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Author(s):  
Jesús Arturo Sánchez-Sánchez ◽  
Montserrat Navarro-Espino ◽  
Yonatan Betancur Ocampo ◽  
José Eduardo Barrios Vargas ◽  
Thomas Stegmann

Abstract A nanoelectronic device made of twisted bilayer graphene (TBLG) is proposed to steer the direction of the current flow. The ballistic electron current, injected at one edge of the bottom layer, can be guided predominantly to one of the lateral edges of the top layer. The current is steered to the opposite lateral edge, if either the twist angle is reversed or the electrons are injected in the valence band instead of the conduction band, making it possible to control the current flow by electric gates. When both graphene layers are aligned, the current passes straight through the system without changing its initial direction. The observed steering angle exceeds well the twist angle and emerges for a broad range of experimentally accessible parameters. It is explained by the twist angle and the trigonal shape of the energy bands beyond the van Hove singularity due to the Moiré interference pattern. As the shape of the energy bands depends on the valley degree of freedom, the steered current is valley polarized. Our findings show how to control and manipulate the current flow in TBLG. Technologically, they are of relevance for applications in twistronics and valleytronics.


2021 ◽  
Vol 12 ◽  
Author(s):  
Alexander Castilla ◽  
Gregoire Borst ◽  
David Cohen ◽  
Jacques Fradin ◽  
Camille Lefrançois ◽  
...  

Classical neuropsychological assessments are designed to explore cognitive brain functions using paper-and-pencil or digital tests. The purpose of this study was to design and to test a new protocol named the “Virtual House Locomotor Maze” (VHLM) for studying inhibitory control as well as mental flexibility using a visuo-spatial locomotor memory test. The VHLM is a simple maze including six houses using the technology of the Virtual Carpet Paradigm™. Ten typical development children (TD) were enrolled in this study. The participants were instructed to reach a target house as quickly as possible and to bear in mind the experimental instructions. We examined their planning and replanning abilities to take the shortest path to reach a target house. In order to study the cognitive processes during navigation, we implemented a spatio-temporal index based on the measure of kinematics behaviors (i.e., trajectories, tangential velocity and head direction). Replanning was tested by first repeating a path chosen by the subject to reach a given house. After learning this path, it was blocked imposing that the subject inhibited the learned trajectory and designed a new trajectory to reach the same house. We measured the latency of the departure after the presentation of each house and the initial direction of the trajectory. The results suggest that several strategies are used by the subjects for replanning and our measures could be used as an index of impulsivity.


Symmetry ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1366
Author(s):  
Shanie A. L. Jayasinghe ◽  
Candice Maenza ◽  
David C. Good ◽  
Robert L. Sainburg

Typical upper limb-mediated activities of daily living involve coordination of both arms, often requiring distributed contributions to mechanically coupled tasks, such as stabilizing a loaf of bread with one hand while slicing with the other. We sought to examine whether mild paresis in one arm results in deficits in performance on a bilateral mechanically coupled task. We designed a virtual reality-based task requiring one hand to stabilize against a spring load that varies with displacement of the other arm. We recruited 15 chronic stroke survivors with mild hemiparesis and 7 age-matched neurologically intact adults. We found that stroke survivors produced less linear reaching movements and larger initial direction errors compared to controls (p < 0.05), and that contralesional hand performance was less linear than that of ipsilesional hand. We found a hand × group interaction (p < 0.05) for peak acceleration of the stabilizing hand, such that the dominant right hand of controls stabilized less effectively than the nondominant left hand while stroke survivors showed no differences between the hands. Our results indicate that chronic stroke survivors with mild hemiparesis show significant deficits in reaching aspects of bilateral coordination, but no deficits in stabilizing against a movement-dependent spring load in this task.


Author(s):  
Andrea M. Kuczynski ◽  
Adam Kirton ◽  
Jennifer A. Semrau ◽  
Sean P. Dukelow

Abstract Background Studies using clinical measures have suggested that proprioceptive dysfunction is related to motor impairment of the upper extremity following adult stroke. We used robotic technology and clinical measures to assess the relationship between position sense and reaching with the hemiparetic upper limb in children with perinatal stroke. Methods Prospective term-born children with magnetic resonance imaging-confirmed perinatal ischemic stroke and upper extremity deficits were recruited from a population-based cohort. Neurotypical controls were recruited from the community. Participants completed two tasks in the Kinarm robot: arm position-matching (three parameters: variability [Varxy], contraction/expansion [Areaxy], systematic spatial shift [Shiftxy]) and visually guided reaching (five parameters: posture speed [PS], reaction time [RT], initial direction error [IDE], speed maxima count [SMC], movement time [MT]). Additional clinical assessments of sensory (thumb localization test) and motor impairment (Assisting Hand Assessment, Chedoke-McMaster Stroke Assessment) were completed and compared to robotic measures. Results Forty-eight children with stroke (26 arterial, 22 venous, mean age: 12.0 ± 4.0 years) and 145 controls (mean age: 12.8 ± 3.9 years) completed both tasks. Position-matching performance in children with stroke did not correlate with performance on the visually guided reaching task. Robotic sensory and motor measures correlated with only some clinical tests. For example, AHA scores correlated with reaction time (R = − 0.61, p < 0.001), initial direction error (R = − 0.64, p < 0.001), and movement time (R = − 0.62, p < 0.001). Conclusions Robotic technology can quantify complex, discrete aspects of upper limb sensory and motor function in hemiparetic children. Robot-measured deficits in position sense and reaching with the contralesional limb appear to be relatively independent of each other and correlations for both with clinical measures are modest. Knowledge of the relationship between sensory and motor impairment may inform future rehabilitation strategies and improve outcomes for children with hemiparetic cerebral palsy.


2021 ◽  
Author(s):  
Yuhao Deng ◽  
Julan Xie ◽  
Zishu He ◽  
Jun Li

Abstract In this paper, a novel monopulse estimator is proposed to surmount obstacles caused by unknown polarized pattern and the difference among each dipole orientation. Polarized pattern often alters the phased array response and we could hardly recover it if we known nothing about polarized parameters. The sum and difference beamforming of conformal phased array is affected due to the difference among each dipole orientation. Therefore the conventional monopulse estimator is dumped in this circumstance. The method proposed in this paper is a remarkable estimator based on maximum likelihood methodology. In this method, polarized parameters are considered as a part of desired signal and the least-squares solution of desired signal is obtained. With the desired signal solution, the likelihood function with respect to direction is derived at first. Then from the above, Jacobian and Hessian matrix of likelihood function is deduced. The boresight is considered as the initial direction value and the estimator of desired signal direction is obtained by Newton's formula. Finally, the polarized parameters are estimated by least-squares method using the direction estimator. The root-mean-square error (RMSE) of angle estimation is acceptable when prior polarized information is completely unknown. Polarized parameters are estimated by similar technique after we find out azimuth and elevation. Our research fills a gap of monopulse estimation with arbitrary polarization and diverse dipole arrangement.


2020 ◽  
Vol 12 (19) ◽  
pp. 3134 ◽  
Author(s):  
Guanghui Hu ◽  
Wen Dai ◽  
Sijin Li ◽  
Liyang Xiong ◽  
Guoan Tang

Terrain derivatives exhibit surface morphology in various aspects. However, existing spatial change calculation methods for terrain derivatives are based on a mathematical scalar operating system, which may disregard the directional property of the original data to a certain extent. This situation is particularly true in second-order terrain derivatives, in which original data can be terrain derivatives with clear directional properties, such as slope or aspect. Thus, this study proposes a mathematical vector operation method for the calculation of second-order terrain derivatives. Given the examples of the first-order terrain derivatives of slope and aspect, their second-order terrain derivatives are calculated using the proposed vector method. Directional properties are considered and vectorized using the following steps: rotation-type judgment, standardization of initial direction, and vector representation. The proposed vector method is applied to one mathematical Gaussian surface and three different ground landform areas using digital elevation models (DEMs) with 5 and 1 m resolutions. Comparison analysis results between the vector and scalar methods show that the former achieves more reasonable and accurate second-order terrain derivatives than the latter. Moreover, the vector method avoids overexpression or even exaggeration errors. This vector operation concept and its expanded methods can be applied in calculating other terrain derivatives in geomorphometry.


ILR Review ◽  
2020 ◽  
pp. 001979392094276
Author(s):  
Jenna E. Myers ◽  
Katherine C. Kellogg

Using a 20-month qualitative study of four US states that implemented career pathways spanning from high schools to colleges to employers, the authors illustrate the potential for state government actors to facilitate coordination of workforce development systems across geographies and industries. As a complement to explanations situated in workforce intermediary practices or formal state policies, the authors show that state actors can address barriers to coordination by using state actor orchestration—structuring provisional goal setting and revision, encouraging experimentation, and framing coordination to inspire collective action. This approach involves three types of practices: structural (building statewide governance structures and modifying governance processes), political (providing initial direction and piloting and broadening the set of stakeholders), and cultural (identifying key problems and collective action solutions and building social accountability for new roles). These practices vary according to states’ institutional environments: Where governance is more centralized, state actors gain latitude to guide regional workforce development.


Cells ◽  
2020 ◽  
Vol 9 (6) ◽  
pp. 1493 ◽  
Author(s):  
Julia Bindl ◽  
Eszter Sarolta Molnar ◽  
Mary Ecke ◽  
Jana Prassler ◽  
Annette Müller-Taubenberger ◽  
...  

Multinucleate cells can be produced in Dictyostelium by electric pulse-induced fusion. In these cells, unilateral cleavage furrows are formed at spaces between areas that are controlled by aster microtubules. A peculiarity of unilateral cleavage furrows is their propensity to join laterally with other furrows into rings to form constrictions. This means cytokinesis is biphasic in multinucleate cells, the final abscission of daughter cells being independent of the initial direction of furrow progression. Myosin-II and the actin filament cross-linking protein cortexillin accumulate in unilateral furrows, as they do in the normal cleavage furrows of mononucleate cells. In a myosin-II-null background, multinucleate or mononucleate cells were produced by cultivation either in suspension or on an adhesive substrate. Myosin-II is not essential for cytokinesis either in mononucleate or in multinucleate cells but stabilizes and confines the position of the cleavage furrows. In fused wild-type cells, unilateral furrows ingress with an average velocity of 1.7 µm × min−1, with no appreciable decrease of velocity in the course of ingression. In multinucleate myosin-II-null cells, some of the furrows stop growing, thus leaving space for the extensive broadening of the few remaining furrows.


Sensors ◽  
2020 ◽  
Vol 20 (6) ◽  
pp. 1629
Author(s):  
Jinqing Shen ◽  
Yi He ◽  
Jianfeng Li

While the coprime array still suffers from performance degradation due to the mutual coupling dominated by the interleaved subarrays, we propose an array switching strategy for coprime linear array (CLA) by utilizing the large inter-element spacings of the subarrays to mitigate the mutual coupling. Specifically, we first collect the signals by separately activating the two subarrays, where the severe mutual coupling effect is significantly reduced. As a result, well-performed initial direction of arrival (DOA) estimates can be achieved. Subsequently, we establish a quadratic optimization problem by reconstructing the contaminated steering vector of the total CLA elaborately to calculate the mutual coupling coefficients with the initial DOA estimates. Finally, we can obtain refined DOA estimates by an iteration procedure based on the estimated mutual coupling matrix. In addition, numerical simulations are provided to demonstrate the merits of the proposed scheme.


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