scholarly journals Multi-functions of Protaetia brevitarsis surensis (PBS, Larvae for Food) Reported in South Korea

2021 ◽  
pp. 1-8
Author(s):  
Mi-So Cho ◽  
Young-Son Cho
Keyword(s):  
South Korea ◽  
Common Sense ◽  
Inflammatory Disease ◽  
Extraction Methods ◽  
Therapeutic Effects ◽  
Vegetable Food ◽  
Adults And Children ◽  
Folk Remedies ◽  
Prevention Of Breast Cancer ◽  
Physical Constitution

Nowadays most people in advanced countries endangered under adult diseases such as hypertension, diabetes, hyperlipidemia, inflammatory disease, human oxidation, and liver-related diseases. In South Korea also very serious situation for the adults and children by the changing from vegetable food to animal food and changed labor pattern from physical labor to mental labor. We aim to review Protaetia brevitarsis surensis (PBS)’s beneficial multi-functions on human with research reports and verification of well-known common sense in South Korea, which was commonly known as medicinally very effective in liver related diseases. PBS larvae known as cold body characteristics, so, it more effective to Yang-in(Oriental physical constitution classification method: Warm body which Jinseng, Panax ginseng, not available people) than Um-in(Cool body- Jinseng available people). The functional effects mostly known effective on liver related diseases mainly by oriental clinic and as folk remedies. However, nowadays PBS larvae’s folk remedies and other multi-functions scientifically researched and that results verified by many papers such as whitening of skin therapeutic effects, prevention of breast cancer, inflammatory disease, human oxidation, and liver-related diseases. For the increasing of medicinal effects, advanced fermentation and ethanol extraction methods will be very useful compared to non-fermentation of PBS larvae and water extraction. So, we concluded that PBS could diminish or decreasing the adult diseases and it will be very useful food and medicinal materials simultaneously for the human food and medicine by the advanced extraction methods.

Placebos and Movies: What Do They Have in Common?

2021 ◽  
pp. 096372142110038
Author(s):  
Fabrizio Benedetti
Keyword(s):  
Everyday Life ◽  
Common Sense ◽  
Placebo Effect ◽  
Psychological Factors ◽  
General Framework ◽  
Physiological Responses ◽  
Therapeutic Effects ◽  
Physiological Effects ◽  
Placebo Effects ◽  
What Matters

Placebos are fake therapies that can induce real therapeutic effects, called placebo effects. It goes without saying that what matters for inducing a placebo effect is not so much the fake treatment itself, but rather the therapeutic ritual that is carried out, which is capable of triggering psychobiological mechanisms in the patient’s brain. Both laypersons and scientists often accept the phenomenon of the placebo effect with reluctance, as fiction-induced clinical improvements are at odds with common sense. However, it should be emphasized that placebo effects are not surprising after all if one considers that fiction-induced physiological effects occur in everyday life. Movies provide one of the best examples of how fictitious reality can induce psychological and physiological responses, such as fear, love, and tears. In the same way that a horror movie induces fear-related physiological responses, even though the viewer knows everything is fake, so the sight of a syringe may trigger the release of pain-relieving chemicals in the patient’s brain, even if the patient knows there is a fake painkiller inside. From this perspective, placebos can be better conceptualized as rituals, actions, and fictions within a more general framework that emphasizes the power of psychological factors in everyday life, including the healing context.

scholarly journals Effects of different factors influencing the essential oil properties of Thymus vulgaris L.

2016 ◽  
Vol 3 (3) ◽  
pp. 312 ◽  
Author(s):  
Zsuzsanna Pluhár ◽  
Dóra Szabó ◽  
Szilvia Sárosi
Keyword(s):  
Essential Oil ◽  
Extraction Methods ◽  
Storage Conditions ◽  
Thymus Vulgaris ◽  
Therapeutic Effects ◽  
Aromatic Plant ◽  
Active Constituent ◽  
Factors Influencing ◽  
Scientific Results ◽  
Growing Conditions

Thymus vulgaris L. is a well-know medicinal and aromatic plant native to the Mediterranean region. The essential oil is considered as the main active constituent, being responsible for its typical odour and taste as well as for several therapeutic effects. Our aim was to demonstrate the most important factors influencing the quality and quantity parameters of thyme oil by summarizing the available literature data and our own scientific results. Genetic background, climatic and growing conditions, techniques of primary processing, storage conditions as well as different extraction methods have proven effects on the essential oil properties and, as a consequence, on its biological activity, either.

“Of course we’ll like it, we’re kids!”: interrogating childhood and parenting through children’s food

2020 ◽  
Vol 9 (1) ◽  
pp. 75-90
Author(s):  
Jennifer Patico
Keyword(s):  
Common Sense ◽  
School Community ◽  
Self Management ◽  
Ethnographic Research ◽  
Food Practices ◽  
The Usa ◽  
Adults And Children ◽  
Packaged Foods

The notion that children naturally gravitate towards sugary, starchy, packaged foods ‐ and that carefully regulating their consumption is integral to good parenting ‐ seems common sense to many in the USA and beyond. Yet such facts are not universal, but part of how childhood is being constructed in a particular moment. Drawing on in-depth ethnographic research in Atlanta among adults and children, this article examines how visions of childhood were reproduced through food practices and discourses in one school community. Here, parenting was understood to involve monitoring what children consumed, to some extent working against children’s perceived natures; at the same time, parents hesitated to overly control or limit childhood pleasures, indicating tensions in neoliberal imperatives towards self-management (to which children’s putatively unmeasured and unsophisticated tastes presented both challenges and imaginative contrast). Ultimately, the study interrogates the sociopolitical effects of such discourses about the tastes of the ‘typical child’, which can elide and obscure dynamics of class.

scholarly journals Elucidation of the active compounds and molecular mechanisms of Smilacis Chinae Rhizoma for treatment of pelvic inflammatory disease based on network pharmacology and MMGBSA-docking

2020 ◽  
Author(s):  
Yunsen Zhang ◽  
Zikuang Zhao ◽  
Wenxiang Wang ◽  
Qi Li ◽  
Huimin Chen ◽  
...  
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Signaling Pathway ◽  
Inflammatory Disease ◽  
Molecular Mechanisms ◽  
Binding Free Energy ◽  
Network Pharmacology ◽  
Therapeutic Effects ◽  
Active Ingredients ◽  
Active Compounds ◽  
Bidirectional Regulation

Abstract Background Smilacis Chinae Rhizoma (SCR) is widely used in the treatment of pelvic inflammatory disease (PID). However, its active ingredients and the mechanisms against PID remain elusive. This study aimed to clarify the active ingredients and explore their molecular mechanisms on PID. Method Network pharmacology and MMGBSA-docking exploited the active compounds and mechanisms against PID, as well as validating the binding mode of candidate targets.Results Network pharmacology revealed 32 active compounds and 718 compound-related targets mapped to 91 pathways which were clustered 7 genres (e.g., immunoregulation). C-T-P network and PPI analysis illustrated 17 PID-related targets, indicating that SCR may decrease inflammation, ameliorate fibrosis, and inhibit microorganisms via bidirectionally regulating IL-17 signaling pathway. Furthermore, active compounds were uncovered that bound to prostaglandin-endoperoxide synthase 2, matrix metalloprotein-9, lipocalin, signal transducer and activator of transcription 3, myeloperoxidase, and tumor necrosis factor. 19 active compounds (e.g., rutin (-66.43 kcal/mol), moracin M (-37.01 kcal/mol) and oxyresveratrol (-38.84 kcal/mol)) were found to show excellent binding free energy, demonstrating that H-bond, Pi electron cloud and electrostatic potential as the main binding ability to these targets. Conclusion Approach of network pharmacology and MMGBSA-docking revealed the active ingredients, such as rutin, moracin M, and oxyresveratrol, in SCR and dissected it exhibits the therapeutic effects (e.g., decrease inflammation, ameliorate fibrosis, and inhibit microorganisms) of PID by the bidirectional regulation of IL-17 signaling pathway.

scholarly journals The role of Th17 lymphocytes in pathogenesis of autoimmune arthritides

2014 ◽  
Vol 124 (1) ◽  
pp. 55-58
Author(s):  
Katarzyna Pogoda ◽  
Maria Pyszniak ◽  
Magdalena Bańka ◽  
Beata Rybojad ◽  
Jacek Tabarkiewicz
Keyword(s):  
Rheumatoid Arthritis ◽  
Juvenile Idiopathic Arthritis ◽  
Autoimmune Diseases ◽  
Inflammatory Disease ◽  
Th17 Cells ◽  
Th17 Lymphocytes ◽  
Inflammatory Phenotype ◽  
Long Time ◽  
Adults And Children

Abstract Th17 cells are newly described population of lymphoctyes, that recruits neutrophils to the site of inflammation and activate inflammatory phenotype of various tissues. They also play a pivotal role in autoimmune diseases and cancers. These cells secrete mainly different isoforms of IL-17, but also IL-21 and IL-22. Rheumatoid arthritis and juvenile idiopathic arthritis are the most common autoimmune joints’ inflammatory disease, affecting respectively adults and children. For a long time the immunopathogenesis of autoimmune diseases has been associated with Th1 lymphocytes. This hypothesis has changed after the discovery of Th17 cells, which are thought to be key mediators of autoimmune arthritides

Paraglottic Laryngitis in Association with Epiglottitis

1985 ◽  
Vol 94 (6) ◽  
pp. 618-621 ◽  
Author(s):  
Gerald B. Healy ◽  
Vincent J. Hyams ◽  
Gabriel F. Tucker
Keyword(s):  
Inflammatory Disease ◽  
Malignant Disease ◽  
Histologic Evidence ◽  
Adults And Children ◽  
Therapeutic Measures ◽  
Relationship Of ◽  
First Time ◽  
The Relationship ◽  
Paraglottic Space ◽  
Supraglottic Larynx

Infection of the supraglottic larynx is a well-recognized clinical entity in both adults and children. The anatomical relationships of the various components of the larynx have been studied extensively, especially as they relate to the spread of malignant disease. However, the relationship of these spaces and compartments in inflammatory disease has not been heretofore appreciated. This report describes for the first time histologic evidence that infection of the supraglottic larynx may spread to the paraglottic space, thus causing compromise of the glottic region. This potential carries significant implications for planning the appropriate therapeutic measures.

scholarly journals Mometasone furoate in the treatment of allergic rhinitis: a complex therapeutic effect

2021 ◽  
pp. 130-137
Author(s):  
R. S. Fassakhov ◽  
D. I. Marapov
Keyword(s):  
Allergic Rhinitis ◽  
Beneficial Effect ◽  
Nasal Congestion ◽  
Clinical Manifestations ◽  
Mometasone Furoate ◽  
Therapeutic Effects ◽  
Safety Issues ◽  
Ocular Symptoms ◽  
Systemic Bioavailability ◽  
Adults And Children

The review examines the role of mometasone furoate (NSMF) intranasal spray (Nasonex) in the treatment of allergic rhinitis (AR). There is a wide prevalence of AR both among children and adults, its adverse effect on the quality of life of patients. It is emphasized that the main means of therapy for moderate and severe course in accordance with international and Russian recommendations for the diagnosis and treatment of AR are intranasal glucocorticosteroids (INGKS). The pharmacological features of the MF molecule that underlie its efficacy and safety, including the affinity, lipophilicity and viscosity of the drug, as well as low systemic bioavailability, are discussed in detail. The therapeutic effects of NSMF in the treatment of seasonal and perennial AR, its effect on nasal symptoms are discussed in detail. The beneficial effect of NSMF therapy on nasal congestion is emphasized separately. The beneficial effect of NSMF treatment on other clinical manifestations of AR, including ocular symptoms, effects on sleep, and olfactory function, has been noted. The safety issues of NSMF use are discussed in detail, including systemic effects, such as effects on adrenal function, eye, and growth retardation in children, and local adverse effects on the nasal mucosa; there is a high profile of local and systemic safety of long-term use of NSMF in the treatment of AR in both adults and children. 

scholarly journals Comparison of DNA Extraction Methods for Metagenomic Sequencing in Anaerobic Digestion

2021 ◽  
Vol 43 (1) ◽  
pp. 43-50
Author(s):  
Juhee Shin ◽  
Youngback Kim ◽  
Seung Gu Shin
Keyword(s):  
Microbial Community ◽  
South Korea ◽  
Dna Extraction ◽  
Genomic Dna ◽  
Extraction Methods ◽  
Microbial Populations ◽  
Metagenomic Sequencing ◽  
Unifrac Distance ◽  
Commercial Kits ◽  
Dna Extraction Methods

Objectives:This study was performed to compare three commercial kits for the extraction of genomic DNA from anaerobic digestate for subsequent iSeq 100 sequencing and microbial community analysis.Methods:A full-scale mesophilic biogas plant was sampled, and made into aliquots of identical volumes to extract DNA using three commercial kits: FastDNA spin kit for soil (MP Biomedicals, USA), Exgene stool DNA mini (GeneAll, South Korea) and AccuPrep genomic DNA extraction kit (Bioneer, South Korea). To analyze the microbial communities in the purified DNA, 16S rDNA amplicon sequencing (V3-4 region for bacteria and V4-5 region for archaea) was performed on the Illumina iSeq 100 platform. Quality filtered sequence reads were OTU-clustered for taxonomic assignment conducted using the RDP classifier on-line.Results and Discussion:The microbial community structure visualized on the NMDS plot using the weighted UniFrac distance revealed that both bacteria and archaeal communities have phylogenetic differences depending on the DNA extraction kit used. In addition, the abundance of certain microbial populations was significantly different among the DNA extraction methods. For example, Proteobacteria was the least abundant using the soil kit, while this phylum was the most abundant when the stool kit was used. However, in the case of Thermotogae, this tendency was vice versa. The abundance of archaeal genera Methanomethylovorans and Methanosarcina was also affected by DNA extraction methods.Conclusions:The microbial populations analyzed by 16S based sequencing were affected by DNA extraction methods. To compare microbial community changes in the identical set of research, one DNA extraction method should be chosen and used consistently for the whole experiment.

Victim Participation in Japan: When Therapeutic Jurisprudence Meets Prosecutor Justice

2016 ◽  
Vol 3 (1) ◽  
pp. 135-157 ◽  
Author(s):  
Erik HERBER
Keyword(s):  
Common Sense ◽  
Relevant Literature ◽  
Therapeutic Jurisprudence ◽  
Therapeutic Effects ◽  
Criminal Trials ◽  
Policy Documents ◽  
Therapeutic Needs ◽  
Victim Participation ◽  
Court Proceedings ◽  
Therapeutic Perspective

AbstractThis article examines how a therapeutic perspective on victim participation has been conceptualized and implemented in criminal trials in Japan after procedural reforms in 2000 and 2008. Findings are discussed with reference to therapeutic jurisprudence studies on victim participation and relevant literature on Japanese criminal justice. Analysis of policy documents, survey data, interviews, and minutes of Ministry of Justice “expert meetings” reveals how the therapeutic needs of victims and the therapeutic effects of victim participation in court proceedings have been understood and conceptualized based on generalized common-sense assumptions of legal practitioners. In court, participants’ reference to victims’ wellbeing and recovery puts pressure on judges to impose harsher punishment than usual, while reinforcing the position of prosecutors. The adopted therapeutic perspective, combined with traditionally expected displays of remorse, furthermore has the effect of limiting the defence’s ability to argue facts and circumstances favourable to the defendant.

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