scholarly journals PHYTOCHEMICAL AND PHARMACOLOGICAL ACTIVITIES OF JUSTICIA PROCUMBENS L.: A REVIEW

2020 ◽  
Vol 11 (5) ◽  
pp. 190-193
Author(s):  
Amritha C K ◽  
Suma C ◽  
Ananya V M ◽  
Thushara P V ◽  
Deepak V S
Keyword(s):  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Active Compounds ◽  
Traditional Uses ◽  
Current Review ◽  
Snake Bites ◽  
Anti Inflammatory ◽  
Water Willow ◽  
Anti Hiv

Justicia procumbens L. is usually known as water willow which belongs to family Acanthaceae growing widely in southern regions of China, Japan, Vietnam, India and Australia. It is one of the important herbal being used in Ayurvedic system of medicine. The plant contains various active compounds like arylnaphthalide and diarylbutane lignans, glycosides, flavonoids. Few pharmacological properties including anti-inflammatory, anti-arthritic, anti-arrhythmic, anti-asthmatic, anti-proliferative, anti-allergic, antibacterial, cytotoxic and anti-HIV activities activity have been reported for this plant. Conventionally, it is used for the treatment of fever, inflammation, cold, cough, asthma, cancer, snake bites etc. The current review is created with an intended to focus on the numerous ethnobotanical and traditional uses as well as the phytochemical and pharmacological report on Justicia procumbens.

scholarly journals Ethnomedicinal, Pharmacological Properties and Phytochemistry of Sida spinosa Linn. A mini review

2018 ◽  
Vol 7 (1) ◽  
pp. 88-91
Author(s):  
Ajeet Singh ◽  
◽  
Navneet ◽  
Keyword(s):  
Genitourinary Tract ◽  
Pharmacological Properties ◽  
Traditional Uses ◽  
Comprehensive Survey ◽  
Anti Inflammatory ◽  
Sida Spinosa ◽  
Analgesic Activities ◽  
Anti Hiv

The comprehensive survey information as provided in this review on Sida spinosa Linn traditional uses, ethanobotanical aspects, phytochemistry and pharmacology. The plant has a variety of traditional uses. Leaves are reported to possess demulcent, refrigerant properties, and are useful in cases of gonorrhoea, gleet and scalding urine. They are bruised in water and the filtrate is administered. Root is used as a tonic and diaphoretic and is given in mild cases of debility and fever. A decoction of it is said to be given as a demulcent in irritability of bladder and in gonorrhoea. Decoction given as a demulcent in irritability of bladder and genitourinary tract. Leaves are used as demulcent and refrigerant; used for scalding urine. Sida spinosa possesses various traditional and pharmacological properties includes antibacterial, antifungal, anti-helmintic, anti-fertility, antidiabetic, anti-inflammatory, antioxidant, anti-HIV, anti-arthritic, cytoprotective, hepatoprotective, anti-diarrhoeal and analgesic activities of Sida spinosa

scholarly journals A PHARMACOGNOSTIC AND PHARMACOLOGICAL REVIEW ON CHROMOLAENA ODORATA (SIAM WEED)

2018 ◽  
Vol 11 (10) ◽  
pp. 34
Author(s):  
Vanita Kanase ◽  
Sana Shaikh
Keyword(s):  
Skin Diseases ◽  
The United States ◽  
Pharmacological Properties ◽  
Chromolaena Odorata ◽  
Pharmacological Activities ◽  
Tropical Asia ◽  
Current Review ◽  
Young Leaves ◽  
The Caribbean ◽  
Important Medicinal Plant

Chromolaena odorata is commonly known as Siam weed which belongs to sunflower family Asteraceae. C. odorata is an important medicinal plant which can be easily found in tropical Asia, West Africa, and parts of Australia. It is native to the America, and found in Florida and Texas in the United States, throughout Mexico and the Caribbean to South America. The medicinal usage of C. odorata has been reported in the traditional systems of medicine such as Ayurveda, Siddha, and Unani. It has wide variety of ethanomedicinal and pharmacological properties. The young leaves are crushed, and the resulting liquid can be used to treat skin wounds. The leaves extract is used by the kani tribals of Kouthalai in Tirunelveli hills to cure skin diseases, poison bites, wounds, and rheumatism. Following various folk claims for the ailment of various diseases, efforts have been made by the researchers to verify the efficacy of this weed through scientific biological screenings. A study of the literature revealed some notable pharmacological activities of the shrub such as anthelmintic, antimalarial, analgesic, anti-inflammatory, antipyretic, antispasmodic, antioxidant, antigonorrheal, antimycobacterial, insecticidal, fungicidal, wound healing, diuretic, blood coagulation, and antibacterial. The current review is created with an intent to focus on the numerous ethnobotanical and traditional uses as well as the phytochemical and pharmacological reports on C. odorata.

scholarly journals Natural Products, Traditional Uses and Pharmacological Activities of the Genus Biebersteinia (Biebersteiniaceae)

Plants ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 595 ◽  
Author(s):  
Benyin Zhang ◽  
Xiaona Jin ◽  
Hengxia Yin ◽  
Dejun Zhang ◽  
Huakun Zhou ◽  
...  
Keyword(s):  
Natural Products ◽  
Molecular Mechanisms ◽  
Chemical Properties ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Drug Discovery And Development ◽  
Chemical Structures ◽  
Traditional Uses ◽  
Novel Drugs ◽  
Major Chemical

Medicinal plants have been known as a rich source of natural products (NPs). Due to their diverse chemical structures and remarkable pharmacological activities, NPs are regarded as important repertoires for drug discovery and development. Biebersteinia plant species belong to the Biebersteiniaceae family, and have been used in folk medicines in China and Iran for ages. However, the chemical properties, bioactivities and modes of action of the NPs produced by medicinal Biebersteinia species are poorly understood despite the fact that there are only four known Biebersteinia species worldwide. Here, we reviewed the chemical classifications and diversity of the various NPs found in the four known Biebersteinia species. We found that the major chemical categories in these plants include flavonoids, alkaloids, phenylpropanoids, terpenoids, essential oils and fatty acids. We also discussed the anti-inflammatory, analgesic, antibacterial, antioxidant, antihypertensive and hypoglycemic effects of the four Biebersteinia species. We believe that the present review will facilitate the exploration of traditional uses and pharmacological properties of Biebersteinia species, extraction of the NPs and elucidation of their molecular mechanisms, as well as the development of novel drugs based on the reported properties and mode-of-action.

scholarly journals Ethanobotanical, phytochemical and pharmacological properties of Zizyphus nummularia (Burm. F.): A Review

2018 ◽  
Vol 10 (3) ◽  
pp. 137
Author(s):  
Babita Aggarwal ◽  
Pankaj Sharma ◽  
HS Lamba
Keyword(s):  
Mental Retardation ◽  
Folk Medicine ◽  
Present Review ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Anti Inflammatory

<p><em>Zizyphus nummularia</em> (Burm. F.), Family: Rhamnaceae, is widely distributed in dry regions of India. It is a bushy weed used as folk medicine. The plant is valued for its nutritional edible fruits. Traditionally, it is used in mental retardation, fever, diarrhea, dysentery. The plant has been evaluated for various pharmacological activities such as anti-inflammatory, anthelmintic, antibacterial, antifertility activity. Present review discusses phytochemistry and pharmacological aspects of the drug.</p>

scholarly journals Phytochemistry, Traditional Uses and Pharmacological Properties of the Genus Opopanax W. D. J. Koch: A Mini-Review

2020 ◽  
Vol 26 (2) ◽  
pp. 99-106
Author(s):  
Alev Önder ◽  
Lutfun Nahar ◽  
Sushmita Nath ◽  
Satyajit D. Sarker
Keyword(s):  
Traditional Medicine ◽  
Mediterranean Region ◽  
Antimicrobial Activities ◽  
Evidence Based ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Traditional Uses ◽  
Phytochemical Profile ◽  
The Mediterranean ◽  
Antioxidant And Antimicrobial Activities

The genus Opopanax W.D.J. Koch is a member of the Apiaceae family, distributed throughout the Mediterranean region and comprises only three recognized and well-defined species, O. chironium (L.) W.D.J. Koch, O. hispidus (Friv.) Griseb. and O. persicus Boiss. The species of this genus with yellow flowers are well-known in traditional medicine and consumed as food. This review critically appraises published literature on the phytochemistry, traditional usages, and pharmacological activities of the genus Opopanax. In addition, it provides evidence to suggest that the plants from this genus have potential phytotherapeutic applications. Previous phytochemical and bioactivity studies revealed that the genus Opopanax predominantly produces coumarins, diterpenes, phenolics, and phthalides, and possesses various biological and pharmacological properties, including anticancer, antioxidant and antimicrobial activities. The phytochemical profile and pharmacological activities of the genus Opopanax could be useful for further study and might find additional medicinal applications in evidence-based phytotherapy

Benzimidazole: A Milestone in the Field of Medicinal Chemistry

2020 ◽  
Vol 20 (7) ◽  
pp. 532-565 ◽  
Author(s):  
Mahesh S. Vasava ◽  
Manoj N. Bhoi ◽  
Sanjay K. Rathwa ◽  
Divya J. Jethava ◽  
Prachi T. Acharya ◽  
...  
Keyword(s):  
Medicinal Chemistry ◽  
Benzimidazole Derivatives ◽  
Drug Candidate ◽  
Pharmacological Activities ◽  
Drug Candidates ◽  
The Future ◽  
Anti Inflammatory ◽  
Anti Fungal ◽  
Derivatives Of ◽  
Anti Hiv

In the last 2-3 decades, the broad research in the application of benzimidazole derivatives made it important for mankind. Many scientists have worked on benzimidazole derivatives and they found that this compound has a diverse role in the field of medicinal chemistry. Few benzimidazole derivatives are currently in the market as a drug candidate against various diseases. Moreover, the benzimidazole derivatives exhibit pharmacological activities such as anti-tuberculosis, anti-malarial, antihistamine, antimicrobial, antiviral, antidiabetic, anticancer, anti-fungal, anti-inflammatory, analgesic, anti-HIV, etc. In this review, we have summarized various derivatives of benzimidazole which have been prepared by many researchers to understand the chemistry as well as diverse pharmacological activities. These findings may lead the scientists who are working in the field of medicinal chemistry to the development of benzimidazole based drug candidates in the future.

Benzofuran: A Key Heterocycle - Ring Closure And Beyond

2020 ◽  
Vol 17 (3) ◽  
pp. 224-276
Author(s):  
Andiappan Lavanya ◽  
Kilambi Narasimhan ◽  
Vediappen Padmini
Keyword(s):  
Biological Activities ◽  
Extraction Process ◽  
Ring Closure ◽  
Pharmacological Activities ◽  
Naturally Occurring ◽  
Synthetic Materials ◽  
Privileged Scaffold ◽  
Medicinal Properties ◽  
Anti Inflammatory ◽  
Anti Hiv

: The benzofuranyl motif present in compounds exhibits various medicinal properties and non-drug applications. These derivatives are naturally occurring compounds or synthetic materials, which cover a broad spectrum of pharmacological activities like anti-inflammatory, anti-diabetic, anti- depressant, anti-HIV, anti-microbial, anti-proliferative, anti-convulsant, cytotoxic, analgesic, etc. Few of the commercially interesting compounds from this class are, ailanthoidol (anti-inflammatory), amiodarone, dronedarone, celivarone (anti-arrhythmic), bufuralol (muscular airways relaxant), morphine, 5-(2-aminopropyl)benzofuran; 5-APB, 6-(2-aminopropyl)benzofuran; 6-APB (CNS), rifampicin (antibiotic), etc., whereas, some of the non-drug applications are in perfumery industry (bergapten) and as tannin activators in sunscreen preparations (psoralen, 8-methoxypsoralen, and angelicin). Considering these interesting biological activities and commercial utilities, a review on the synthetic aspects of this privileged scaffold was attempted. For the benefit of natural product-based drug discovery, available sources of these derivatives, extraction process and reported biological activities have also been outlined in this review.

scholarly journals HING (Ferula foetida Regel): A potent Unani Herb with its descriptive parameters of pharmacognosy and pharmacology: A Review

2020 ◽  
Vol 10 (5) ◽  
pp. 362-367
Author(s):  
Rasikh Javaid ◽  
Ghazala Javed ◽  
Raheela Javaid ◽  
, Anju ◽  
Farah Ahmed ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Central Asia ◽  
Present Review ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Unani Medicine ◽  
Traditional Uses ◽  
Pharmacological Studies ◽  
Botanical Description ◽  
Biological And Pharmacological Activities

Hing (Family- Umbelliferae) or asafoetida is the latex obtained from living rootstocks or taproots of several species of Ferula, e.g. F. alliacea Boiss, F. rubricaulis Boiss, F. assafoetida Linn and F. narthex Boiss found in central Asia. Asafoetida occurs in three forms, viz Tears, Mass and Paste. Hing has shown diverse biological and pharmacological activities. It has been used in Unani Medicine (Tibb-e-Unani) and other Traditional Systems of Medicine from time immemorial and it is described as diuretic, anti-diabetic, emmenagogue etc. The present review highlights the botanical description, traditional uses, pharmacognositcal features, pharmacological properties and pharmacological studies conducted on this Medicinal plant used in Unani system of medicine. Keywords: Hing; Ferula foetida; Unani Medicine; Traditional Uses; Pharmacological Properties

A Mini-Review on Pharmacological Importance of Benzothiazole Scaffold

2020 ◽  
Vol 17 ◽  
Author(s):  
Mohammad Asif ◽  
Mohd. Imran
Keyword(s):  
Heterocyclic Compounds ◽  
Biologically Active ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Structural Alterations ◽  
Benzothiazole Derivatives ◽  
Drug Molecules ◽  
Anti Inflammatory ◽  
Almost All

: Heterocyclic compounds are important because they have almost all types of pharmacological properties. Due to these properties of heterocyclic compounds, they attracted the researchers for the development of more effective newer drug molecules. In this review, we are focused on benzothiazole and its derivatives, which are used for the synthesis of various biologically active molecules. Benzothiazole derivatives have been possessed the various type of pharmacological activities like antimicrobial, anti-inflammatory, analgesic, anticonvulsant, antiviral, anthelmintic, antioxidant, anticancer, and other anticipated activities. Hence, structural alterations have resulted in different benzothiazole derivatives that illustrated a wide variety of pharmacological activities.

scholarly journals Tabebuia impetiginosa: A Comprehensive Review on Traditional Uses, Phytochemistry, and Immunopharmacological Properties

Molecules ◽  
2020 ◽  
Vol 25 (18) ◽  
pp. 4294 ◽  
Author(s):  
Jianmei Zhang ◽  
Stephanie Triseptya Hunto ◽  
Yoonyong Yang ◽  
Jongsung Lee ◽  
Jae Youl Cho
Keyword(s):  
Skin Diseases ◽  
Fungal Infections ◽  
Scientific Evidence ◽  
Inflammatory Activity ◽  
Future Research ◽  
Pharmacological Activities ◽  
Traditional Uses ◽  
New Strategy ◽  
Anti Inflammatory ◽  
Underlying Mechanisms

Tabebuia impetiginosa, a plant native to the Amazon rainforest and other parts of Latin America, is traditionally used for treating fever, malaria, bacterial and fungal infections, and skin diseases. Additionally, several categories of phytochemicals and extracts isolated from T. impetiginosa have been studied via various models and displayed pharmacological activities. This review aims to uncover and summarize the research concerning T. impetiginosa, particularly its traditional uses, phytochemistry, and immunopharmacological activity, as well as to provide guidance for future research. A comprehensive search of the published literature was conducted to locate original publications pertaining to T. impetiginosa up to June 2020. The main inquiry used the following keywords in various combinations in titles and abstracts: T. impetiginosa, Taheebo, traditional uses, phytochemistry, immunopharmacological, anti-inflammatory activity. Immunopharmacological activity described in this paper includes its anti-inflammatory, anti-allergic, anti-autoimmune, and anti-cancer properties. Particularly, T. impetiginosa has a strong effect on anti-inflammatory activity. This paper also describes the target pathway underlying how T. impetiginosa inhibits the inflammatory response. The need for further investigation to identify other pharmacological activities as well as the exact target proteins of T. impetiginosa was also highlighted. T. impetiginosa may provide a new strategy for prevention and treatment of many immunological disorders that foster extensive research to identify potential anti-inflammatory and immunomodulatory compounds and fractions as well as to explore the underlying mechanisms of this herb. Further scientific evidence is required for clinical trials on its immunopharmacological effects and safety.

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