scholarly journals Lipid Profile in School Children Infected with Urinary Schistosomiasis in Fante Akura-Yeji, Ghana

2020 ◽  
pp. 28-34
Author(s):  
Ruth. C. Brenyah ◽  
Cephas Effah Boakye ◽  
Enos Amoako Oduro ◽  
Solomon Sosu Quarshie ◽  
Precious Kwablah Kwadzokpui ◽  
...  
Keyword(s):  
Serum Level ◽  
Lipid Profile ◽  
School Children ◽  
Density Lipoprotein ◽  
Infection Intensity ◽  
Serum Levels ◽  
Low Density ◽  
Urinary Schistosomiasis ◽  
The Mean ◽  
Study Participants

Background: Schistosomiasis remains one of the most common parasitic diseases worldwide causing considerable deaths especially among people in the Sub-Saharan region. This study determined the association between urinary Schistosomiasis and lipid profile among school children in Fante Akura, Yeji. Materials and Methods: This simple randomized case-control study was conducted among 50 primary school students with Schistosoma haematobium infection and 50 healthy control students in Fante Akura, Yeji, from January, 2014 to March, 2014. Urine and blood samples were obtained and examined for the presence of S. haematobium and assessed their lipid profile respectively. A structured questionnaire was employed to obtain information from the study participants on their socio-demographic characteristics as well as on the risk factors that can predispose study participants to S. haematobium infection. Results: The mean serum level of low-density lipoprotein cholesterol (LDL-C) was reduced significantly in schistosome-infected participants in comparison to controls (P<0.001). The mean serum levels of triglyceride (TG) (p=0.028), LDL-C (p=0.011) were significantly higher in participants with light S. haematobium infection intensity compared to participants with heavy S. haematobium infection intensity (P=0.028). The mean serum level of total cholesterol (TC) and high-density lipoprotein cholesterol (HDL-C) were higher (P>0.05) in participants with light SH infection intensity compared to participants with heavy SH infection intensity. Conclusion: S. haematobium infection presented significant changes in serum levels of total cholesterol, triglycerides and low-density lipoproteins in participants infected with S. haematobium with a corresponding raised urine parasite count.

scholarly journals Effect of Whole Quail (Coturnix japonica) Egg Consumption on some Reproductive Parameters and Lipid Profile of Male Albino Rat (Rattus norvegicus)

2017 ◽  
Vol 9 (3) ◽  
pp. 315-320 ◽  
Author(s):  
Chidozie N. OKOYE ◽  
Samuel O. EKERE ◽  
Onyinyechukwu A. AGINA ◽  
Ikechukwu J. UDEANI ◽  
Chukwunonso K. EZEASOR
Keyword(s):  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Control Group ◽  
Low Density ◽  
Epididymal Sperm ◽  
Treatment Groups ◽  
Egg Consumption ◽  
Group A ◽  
The Mean

The present study evaluated the effect of whole egg consumption on the liver, testes, cauda epididymal sperm reserve and lipid profile of male rats. These evaluations were carried out on adult twenty (20) male albino rats, which were randomly selected into four groups of 5 rats each, designated groups A, B, C and D. Group A was the control group and received only equivalent volume of distilled water, while groups B, C and D received 0.25mg/kg, 0.5mg/kg; and 1.0mg/kg body weight of the quail egg respectively. Standard procedures were carried out in the tissue processing, cauda epididymal sperm reserve and in lipid profile determinations. On days 35 and 49, the mean serum total cholesterol value of group D was significantly lower than that of the control group. On day 35, the mean serum low density lipoprotein and high density lipoprotein (LDL and HDL cholesterol) values of all the treatment groups were significantly lower and higher than that of the control group, respectively. However, on days 49 and 63, the mean serum very low density lipoprotein (VLDL cholesterol) and triglyceride values of all the treatment groups were significantly higher than that of the control group. A significant increase in cadual epididymal sperm count (CESR) was recorded on day 63 at the mid and high doses. No obvious pathological lesions were observed in the histomorphology of the testes and liver when compared to the control. Therefore, whole quail egg consumption caused an increase in serum triglyceride and very low density lipoprotein concentration, and also improved fertility. In other words, prolonged consumption of quail egg should be done with caution as it may predispose one to cardiovascular disease.

scholarly journals Hubungan Kadar LDL dan HDL Serum Ibu Hamil Aterm dengan Berat Lahir Bayi

2014 ◽  
Vol 3 (3) ◽  
Author(s):  
Oktalia Sabrida ◽  
Hariadi Hariadi ◽  
Eny Yantri
Keyword(s):  
Birth Weight ◽  
Serum Level ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Serum Levels ◽  
Term Pregnancy ◽  
Cross Sectional ◽  
Consecutive Sampling ◽  
The Mean ◽  
Infant Birth

AbstrakAda anyak penelitian yang membuktikan transfer kolesterol dari ibu ke janin melalui lapisan trofoblas yang membawa partikel LDL (Low Density Lipoprotein) dan HDL (High Density Lipoprotein). Pengambilan dan pemanfaatan LDL oleh plasenta merupakan mekanisme alternatif oleh janin untuk memperoleh asam lemak dan asam amino esensial. Tujuan penelitian ini untuk mengetahui hubungan kadar LDL dan HDL serum ibu hamil aterm dengan berat lahir bayi. Penelitian ini merupakan studi observasional dengan rancangan cross sectional. Dilakukan pemeriksaan kadar LDL dan HDL serum terhadap 31 sampel ibu hamil aterm yang dipilih secara consecutive sampling, kemudiaan saat bayi dari sampel lahir dilakukan penimbangan berat lahir bayi dalam 1 jam setelah lahir dengan keadaan tanpa pakaian. Data dianalisis menggunakan uji korelasi Pearson dilanjutkan dengan uji regresi linier sederhana, nilai p<0.05 dianggap bermakna secara statistik. Rerata kadar LDL serum ibu hamil aterm 138,52±37,86 mg/dl dengan 7 sampel (22,60%) kadar LDL <101 mg/dl. Rerata kadar HDL serum ibu hamil aterm 53,32±17,39 mg/dl dengan 13 sampel (41,90%) kadar HDL <48 mg/dl. Rerata berat lahir bayi 3150,00±489,89 gram dengan 2 sampel (6,50%) memiliki bayi dengan berat<2500 gram. Terdapat hubungan positif antara kadar LDL serum ibu hamil aterm dengan berat lahir bayi, kekuatan hubungan lemah (r=0,258), secara statistik tidak bermakna (p=0,161). Terdapat hubungan positif antara kadar HDL serum ibu hamil aterm, kekuatan hubungan sangat lemah (r=0,035), secara statistik tidak bermakna (p=0,850). Kesimpulan penelitian tidak terdapat hubungan kadar LDL dan HDL serum ibu hamil dengan berat lahir bayi.Kata kunci: kadar LDL serum, kadar HDL serum, ibu hamil aterm, berat lahir bayiAbstractMany studies proved that the transferring of cholesterol from mother to fetus through the trophoblastic layer carried LDL (Low Density Lipoprotein) and HDL (High Density Lipoprotein) particles. Uptake and usage of LDL by placenta to the fetus is an alternative mechanism to obtain fatty acids and essential amino acids. The objective of this study was to determine whether there is a relationship between LDL and HDL serum level of pregnant women at term with infant birth weight. This study was an observational study with cross sectional design. Examination of LDL and HDL serum level to 31 term pregnancy sample choose by consecutive sampling, and then infant’s birth weight was counted within 1 hour after birth without clothes. The data analyzed with Pearson correlation statistical test followed by simple linier regression statistical test. The mean of LDL serum level term pregnancy was 138,52±37,86mg/dlwith7 samples(22.60%) in LDL levels<101 mg/dl. The mean of HDL serum level at term pregnancy was 53,32±17,39 mg/dlwith 13 samples (41,90%) in HDL levels<48 mg/dl. The mean of infant birth weight was 3150,00±489,89 grams with 2 samples (6,50%) had infants weighing < 2500 grams. There is a positive relationship between LDL serum levels term pregnancy with birth weight infants, the strength of the relationship is weak (r =0,258), were not significant statistically (p=0,161). There is a positive relationship between HDL serum levels at term pregnancy with birth weight infants, the strength ofthe relationshipis veryweak(r =0,035), were not significant statistically (p=0,850). In conclusion there was no correlation of serum levels of LDL and HDL at term pregnant with birth weight.

scholarly journals Serum Level of Interleukin-33, C-Reactive Protein, and Troponin in Iraqi Coronary Artery Disease Patients

2020 ◽  
pp. 314-321
Author(s):  
Athraa Z. Al-Obaidi ◽  
Jinan M. J. Al-Saffar
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Serum Level ◽  
Lipid Profile ◽  
Supply And Demand ◽  
Density Lipoprotein ◽  
Serum Levels ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Artery Disease

     Coronary artery disease (CAD) is a condition of an inadequate supply of oxygenated blood to a portion of the myocardium. It typically occurs when there is an imbalance between supply and demand of myocardial oxygen. The most common cause of myocardial ischemia is atherosclerotic disease of an epicardial coronary artery or arteries which is sufficient to cause a regional reduction in myocardial blood flow and inadequate perfusion of the myocardium supplied by the involved coronary artery. Fifty CAD subjects (23 females and 27 males) were enrolled in this study in addition to thirty healthy control subjects (13 female and 17 male). This study aimed to measure the serum levels of interleukin IL- 33, C- reactive protein and troponin in CAD and their association with lipid profile by using enzyme-linked immune sorbent assay (ELISA). T results showed that high-density lipoprotein (HDL) was statistically high while differences in cholesterol, triglyceride and low-density lipoprotein (LDL) were statistically non-significant between CAD patients and controls. Moreover, the serum level of IL-33 and CRP were statistically higher in patients than controls, while troponin levels were not significantly different. In addition, the present study demonstrates that IL-33, CRP, and Troponin were not associated with lipid profile. The relationship of IL-33 with CRP and troponin was non-significant.

Effect of Selenium Supplementation on Lipid Profile: A Systematic Review and Meta-Analysis

2018 ◽  
Vol 50 (10) ◽  
pp. 715-727 ◽  
Author(s):  
Motahareh Hasani ◽  
Shirin Djalalinia ◽  
Farshad Sharifi ◽  
Mehdi Varmaghani ◽  
Maryam Zarei ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Fixed Effects ◽  
Meta Analysis ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Selenium Deficiency ◽  
Serum Levels ◽  
Selenium Supplementation ◽  
Low Density ◽  
Fixed Effects Model

AbstractSelenium is an essential mineral that plays a key role in plenty of major metabolic processes. A growing body of literature has shown that selenium deficiency leads to an increase in plasma TC and TG levels. This study explores the effect of selenium supplementation on serum level of lipid profile [total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL), high-density lipoprotein (HDL), very low density lipoprotein (VLDL)]. We systematically searched PubMed/MEDLINE, ISI/WOS, and Scopus (from their commencements to Jan 2016) to identify the papers investigating the association between the intake of selenium and lipid profile. Data extracted from the relevant studies were screened. The pooled standardized mean difference was estimated using the random or fixed effects model. Heterogeneity among the studies was assessed using Q-test. Of the potentially relevant articles screened, 11 articles including 1221 participants were included in this meta-analysis. Results of meta-analysis showed that intake of selenium resulted in a statistically significant improvement in TC, [(SMD): –0.13, 95% CI: (–0.24, –0.02)], TG [(SMD): –0.19, 95% CI: (–0.38, –0.01)] and VLDL [(SMD): –0.34, 95% CI: (–0.63, –0.05)]. The selenium supplementation did not significantly improve lipid profile such as LDL [(SMD): –0.08, 95% CI: (–0.036, 0.19)], HDL [(SMD): 0.01, 95% CI: (–0.164, 0.18)], HDL/TC ratio [(SMD): 0.025, 95% CI: (–0.11, 0.16)], non-HDL-C [(SMD): 0.018, 95% CI: (–0.13, 0.16)]. This meta-analysis suggests that the effect of selenium supplementation on the serum levels of TG and VLDL is marginally significant. However, the supplementation has no effect on other serum lipids. Moreover, the study shows that the effect of selenium supplementation on lipid profile is negative.

scholarly journals Study on Lipid Profile in Offspring of Dyslipidemic Parents

2012 ◽  
Vol 17 (1) ◽  
pp. 37-40
Author(s):  
MKH Azad ◽  
SS Hussain ◽  
MBK Choudhury ◽  
FR Mowsumi
Keyword(s):  
Cardiovascular Disease ◽  
High Density Lipoprotein ◽  
Lipid Profile ◽  
Genetic Predisposition ◽  
Matched Control ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Low Density ◽  
The Mean ◽  
Age And Sex

As dyslipidemia is responsible for remarkable cause of cardiovascular disease which is considered as the number one cause of death globally, this study was undertaken to evaluate the lipid profile status of offspring of dyslipidemic parents in comparison with the offspring of normolipidemic parents. In this study, carried out on 89 subjects, the mean total cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL-c) and low density lipoprotein (LDL-c) were 162.18 ± 20.97, 168.98 ± 33.51, 39.09 ± 3.62 and 90.41 ± 18.64 mg/dl respectively in adolescents with parental dyslipidemia and 158.38 ± 12.67, 157.22 ± 15.06, 40.51 ± 2.90 and 86.42 ± 12.39 mg/dl respectively in control adolescents. There were significant differences (p < 0.05) of TG and HDL-c between cases and controls where HDL-c choesterol was significantly lower in offspring of dyslipidemic parents then the offspring of normolipidemic parents. The findings of this study reflect the association of offspring dyslipidemia with parental dyslipidemia, probably due to some genetic predisposition. Offspring of dyslipidemic parents have higher levels of TC, TG, LDL-c and lower level of HDL-c compared to age and sex matched control subjects. DOI: http://dx.doi.org/10.3329/jdnmch.v17i1.12191 J. Dhaka National Med. Coll. Hos. 2011; 17 (01): 37-40

scholarly journals Potential Cardiovascular Risk Protection of Bilirubin in End-Stage Renal Disease Patients under Hemodialysis

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Maria do Sameiro-Faria ◽  
Michaela Kohlova ◽  
Sandra Ribeiro ◽  
Petronila Rocha-Pereira ◽  
Laetitia Teixeira ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Serum Levels ◽  
Paraoxonase 1 ◽  
Low Density ◽  
Genotype Distribution ◽  
Apo B ◽  
Risk Protection

We evaluated the potential cardiovascular risk protection of bilirubin in hemodialysis (HD) patients. An enlarged set of studies were evaluated in 191 HD patients, including hematological study, lipid profile, iron metabolism, nutritional, inflammatory markers, and dialysis adequacy. The TA duplication screening in the UDP-glucuronosyltransferase 1 A1 (UGT1A1) promoter region was also performed. TheUGT1A1genotype frequencies in HD patients were 49.2%, 42.4%, and 8.4% for 6/6, 6/7, and 7/7 genotypes, respectively. Although no difference was found inUGT1A1genotype distribution between the three tertiles of bilirubin, significant differences were found with increasing bilirubin levels, namely, a decrease in platelet, leukocyte, and lymphocyte counts, transferrin, oxidized low-density lipoprotein (ox-LDL), ox-LDL/low-density lipoprotein cholesterol ratio, apolipoprotein (Apo) A, Apo B, and interleukin-6 serum levels and a significant increased concentration of hemoglobin, hematocrit, erythrocyte count, iron, transferrin saturation, Apo A/Apo B ratio, adiponectin, and paraoxonase 1 serum levels. After adjustment for age these results remained significant. Our data suggest that higher bilirubin levels are associated with beneficial effects in HD patients, by improving lipid profile and reducing the inflammatory grade, which might contribute to increase in iron availability. These results suggest a potential cardiovascular risk protection of bilirubin in HD patients.

Lipid Profile, Low-Density Lipoprotein Oxidation and Ceruloplasmin in the Progeny of Families with a Positive History of Cardiovascular Diseases and/or Hyperlipidemia

Angiology ◽  
2009 ◽  
Vol 60 (4) ◽  
pp. 455-461 ◽  
Author(s):  
Kali G. Makedou ◽  
Dimitri P. Mikhailidis ◽  
Areti Makedou ◽  
Stavros Iliadis ◽  
Anargyros Kourtis ◽  
...  
Keyword(s):  
Family History ◽  
Cardiovascular Diseases ◽  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Positive Family History ◽  
Density Lipoprotein ◽  
Serum Levels ◽  
Low Density ◽  
Lipid Peroxidation Product ◽  
Positive History

Fifty-eight healthy progeny (mean age ± SD 13.9 ± 7.9 years) of 39 families with a positive history for Cardiovascular Diseases ([CVD] n = 44) or hyperlipidemia (n = 14) were included in the study and were compared with 30 age-matched control participants, with a negative family history, to evaluate lipid profile, ceruloplasmin (Cp), and lipid peroxidation product (malondialdehyde [MDA]) levels, as well as in vitro copper-induced Low-density lipoprotein (LDL) oxidizability. Mean serum levels of total cholesterol, LDL cholesterol (LDL-C), apolipoprotein B-100, and MDA of the participants were significantly higher than those of the controls. Lag time, an LDL resistance oxidation marker, was lower in the study group and negatively correlated with LDL-C ( r = -.437, P < .05) and Cp ( r = -.272, P < .05) serum levels. In conclusion, progeny with a positive family history for CVD or hyperlipidemia have an atherogenic lipid profile and increased LDL susceptibility to oxidation. High Cp levels seem to be related to lower resistance of LDL to oxidation.

scholarly journals Lipid Profile in Preeclampsia Patients as Compared to Normal Patient

2020 ◽  
Vol 22 (4) ◽  
pp. 238-242
Author(s):  
Sanita Kayastha ◽  
B Tiwari ◽  
R Subedi
Keyword(s):  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
College Teaching ◽  
Test Group ◽  
Control Group ◽  
Low Density ◽  
Medical College ◽  
The Mean ◽  
Severity Of The Disease

The main objective of the study was to see the association of dyslipidemia in preeclampsia (PET) as compare to normotensive (NT) patients. It was a descriptive study done in Nepal Medical College Teaching Hospital Department of Obstetrics and Gynecology from April 2019 from April 2020. A total of 75 PET (test group) and 75 NT (control group) in their third trimester were included. Their fasting lipid profile was studied. It was found that triglyceride (TG) and very low density lipoprotein (VLDL) was significantly high among PET group as compared to that of NT patients. The mean TG of PET group was 266.11± 98.61 and the NT group was 187±58.56 (p=0.00) and the mean VLDL of PET group was 46.00±15.31 and NT group was 37.88±12.85 (p=0.001). On the other hand, the total cholesterol (TC), low density lipoprotein (LDL) and high density lipoprotein (HDL) were not significantly different in both the groups. It was also found that with the severity of the disease (Preeclampsia), the level of TG and VLDL increased significantly. Therefore, among the investigation done for PET, we should include lipid profile, especially the TG and VLDL. Furthermore, TG and VLDL should be measured serially (at least once a week) so as to predict the progress of PET and manage the patient accordingly.

scholarly journals Study of Correlation between Iron Deficiency Anemia and Serum Lipid Profile in a Tertiary Care Center

2021 ◽  
Vol 4 (1) ◽  
pp. 446-449
Author(s):  
Mahima Bataju ◽  
Binita Bhattarai ◽  
Apeksha Niraula ◽  
Anamika Priyadarshinee ◽  
Santosh Gautam
Keyword(s):  
Iron Deficiency ◽  
High Density Lipoprotein ◽  
Lipid Profile ◽  
Iron Deficiency Anemia ◽  
Serum Lipid ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Deficiency Anemia ◽  
Low Density ◽  
The Mean

Introduction: Looking at the health status of our country Nepal, iron deficiency anemia fits rightly in our socioeconomic status and dyslipidemia is the rising one along with being more highlighted these days. Some studies show an association between iron deficiency anemia and dyslipidemia but the data are controversial. Therefore, this study is aimed to find the relationship between iron deficiency anemia and serum lipid profile in the Nepalese context.Materials and Methods: A cross-sectional study was conducted in KIST Medical College and Teaching Hospital from June 2019 to August 2020. 76 Iron deficiency anemia and 75 age and sex-matched healthy control were investigated for any possible changes in serum lipid profile: triglyceride, low-density lipoprotein, high-density lipoprotein, and total cholesterol.Results: The mean triglyceride in case and control was 92.96 mg/dl and 99.87 mg/dl respectively. The difference between these two groups was statistically significant (p=<0.001). Moreover, serum total cholesterol level in the case (138.82 mg/dl) was significantly lower than the control (146.67 mg/dl). The mean high-density lipoprotein was almost the same in anemic and non-anemic groups, p=<0.001. While the mean low-density lipoprotein in theiron-deficiency anemia group was significantly lower than the control group (p=<0.001).Conclusions: In this study, the values of the lipid profile parameters: triglyceride, low-density lipoprotein, high-density lipoprotein, and total cholesterol in cases were found to be lower than those in the controls.

Effect of Turmeric and Ginger on Lipid Profile in Male Rats Exposed to Oxidative Stress

2019 ◽  
Vol 10 (01) ◽  
Author(s):  
Eman A. Al-Rekabi ◽  
Dheyaa K. Alomer ◽  
Rana Talib Al-Muswie ◽  
Khalid G. Al-Fartosi
Keyword(s):  
Oxidative Stress ◽  
Hydrogen Peroxide ◽  
Drinking Water ◽  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Male Rats ◽  
Control Group ◽  
Very Low Density Lipoprotein ◽  
Low Density

The present study aimed to investigate the effect of turmeric and ginger on lipid profile of male rats exposed to oxidative stress induced by hydrogen peroxide H2O2 at a concentration of 1% given with consumed drinking water to male rats. Methods: 200 mg/kg from turmeric and ginger were used, and the animals were treatment for 30 days. Results: the results showed a significant increase in cholesterol, triglycerides, low density lipoprotein (LDL), very low density lipoprotein (VLDL), whereas it explained a significant decrease in high density lipoprotein (HDL) of male rats exposed to oxidative stress when compared with control group. the results showed a significant decrease in cholesterol, triglycerides, (LDL), (VLDL), whereas it explained a significant increase in (HDL) of rats treated with turmeric and ginger at dose 200 mg/kg when compared with male rats exposed to oxidative stress.

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