scholarly journals Allergic Reaction of the Body to Drugs Used in Dental Practice

Author(s):  
Anastasiia Vladimirovna Shefova ◽  
Andrey Olegovich Galustyan ◽  
Angelina Olegovna Shershneva ◽  
Olga Vladimirovna Tyukavina ◽  
Marina Mikhailovna Krekova ◽  
...  

The article examines allergic reactions of the body to drugs used in dental practice. The authors note that adverse or allergic reactions of medicines to the human body are possible with any medications that are prescribed or administered in a dental office. Although most of the pharmacological agents used today have a favorable profile and they are relatively safe, a modern specialist should be aware of potential adverse reactions that may occur and one should be ready to cope with any complications. Adverse or allergic reactions are possible when working with drugs such as local anesthetics, sedatives, analgesics and antibiotics, for this reason, it is necessary to study the possible reactions of the patient's body to them when administering such drugs to reduce the negative impact on the body. In general, the pharmacological arsenal of a practicing dentist is relatively safe today. However, a prudent clinician should be aware of potential adverse reactions that may occur as a result of taking medications, and be confident in the treatment of such complications.

Medicina ◽  
2021 ◽  
Vol 57 (8) ◽  
pp. 782
Author(s):  
Entaz Bahar ◽  
Hyonok Yoon

The most widely used medications in dentistry are local anesthetics (LA), especially lidocaine, and the number of recorded adverse allergic responses, particularly of hazardous responses, is quite low. However, allergic reactions can range from moderate to life-threatening, requiring rapid diagnosis and treatment. This article serves as a review to provide information on LA, their adverse reactions, causes, and management.


2021 ◽  
Vol 16 (4) ◽  
pp. 77-83
Author(s):  
Anna Yatsenko ◽  
Lidiya Trankovskaya ◽  
Olga Artyulova

Subject. The scientific works of recent years show an increase in the degree of negative impact of vitamin deficiency and vitamin-like substances on the state of health of the population. With the deficiency of most vitamins, synthetic processes and regeneration of oral tissues are reduced, so often the initial signs of hypovitaminosis are stomatitis, gingivitis, glossitis, and therefore, it is dentists who are the first to diagnose deviations in the body associated with vitamin deficiency. This justifies the relevance and practical value of studying and describing clinical cases of manifestations of deficient vitamin conditions in the oral cavity. The object – is to study the effect of B vitamins on the oral mucosa in order to increase the effectiveness of diagnosis of vitamin-deficient conditions of the human body. Methodology. These clinical examples illustrate the management experience of patients with manifestations of deficient vitamin conditions on the oral mucosa. Clinical and laboratory methods of diagnosing the analysed conditions of the organism were applied. Statistical processing of materials was carried out using the STATISTICA 10 software (StatSoft, Inc., USA). Results. The deficient condition of the organism in relation to vitamins B2, B6, B12 in patients 18-75 years old has been studied. Characteristic clinical changes on the oral mucosa of the examined patients were established. So, in most patients with vitamin B2 deficiency, the classic Sebrel triad was found: dermatitis, glossitis, cheilitis. In those examined with a lack of vitamin B6, language desquamations (smoothed, polished language) were determined in the 83.6%, often combined with glossodinia. Patients with vitamin B12 deficiency were characterized by a lesion in the form of Meller-Gunter glossitis in 74.9% of cases, moreover, 67.6% of patients showed paresthesia in the area of tongue and oral mucosa. Conclusions. The study found that the first clinical symptoms of deficient conditions of the presented vitamins of group B were found from the oral cavity. Thus, it is the dentist who is the first to diagnose the pathological states of lack of group B vitamins in the human body, which emphasizes the importance and relevance of continuing to study these states of the body.


2009 ◽  
Vol 6 (6) ◽  
pp. 26-33
Author(s):  
Lyudmila Vasil'evna Luss ◽  
T Yu Repina ◽  
E B Tuzlukova ◽  
L V Luss ◽  
T Ju Repina ◽  
...  

There is an increasing of allergic reactions on the so called «hidden» allergens during the last years. Nowadays a lot of allergens and various compositions could be regarded as the so called «hidden» allergens. At the same time their role in adverse reactions as well as in allergic reactions is not clear. This review is devoted to definition, classification and clinical contribution of «hidden» allergens. The allergic reaction to «hidden» allergen in genferon preparation is described as a clinical example.


2012 ◽  
Vol 63 (1) ◽  
pp. 35-40 ◽  
Author(s):  
Martina Nadih ◽  
Zvonimira Knežević ◽  
Renata Josipović ◽  
Ivanka Grgić ◽  
Ante Cvitković

Pollen Counts in Slavonski Brod, Croatia During the Pollination Period 2008 to 2010Hay fever or pollinosis is the allergic reaction of the human body to allergic pollen grains and is a seasonal phenomenon. Pollen concentrations depend on the climate, geographic features, and vegetation. Trees, grass, and weed pollinosis is frequent in Croatia, common ragweed (Ambrosia artemisifolia L.) pollinosis in particular. Continuous monitoring of pollen air concentrations can provide timely information to the general public and can help sensitised patients and their physicians to prevent or alleviate allergic reactions. This is the task of health ecology services such as our Public Health Institute of the Brod-Posavina County. This article reports pollen concentrations in Slavonski Brod measured in March 2008 to November 2008, March 2009 to October 2009, and April 2010 to October 2010 and discusses the increasing exposure to ragweed and ways to control it.


2020 ◽  
Vol 5 (1) ◽  
pp. 35-42
Author(s):  
Solomiya Pysarevska ◽  
◽  
Victoriya Vaschuk ◽  
Zinoviy Yaremko ◽  
◽  
...  

The article analyzes how young people adhere to the axiomatic rule of life safety, which should be treated as the most dangerous factor in the use of mobile devices of modern information technologies with a factor whose influence on the human body is not established. As the first step to avoiding the undesirable effects of any potential dangers is to realize their presence in the human environment, so the purpose of this study is to find out what is the attitude of young people, including students, to the use of mobile phones and whether they comply with basic security measures. to minimize potential negative impact. The object of the study is the prerequisites for the formation of smartphone dependency in young people and awareness of the potential dangers of mobile use. The results of the study of the age at which students started using a mobile phone and the frequency of its use for various purposes revealed possible signs of development in students of smartphone dependence. This is evidenced by the high percentage of those who received a cellphone for use early (50–60% between 9–12 years old) and the almost constant use of half of the students surveyed. Because the earlier a mobile phone is used, the more adverse its effect on the human body, since children are more susceptible to electromagnetic radiation than adults. According to the survey, 30–40% of students began to actively use a mobile phone at a fairly early age – 6–8 years. It has been found that students are not aware of the potential dangers of using mobile phones. This is confirmed by the students' low level of knowledge and interest in the indicators that characterize phone security; a small proportion of those who consider the safety of the phone when choosing a mark and model along with other features; as well as a significant percentage of students who do not adhere to safety measures, including increasing the distance from the body while storing a mobile phone


ISRN Allergy ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-5
Author(s):  
Shilpa Shah

IgE recognition of autoantigens might augment allergic inflammation in the absence of exogenous allergen exposure. Among allergy and autoimmunity, there is disproportionate representation of males before puberty and females after puberty, suggesting a role for sex hormones. Hormone allergy is an allergic reaction where the offending allergens are one's own hormones. It is an immune reaction to the hormones, which can interfere with the normal function of the hormones. It can occur perimenstrually in women along with the variation in menstrual cycle. The perimenstrual allergies are about the cyclic abundance of the hormone causing a cyclic expression of allergic symptoms. The inflammatory mechanisms of allergic reactions to hormone allergens, which are intrinsic to the body, are the same as the mechanisms of allergic reactions to external allergens.


2018 ◽  
Vol 1 (12) ◽  
pp. 365-370 ◽  
Author(s):  
Tarun Kalra ◽  
Geeta Kalra ◽  
Mohit Bansal ◽  
Swati Uppal

The success in any practice is dependent on efficient workflow, with minimum risk to injury and cumulative trauma. Work in a dental office calls for deftness in cognitive abilities and can, more often than not, be physically challenging. Repeated use of movements and postures that go against the natural or anatomical alignment and limitations of the human body often lead to what is known as cumulative trauma leading to development of musculoskeletal disorders. The whole idea of ergonomics in the workplace is to avoid any such exigencies. Through this review it is intended to bring forth the widely known yet often neglected aspect of dental practice; that is the human factor in workplace efficiency.


Author(s):  
I.S. Lisetska ◽  

The literature review focuses on the prevalence of smoking among the population, the types of smoking devices and their negative impact on public health. The article presents the composition of traditional cigarettes and alternative types of smoking, analyzes the data of smoking statistics in the world. The smoking habit has been known since 2000 BC, when American Indians inhaled the smoke from burning the leaves of the plant Nicotiana tabacum, in the 20th century became an epidemic and killed more than 100 million people, and according to forecasts in the XXI century, this figure may grow in order. It is alarming that in recent decades, in addition to traditional cigarettes, alternative types of smoking have become popular, especially among adolescents and young people, namely electronic cigarettes (E-cigarettes, vapes), tobacco heating devices (IQOS), and sometimes products. With low tobacco content (snuff, chewing tobacco, etc.). In addition, hookah remains fashionable and sometimes prestigious among young people, which also has a detrimental effect on the human body. Smoking both traditional cigarettes and alternative types is one of the important medical and social problems both in Ukraine and around the world, as it is widespread and available. Smoking is a risk factor for human health and, as a result, an increase in nicotine-related mortality. At the same time, smoking is the only cause of illness and death that can be eliminated. Today, smoking is considered not as a bad habit, but as a chronic disease, prone to recurrence, even long after smoking cessation. There are no safe types of smoking, active and passive smoking are equally harmful to the body, which undermines human health and threatens his life. Smoking is especially dangerous for adolescents and young adults. The fight against smoking remains a key factor in the recovery of the nation. Smoking cessation is not only a matter of prevention, it should be considered as one of the appointments for the patient in the treatment of any disease and rehabilitation, because without it there will be no success in treatment and health. No conflict of interest was declared by the author. Key words: smoking, cigarettes, nicotine, electronic cigarettes, IQOS, hookah, snus.


2019 ◽  
Vol 31 (4) ◽  
pp. 975-980
Author(s):  
Hristijan Spasov ◽  
Mire Spasov ◽  
Icko Gjorgoski ◽  
Majlinda Ademi

Allergic reactions in the body are initiated by non-pathogenic allergens that cause hypersensitivity to the immune system of the type I hypersensitivity group, characterized by excessive activation of the cells of the white blood cell, mast cells and basophils by IgE, resulting in an inflammatory response. The particles of the allergen in the body mainly penetrate the mucous membranes of the body openings causing a series of reactions by activating T cells and B cells. The main symptoms of allergic reactions are secretion from the mucous membrane, irritation, swelling with itching and redness. The aim of the research came from the assume that in the white laboratory rat, when treated with an allergen isolated from the pollen of the Phleum pratense plant, there may be an allergic reaction, and hence a change in some parameters of the immune system.As a result of these assumptions the following specific goals were set. To determine the change in the concentration of immunoglobulins in serum from the blood taken from the rats every week for a month, to determine the variation in the total number of leukocytes, determine the number of basophils that compared to the reference value will indicate whether there are certain changes. The basophils were the target of the study because it is known that their number is the same with the number of mast cells that also increase during the allergic reaction. Our goal was also to determine the changes in the above parameters in relation to the different concentration of the allergen.As an experimental model we used white laboratory rats from the Wistar kind.All of them were female at the age of 6 to 9 weeks. The chosen age is due to their genetic predisposition to develop Th2-type cells that are involved in the immune response to the model of the allergy that has been studied. The rats were divided into three groups of six animals, the first group of rats being treated with an allergen in a quantity of 5 μL, adsorbed in 100 μl Al (OH) 3 (Serva, Heidelburg, Germany, 2 mg / mL) in a total volume of 150 μl sterile PbS., treated with a recombinant allergen from Phleum pratense at room temperature, a second group treated with an allergen in an amount of 2.5 μl, and a third group of control rats that are not treated and serve to compare the results. Our studies have shown that in the treatment with an allergen isolated from the pollen of the plant Phleum pratense at concentrations of 5 μl and 2.5 μl,the white laboratory rat develops an allergic reaction with a change in the concentration of immunoglobulins, changes in the total number of leucocytes, the percentage of lymphocytes , monocytes and basophils. The results obtained by the ELISA test of the two volumes show that the concentrations of immunoglobulins during the experimental period of day by day, are continuously increasing, and are proportional to the volume of the allergen.


2018 ◽  
Vol 68 (12) ◽  
pp. 2860-2864
Author(s):  
Georgiana Macovei ◽  
Antonela Maria Beldiman ◽  
Mihaela Monica Scutariu ◽  
Adina Oana Armencia ◽  
Zenovia Surlari ◽  
...  

Pain is one of the most common reasons for patients scheduling or avoiding appointments in the dental office. This symptomatology which is commonly associated with fixed orthodontic treatment, may have a negative impact on the quality of life of the patient and may cause absences from periodic appointments. Interdisciplinary orthodontic treatment has a clear positive effect on psychological, functional, social health but also involves pain and discomfort, at least in the early stages or until the adaptability of the body occurs. The use of NiTi archwires during the first stages of treatment provides the development of physiological forces, but depending on each patient pain threshold, dental pain is perceived.


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