Patient Characteristics Related to Phlebitis in the East Coast of Peninsular Malaysia Hospital

Author(s):  
Azlina Daud ◽  
Fatimah Mohamad

The insertion of peripheral intravenous catheters (PIVCs) is common for treatment among hospitalized patients. However, this procedure usually fails before the end of therapy because of several complications, including phlebitis. Therefore, this study aimed to determine the incidence and associated factors of phlebitis among patients with PIVC. A prospective cohort study was conducted in one of the hospitals located in East Coast Malaysia. The presence of phlebitis was assessed using the visual infusion phlebitis score checklist. The patients were followed until PIVC removal. A total of 321 data were collected among patients who received a new PIVC in the medical, gynecology, and orthopedic wards. The incidence of phlebitis was 36.1% (n = 116), and 96.6% of which were grade II. Patients aged 60 years (51.5%), men (42.2%), no known phlebitis history (47.4%), and with chronic disease record (46.8%) were determined as the highest percentage with phlebitis. This study demonstrated that age, gender, and chronic diseases were risk factors of developing phlebitis.  Abstrak Karakteristik Pasien yang Berhubungan dengan Flebitis di Rumah Sakit Pantai Timur Semenanjung Malayía. Di antara pasien yang dirawat di rumah sakit, penyisipan kateter intravena perifer (PIVC) umum untuk pengobatan. Namun, prosedur ini seringkali gagal sebelum terapi selesai karena beberapa komplikasi. Salah satu komplikasi yang terjadi adalah flebitis. Oleh karena itu, penelitian ini bertujuan untuk menentukan kejadian dan faktor-faktor terkait flebitis di antara pasien dengan PIVC. Sebuah studi kohort prospektif dilakukan di salah satu rumah sakit yang berlokasi di Pantai Timur Malaysia. Kejadian flebitis dinilai menggunakan daftar periksa skor Visual Infusion Phlebitis (VIP). Para pasien ditindaklanjuti sampai pengangkatan PIVC. Terdapat 321 data yang dikumpulkan di antara pasien yang menerima PIVC baru di bangsal medis, ginekologi, dan ortopedi. Insiden flebitis ditemukan 36,1% (n = 116), 96,6% di antaranya adalah grade II. Pasien berusia 60 tahun (51,5%), pria (42,2%), pasien tidak memiliki riwayat flebitis (47,4%) dan pasien dengan catatan penyakit kronis (46,8%) tercatat sebagai persentase tertinggi dengan flebitis. Studi ini menunjukkan bahwa usia, jenis kelamin, dan pasien dengan penyakit kronis kemungkinan besar mengalami flebitis.Kata Kunci: flebitis, kateter intravena peripheral, pasien dewasa. 

2021 ◽  
Vol 24 (1) ◽  
pp. 25-31
Author(s):  
Azlina Daud ◽  
Fatimah Mohamad

The insertion of peripheral intravenous catheters (PIVCs) is common for treatment among hospitalized patients. However, this procedure usually fails before the end of therapy because of several complications, including phlebitis. Therefore, this study aimed to determine the incidence and associated factors of phlebitis among patients with PIVC. A prospective cohort study was conducted in one of the hospitals located in East Coast Malaysia. The presence of phlebitis was assessed using the visual infusion phlebitis score checklist. The patients were followed until PIVC removal. A total of 321 data were collected among patients who received a new PIVC in the medical, gynecology, and orthopedic wards. The incidence of phlebitis was 36.1% (n= 116), and 96.6% of which were grade II. Patients aged 60 years (51.5%), men (42.2%), no known phlebitis history (47.4%), and with chronic disease record (46.8%) were determined as the highest percentage with phlebitis. This study demonstrated that age, gender, and chronic diseases were risk factors of developing phlebitis. Abstrak Karakteristik Pasien yang Berhubungan dengan Flebitis di Rumah Sakit Pantai Timur Semenanjung Malayía. Di antara pasien yang dirawat di rumah sakit, penyisipan kateter intravena perifer (PIVC) umum untuk pengobatan. Namun, prosedur ini seringkali gagal sebelum terapi selesai karena beberapa komplikasi. Salah satu komplikasi yang terjadi adalah flebitis. Oleh karena itu, penelitian ini bertujuan untuk menentukan kejadian dan faktor-faktor terkait flebitis di antara pasien dengan PIVC. Sebuah studi kohort prospektif dilakukan di salah satu rumah sakit yang berlokasi di Pantai Timur Malaysia. Kejadian flebitis dinilai menggunakan daftar periksa skor Visual Infusion Phlebitis (VIP). Para pasien ditindaklanjuti sampai pengangkatan PIVC. Terdapat 321 data yang dikumpulkan di antara pasien yang menerima PIVC baru di bangsal medis, ginekologi, dan ortopedi. Insiden flebitis ditemukan 36,1% (n= 116), 96,6% di antaranya adalah grade II. Pasien berusia 60 tahun (51,5%), pria (42,2%), pasien tidak memiliki riwayat flebitis (47,4%) dan pasien dengan catatan penyakit kronis (46,8%) tercatat sebagai persentase tertinggi dengan flebitis. Studi ini menunjukkan bahwa usia, jenis kelamin, dan pasien dengan penyakit kronis kemungkinan besar mengalami flebitis. Kata Kunci: flebitis, kateter intravena peripheral, pasien dewasa


2006 ◽  
Vol 85 (1) ◽  
pp. 85-88 ◽  
Author(s):  
W.H. van Palenstein Helderman ◽  
W. Soe ◽  
M.A. van ’t Hof

A retrospective cohort study on ECC and associated factors was conducted among mothers with 25- to 30-month-old infants in a community where prolonged breastfeeding was common practice. All infants who consumed sugary supplementary food or rice that was pre-chewed by the mother, or who fell asleep with the breast nipple in their mouths, had ECC. Infants without those habits, and who were breastfed up to 12 months, had no ECC. Breastfeeding during the day beyond the age of 12 months was not associated with ECC, but infants who were breastfed at night > 2 times had an OR for ECC of 35 (CI 6-186), and those who were exposed to > 15 min per nocturnal feeding had an OR for ECC of 100 (CI 10-995). The present study indicates that, in this population, besides the consumption of sugars and pre-chewed rice, nocturnal breastfeeding after the age of 12 months poses a risk of developing ECC.


2020 ◽  
Vol 68 (4) ◽  
pp. 828-837
Author(s):  
Mª Reyes Carrión-Camacho ◽  
José Manuel Molina-Doñoro ◽  
José Rafael González-López

The objective of this study was to identify the complications and associated factors presented by patients after pacemaker implantation, according to a regimen of antithrombotic therapy or without it. This is an analytical observational study on a prospective cohort of 310 consecutive patients with a permanent pacemaker implanted, included from January 1 to December 31, 2014 from 1 single center. The follow-up was conducted on 310 patients for 6 months. 239 patients (77%) received antithrombotic therapy at the time of the pacemaker implantation. 20.8% of complications are presented in patients without anticoagulant therapy, 80.8% of them being minor ones. In the case of patients with anticoagulant therapy, 30.3% of the complications are major ones. Factors associated with major complications were contusion (OR 2; 95% CI 1 to 3.8; p=0.049), and minor complications, arm immobilization >24 hours (p=<0.001) and contusion (p=0.002). This study found an increase in the overall risk and complications that can occur when implanting a permanent pacemaker in patients with antithrombotic therapy based on the time of immobilization and contusions after the implantation.


2019 ◽  
Vol 47 (11) ◽  
pp. 5465-5474 ◽  
Author(s):  
Pan Liu ◽  
Yaxin Zhang ◽  
Lina Ma

Telomeres and telomerase play important roles in the occurrence and development of hypertension. This review was performed to clarify the factors that influence telomere length and telomerase activity in older patients and elucidate the association of these factors with hypertension. A PubMed search and critical review of studies assessing the risk factors underlying the association of hypertension with telomere length and telomerase activity was performed. Telomere length and telomerase activity were found to be associated with hypertension. The factors that influence telomere length and telomerase activity in older patients with hypertension include genetics, demographics, social and environmental factors, chronic disease, psychological factors, and antihypertensive drug treatment. A better understanding of the molecular mechanisms underlying the association of hypertension with telomere length and telomerase activity may help to reduce the incidence of hypertension.


Antibiotics ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 117
Author(s):  
Sharifo Ali Elmi ◽  
David Simons ◽  
Linzy Elton ◽  
Najmul Haider ◽  
Muzamil Mahdi Abdel Hamid ◽  
...  

Antimicrobial resistance is of concern to global health security worldwide. We aimed to identify the prevalence, resistance patterns, and risk factors associated with Escherichia coli (E. coli) resistance from poultry farms in Kelantan, Terengganu, and Pahang states of east coast peninsular Malaysia. Between 8 February 2019 and 23 February 2020, a total of 371 samples (cloacal swabs = 259; faecal = 84; Sewage = 14, Tap water = 14) were collected. Characteristics of the sampled farms including management type, biosecurity, and history of disease were obtained using semi-structured questionnaire. Presumptive E. coli isolates were identified based on colony morphology with subsequent biochemical and PCR confirmation. Susceptibility of isolates was tested against a panel of 12 antimicrobials and interpreted alongside risk factor data obtained from the surveys. We isolated 717 E. coli samples from poultry and environmental samples. Our findings revealed that cloacal (17.8%, 46/259), faecal (22.6%, 19/84), sewage (14.3%, 2/14) and tap water (7.1%, 1/14) were significantly (p < 0.003) resistant to at least three classes of antimicrobials. Resistance to tetracycline class were predominantly observed in faecal samples (69%, 58/84), followed by cloacal (64.1%, 166/259), sewage (35.7%, 5/14), and tap water (7.1%, 1/84), respectively. Sewage water (OR = 7.22, 95% CI = 0.95–151.21) had significant association with antimicrobial resistance (AMR) acquisition. Multivariate regression analysis identified that the risk factors including sewage samples (OR = 7.43, 95% CI = 0.96–156.87) and farm size are leading drivers of E. coli antimicrobial resistance in the participating states of east coast peninsular Malaysia. We observed that the resistance patterns of E. coli isolates against 12 panel antimicrobials are generally similar in all selected states of east coast peninsular Malaysia. The highest prevalence of resistance was recorded in tetracycline (91.2%), oxytetracycline (89.1%), sulfamethoxazole/trimethoprim (73.1%), doxycycline (63%), and sulfamethoxazole (63%). A close association between different risk factors and the high prevalence of antimicrobial-resistant E. coli strains reflects increased exposure to resistant bacteria and suggests a concern over rising misuse of veterinary antimicrobials that may contribute to the future threat of emergence of multidrug-resistant pathogen isolates. Public health interventions to limit antimicrobial resistance need to be tailored to local poultry farm practices that affect bacterial transmission.


2020 ◽  
Author(s):  
Clifford Silver Tarimo ◽  
Jian Wu ◽  
Joseph Obure ◽  
Michael Johnson Mahande

Abstract Background Labor induction (IOL) refers to an obstetric intervention which include artificial stimulation of uterine contraction aiming at vaginal delivery of a fetus before the onset of spontaneous labor. Despite undisputed importance of this intervention in improving pregnancy outcomes, data on its utilization and outcomes in Tanzania is limited. The aim of this study was to determine the prevalence, associated factors and outcomes for labor induction among women who were attended at a tertiary hospital in north-Tanzania. Methods We designed a retrospective cohort study and analyzed 53338 deliveries at the Kilimanjaro Christian Medical Centre (KCMC) between the year 2000 to 2015. We enrolled singleton deliveries with vertex presentation and excluded observations with missing information on induction status. Relative risk and 95% Confidence Interval for risk factors and outcomes of labor induction were estimated using log-binomial regression models. Robust variance estimation was used to account for repeated deliveries from the same subject. Results 53,338 deliveries were analyzed. Prevalence of labor induction was 21.63%. Independent risk factors for labor induction were; postdates (RR = 1.21; 95% CI: 1.15–1.28), fetal macrosomia (RR = 1.27; 95% CI: 1.18–1.36) and obesity (RR = 1.12; 95% CI: 1.06–1.18). Labor induction was associated with an increased risk of uterine rapture (RR = 1.84; 95% CI: 1.62–2.09) and low (< 7) Apgar score (RR = 1.27; 95% CI: 1.17–1.37). Labor induction offered protective effect against cesarean delivery (RR = 0.56; 95% CI: 0.53–0.58) and admission to neonatal intensive care unit (RR = 0.94; 95% CI: 0.89–0.99). Conclusion Efforts aimed at achieving the health-related sustainable development goals should focus on increasing access to effective interventions as well as improving quality of health care while being cautioned on likelihood of adverse maternal and fetal outcomes.


2021 ◽  
Vol 19 (01) ◽  
pp. 177-185
Author(s):  
NURUL ANISAH JAAFAR ◽  
NOR AZLIN MOHD NORDIN ◽  
SYED MOHAMED ALJUNID

Kanak – kanak kurang upaya memerlukan pemulihan yang komprehensif dan berterusan. Pusat Pemulihan dalm Komuniti (PDK) telah dibina untuk memenuhi keperluan ini dan telah memberi manfaat kepada semua peringkat umur dalam kalangan masyarakat bandar dan luar bandar. Di Malaysia, kerajaan telah membiayai sebahagian besar pemulihan kanak – kanak kurang upaya di PDK. Walau bagaimanapun, setakat ini kajian mengenai keberhasilan PDK untuk kanak – kanak kurang upaya di negara ini amat terhad. Kajian ini bertujuan menentukan keberhasilan program pemulihan serta mengenalpasti faktor-faktor yang berkaitan dengannya dalam kalangan kanak-kanak kurang upaya di PDK. Sejumlah 220 orang kanak – kanak kurang upaya berumur 4 hingga 18 tahun dan 220 penjaga daripada 29 pusat PDK di Pahang, Terengganu dan Kelantan telah menyertai kajian. Keberhasilan program ditentukan dari aspek perubahan tahap keupayaan dalam aktiviti harian menggunakan Indeks Barthel selepas 6 bulan menjalani PDK. Faktor berkait yang dikaji ialah umur, jenis kurang upaya, skor asas Indeks Barthel, jenis program yang diikuti dan kekerapan kehadiran ke sesi terapi. Hasil kajian menunjukkan terdapat peningkatan kecil dalam Indeks Barthel, min perubahan ± SP bersamaan 0.90 ± 4.54 (p=0.003) selepas pemulihan. Tahap kehadiran ke sesi terapi adalah rendah iaitu < 50% menunjukkan kehadiran tiga perempat atau penuh dari keseluruhan sesi terapi yang ditawarkan. Semua faktor yang dikaji didapati tidak mempunyai kaitan dengan perubahan skor Indeks Barthel (p>0.05) kecuali jenis program yang diikuti (r=0.14, p=0.03). Sebagai kesimpulan, keberhasilan pemulihan yang diperolehi melalui PDK amat kecil bagi tempoh latihan yang dijalani. Implementasi program perlu dinilai dan ditambahbaik bagi meningkatkan manfaatnya terhadap kanak-kanak kurang upaya.


Author(s):  
Pranjal Rai ◽  
Vinaykumar Thati ◽  
Geeta Ghag ◽  
Vipul Nandu

<p class="abstract"><strong>Background:</strong> Intravenous catheters cause endothelial damage and trauma, which can predispose to venous thrombosis. Peripheral vein infusion thrombophlebitis occurs in 25- 35% of hospitalized patients with intravenous catheters and has both patient-related implications (e.g., sepsis) and economic consequences (e.g., extra nursing time). This study is designed to address this issue, by assessing the potential risk factors in those who have developed phlebitis, and deriving conclusions based on the same.</p><p class="abstract"><strong>Methods:</strong> A total of 830 patients were observed over a period of 2 months. All details of the patient were collected. Thrombophlebitis was graded using Visual Infusion Phlebitis Score. Each case was compared with a matching control.  </p><p class="abstract"><strong>Results:</strong> 53 of 830 patients observed, developed thrombophlebitis giving an incidence of 6.4%. 92.5% had IV cannulation flushed after insertion. IV cannula had to be changed at least 2 times during the hospital stay. All had an average IV cannulation for 5 days. All had insertion of same size cannula (20G). Level 1 Phlebitis was identified in 64.15% patients, level 2 Phlebitis in 33.96% patients and Level 3 Phlebitis was seen 1.88% patients.</p><p class="abstract"><strong>Conclusions:</strong> Significant association was noted between the number of times the catheter was changed since admission and administration of Potassium chloride and Certain Medications such as Piperacillin through the cannula.</p>


2005 ◽  
Vol 1 (1) ◽  
pp. 166-167
Author(s):  
M.S. Farini ◽  
A. Azlina ◽  
I. Rushdan ◽  
M. Manoharan ◽  
R.B. Zain ◽  
...  

Pathogens ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 1160
Author(s):  
Abdinasir Yusuf Osman ◽  
Sharifo Ali Elmi ◽  
David Simons ◽  
Linzy Elton ◽  
Najmul Haider ◽  
...  

The burden of antimicrobial use in agricultural settings is one of the greatest challenges facing global health and food security in the modern era. Malaysian poultry operations are a relevant but understudied component of epidemiology of antimicrobial resistance. We aimed to identify the prevalence, resistance patterns, and risk factors associated with Salmonella isolates from poultry farms in three states of East Coast Peninsular Malaysia. Between 8 February 2019 and 23 February 2020, a total of 371 samples (cloacal swabs = 259; faecal = 84; Sewage = 14, Tap water = 14) was collected from poultry operations. Characteristics of the sampled farms and associated risk factors were obtained using semi-structured questionnaires. Presumptive Salmonella spp. isolates were identified based on colony morphology with subsequent biochemical and PCR confirmation. Susceptibility of isolates was tested against a panel of 12 antimicrobials using disk diffusion method. Our findings revealed that the proportion of Salmonella spp.-positive isolates across sample source were as following: cloacal swab (46.3%, 120/259); faecal (59.5%, 50/84); in tap water (14.3%, 2/14); and in sewage sample (35.7%, 5/14). Isolates from faecal (15.5%, 13/84), cloacal (1.2%, 3/259), and sewage (7.1%, 1/14) samples were significantly resistant to at least five classes of antimicrobials. Resistance to Sulfonamides class (52%, 92/177) was predominantly observed followed by tetracycline (39.5%, 70/177) and aminoglycosides (35.6%, 63/177). Multivariate regression analysis identified intensive management system (OR = 1.55, 95% CI = 1.00–2.40) as a leading driver of antimicrobial resistance (AMR) acquisition. A prevalence of resistance to common antimicrobials was recorded for sulfamethoxazole (33.9%), tetracycline (39.5%), and trimethoprim-sulphamethoxazole (37.9%). A close association between different risk factors and the prevalence of AMR of Salmonella strains suggests a concern over rising misuse of veterinary antimicrobials that may contribute to the emergence and evolution of multidrug-resistant pathogen isolates. One Health approach is recommended to achieve a positive health outcome for all species.


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