padmini SN ◽

Brunda MS ◽

Abhinaya Shekhar ◽

Paul Matthew ◽

...

Keyword(s):

Inflammatory Markers ◽

Cross Sectional Study ◽

Sectional Study ◽

C Reactive Protein ◽

Oxygen Requirement ◽

Cross Sectional ◽

Reactive Protein ◽

Significant Difference ◽

D Dimer

Background: COVID-19 is a novel disease triggered by the SARS-CoV-2 virus, a beta coronavirus similar to MERS-CoV and SARS CoV. Inflammatory markers have a vital role in the pathogenesis of nCOVID 19; understanding the importance of these inflammatory markers in determining disease status is essential given the impact of the disease on healthcare. Thus, being able to triage cases with minimal tests is momentous to capture, which we have investigated as per our study guidelines of the role of inflammatory markers such as D-dimer, CRP (C - reactive protein), Ferritin, LDH (Lactate Dehydrogenase) in patients with COVID 19. In addition, limited data is available comparing the utility of these inflammatory markers to predict the following parameters as the need for ICU, oxygen support requirement, and duration of in-hospital stay, which can help guide the management protocol. Aim: This study aims to determine markers associated with poor prognosis in patients with Coronavirus disease 2019 (COVID-19). Objectives: 1) To assess the inflammatory markers that are routinely investigated in COVID- 19 patients. 2) To determine the most probable factor to estimate severity in COVID- 19 and thus predict prognosis. Methods: This is a retrospective cross-sectional observational study of patients who tested SARS COV 2 positive by RT PCR. The laboratory inflammatory markers, namely Lactate Dehydrogenase, C reactive protein, D-dimer, Ferritin, were assessed in the selected patients, and their clinical data and demographic details were taken into account. The parameters considered for contributing to the severity included the number of days of stay in the hospital, oxygen requirement, and ICU needs. Analyses relied upon analysis of variance for cross-sectional study design and a P< 0.05 statistical significance criterion. Results: There was a statistically significant difference found between oxygen requirement and D dimer (p<0.001), LDH (p= 0.002), and CRP (p= 0.024). There was a statistically significant difference found between admission to ICU and D Dimer (p= 0.001). Conclusion: A statistically significant association between the increasing D-dimer levels and all the outcome measures considered was found. The D-dimer, LDH, and CRP help predict oxygen requirement, and all the inflammatory markers can predict the number of days of stay in the hospital.

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A clinical study from patient’s perspective: Motivation, Expectations, and Perception

Clinical Medicine (Russian Journal) ◽

10.18821/0023-2149-2017-95-8-751-757 ◽

2017 ◽

Vol 95 (8) ◽

pp. 751-757 ◽

Cited By ~ 1

Author(s):

Evgeny S. Kulikov ◽

I. A. Deev ◽

O. S. Kobyakova ◽

O. I. Zvonareva ◽

O. S. Fedorova ◽

...

Keyword(s):

Clinical Trials ◽

Cross Sectional Study ◽

Trial Participation ◽

Motivating Factors ◽

Cross Sectional ◽

Free Treatment ◽

The Russian Federation ◽

Almost All ◽

Medical Examinations

Introduction. Pharmaceutical market and clinical trials (CTs) industry are growing rapidly in Russia, but little is known about perceptions of patients involved in medical experimentation, about their expectations regarding trial participation, and associated fears and reservations. Material and methods. A multicenter cross-sectional study was conducted in different cities of the Russian Federation. Patients who had previous experience in CTs (or were enrolled in a CT at the time of this study) were asked to complete a questionnaire. Results. Likert-style questions were used to evaluate factors influencing the perception of CTs by the patients. The most important factors to decide whether to participate in the clinical trial or not for the patients included professional monitoring services, regular condition monitoring, better medical care, and free treatment. Three most significant factors that have adverse effect on the interest to participate in the study were: the risk of side effects, study of new medication and the risk of getting into the placebo group. The most important motivating factors to continue CTs for the patients were as follows permanent monitoring of condition, personal relationships with medical researchers, improvement of physical condition, as well as free medical examinations and medical assistance. Conclusion. Results of the study showed that expectations, motivations and experiences of patients participating in clinical trials in Russia are comparable with the world's data. The findings suggest more significant role of the researcher in almost all aspects of patient participation. After the end of the study the majority of respondents were still in contact with doctors.

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