scholarly journals DIAGNOSIS OF ORAL MUCOSAL PATHOLOGY IN PATIENTS WITH VARIOUS MANIFESTATIONS OF GROUP B VITAMIN IMBALANCE

2021 ◽  
Vol 16 (4) ◽  
pp. 77-83
Author(s):  
Anna Yatsenko ◽  
Lidiya Trankovskaya ◽  
Olga Artyulova
Keyword(s):  
Oral Cavity ◽  
Oral Mucosa ◽  
Human Body ◽  
Clinical Symptoms ◽  
Negative Impact ◽  
Vitamin B12 Deficiency ◽  
Vitamin Deficiency ◽  
The Body ◽  
B Vitamins ◽  
Group B

Subject. The scientific works of recent years show an increase in the degree of negative impact of vitamin deficiency and vitamin-like substances on the state of health of the population. With the deficiency of most vitamins, synthetic processes and regeneration of oral tissues are reduced, so often the initial signs of hypovitaminosis are stomatitis, gingivitis, glossitis, and therefore, it is dentists who are the first to diagnose deviations in the body associated with vitamin deficiency. This justifies the relevance and practical value of studying and describing clinical cases of manifestations of deficient vitamin conditions in the oral cavity. The object – is to study the effect of B vitamins on the oral mucosa in order to increase the effectiveness of diagnosis of vitamin-deficient conditions of the human body. Methodology. These clinical examples illustrate the management experience of patients with manifestations of deficient vitamin conditions on the oral mucosa. Clinical and laboratory methods of diagnosing the analysed conditions of the organism were applied. Statistical processing of materials was carried out using the STATISTICA 10 software (StatSoft, Inc., USA). Results. The deficient condition of the organism in relation to vitamins B2, B6, B12 in patients 18-75 years old has been studied. Characteristic clinical changes on the oral mucosa of the examined patients were established. So, in most patients with vitamin B2 deficiency, the classic Sebrel triad was found: dermatitis, glossitis, cheilitis. In those examined with a lack of vitamin B6, language desquamations (smoothed, polished language) were determined in the 83.6%, often combined with glossodinia. Patients with vitamin B12 deficiency were characterized by a lesion in the form of Meller-Gunter glossitis in 74.9% of cases, moreover, 67.6% of patients showed paresthesia in the area of tongue and oral mucosa. Conclusions. The study found that the first clinical symptoms of deficient conditions of the presented vitamins of group B were found from the oral cavity. Thus, it is the dentist who is the first to diagnose the pathological states of lack of group B vitamins in the human body, which emphasizes the importance and relevance of continuing to study these states of the body.

scholarly journals Assessment of Micronutrient Status of Conscripts in Arctic Zone of Russian Federation

2020 ◽  
pp. 42-47
Author(s):  
N.N. Kirichenko ◽  
◽  
A.A. Novitsky ◽  
Keyword(s):  
Folic Acid ◽  
Russian Federation ◽  
Clinical Symptoms ◽  
Vitamin Deficiency ◽  
The Body ◽  
The Arctic ◽  
Winter Period ◽  
Laboratory Diagnostics ◽  
Arctic Zone ◽  
Micronutrient Status

The aim of the study is to assess the micronutrient status in the autumn and winter periods of conscripted military personnel serving in the Arctic zone of the Russian Federation (Arctic); to perform a comparative analysis of the laboratory and clinical methods used to determine micronutrient insufficiency. Materials and methods of research. The study involved 154 conscripts (all male) aged 18-25 years, healthy, service experience in the Arctic – from 4 months. In the autumn (2 points) and spring (one point) phases the following issues were studied: a set of physical health indicators; laboratory indicators of 8 vitamins (A, E, D, C, B1, B2, B12, folic acid) and 8 minerals (Fe, Ca, P, Co, Mn, Cu, Se, Cr) in the blood; symptoms of vitamin deficiency. The state of health, physical fitness, morbidity and hospitalization of the subjects were evaluated. Research results and their analysis. Data were obtained on the prevalence of hidden (subclinical) forms of vitamin deficiency, including more than 50% – for folic acid, vitamins A, E, D, C, as well as all the studied minerals - in the autumn-winter period, which is more dangerous in terms of the incidence of respiratory infections in organized contingents. The classical view of the prevalence of hypovitaminosis in the spring was revised, which was only partially confirmed for vitamins C and B1. It was found that the classical methods of diagnosis based on clinical symptoms used to determine manifest forms of hypo-and avitaminosis are ineffective for early detection of subclinical forms (prehypovitaminosis). The necessity is substantiated of wider implementation of modern means of laboratory diagnostics of micronutrient deficiency in the body using a proven method of freezing transported samples in combination with already used hygienic methods.

scholarly journals THE INTEGRATED ASSESSMENT OF EFFECTIVITY OF MINERAL WATER "FATEEVSKAYA" IN PATIENTS WHO USE REMOVABLE DENTAL CONSTRUCTIONS

2018 ◽  
Vol 14 (2) ◽  
pp. 109-114
Author(s):  
Ольга Садыкова ◽  
Ol'ga Sadykova ◽  
Сергей Жолудев ◽  
Sergey Zholudev ◽  
Антон Еликов ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Salivary Glands ◽  
Mineral Water ◽  
Ph Value ◽  
Negative Impact ◽  
Secretory Activity ◽  
Salivary Secretion ◽  
The Body ◽  
Control Group ◽  
Before And After

Subject. Removable dentures have a negative impact on supporting tissues, biochemical parameters and composition of the microflora of the oral cavity, secretory activity of the salivary glands and other processes of the maxillofacial region and the body as a whole. One of the methods that can be used in the treatment and prevention of prosthetic stomatitis is balneotherapy. In the article, using the clinical, biochemical, microbiological and histological methods, the effectiveness of the use of mineral water "Fateevskaya" in patients using removable orthopedic structures was studied. Objectives of the study was to evaluate the effectiveness of procedures for small balneotherapy with the use of mineral water "Fateevskaya" in patients with removable dentures. Methods.We examined 158 elderly and senile age patients with removable dentures. Correction of removable dentures was carried out to all patients at the initial stage. All examined patients are divided into two groups. The group received the treatment with the low balneotherapy with “Fateevskaya” mineral water (78 patients, and the clinical control group (80 patients). The clinical condition of oral cavity was assessed before and after the course of low balneotherapy. Were researched: changes of mucous membrane of prosthetic bed, salivation rates, disturbance of salivary secretion, oral microbiocenosis. Results.Of the research showed that in both groups were increase of pH value, appears lower values of total protein and glucose, decrease in activity of some enzymes. This explanation is due to a decrease in the stress response to using the removable dentures, normalization of salivary glands functioning, decrease in the intensity of the phlogiston process. The results of a histological research also confirm this. The results of microbiological crops before and after the low balneotherapy indicate the oral biocenosis normalization. The positive changes in the researched parameters had significantly larger statistically valid values in the group received the treatment with the low balneotherapy with “Fateevskaya” mineral water. The results of the complex research allow us to recommend the “Fateevskaya” mineral water to low balneotherapy in dental practice.

scholarly journals Clinical symptoms of damage to the lateral surface of the tibia of dairy cows of different phenotype in the conditions of industrial dairy production

2020 ◽  
Vol 22 (100) ◽  
pp. 3-10
Author(s):  
L. Roman ◽  
S. Sidashova ◽  
I. Popova ◽  
N. Stepanova ◽  
V. Chornyi ◽  
...  
Keyword(s):  
Dairy Cows ◽  
Body Surface ◽  
Lateral Surface ◽  
Clinical Symptoms ◽  
Negative Impact ◽  
Skin Pigmentation ◽  
The Body ◽  
Lactating Cows ◽  
Red Hair ◽  
Service Period

The results of the influence of the conditions of keeping Ukrainian red dairy cows on the manifestation of clinical symptoms of damage to the lateral surface of the tibia and the level of reproduction are presented. The study was conducted on the basis of an industrial dairy complex (600 dairy cows with an average productivity of 6050 kg of milk per lactation) as part of agricultural associations in Odessa region. The objects of the study were cows during lactation, which were kept loose in sections with rest boxes (where the floor was a special rubber mat with a thickness of 30 mm). Evaluation (in points) was performed on the clinical manifestation of symptoms of damage to the skin epithelium of the lateral surface of the leg, which was injured by the rubber coating of the stall compared to the level of reproduction (service period, days/%) and the severity of skin pigmentation of the body surface (selection melanism). Clinical, zootechnical, biometric methods were comprehensively applied to realize the purpose of research. Comparison of data (n = 462) visual-clinical assessment of the condition of the skin of the lateral surface of the leg, as an indicator of the adaptability of lactating cows to keep in sections with rubber flooring and the area of pigmented hair of animals of different phenotypes by coat color, showed that cows typical pigmentation, characteristic of red dairy breed (red hair occupied more than 80 % of the body surface), wound lesions of the lower leg are much less common, namely: in comparison with red-spotted animals by 28.41–15.98 %, with mostly white – by 39.03–20.23 %, respectively. Due to the negative impact of open wounds of the skin of the leg on the immunity of lactating cows, it was found that increasing the number of animals with damaged epithelium as a gateway to infection, provokes an increase in the service period in cows with predominantly white or mottled color to 140.97 and 141.07 days, which is higher by 6.74 and 6.84 days, respectively, compared with red animals (P < 0.05).

About early diagnosis of vitamin deficiency

1937 ◽  
Vol 33 (2) ◽  
pp. 121-126
Author(s):  
E. M. Lepsky
Keyword(s):  
Vitamin A ◽  
Clinical Symptoms ◽  
Vitamin A Deficiency ◽  
Physiological Role ◽  
Vitamin Deficiency ◽  
The Body ◽  
Vitamin Deficiencies ◽  
Complete Diet ◽  
Digestive Disorders

In the expressed form of avitaminosis, we are now observed less and less. Nevertheless, the problem of vitamin deficiencies remains relevant for the practitioner. As the physiological role of vitamins and their importance in pathology becomes more and more clear, the presence of light, "erased" forms, which are more correctly called hypovitaminosis, becomes more and more obvious. Experience shows that the generally accepted ideas about the conditions for the occurrence of avitaminosis should be revised. Not only in the absence or in the absence of one or another vitamin in food, vitamin deficiency can develop. More and more observations are accumulating showing that a weak or even strongly pronounced vitamin deficiency can appear in a person who receives a completely complete diet. This phenomenon, paradoxical at first glance, can take place under the following circumstances: with digestive disorders associated with impaired absorption; with liver diseases (the latter is especially important for vitamin A deficiency, since the conversion of carotene into vitamin A suffers); when the need for vitamins is increased against the norm, for example, in rapidly growing children or in lactating women who excrete significant amounts of vitamin C with milk; with increased destruction of vitamin stores in the body, which is observed with all kinds of infections and other febrile and debilitating diseases. To what has been said, it must also be added that very often our food turns out to be poor in vitamins, due to irrational preparation, improper storage of food, peculiar deviations of appetite, etc. In the earliest stages, when even mild clinical symptoms do not yet exist, modern methods of studying vitamins can the presence of latent hypovitaminosis. This is especially evident in the example of the scourge.

scholarly journals Awareness of students on problems related to using of mobile phones

2020 ◽  
Vol 5 (1) ◽  
pp. 35-42
Author(s):  
Solomiya Pysarevska ◽  
◽  
Victoriya Vaschuk ◽  
Zinoviy Yaremko ◽  
◽  
...  
Keyword(s):  
Young People ◽  
Mobile Phone ◽  
Mobile Phones ◽  
Human Body ◽  
Information Technologies ◽  
Negative Impact ◽  
The Body ◽  
Security Measures ◽  
Human Environment ◽  
Level Of Knowledge

The article analyzes how young people adhere to the axiomatic rule of life safety, which should be treated as the most dangerous factor in the use of mobile devices of modern information technologies with a factor whose influence on the human body is not established. As the first step to avoiding the undesirable effects of any potential dangers is to realize their presence in the human environment, so the purpose of this study is to find out what is the attitude of young people, including students, to the use of mobile phones and whether they comply with basic security measures. to minimize potential negative impact. The object of the study is the prerequisites for the formation of smartphone dependency in young people and awareness of the potential dangers of mobile use. The results of the study of the age at which students started using a mobile phone and the frequency of its use for various purposes revealed possible signs of development in students of smartphone dependence. This is evidenced by the high percentage of those who received a cellphone for use early (50–60% between 9–12 years old) and the almost constant use of half of the students surveyed. Because the earlier a mobile phone is used, the more adverse its effect on the human body, since children are more susceptible to electromagnetic radiation than adults. According to the survey, 30–40% of students began to actively use a mobile phone at a fairly early age – 6–8 years. It has been found that students are not aware of the potential dangers of using mobile phones. This is confirmed by the students' low level of knowledge and interest in the indicators that characterize phone security; a small proportion of those who consider the safety of the phone when choosing a mark and model along with other features; as well as a significant percentage of students who do not adhere to safety measures, including increasing the distance from the body while storing a mobile phone

scholarly journals Expression of saliva biomarkers in patients with squamous cell carcinoma in various regions of the oral mucosa

2021 ◽  
Vol 25 (1) ◽  
pp. 29-34
Author(s):  
Ekaterina V. Kochurova ◽  
Vladimir N. Nikolenko ◽  
Olga I. Panferova ◽  
Ekaterina V. Izhnina ◽  
Ekaterina O. Kudasova ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Oral Mucosa ◽  
Squamous Cell ◽  
Oral Fluid ◽  
Pathological Process ◽  
The Body ◽  
Blood Analysis ◽  
Somatic Status

BACKGROUND: Oral fluid as a means for early detection and differential diagnosis of diseases of the oral mucosa and for assessing the overall somatic status of the body attracts the attention of researchers due to the non-invasiveness of material sampling and the exclusion of risks possible during blood analysis, as well as a simpler, compared with blood samples, material storage regime. AIM: The study aimed to evaluate the levels of oral fluid biomarkers of 170 patients with squamous cell carcinoma of the oral mucosa (RCC-MOP) depending on the localization of the oncopathology. MATERIALS AND METHODS: This study analyzed the levels of oral fluid biomarkers of 170 patients with RCC-MOP depending on the localization of oncopathology. Matrix metalloproteinases (MMPs) 2, 8, and 9, as well as their tissue inhibitors (TIMPs) 1 and 2, were chosen as biomarkers. For a comparative analysis, lesions of the tongue, cheek, floor of the oral cavity, alveolar ridge of the jaw, and oropharynx were selected. RESULTS: The study showed significant differences in the biomarker levels in the localization of squamous cell carcinoma in different parts of the oral mucosa. CONCLUSIONS: Analysis of the expression of oral fluid biomarkers with RCC-MOP revealed a link between the localization of the oncopathology and the level of synthesized biomarkers. The peak values of MMPs in the lesions of the tongue and floor of the oral cavity may be associated with the high number of salivary glands in these anatomical areas. The expression level is influenced by a number of factors, such as the localization of the pathological process, dental status, age, gender, and general condition of the patient.

scholarly journals VITAMIN DEFICIENCY AND FOOD SUPPLEMENTS

2021 ◽  
Vol 9 (12) ◽  
pp. 540-552
Author(s):  
Saad Fahad Aldaihani
Keyword(s):  
Vitamin B12 ◽  
Human Body ◽  
Vitamin B12 Deficiency ◽  
Vitamin Deficiency ◽  
Megaloblastic Anaemia ◽  
Water Soluble ◽  
Vitamin B ◽  
B12 Deficiency ◽  
And Function ◽  
Harmful Effects

Vitamins are a heterogeneous group of organic compounds that help ensure the human bodys wellbeing and function. This paper introduces the importance of all vitamins, both water-soluble and fat-soluble, as well as problems deriving from their deficiency. Additionally, vitamin supplements as part of treating vitamin deficiency, and possible harmful effects on the human body areshowcased. The main focus of the paper is on the vitamin B complex, and vitamin B12 specifically. The benefits of vitamin B12, as well as its action in the human body and the noxious effects of any lack of vitamin B12 in the human body, are also discussed. Some of the health conditionsan individual may need to face when they have vitamin B12 deficiency include neural tube defects, Alzheimers disease, depression, and megaloblastic anaemia, which are also introduced and further discussed, in terms of symptomatology, causes and suggested treatment. The toxicity of vitamin B12 is also introduced, and possible causes for vitamin B12 deficiency are showcased.

scholarly journals Role of Bacterial Flora in Oral Cancer- An Insight

2021 ◽  
Author(s):  
R Ananthalakshmi ◽  
M Priya ◽  
Nadeem Jeddy ◽  
LJ Sailakshmi
Keyword(s):  
Oral Cavity ◽  
Human Body ◽  
Bacterial Species ◽  
Bacterial Flora ◽  
Fungal Species ◽  
The Body ◽  
Oral Carcinoma ◽  
Oral Diseases ◽  
Organ Systems

The human body contains about 1014 bacteria which usually colonise different parts of the body. The bacterial flora is important for a person’s health as well as normal functioning of tissue and organ systems. Bacteria are single celled organisms and are found on almost all surfaces of human body. They act in synergy with host immune mechanism and provide protection against various undesirable foreign invasions, especially in the oral cavity, where they exist in a diversified form which survive in a symbiotic relationship with the host. When there is a disturbance in this equilibrium due to various factors like trauma or tobacco smoking, betel nut chewing and alcohol intake, which makes the mucous membrane more permeable to invading microorganisms, these commensal bacterial species can become virulent and give rise to oral diseases ranging from dental caries to oral carcinoma. The effects of these bacteria can be either direct or indirect initiation of chronic inflammation, formation of procarcinogens that contribute to the development of oral carcinoma. This article focuses on the role of oral bacterial flora in initiation and progression of oral carcinogenesis. Various bacterial and fungal species associated with oral carcinoma and predominant bacterial species in oral cavity and oropharyngeal region along with measures to prevent their adverse effects are described.

scholarly journals PSYCHOSOMATIC ASPECTS OF THE COMBINED PATHOLOGY OF PERIODONTAL TISSUE AND ORAL MUCOSA

2018 ◽  
pp. 32-34 ◽  
Author(s):  
T.A. Petrushanko ◽  
N.N. Ilenko
Keyword(s):  
Oral Cavity ◽  
Oral Mucosa ◽  
The Body ◽  
Psychological Characteristics ◽  
Control Group ◽  
Periodontal Tissue ◽  
Dental Patients ◽  
Periodontal Tissues ◽  
Experimental Group

In the structure of modern diseases, there are 50-75% of psychosomatic diseases. To understand the role of the emotional factor in the onset and progression of somatic disorders, as well as the opposite process – the emergence of psychological and emotional disorders as a response to an acute or chronic disease of internal organs – acquires a particular importance and relevance at the present stage of the causality of the disease. Individual features of the response of the human body to social, biological factors have common mechanisms of combined damage to the mucous membrane of the oral cavity and periodontal tissue. The severity of the damage to these organs and tissues is also determined by the psychological characteristics of individuals. These points are important not only for understanding the causality of the combined pathology of the periodontal and oral mucosa, but also for choosing the optimal tactics for treating such dental patients. The aim of the work was to analyze the role of psychosomatic correlations in the occurrence and development of the combined pathology of the periodontal and oral mucosa, determining the tactics of their treatment. 32 patients were involved in the examination with pathological changes of periodontal and oral mucosa. The essential role of the emotional component in the genesis of diseases was confirmed. Taking into account the psychosomatic nature of the pathology in the experimental group of patients, recommendations were given on diet therapy, psychotherapy, autogenic training. General medical treatment for internists and dentists was maximally individualized, taking into account the psychological characteristics of the response to the disease, differentiated according to the nature of the existing diseases, severity, pathology. After 6 months of follow-up, a stable, reliable positive clinical result was obtained in all patients in the experimental group and in 64% in the control group. Accounting for the state of psychosomatic relationships in the mechanisms of origin, development, treatment of diseases is extremely important. This approach in the supervision of dental patients who have combined changes in periodontal tissues, the oral mucosa allows achieving positive results of treatment, both in relation to the condition of the oral cavity, and for the body as a whole.

scholarly journals CHANGES IN QUANTITATIVE AND QUALITATIVE PROPERTIES OF ORAL LIQUID DURING REPLACEMENT OF DENTAL DEFECTS IN PATIENTS WITH ISCHEMIC HEART DISEASE

2020 ◽  
pp. 64-69
Author(s):  
N.O. Riabushko
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Oral Cavity ◽  
Human Body ◽  
Oral Fluid ◽  
The Body ◽  
Effective Control ◽  
Internal Environment ◽  
Qualitative Properties ◽  
Diagnostic Capabilities

Abstract. In recent years, the attention of scientists to the study of the unique properties of saliva and related diagnostic capabilities has increased significantly. Many data on the function and composition of oral fluid in healthy people and in various somatic pathologies. The ducts of three pairs of large (parotid, mandibular, sublingual) and up to a thousand small salivary glands open into the oral cavity of an adult. The amount of saliva secreted per day depends on the nature of food, age and sex. But on average, an adult secretes 750-1500 ml of saliva per day. Upon entering the oral cavity, saliva mixes with leukocytes, microorganisms and their products, exfoliated epithelium of the oral mucosa, oral detritus, gingival fluid, food debris, toothpaste, bronchial and nasal secretions. The purpose of the study: to investigate changes in the quantitative and qualitative properties of oral fluid in the replacement of dentition defects in patients with coronary heart disease. Object and methods of research. Sources of domestic and foreign literature. Research results. Oral fluid is an integral liquid medium of the human body and the first biological fluid that connects the internal environment of the body with the external. The activity of more than 100 enzymes, which differ in the origin and performance of the function, is determined in human oral fluid [6]. Changes in the activity of oral enzymes due to direct exposure to metal ions, plastics and related pathology can lead to a weakening of protective, mineralizing, digestive and other properties, which harms not only the dental system but also the human body as a whole. It is established that due to changes in permeability in the conditions of stress pathology the dynamic balance of the main internal environment - blood is preserved. It is proved that changes in the biochemical composition of blood and saliva correlate with the severity and features of myocardial infarction. Therefore, due to recent research in biochemistry and dentistry, laboratory methods continue to be improved and introduced into clinical practice, which allow to diagnose somatic and dental diseases by studying the parameters of oral fluid, which significantly expands diagnostic capabilities and allows more effective control of patients with combined pathology. Thus, in recent years it has been proven that an important role in the development of coronary heart disease and vascular pathology belongs to homocysteine, which is an intermediate product of metabolic conversions of methionine to cysteine. In case of insufficient utilization, homocysteine ​​leaves the cells in the liquid environment of the body, performing thrombogenic and pro-inflammatory effects. One of the main indicators of the immunological state of oral fluid is cationic antimicrobial peptides, which are important components of the immune system of a wide range of organisms. They play a key role in providing the first line of defense for the microorganism against infection. NHP1-NHP3 contain only 30 amino acid residues. Defensins show their microbial properties in micromolar conferences. Each representative of NHP has its own characteristic antimicrobial specificity of these peptides to each other. Defensins have the ability to suppress viral infection. They are effective against DNA and RNA viruses. Defensins inhibit the replication of human immunodeficiency virus, have high activity against the herpes virus. Also, these peptides inhibit vesicular stomatitis virus, human cytomegalovirus, influenza virus, adenovirus, papillomavirus and others. Conclusion. With secondary adentia (regardless of size and location), the volume of oral fluid decreases and its microelement composition changes. In addition, the replacement of dentition defects with different types of dentures causes metabolic disorders associated with the activation of free radical oxidation of biomolecules.

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