scholarly journals Retrospective study of the effectiveness of different treatment methods for equine cheek teeth periodontal disease

2014 ◽  
Author(s):  
Kirsten Jackson ◽  
Lukas M. Weber ◽  
Marc Tennant
Keyword(s):  
Periodontal Disease ◽  
Dental Treatment ◽  
Treatment Options ◽  
Case Series ◽  
Small Sample ◽  
The Other ◽  
Periodontal Pocket ◽  
Confounding Effect ◽  
Pocket Depth ◽  
Treatment Methods

Reasons for performing the study. Equine periodontal disease is a common, often painful dental condition that may lead to premature tooth loss if left untreated [1,2,3]. At present little research has been done comparing different treatment methods for the condition to assist clinicians in making educated treatment decisions. Objectives. To compare the effectiveness of four commonly used treatment options for periodontal disease (on top of routine dental treatment and equilibration) to assess their merit in reducing periodontal pocket depth. Study Design. Retrospective case series. Methods. Four commonly used treatment options were compared: Removing feed material and disinfecting the periodontal pocket with dilute chlorhexidine and rinsing the mouth with chlorhexidine based mouthwash (‘Hexarinse’), ‘cleaned and disinfected’ (CD); CD plus the addition of metronidazole antibiotics into the periodontal pockets (M); M plus the addition of a polyvinyl siloxane temporary filling over the diastema (PVS); and diastema burring to widen the gap between the teeth, then PVS (DB). Pocket depth measurements were compared before and after treatment at treatment intervals between two and six months. Results. Treatment groups CD, M and PVS showed statistically significant reductions in pocket depth between visits. Mean reduction was greatest in the DB group, but this was not statistically significant. Additional analysis to compare effectiveness revealed a strong confounding effect of initial pocket depth. After taking this into account, there was some evidence that DB was associated with smaller improvements than the other treatments, however this result was based on a small sample size. Among the other treatments, no statistically significant differences in effectiveness were found. Conclusion. This study has shown that treatment methods CD, M and PVS are associated with statistically significant reductions in pocket depth. Due to the confounding effect of initial pocket depth, no clear differences in effectiveness were found between treatment methods.

scholarly journals Retrospective study of the effectiveness of four different treatments of equine cheek teeth periodontal disease

2016 ◽  
Author(s):  
Kirsten Jackson ◽  
Lukas M. Weber ◽  
Marc Tennant
Keyword(s):  
Periodontal Disease ◽  
Sample Size ◽  
Small Sample Size ◽  
Case Series ◽  
Small Sample ◽  
The Other ◽  
Periodontal Pocket ◽  
Confounding Effect ◽  
Pocket Depth ◽  
Treatment Methods

Reasons for performing the study. Equine cheek teeth periodontal disease is a common, often painful dental condition that may lead to premature tooth loss if left untreated. All cases of periodontal disease in this study were associated with diastemata, with the majority of cases being secondary or senile diastemata. At present limited objective information is available comparing different treatment methods for the condition to assist clinicians in making evidence-based treatment decisions. Objectives. To compare the effectiveness of four commonly used treatments for equine periodontal disease (additional to routine dental treatment and equilibration) to assess their merit in reducing periodontal pocket depth. Study design. Retrospective case series. Methods. Four commonly used equine periodontal treatments were compared: Removing feed material and lavaging the periodontal pocket with dilute chlorhexidine and rinsing the mouth with chlorhexidine based mouthwash (‘Hexarinse’), ‘clean and antiseptic lavage’ (CL); CL plus the addition of metronidazole antibiotics into the periodontal pockets (M); M plus the addition of a polyvinyl siloxane temporary filling over the diastema (PVS); and diastema widening to open the diastema and increase the interdental space between adjacent teeth, then PVS (DW). Periodontal pocket depth measurements were compared before and after treatment at treatment intervals between two and six months. Results. Treatment groups CL, M and PVS showed statistically significant reductions in pocket depth following treatment. Mean pocket depth reduction was greatest in the DW group (and this was the only group with no cases involving an increase in pocket depth), but this was based on a small sample size and was not statistically significant. Additional analysis to compare effectiveness revealed a strong confounding effect of initial pocket depth. After taking this into account, there was some evidence that DW was associated with smaller improvements than the other treatments, however this result was also based on a small sample size, and influenced by a small number of cases with particularly large improvements. Among the other treatments, no statistically significant differences in effectiveness were found. Conclusion. This study has shown that treatment methods CL, M and PVS are associated with statistically significant reductions in pocket depth. Due to the confounding effect of initial pocket depth, no clear differences in effectiveness were found between treatment methods.

scholarly journals Retrospective study of the effectiveness of four different treatments of equine cheek teeth periodontal disease

2016 ◽  
Author(s):  
Kirsten Jackson ◽  
Lukas M. Weber ◽  
Marc Tennant
Keyword(s):  
Periodontal Disease ◽  
Sample Size ◽  
Small Sample Size ◽  
Case Series ◽  
Small Sample ◽  
The Other ◽  
Periodontal Pocket ◽  
Confounding Effect ◽  
Pocket Depth ◽  
Treatment Methods

Reasons for performing the study. Equine cheek teeth periodontal disease is a common, often painful dental condition that may lead to premature tooth loss if left untreated. All cases of periodontal disease in this study were associated with diastemata, with the majority of cases being secondary or senile diastemata. At present limited objective information is available comparing different treatment methods for the condition to assist clinicians in making evidence-based treatment decisions. Objectives. To compare the effectiveness of four commonly used treatments for equine periodontal disease (additional to routine dental treatment and equilibration) to assess their merit in reducing periodontal pocket depth. Study design. Retrospective case series. Methods. Four commonly used equine periodontal treatments were compared: Removing feed material and lavaging the periodontal pocket with dilute chlorhexidine and rinsing the mouth with chlorhexidine based mouthwash (‘Hexarinse’), ‘clean and antiseptic lavage’ (CL); CL plus the addition of metronidazole antibiotics into the periodontal pockets (M); M plus the addition of a polyvinyl siloxane temporary filling over the diastema (PVS); and diastema widening to open the diastema and increase the interdental space between adjacent teeth, then PVS (DW). Periodontal pocket depth measurements were compared before and after treatment at treatment intervals between two and six months. Results. Treatment groups CL, M and PVS showed statistically significant reductions in pocket depth following treatment. Mean pocket depth reduction was greatest in the DW group (and this was the only group with no cases involving an increase in pocket depth), but this was based on a small sample size and was not statistically significant. Additional analysis to compare effectiveness revealed a strong confounding effect of initial pocket depth. After taking this into account, there was some evidence that DW was associated with smaller improvements than the other treatments, however this result was also based on a small sample size, and influenced by a small number of cases with particularly large improvements. Among the other treatments, no statistically significant differences in effectiveness were found. Conclusion. This study has shown that treatment methods CL, M and PVS are associated with statistically significant reductions in pocket depth. Due to the confounding effect of initial pocket depth, no clear differences in effectiveness were found between treatment methods.

scholarly journals Detection of highly and minimally leukotoxic Actinobacillus actinomycetemcomitans strains in patients with periodontal disease

2003 ◽  
Vol 17 (2) ◽  
pp. 183-188 ◽  
Author(s):  
Sheila Cavalca Cortelli ◽  
Antonio Olavo Cardoso Jorge ◽  
José Roberto Cortelli ◽  
Shawn Francis Jordan ◽  
Violet Ibyola Haraszthy
Keyword(s):  
Periodontal Disease ◽  
Strong Association ◽  
Aggressive Periodontitis ◽  
Actinobacillus Actinomycetemcomitans ◽  
Periodontal Pocket ◽  
Chain Reaction ◽  
Chi Square ◽  
Pocket Depth ◽  
Polymerase Chain ◽  
Brazilian Cohort

This study examined the prevalence of highly and minimally leukotoxic Actinobacillus actinomycetemcomitans in patients with periodontal disease. Pooled subgingival plaque samples from 136 patients with some form of periodontal disease were examined. Subjects were between 14 and 76 years of age. Clinical examinations included periodontal pocket depth (PD), plaque index (PI) and bleeding index (BI). The obtained plaque samples were examined for the presence of highly or minimally leukotoxic A. actinomycetemcomitans strains by the polymerase chain reaction (PCR). Chi-square and logistic regression were performed to evaluate the results. Forty-seven subjects were diagnosed with gingivitis, 70 with chronic periodontitis and 19 with aggressive periodontitis. According to chi-square there was no significant correlation detected between PD (chi2 = 0.73), PI (chi2 = 0.35), BI (chi2 = 0.09) and the presence of the highly leukotoxic A. actinomycetemcomitans. The highly leukotoxic A. actinomycetemcomitans strains were correlated with subjects that were 28 years of age and younger (chi2 = 7.41). There was a significant correlation between highly leukotoxic A. actinomycetemcomitans and aggressive periodontitis (chi2 = 22.06). This study of a Brazilian cohort confirms the strong association between highly leukotoxic A. actinomycetemcomitans strains and the presence of aggressive periodontitis.

scholarly journals Retrieval of a periodontally compromised tooth by allogeneic grafting of mesenchymal stem cells from dental pulp: A case report

2018 ◽  
Vol 46 (7) ◽  
pp. 2983-2993 ◽  
Author(s):  
Beatriz Hernández-Monjaraz ◽  
Edelmiro Santiago-Osorio ◽  
Edgar Ledesma-Martínez ◽  
Andrés Alcauter-Zavala ◽  
Víctor Manuel Mendoza-Núñez
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Periodontal Disease ◽  
Dental Pulp ◽  
Enzymatic Digestion ◽  
Periodontal Pocket ◽  
Mineral Density ◽  
Culture Dish ◽  
Pocket Depth ◽  
Lower Premolar

Objective To report a case of successful allogeneic grafting of mesenchymal dental pulp stem cells (DPSCs) as preliminary findings in a patient with periodontal disease enrolled into clinical trial ISRCTN12831118. Methods Mesenchymal stem cells from the dental pulp of a deciduous tooth from a 7-year-old donor were separated from the pulp chamber and processed via enzymatic digestion and centrifugation. DPSCs were passaged and cultured on a 35 × 13 mm culture dish in minimum essential medium-alpha, without supplementation. After reaching 80% confluency, 5 x 106 allogeneic DPSCs in 250 µl phosphate buffered saline were seeded onto a dry scaffold of lyophilized collagen-polyvinylpyrrolidone sponge placed in the left lower premolar area of a 61-year-old patient with periodontal disease. Surgical access to the lower premolar area was achieved using the flap technique. Results At 3 and 6 months following allogeneic graft, the patient showed no sign of rejection and exhibited decreases in tooth mobility, periodontal pocket depth and bone defect area. Bone mineral density had increased at the graft site. Conclusions Regenerative periodontal therapy using DPSCs of allogeneic origin may be a promising treatment for periodontal disease-induced bone defects.

scholarly journals Non-Incised Papilla Surgical Approach and Leukocyte Platelet-Rich Fibrin in Periodontal Reconstruction of Deep Intrabony Defects: A Case Series

2021 ◽  
Vol 18 (5) ◽  
pp. 2465
Author(s):  
Guillermo Pardo-Zamora ◽  
José Antonio Moreno-Rodríguez ◽  
Antonio J. Ortiz-Ruíz
Keyword(s):  
Soft Tissue ◽  
Surgical Approach ◽  
Case Series ◽  
Periodontal Pocket ◽  
Central Incisor ◽  
Intrabony Defects ◽  
Pocket Depth ◽  
Platelet Rich Fibrin ◽  
Residual Defect ◽  
One Year

We present the preliminary results of the treatment of teeth with a deep, non-contained periodontal residual defect, vestibular bone dehiscence, and soft tissue recession, by combining an apical non-incised papilla surgical approach (NIPSA) to the defect and leukocyte platelet-rich fibrin (L-PRF) in the vestibular aspect. Four patients (upper left first premolar, upper left central incisor, upper right central incisor and upper right lateral incisor) have been treated. At one year of follow up, all cases showed a considerable reduction in the periodontal pocket depth, a gain in clinical attachment and no bleeding on probing, as well as an improvement in the marginal soft tissue minimizing soft tissue contraction (recession and/or loss of papilla) and improving soft tissue architecture. NIPSA plus L-PRF seem to improve clinical outcomes in deep non-contained intrabony defects associated with soft tissue recession.

scholarly journals The Antimicrobial Treatment of Periodontal Disease: Changing the Treatment Paradigm

1999 ◽  
Vol 10 (3) ◽  
pp. 245-275 ◽  
Author(s):  
W.J. Loesche
Keyword(s):  
Periodontal Disease ◽  
Antimicrobial Agents ◽  
Disease Risk ◽  
Antimicrobial Treatment ◽  
Periodontal Pocket ◽  
Gingival Tissue ◽  
Central Feature ◽  
New Paradigm ◽  
Pocket Depth ◽  
Periodontal Infection

Over the last 100 years, methods of surgical periodontal treatment have enjoyed a history of success in improving oral health. The paradigm of care is based on the "non-specific plaque hypothesis"-that is, the overgrowth of bacterial plaques cause periodontal disease, and the suppression of this overgrowth reduces disease risk. The central feature of this approach to care is the removal of inflamed gingival tissue around the teeth to reduce periodontal pocket depth, thereby facilitating plaque removal by the dentist and by the patient at home. Over the last 30 years, with the recognition that periodontal disease(s) is caused by specific bacteria and that specific antimicrobial agents can reduce or eliminate the infection, a second paradigm has developed. This new paradigm, the "specific plaque hypothesis", focuses on reducing the specific bacteria that cause periodontal attachment loss. The contrast between the two paradigms can be succinctly stated as follows: The antimicrobial therapy reduces the cause, while the surgical therapy reduces the result of the periodontal infection. The specific plaque hypothesis has two important implications. First, with the increasing attention to evidence-based models for prevention, treatment, outcome assessment, and reimbursement of care, increasing attention and financial effort will be channeled into effective preventive and treatment methods. Second, the recent observations that periodontal infections increase the risk of specific systemic health problems, such as cardiovascular disease, argue for the prevention and elimination of these periodontal infections. This review highlights some of the evidence for the specific plaque hypothesis, and the questions that should be addressed if antimicrobial agents are to be used responsively and effectively.

Canine Periodontal Disease Control Using a Clindamycin Hydrochloride Gel

2011 ◽  
Vol 28 (4) ◽  
pp. 224-229 ◽  
Author(s):  
Thomas P. Johnston ◽  
Pravakar Mondal ◽  
Dhananjay Pal ◽  
Scott MacGee ◽  
Arnold J. Stromberg ◽  
...  
Keyword(s):  
Periodontal Disease ◽  
Fusobacterium Nucleatum ◽  
Positive Influence ◽  
Periodontal Pocket ◽  
Gingival Index ◽  
Pocket Depth ◽  
Cleaning Procedure ◽  
Before And After ◽  
The Matrix ◽  
Gingival Cells

Stabilizing or reducing periodontal pocket depth can have a positive influence on the retention of teeth in dogs. A topical 2 % clindamycin hydrochloride gel (CHgel) was evaluated for the treatment of periodontal disease in dogs. The CHgel formulation provides for the sustained erosion of the matrix, but also flows into the periodontal pocket as a viscous liquid, and then rapidly forms a gel that has mucoadhesive properties and also may function as a physical barrier to the introduction of bacteria. A professional teeth cleaning procedure including scaling and root planing was done in dogs with one group receiving CHgel following treatment. Periodontal health was determined before and after the procedure including measurement of periodontal pocket depth, gingival index, gingival bleeding sites, and number of suppurating sites. There was a statistically significant decrease in periodontal pocket depth (19 %), gingival index (16 %), and the number of bleeding sites (64 %) at 90-days in dogs receiving CHgel. Additionally, the number of suppurating sites was lower (93 %) at 90-days for the group receiving CHgel. The addition of CHgel effectively controlled the bacterial burden (e.g., Fusobacterium nucleatum) at both day 14 and 90. Gingival cells in culture were shown to rapidly incorporate clindamycin and attain saturation in approximately 20-minutes. In summary, a professional teeth cleaning procedure including root planning and the addition of CHgel improves the gingival index and reduces periodontal pocket depth.

scholarly journals Relationship between Oral Malodor and the Global Composition of Indigenous Bacterial Populations in Saliva

2010 ◽  
Vol 76 (9) ◽  
pp. 2806-2814 ◽  
Author(s):  
Toru Takeshita ◽  
Nao Suzuki ◽  
Yoshio Nakano ◽  
Yoshihiro Shimazaki ◽  
Masahiro Yoneda ◽  
...  
Keyword(s):  
Microbial Community Composition ◽  
Hierarchical Cluster ◽  
Bacterial Count ◽  
The Other ◽  
Periodontal Pocket ◽  
Total Bacterial Count ◽  
Oral Malodor ◽  
Pocket Depth ◽  
Bacterial Populations ◽  
Two Parameters

ABSTRACT Oral malodor develops mostly from the metabolic activities of indigenous bacterial populations within the oral cavity, but whether healthy or oral malodor-related patterns of the global bacterial composition exist remains unclear. In this study, the bacterial compositions in the saliva of 240 subjects complaining of oral malodor were divided into groups based on terminal-restriction fragment length polymorphism (T-RFLP) profiles using hierarchical cluster analysis, and the patterns of the microbial community composition of those exhibiting higher and lower malodor were explored. Four types of bacterial community compositions were detected (clusters I, II, III, and IV). Two parameters for measuring oral malodor intensity (the concentration of volatile sulfur compounds in mouth air and the organoleptic score) were noticeably lower in cluster I than in the other clusters. Using multivariate analysis, the differences in the levels of oral malodor were significant after adjustment for potential confounding factors such as total bacterial count, mean periodontal pocket depth, and tongue coating score (P < 0.001). Among the four clusters with different proportions of indigenous members, the T-RFLP profiles of cluster I were implicated as the bacterial populations with higher proportions of Streptococcus, Granulicatella, Rothia, and Treponema species than those of the other clusters. These results clearly correlate the global composition of indigenous bacterial populations with the severity of oral malodor.

scholarly journals Periodontal disease in ideal weight, overweight and obese patients in different gender of a Tertiary Care Hospital in Pakistan.

2019 ◽  
Vol 26 (09) ◽  
pp. 1461-1465
Author(s):  
Zaheer Hussain Chachar ◽  
Gotam Das ◽  
Shabir Ahmed ◽  
Maimuna Khokhar ◽  
Muhammad Ilyas Shaikh ◽  
...  
Keyword(s):  
Periodontal Disease ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Normal Weight ◽  
Periodontal Pocket ◽  
Care Hospital ◽  
Obese Patients ◽  
Ideal Weight ◽  
Pocket Depth ◽  
Female Ratio

Introduction: Chronic periodontitis is the inflammation of the gingiva extending into the supporting structure of teeth. Periodontal disease is characterized by loss of clinical attachment due to destruction of the periodontal ligament and loss of the adjacent supporting bone eventually leading to tooth loss. Obesity is unusual or unnecessary fat deposition that may harm health. A number of hypotheses for biological reactions among obesity and periodontal disease have been anticipated. Objectives: To determine the frequency of ideal weight, overweight and obese patients in dental outdoor of FMH Pakistan. Study Design: Cross-Sectional Study. Setting:  Medical Outdoor at Tertiary Care Hospital in Pakistan. Period: 15th January to 14th July 2017. Material & Methods: A total 100 patients came to the medical outpatients department between 25 to 45 years of age were included. Patients satisfying the inclusion criteria, subjects BMI score were checked by classifying him/her obese, overweight or normal weight. Periodontal pocket depth was observed by WHO probe of one tooth from each male and female patient. Frequency of periodontal disease was seen in subjects. Results: Age range in his study was from 25 to 45 years with mean age of 36.9 ±7.51 years. In 100 patients 66 (66%) were females & 34 (34%) were males and with male to female ratio 1.9:1. Periodontal disease was seen in 47 female patients (71%) and in 24 male patients (70%). Pocket depth was present in over weight and obese patients more than normal weight. Conclusion: current study accomplished that there is positive association of periodontal disease in overweight and obese patients. The incidence of periodontal disease was highest in female obese patients.

scholarly journals Endothelial dysfunction and periodontal hemodynamic disturbances in young patients with nicotine dependence

2012 ◽  
Vol 11 (2) ◽  
pp. 70-75
Author(s):  
A. V. Naumov ◽  
V. A. Vyshivanyuk ◽  
A. L. Vertkin
Keyword(s):  
Endothelial Dysfunction ◽  
Periodontal Disease ◽  
Nicotine Dependence ◽  
Augmentation Index ◽  
Reactive Hyperemia ◽  
Young Patients ◽  
Periodontal Pocket ◽  
Group Differences ◽  
Pocket Depth ◽  
Periodontal Index

Aim.To investigate the association between periodontal hemodynamic disturbances and systemic endothelial dysfunction (ED); to assess the effectiveness of various toothpastes for periodontal disease prevention in patients with nicotine dependence.Material and methods.In total, 120 young individuals aged 22—28 years were divided into 2 groups, according to the presence or absence of nicotine dependence. All participants underwent ED assessment with the EndoPAT device. Microcirculation (MC) was assessed with the high-frequency Doppler ultrasound system MinimaxDoppler-K. Patients with nicotine dependence were divided into 2 subgroups. Subgroup A was recommended to use the R.O.C.S. toothpaste Anti-Tobacco (WDS Laboratories) twice a day, while Subgroup B participants were recommended to use the toothpaste Colgate Advanced Whitening with polishing micro-crystals (ColgatePalmolive Poland) twice a day.Results.Significant between-group differences were observed for reactive hyperemia index and augmentation index. ED severity was higher in smoking participants. Velocity and volume parameters of periodontal MC were lower in smokers. The use of each specialized toothpaste was associated with improved periodontal MC, decreased prevalence of periodontal pathology-related complaints, reduced periodontal pocket depth, and decreased periodontal index values; however, the Anti-Tobacco toothpaste was more effective.Conclusion.Young smokers demonstrated а more severe ED and disturbed periodontal MC, which manifested in a more advanced periodontal disease.

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