The human society is permanently changing in all aspects. It has experienced many challenges like wars, political conflicts, and financial systems collapse. Today it is hurt by an old well-known enemy – the pandemic. In order to make the things better and even to survive current society is investing in market, production, communications and technological progress. The common base of all these fields is the digitalization on the Communication and Information Technology (IT – Hardware, Software, Algorithms, and Methods). Since the 50-ies of the 20th Century the IT is in permanent development but this has not impacted all layers of the society. In the last decade it is observed a new trend. The IT impacts almost all layers and the technologies of the society – communications, productions, management, analysis, forecasts, education, health, social and medical security). This chapter is concentrated on the basics and tools of digital transformation of business and trends in the business and production in the frame of this new paradigm.