Clinical examination of 102 patients including, besides objective neurological examination, determination of functional state of vegetative nervous system, electroencephalography, reoencephalography, stomatologic examination, stomatoscopy, measurement of microcurrent in oral cavity, was carried out. Biochemical investigation involved determination of the total content of testosteron, biologically active free forms of it, concentration of B-endorphine, series E prostaglandines. In 81,3% of patients in vegetative security sympatho-tonic, in 7,8% vagotonic and in 10,7% mixed responses were dominant. Change in electroencephalograms and reoencephalograms of the examined patients differed in their dependence on vegetative state. Findings of stomatological examination and stomatoscopy allowed to estimate objectively local changes in oral cavity. The obtained results evidently show the dependence of suprasegmental structures of brain, and of the pituitary bodyadrenal gland system as well.