scholarly journals Implication of Buteyko Breathing Technique in Asthmatic Population: A Literature Review

2021 ◽  
pp. 515-521
Author(s):  
Saloni Patil ◽  
P. Shilna Rani ◽  
K. U. Dhanesh Kumar
Keyword(s):  
Web Of Science ◽  
Medication Use ◽  
Primary Component ◽  
Experimental Medicine ◽  
Asthma Treatment ◽  
Drug Usage ◽  
Significant Difference ◽  
Breathing Retraining ◽  
Science And Research

Background: Complementary and experimental medicine is gaining interest in the treatment of asthma around the world. This study summarizes the literature on complementary and alternative medicine approaches that use breathing retraining, i.e Buteyko breathing technique (BBT) as a primary component. Aim: The aim of this research is to provide background for BBT, analyse the available evidence for its efficacy and evaluate the physiological framework behind it. Methods: The analysis of literature is carried out by studying papers from electronic databases such as Cochrane, Medline, Embase, AMED, PEDro, Google Scholar, Elsevier, APTA, Campbell, Web of Science, and Research Gate. Conclusion: Individual studies using BBT consistently showed a reduction in asthma medication use. In either of the BBT experiments, no significant difference in lung ability was found. BBT detractors argue that drug reduction can be due to the physicians' influence, which is difficult to determine. Longer follow-up is needed to show that the improvement in asthma treatment as measured by drug usage is sustained over a clinically appropriate time span.

Abstract TP150: Effects of Pre-existing Psychotropic Medication Use on a Cohort of Patients With Ischemic Stroke Outcome

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Dilip Jayaraman ◽  
Nils Henninger ◽  
Brian Silver ◽  
Majaz Moonis ◽  
Anthony Rothschild ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Psychotropic Medication ◽  
Medication Use ◽  
Female Gender ◽  
Control Group ◽  
Stroke Outcome ◽  
Stroke Registry ◽  
Post Stroke ◽  
Significant Difference

Background: Although SSRI use for ischemic stroke related motor recovery has been studied with mixed results, the effects of the pre-existing psychotropic medication use (PPMU), such as antidepressants, on a long-term ischemic stroke outcome is unknown. Objective: We sought to determine the prevalence of PPMU, and the clinical outcome in a cohort of patients presenting with acute ischemic strokes. Methods: We retrospectively analyzed 323 consecutive patients who presented with an acute ischemic stroke that were included in an institutional stroke registry between January 2015 and December 2017. Baseline characteristics, functional outcome measured by mRS, cardiovascular complications and death within 90 days and 365 days were recorded. The control was defined as a group of ischemic stroke patients that were not on psychotropic medications pre- and/or post-ischemic stroke. Results: The prevalence of PPMU in the studied cohort was 21.4% (69/323). The prevalence of female gender in PPMU was higher compared to the control and post stroke-psychotropic medication use groups (P<0.001), and the patients with PPMU had similar vascular risk factors compared to the control (NS), except for an increased presence of hyperlipidemia (68.1% vs. 57.5%, p<0.05). Among the patients with an available 90-day follow-up (n=175) and 365-day follow-up (n=246), there was no statistically significant difference in outcome events of MI, stroke, death, and dementia. The mRS was higher on PPMU and poststroke-psychotropic medication use groups compared to the control group within the 365-day follow-up (P=0.013). Conclusion: The prevalence of PPMU is common in ischemic stroke, and it is not associated with worsened post-stroke complications within 1 year.

A Retrospective Analysis of Cyclooxygenase-II Inhibitor Response Patterns

2002 ◽  
Vol 18 (6) ◽  
pp. 305-309
Author(s):  
Richard S Castaldo ◽  
Anthony Mato ◽  
Alan F Kaul ◽  
Heather Gorski ◽  
Ronald J Bosch
Keyword(s):  
Medication Use ◽  
Practice Setting ◽  
Response Patterns ◽  
Kaplan Meier ◽  
Significant Difference ◽  
Clinical Practice Setting ◽  
Record Review ◽  
Experienced Treatment ◽  
Retrospective Medical Record Review

Objective: To summarize responses to cyclooxygenase-II (COX-II) medication use and describe physicians' reasons for switching or discontinuing therapy in the management of osteoarthritis. Methods: This retrospective medical record review evaluated all patients in a private clinical practice setting with a diagnosis of osteoarthritis who had been prescribed the COX-II inhibitor rofecoxib. Results: Of 144 evaluable patients, 81 had previously experienced treatment failure with celecoxib. Sixty-three patients had received rofecoxib as their first COX-II agent. A total of 101 of 144 patients remained on rofecoxib through the time of follow up. Patients starting celecoxib as their first COX-II agent discontinued therapy significantly earlier than those initiating treatment with rofecoxib (p < 0.001). Kaplan–Meier estimates of the median time to discontinuation were 17 weeks for celecoxib and 45 weeks for rofecoxib. There was no significant difference in the time to discontinuation in the first 6 months of therapy with a second COX-II agent between the groups. Conclusions: The majority of patients demonstrating therapeutic failure with 1 COX-II inhibitor may successfully be treated with another COX-II agent.

scholarly journals Recovery in stroke patients treated with fluoxetine versus placebo: A pooled analysis of 7,165 patients

2021 ◽  
Author(s):  
Ahmed Elsnhory ◽  
Mohammed Tarek Hasan ◽  
AbdulRahman Ibrahim Hagrass ◽  
Ahmed Hanbal ◽  
Anas fathy ◽  
...  
Keyword(s):  
Randomized Clinical Trials ◽  
Web Of Science ◽  
Bone Fractures ◽  
Pooled Analysis ◽  
National Institutes Of Health ◽  
Stroke Patients ◽  
Nihss Score ◽  
Significant Difference ◽  
New Onset

Abstract Purpose We conducted this study to build clear evidence regarding the outcomes of recovery in stroke patients treated with fluoxetine versus placebo. Methods Seventeen randomized clinical trials were identified by searching PubMed, Cochrane, Scopus, and Web of Science until June 2021. Results Fluoxetine enhances the National Institutes of Health Stroke Scale (NIHSS) score [MD -0.67, 95% CI (-1.19 to -0.15), P = 0.01] and the Fugl-Meyer Motor Scale (FMMS) score [MD 17.36, 95% CI (12.12 to 22.61), P <0.00001] at three months follow up. However, the NIHSS score showed no significant difference between the two groups at two weeks [MD -0.32 ,95% CI (-0.72 to 0.07), p=0.11] or at six months [MD -0.17 ,95% CI (-0.47 to 0.14), p=0.29]. Fluoxetine and placebo-treated patients had the same overall impact on FMMS scores at one month [MD 7.77, 95% CI (-10.57 to 26.11), P = 0.41]. The fluoxetine had a higher risk of broken bone (RR = 2.30, 95% CI [1.59, 3.32], p < 0.001) and hyponatremia (RR = 2.12, 95% CI [1.19, 3.76], p= 0.01) with lower risk of new depression (RR = 0.72, 95% CI [0.61, 0.84], p< 0.001) in comparison to placebo. Conclusion The efficacy of fluoxetine on the NIHSS and FMMS is likely to take time to emerge and is expected to be transient. The BI score did not differ between the fluoxetine and placebo groups. The use of fluoxetine increased the incidence of hyponatremia and bone fractures while decreasing the risk of new-onset depression.

scholarly journals Static Progressive Orthoses for Elbow Contracture: A Systematic Review

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Bin Chen ◽  
Jianhua Lin ◽  
Lifen Liu ◽  
Wenxin Niu
Keyword(s):  
Range Of Motion ◽  
Web Of Science ◽  
Daily Activities ◽  
Cochrane Library ◽  
Narrative Synthesis ◽  
Randomized Controlled ◽  
Significant Difference ◽  
Randomized Control ◽  
Elbow Contracture

Background. As one of the most common musculoskeletal complications following trauma, elbow contracture is a frequent source of disabled daily activities. Conventional interventions are inadequate to provide favorable outcome. The static progressive orthoses are getting popular in the treatment of this problem.Objective. The purpose of this review was to assess the effectiveness of static progressive orthoses for elbow contracture.Methods. Literatures when written in English published during 1 January 1997 and 31 January 2017 were searched in the following databases: Web of Science, Cochrane Library, PubMed, and EBSCOhost. Articles are quality-assessed by two assessors, each article was summarized in evidence tables, and a narrative synthesis was also performed.Results. Ten clinical trials were included. The study design and outcome measures used varied. Significant immediate improvement in the range of motion was reported by all studies, and those effects were still significant at follow-up. No significant difference was shown between static progressive and dynamic orthoses for elbow contracture in one randomized control trial.Conclusions. Current low-quality evidence suggested that static progressive orthoses provided assistance for elbow contracture through improving range of motion. Further research is recommended using high-quality randomized controlled trials.

Medication-Associated Depression: A Two and One-Half Year Follow-up of a Community Sample

1989 ◽  
Vol 18 (3) ◽  
pp. 283-292 ◽  
Author(s):  
Robert A. Maricle ◽  
J. David Kinzie ◽  
Peter Lewinsohn
Keyword(s):  
Community Sample ◽  
Medication Use ◽  
Epidemiological Studies ◽  
Medical Illness ◽  
Clinical Practices ◽  
Significant Difference

A community sample of forty subjects (of a total of 5 0) were followed up an average of two and one-half years after a SADS/RDC diagnosis of depression. The group was composed of twenty-one subjects whose depressions were judged to be associated with a medical illness or medication use and nineteen without this association. There was no difference in outcome as measured by persistence or recurrence of depression when groups were defined by associated medical illness. There was a significant difference when groups were defined by association with medication use. Of the nine subjects whose depressions were associated with medication, six were still depressed at follow-up; all six had continued to use implicated “depressogenic” medications. The three who were not depressed at follow-up were no longer using the originally implicated medications. The use of depressogenic medication appears to influence the course and/or duration of depression and must be accounted for in epidemiological studies and clinical practices.

scholarly journals Do the patient education program and nurse-led telephone follow-up improve treatment adherence in hemodialysis patients? A randomized controlled trial

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Mansour Arad ◽  
Rasoul Goli ◽  
Naser Parizad ◽  
Davoud Vahabzadeh ◽  
Rahim Baghaei
Keyword(s):  
Patient Education ◽  
Education Program ◽  
Controlled Trial ◽  
Intervention Group ◽  
Medication Use ◽  
Four Dimensions ◽  
Patient Education Program ◽  
Significant Difference ◽  
The Mean

Abstract Background End-Stage Renal Disease (ESRD) is the final and permanent stage of Chronic Kidney Disease (CKD). Hemodialysis (HD) is the most common treatment for CKD. To have desirable therapeutic outcomes, patients have to adhere to a specific therapeutic regimen that reduces the hospitalization rate and side-effects of HD. The present study aimed to determine the effects of the patient education program and nurse-led telephone follow-up on adherence to the treatment in hemodialysis patients. Methods This is a randomized controlled trial in which a total of 66 patients were recruited using convenience sampling and then randomly assigned to two groups of control (n = 33) and intervention (n = 33). Data were collected using a demographic questionnaire, the laboratory results record sheet, and the End-Stage Renal Disease Adherence Questionnaire (ESRD-AQ), which included four dimensions of HD attendance, medication use, fluid restrictions, and diet recommendations. The intervention group received a patient education program and nurse-led follow-up services through telephone communication and the Short Message Service (SMS) for 3 months. All participants filled in the questionnaire before and after the intervention. Data were analyzed using IBM SPSS Statistics for Windows, version 25 (IBM Corp., Armonk, N.Y., USA). Results The results showed a significant difference in the mean scores of HD attendance, medication use, fluid restrictions, and diet recommendations between the two groups immediately, 1 month, and 3 months after the intervention (p < .001). The results also indicated a significant difference in the mean scores of four dimensions during the four-time points of measurement in the intervention group (P < 0.0005). Therefore, the level of treatment adherence in the intervention group was higher than in the control group. Moreover, there was a significant difference in the mean score of laboratory values between the two groups after the intervention, except for the level of serum sodium (P = 0.130). Conclusion Implementation of the patient education program and nurse-led follow-up can lead to better adherence to hemodialysis in four dimensions of HD attendance, medication use, fluid restrictions, and dietary recommendations in HD patients. Trial registration IRCT registration number: IRCT20190127042512N1; Registration date: 2020-09-12; Registration timing: retrospectively registered: Last update: 2020-09-12.

Relationship between Thyroglobulin and Tumor Detectabilily with Thallium-201 in Differentiated Thyroid Cancer

2000 ◽  
Vol 39 (01) ◽  
pp. 10-15 ◽  
Author(s):  
S. P. Müller ◽  
Ch. Reiners ◽  
A. Bockisch ◽  
Katja Brandt-Mainz
Keyword(s):  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Roc Analysis ◽  
Tsh Suppression ◽  
Significant Difference ◽  
Test Specificity ◽  
The Relationship ◽  
Tumor Scintigraphy ◽  
Tsh Stimulation

Summary Aim: Tumor scintigraphy with 201-TICI is an established diagnostic method in the follow-up of differentiated thyroid cancer. We investigated the relationship between thyroglobulin (Tg) level and tumor detectability. Subject and methods: We analyzed the scans of 122 patients (66 patients with proven tumor). The patient population was divided into groups with Tg above (N = 33) and below (N = 33) 5 ng/ml under TSH suppression or above (N = 33) and below (N = 33) 50 ng/ml under TSH stimulation. Tumor detectability was compared by ROC-analysis (True-Positive-Fraction test, specificity 90%). Results: There was no significant difference (sensitivity 75% versus 64%; p = 0.55) for patients above and below 5 ng/ml under TSH suppression and a just significant difference (sensitivity 80% versus 58%; p = 0.04) for patients above and below 50 ng/ml under TSH stimulation. In 18 patients from our sample with tumor, Tg under TSH suppression was negative, but 201-TICI-scan was able to detect tumor in 12 patients. Conclusion: Our results demonstrate only a moderate dependence of tumor detectability on Tg level, probably without significant clinical relevance. Even in patients with slight Tg elevation 201-TICI scintigraphy is justified.

Melatih Kepemimpinan Perangkat Desa Kebonharjo Kulonprogo: Membangun Sikap Anti Korupsi

2018 ◽  
Vol 1 ◽  
pp. 107
Author(s):  
Adi Heryadi ◽  
Evianawati Evianawati
Keyword(s):  
Transformational Leadership ◽  
Data Collection ◽  
Paired Samples ◽  
Significant Difference ◽  
Before And After ◽  
Post Test ◽  
Sample Test ◽  
Corruption Perception ◽  
Measuring Tool

This study aims to prove whether transformational leadership training is effective for building anti-corruption attitudes of villages in Kebonharjo village, subdistrict Samigaluh Kulonprogo. This research is an experimental research with one group pre and posttest design.Subject design is 17 people from village of 21 candidates registered. Measuring tool used in this research is the scale of anti-corruption perception made by the researcher referring to the 9 anti-corruption values with the value of reliability coefficient of 0.871. The module used as an intervention made by the researcher refers to the transformational leadership dimension (Bass, 1990). The data collected is analyzed by statistical analysis of different test Paired Sample Test. Initial data collection results obtained sign value of 0.770 which means> 0.05 or no significant difference between anti-corruption perception score between before and after training. After a period of less than 1 (one) month then conducted again the measurement of follow-up of the study subjects in the measurement again using the scale of anti-corruption perception. The results of the second data collection were analysed with Paired Samples Test and obtained the value of 0.623 sign meaning p> 0.05 or no significant difference between post test data with follow-up data so that the hypothesis of this study was rejected.

The Effect of Odor and Color on Chemical Cooling

2019 ◽  
Author(s):  
Robert Pellegrino ◽  
Curtis Luckett
Keyword(s):  
Primary Component ◽  
Magnitude Scale ◽  
Trigeminal System ◽  
Abstract Concepts ◽  
Specific Chemical ◽  
Chemical Binding ◽  
Cooling Intensity ◽  
Crossmodal Associations ◽  
First Session

Chemesthesis, along with taste and olfaction, is a primary component of flavor that engages the trigeminal system through specific chemical binding. For instance, many gums or confectionaries incorporate chemical cooling agents, such as Wilkinson Sword (WS) compounds, to create the sensation of coldness. The current study was designed to evaluate crossmodal associations of color and aroma with the chemesthetic perception of cooling. A “minty” and non-odorized set of confectionary stimuli, colored green, blue or white, with moderate cooling properties (with WS-3) were used in this study. In the first session, participants were randomly presented a stimuli and asked to rate several attributes including its cooling intensity on a generalized Labeled Magnitude Scale (gLMS). In the second session, the same participants were asked to relate cooling levels to different colors and which color relates to the “minty” odor. Additionally, open-ended reasons were given for association choices. Appearance and odor influenced the intensity of cooling sensation. In particular, the odorized and blue samples were rated as cooler than the non-odorized and other colored samples, respectively. The follow-up session confirms blue as a color associated with cooling properties, especially cool objects/abstract concepts. Meanwhile, odor’s enhancement on cooling sensation may be more perceptual in nature through affective matching from enhanced flavor.

SUBLINGUAL VITAMIN D3 DRUG THERAPY IN VITAMIN D DEFICIENCY PATIENTS AT PRAVARA RURAL HOSPITAL

2019 ◽  
pp. 18-20
Author(s):  
Sanjeeva Kumar Goud T ◽  
Rahul Kunkulol
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Vitamin D3 ◽  
Serum Vitamin ◽  
Cross Sectional ◽  
Serum Vitamin D ◽  
Significant Difference ◽  
Before And After

The present study was aimed to study the effect of Sublingual Vitamin D3 on Serum Vitamin D level in Vitamin D deficiency patients. This was a cross-sectional and interventional study. All the Vitamin D deficiency patients of age 18-60years and either gender, willing to participate in the study were included. Patients who had greater than 20 ng/ml were excluded from the study. The total number of participants in our study was 200, out of these 111 males and 89 females, the mean age in our study was 51.07 ± 7.39Yrs. All volunteers were given sublingual vitamin D3 (60,000IU) in six doses every fifteen days of follow up for 3 months. The subject’s serum 25(OH)D levels were estimated before and after the treatment of sublingual vitamin D3. There was a statistically significant difference in serum vitamin D3 level before 16.61±6.71 ng/ml and after 35.80±7.80 ng/ml after treatment with Sublingual Vitamin D3. Six doses of 60,000IU of Vitamin D3 sublingual route having improved the role of serum 25(OH)D levels in the treatment of Vitamin D3 deficiency patients.Keywords: Vitamin D3; Sublingual route

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