Efforts to Improve Learning Motivation and Understanding in Early Children Through Serial Picture And Hand Puppet

The learning process that occurs at this time is not optimal. The provision of stimulation to improve children's development is carried out in a straightforward, general way, without enjoyable media stimulation. Students tend to be left to play alone in the schoolyard. It causes students to feel bored in following the lesson. This study aims to develop hand puppets and serial pictures as stimulation media for early childhood. This type of research is development. The research design used research development (R&D) about Borg and Gall with modified stages. The product test subjects studied were kindergarten students individually. The research data was collected using a questionnaire method, then the data collected was analyzed descriptively qualitatively concerning the theory of Miles and Huberman. The results of the media expert test on the five components/indicators rated for serial image media 89.2%, hand puppets 97.2%. The results of the material expert test on five elements/valuable indicators of hand puppets are 100%, and the picture series is 100%. Design expert test results obtained 93% for hand puppets and 80% for serial images. The percentage received shows that both media are feasible to be used to stimulate the growth and development of early childhood language skills. This research implies that teachers can apply the media of hand puppets and serial pictures to increase motivation and learning outcomes of early childhood.

PEMANFAATAN MEDIA GAMBAR BERSERI UNTUK MENINGKATKAN KETERAMPILAN MENULIS TEKS CERPEN MELALUI MODEL PEMBELAJARAN KREATIF PRODUKTIF

This study aims to describe the results of the ability to write short stories by utilizing serial image media through product creative learning models for class IX students at MTs Negeri 2 Banyumas. From the results of the initial conditions of learning to write short stories before using the media, it was found that the average ability of students in writing short stories was still far from the specified Minimum Completeness Criteria (KKM), which was a score of 72 and above. There are still many students who have not scored 72, which is 41.20%, while those who scored 72 and above are 58.22%. The inability of students to achieve this KKM requires an innovation, namely the use of serial image media through productive creative learning methods in learning to write short stories. So that there is an increase in the value of the results of writing short stories made by students using serial images, namely; the average ability to write short stories of students has increased from before when viewed from the percentage of previous learning outcomes, after using serial image media through productive creative learning methods, the results of learning to write short stories increased to 82.35%. From these results, it can be seen that there are still 17.65% of students who still get a score below 72, while others get a score of 72 and above. This proves that the use of serial image media through product creative learning methods can improve students' abilities in writing short stories. ABSTRAKPenelitian ini bertujuan untuk mendeskripsikan hasil kemampuan menulis teks cerpen dengan memanfaatkan media gambar berseri melalui model pembelajaran kreatif produk pada peserta didik kelas IX MTs Negeri 2 Banyumas. Dari hasil kondisi awal pembelajaran menulis teks cerpen sebelum menggunakan media ditemukan bahwa kemampuan rata-rata peserta didik dalam menulis cerpen masih jauh dari Kriteria Ketuntasan Minimum (KKM) yang ditetapkan, yaitu nilai 72 ke atas. Masih banyak peserta didik yang belum mendapat nilai 72 yaitu 41,20% sedangkan yang mendapat nilai 72 ke atas sebanyak 58,22%. Ketidakmampuan peserta didik dalam mencapai KKM ini membutuhkan sebuah inovasi, yaitu penggunaan media gambar berseri melalui metode pembelajaran kreatif produktif dalam pembelajaran menulis teks cerpen. Sehingga ada peningkatan nilai dari hasil menulis teks cerpen yang dibuat peserta didik dengan menggunakan media gambar berseri yaitu; rata-rata kemampuan menulis teks cerpen peserta didik sudah meningkat dari sebelumnya apabila dilihat dari prosentase hasil belajar sebelumnya, setelah menggunakan media gambar berseri melalui metode pembelajaran kreatif produktif hasil pembelajaran menulis teks cerpen meningkat menjadi 82,35%. Dari hasil tersebut dapat diketahui masih ada 17,65% peserta didik yang masih mendapatkan nilai di bawah 72, sedangkan lainnya mendapat nilai 72 ke atas. Hal ini membuktikan bahwa penggunaan media gambar berseri melalui metode pembelajaran kreatif produk dapat meningkatkan kemampuan peserta didik dalam menulis teks cerpen.

Initial Clinical Experience With a Simple, Home System for Early Detection and Monitoring of Diabetic Foot Ulcers: The Foot Selfie

Background: Diabetic foot ulcers (DFUs) are a leading cause of disability and morbidity. There is an unmet need for a simple, practical, home method to detect DFUs early and remotely monitor their healing. Method: We developed a simple, inexpensive, smartphone-based, “ Foot Selfie” system that enables patients to photograph the plantar surface of their feet without assistance and transmit images to a remote server. In a pilot study, patients from a limb-salvage clinic were asked to image their feet daily for six months and to evaluate the system by questionnaire at five time points. Transmitted results were reviewed weekly. Results: Fifteen patients (10 male) used the system after approximately 5 minutes of instruction. Participants uploaded images on a median of 76% of eligible study days. The system captured and transmitted diagnostic quality images of the entire plantar surface of both feet, permitting clinical-management decisions on a remote basis. We monitored 12 active wounds and 39 pre-ulcerative lesions (five wounds and 13 pre-ulcerative lesions at study outset); we observed healing of seven wounds and reversal of 20 pre-ulcerative lesions. Participants rated the system as useful, empowering, and preferable to their previous methods of foot screening. Conclusions: With minimal training, patients transmitted diagnostic-quality images from home on most days, allowing clinicians to review serial images. This system permits inexpensive home foot screening and monitoring of DFUs. Further studies are needed to determine whether it can reduce morbidity of DFUs and/or the associated cost of care. Artificial intelligence integration could improve scalability.

Design and 3D-printing of MRI-compatible cradle for imaging mouse tumors

Background The ability of 3D printing using plastics and resins that are magnetic resonance imaging (MRI) compatible provides opportunities to tailor design features to specific imaging needs. In this study an MRI compatible cradle was designed to fit the need for repeatable serial images of mice within a mouse specific low field MRI. Methods Several designs were reviewed which resulted in an open style stereotaxic cradle to fit within specific bore tolerances and allow maximum flexibility with interchangeable radiofrequency (RF) coils. CAD drawings were generated, cradle was printed and tested with phantom material and animals. Images were analyzed for quality and optimized using the new cradle. Testing with multiple phantoms was done to affirm that material choice did not create unwanted image artifact and to optimize imaging parameters. Once phantom testing was satisfied, mouse imaging began. Results The 3D printed cradle fit instrument tolerances, accommodated multiple coil configurations and physiological monitoring equipment, and allowed for improved image quality and reproducibility while also reducing overall imaging time and animal safety. Conclusions The generation of a 3D printed stereotaxic cradle was a low-cost option which functioned well for our laboratory.

New evidence of arsenic translocation and accumulation in Pteris vittata from real-time imaging using positron-emitting 74As tracer

Pteris vittata is an arsenic (As) hyperaccumulator plant that accumulates a large amount of As into fronds and rhizomes (around 16,000 mg/kg in both after 16 weeks hydroponic cultivation with 30 mg/L arsenate). However, the sequence of long-distance transport of As in this hyperaccumulator plant is unclear. In this study, we used a positron-emitting tracer imaging system (PETIS) for the first time to obtain noninvasive serial images of As behavior in living plants with positron-emitting 74As-labeled tracer. We found that As kept accumulating in rhizomes as in fronds of P. vittata, whereas As was retained in roots of a non-accumulator plant Arabidopsis thaliana. Autoradiograph results of As distribution in P. vittata showed that with low As exposure, As was predominantly accumulated in young fronds and the midrib and rachis of mature fronds. Under high As exposure, As accumulation shifted from young fronds to mature fronds, especially in the margin of pinna, which resulted in necrotic symptoms, turning the marginal color to gray and then brown. Our results indicated that the function of rhizomes in P. vittata was As accumulation and the regulation of As translocation to the mature fronds to protect the young fronds under high As exposure.

Three-dimensional imaging and reconstruction of the whole ovary and testis: a new frontier for the reproductive scientist

The 3D functional reconstruction of a whole organ or organism down to the single cell level and to the subcellular components and molecules is a major future scientific challenge. The recent convergence of advanced imaging techniques with an impressively increased computing power allowed early attempts to translate and combine 2D images and functional data to obtain in-silico organ 3D models. This review first describes the experimental pipeline required for organ 3D reconstruction: from the collection of 2D serial images obtained with light, confocal, light-sheet microscopy or tomography, followed by their registration, segmentation and subsequent 3D rendering. Then, we summarise the results of investigations performed so far by applying these 3D image analyses to the study of the female and male mammalian gonads. These studies highlight the importance of working towards a 3D in-silico model of the ovary and testis as a tool to gain insights into their biology during the phases of differentiation or adulthood, in normal or pathological conditions. Furthermore, the use of 3D imaging approaches opens to key technical improvements, ranging from image acquisition to optimisation and development of new processing tools, and unfolds novel possibilities for multidisciplinary research.

Discordance between central versus local response assessments in neuroendocrine tumor (NET) patients (pts) enrolled in A021202.

361 Background: Assessment of tumor response in extrapancreatic NETs with metastases can be very challenging. Previous studies suggest a high degree of discordance between local and central imaging reviews, which has implications for clinical practice and trial design. Methods: Serial images archived from a randomized phase II trial (A021202) of pazopanib vs placebo in progressive non-pancreatic NETs were evaluated by central review, with real-time review conducted at the time of locally interpreted progressive disease (PD). The primary endpoint of the trial was progression-free survival (PFS) by central review. Discordances between central (Alliance Imaging Core Laboratory) and local (investigator-reported) reviews were assessed. Scan-level and pt-level results across both treatment arms were evaluated. Kappa tests were used to test concordance based on source of review. Results: 151 pts had a total of 724 scans with response adjudication by both local and central RECIST review. Discordance was observed in both directions. Overall, 20% of scans (143/724) had discordant classifications. The most common discordances were: stable disease (SD) on local vs. PD on central review (82/143=57%), and PD on local vs. SD on central review (32/143=22%). On a pt level, 78 of 151 pts (52%) had discordant reviews; 8 had >1 type of discordance. Overall, 30% of pts (N=45) had a determination of PD on central review, but SD or better on local review, potentially resulting in excessive exposure to therapy. In contrast, 20% (N=30) were classified as PD on local read but SD or better on real-time central review (which did not necessarily translate into an abbreviated course of treatment). Cohen’s kappa statistics revealed only moderate concordance between local and central reviewers both at the scan (K=0.48, 95% CI: 0.42 – 0.55) and pt (K=0.41, 95% CI: 0.32 – 0.5) levels, with no significant influence by treatment arm, primary tumor site, tumor functionality, histology, differentiation or primary disease spread. Conclusions: Discordance was observed in both directions, where 30% of pts were potentially kept on study drug too long (based on central read), and 20% would have been taken off study treatment early for local PD were it not for real-time central review. Although this bidirectional discordance did not affect the overall findings of the PFS outcome between arms in the trial, these analyses highlight the high prevalence of discordance, the potential to negatively influence treatment duration in both directions, and the need for more straightforward methods of assessing treatment response in carcinoid. Support: U10CA180821, U10CA180882, U24CA196171; NETRF Investigator Award; https://acknowledgments.alliancefound.org Clinical trial information: NCT01841736.

تطبيق طريقة رتلّي ستوري بالرسوم المتسلسلة لترقية قدرة الطلبة على مهارة الكلام دراسة تجريبية بـــباب النجاح بندا أتشية

In the second language, speaking is a basic skill in learning language, because language it selft is speech, a person not considered of mastering the language except by mastering the speaking. The students of Babun Najah not only found difficult in speaking Arabic language but got borred as well. Thus, student had a very low ability. It was caused by the disagreement between method used by teacher and do not use the interesting media according to students’ condition, it makes the students felt bored, lack of attention to the subject; even some of them spoke during the teaching and learning process. So the learning process runs ineffectively. This resulted in the limit ability of students to speak Arabic. Based on this problem that has been studied by the researchers, so we need for solution to overcome these problems, including: applying the Retelling Story method with the serial images in teaching Arabic language to reach the purposes of teaching speaking skills, in hopes of increasing student ability in speaking skills by combining these two variables. The purposed of this research is to know students’ responses to speaking skills and students’ abilities in speaking Arabic language using the retelling method and serial pictures in Babun Najah Banda Aceh boarding school. Quantitative supported by qualitative approach along with experimental method was used by the researcher. Purposive sampling was used to find the second graders of II-C as a control class and II-D as an experimental class that was consisted of 23 students. The results are that students’ response toward Retelling story Method with the pictures series is well, and the use of Retelling story Method with the pictures series was effective and it gave a good impact on students of Babun Najah Banda Aceh boarding school, which the result from the t-test relate calculation is greater than t-table result, that is 1,69 < 1,93.