Bifurcation functional significance score as predictor of mortality: a validating study

Considerable progress has been made in the treatment of coronary bifurcation stenosis. Anatomical characteristics of the vessel and lesion, however, fail to give information about the functional significance of the bifurcation stenosis. To the best of our knowledge, there is no study that systematically establishes the baseline functional significance of coronary stenosis and its effect on procedural and clinical outcomes. Patients with significant angiographic bifurcation lesions defined as diameter stenosis > 50% in main vessel and/or side branch were included. FFR was performed in main vessel (MV) and side branch (SB) before and after percutaneous coronary intervention (PCI). 169 patients from Fiesta study (derivation cohort) and 555 patients from prospective bifurcation registry (clinical effect cohort) were analyzed to validate angiographic prediction score (BFSS) used to determine the potentially functional significance of coronary bifurcation stenosis. Bifurcation functional significance score (including the following parameters—SYNTAX ≥ 11, SB/MB BARI score, MV %DS ≥ 55%, main branch (MB) %DS ≥ 65%, lesion length ≥ 25 mm) with a maximum value of 11 was developed. A cut-off value of 6.0 was shown to give the best discriminatory ability—with accuracy 87% (sensitivity 77%, specificity 96%, p < 0.001). There was also a significant difference in all-cause mortality between patients with BFSS ≥ 6.0 vs. BFSS < 6.0–25.5% vs. 18.4%, log-rank p = 0.001 as well as cardiac mortality: BFSS ≥ 6.0 vs. BFSS < 6.0–17.7% vs. 14.5%, log-rank (p = 0.016). The cardiac mortality was significantly lower in patients with smaller absolute SB territory, p = 0.023. An angiographic score (BFSS) with good discriminatory ability to determine the functional significance of coronary bifurcation stenosis was developed. The value for BFSS ≥ 6.0 can be used as a discriminator to define groups with higher risk for all-cause and cardiac mortality. Also, we found that the smaller side branches pose greater mortality risk.

influence of environmental psychoeducation on children's empathy skill in community reading park

This research aimed to compare the empathy ability of children before and after acquiring the community-based psychoeducation with pro-green activities designed for environment conservation. This research used a quantitative design with Quasi Experiment: One Group Pretest-Posttest Design as the research design. The participants were 34 children with age 8 until 12 years old. This research used purposive sampling with the criteria such as 1) The children from Dusun Jayan, Desa Senting, Boyolali Regency, and 2) Age 8 until 12 years old. The results showed that the mean score before the activity was 70,62 and after the activity was 74,32. There was an increase score 3,7 with the significance score (Sig.2-tailed) of 0.035 (p<0,05) and t-value = -2,194. Conclusion: 1). There was a positive significance between environment psychoeducation and children's empathy ability, and 2) The environment psychoeducation was effective to increase children's ability who play and learn at Taman Baca Masyarakat Panggon Sinau.

Pelatihan Resiliensi Untuk Menurunkan Perceived Stress Selama Masa Pandemi Covid-19

The COVID-19 pandemic that its first case in Indonesia found in March 2020 urged society to adapt to a new lifestyle. Offline meetings were restricted to avoid the transmission of COVID-19, therefore, online meetings have become a new lifestyle presently. This process of adapting to online’s lifestyle happens universally in such workplaces and educational institutions of kindergartens to colleges. This sudden adaptation makes society experience some pressure which also affects an individual’s stress and wellbeing. Teachers at one of the special needs schools in Sidoarjo, Indonesia, experience stress due to the pressures they had while adapting to online teachings. Resilience training is given as an intervention to help teachers decrease their level of stress. The training is scheduled for 3 (three) days and holds 6 (six) sessions via Zoom Meeting. The data result is analyzed using Wilcoxon differentiate test for resilience and perceived stress scores before and after the training. The result shows a difference between resilience and perceived stress scores before and after the training session with a significance score of 0,005 (p<0,05). This result concludes that resilience training can decrease the level of perceived stress that the teachers experienced.

TAʾṮĪR QIRĀʾAH AL-MURABBAʿI FĪ TAʿLĪM AL-QIRĀʾAH

The aims of this research are: To study how to apply and influence the strategy of square or text cut and Broken Square / Text & Index Card Match for Islamic high school students in Balangan.The research design used in this study was an experimental research design.The results of this study are 1) during the implementation of the Broken Square / Text & Index Card Match strategy, it can be seen that there is a change in the learning patterns of students who answer the questions asked by the researcher, in addition, they are also more enthusiastic and active in working on the assigned task. Poor activity also tends to decrease and 2) the effect on learning outcomes is found by students about Broken Square / Text & Index Card Match at Madrasah Tsanawiyah Negeri 3 Balangan and Madrasah Tsanawiyah Al Hidayah Inan Paringin Selatan according to the test results was 0.00 is smaller than the significance score α = 0.05, this indicates that Ha is accepted and H0 is rejected.

Bifurcation Functional Significance Score as Predictor of Mortality

Background: Considerable progress has been made in the treatment of coronary bifurcation stenosis. Anatomical characteristics of the vessel and lesion, however, fail to give information about the functional significance of the bifurcation stenosis. To the best of our knowledge, there is no study that systematically establishes the baseline functional significance of coronary stenosis and its effect on procedural and clinical outcomes.Methods: Patients with significant angiographic bifurcation lesions defined as diameter stenosis > 50% in main vessel and/or side branch were included. FFR was performed in main vessel (MV) and side branch (SB) before and after percutaneous coronary intervention (PCI). 169 patients from Fiesta study (derivation cohort) and 555 patients from prospective bifurcation registry (test cohort) were analyzed to validate angiographic prediction score (BFSS) used to determine the potentially functional significance of coronary bifurcation stenosis.Results: Bifurcation functional significance score (including the following parameters - SYNTAX ≥11, SB/MB BARI score, MV %DS ≥ 55%, MB %DS ≥ 65%, lesion length ≥25mm) with a maximum value of 11 was developed. A cut-off value of 8.5 was shown to give the best discriminatory ability – with accuracy 87% (sensitivity 77%, specificity 96%, p<.001). There was also a significant difference in all-cause mortality between patients with BFSS≥8.5 vs. BFSS<8.5 – 17.8% vs. 13.4%, log-rank p=.006, as well as cardiac mortality: BFSS≥8.5 vs. BFSS<8.5 – 14.6% vs. 12.5%, log-rank (p=.042). The cardiac mortality was significantly lower in patients with smaller absolute SB territory, p=0.023.Conclusion: An angiographic score (BFSS) with good discriminatory ability to determine the functional significance of coronary bifurcation stenosis was developed. The value for BFSS≥8.5 can be used as a discriminator to define groups with higher risk for all-cause and cardiac mortality. Also, we found that the smaller side branches pose greater mortality risk.

THE EFEKTIVITAS PENGGUNAAN MEDIA BALOK CUISENAIRE TERHADAP KEMAMPUAN MENGENAL KONSEP LAMBANG BILANGAN PADA ANAK USIA 4-5 TAHUN

Pengenalan konsep lambang bilangan pada anak usia 4-5 tahun atau anak TK kelompok A harus diiringi dengan benda konkrit atau nyata agar potensi yang mereka miliki dapat berkembang secara optimal. Tujuan penelitian ini adalah untuk mengetahui efektivitas penerapan Balok Cuisenaire terhadap kemampuan mengenal konsep lambang bilangan terhadap anak usia 4-5 tahun dalam kegiatan pembelajaran. Penelitian ini merupakan penelitian kuasi eksperimen yang berbentuk nonequivalent control grup design. Penelitian dilaksanakan selama satu bulan dengan 6 kali pertemuan pada setiap kelompok. Teknik pengambilan sampel yang digunakan adalah sampel bertujuan. Penelitian dilaksanakan di sebuah taman kanak-kanak di Kota Surakarta. Partisipan penelitian ini adalah kelompok eksperimen berjumlah 21 anak dan kelompok kontrol berjumlah 21 anak. Analisis data terdiri dari uji prasyarat dan uji hipotesis. Hasil uji prasyarat menggunakan Shapiro Wilk dan Levene Test for Equality of Variance yang menunjukkan bahwa data bersifat normal dan homogen. Sedangkan pada uji hipotesis menggunakan paired sample t-test untuk uji pre-post dalam kelompok yang sama dan independent sample t-test untuk uji beda antar kelompok dengan membandingkan skor kelompok kontrol dengan eksperimen pada signifikasi p < 0,05. Hasil penelitian menunjukkan rata-rata pretest kelompok eksperimen dan kontrol adalah 16,05 dan 15,90 dengan nilai signifikansi 0,758. Sedangkan rata-rata posttest kelompok eksperimen dan kontrol adalah 22,29 dan 16,33 dengan nilai signifikansi 0,000. Nilai signifikansi posttest kelompok eksperimen dan kontrol 0,000 ≤ 0,05 sehingga dapat disimpulkan bahwa terdapat efektivitas penggunaan media balok Cuisenaire terhadap perkembangan mengenal konsep lambang bilangan pada anak usia 4-5 tahun. The introduction of the concept of number symbols in children aged 4-5 years or kindergarten children group A must be accompanied by concrete or tangible objects so that their potential can develop optimally. The purpose of this study is to find out the effectiveness of the application of Cuisenaire Blocks to the ability to recognize the concept of number symbols to children aged 4-5 years in learning activities. This research is a quasi-experimental study in the form of a nonequivalent control group design. In this research, each group conducts six meetings each month. The sampling technique used is purposive sampling. Participants in this study were an experimental and control group, both consists of 21 children. Data analysis consists of prerequisite and hypothesis tests. The prerequisite test results using Shapiro Wilk and the Levene Test for Equality of Variance showed that the data was usual and homogeneous. While in the hypothesis test using paired sample t-test for pre-post test in the same group and independent sample t-test for different tests between groups by comparing the score of the control and experiment groups on signification p < 0.05. The results showed that the average pretest of the experiment and control group was 16.05 and 15.90, with a significance score of 0.758. Meanwhile, the average posttest of the experiment and control group was 22.29 and 16.33, with a significance score of 0.000. Based on the experiment and control group significance score of 0.000 ≤ 0.05, this research concluded that Cuisenaire block media usage develops the concept of number symbols recognition ability in children aged 4-5.

The influence of using podcast toward listening comprehension

Listening is an individual concentration on specific aspects of aural information, build context from passages, and connect what they hear to prior experience. Unfortunately, listening activities are rarely given to students. The problem is formulated as follow: “Is there any significant difference of using video podcast toward listening comprehension of students majoring in Multimedia at the first grade of SMK 4 Metro?”.The research design was quasi-experimental. The students Majoring in Multimedia at first grade SMK 4 Metro as population. To assess the students’ listening comprehension, the researcher used a written test. Based on the result, the significance score of 0.002 was smaller than t table 0.05, which meant that Ha was accepted and there was a significant difference between students who taught by using podcast and those who were not. As a result, podcasts became an enjoyable medium to use in teaching listening skill.

Died with or Died of? Development and Testing of a SARS CoV-2 Significance Score to Assess the Role of COVID-19 in the Deaths of Affected Patients

Since December 2019, a new form of coronavirus, SARS-CoV-2, has spread from China to the whole word, raising concerns regarding Coronavirus Disease 2019 (COVID-19) endangering public health and life. Over 1.5 million deaths related with COVID-19 have been recorded worldwide, with wide variations among countries affected by the pandemic and continuously growing numbers. The aim of this paper was to provide an overview of the literature cases of deaths involving COVID-19 and to evaluate the application of the COVID-19 Significance Score (CSS) in the classification of SARS CoV-2-related fatalities, comparing it with the Hamburg rating scale. The results obtained allowed us to highlight that CSS used after a complete accurate post-mortem examination, coupled to the retrieval of in vivo data, post-mortem radiology, histology and toxicology, as well as to additional required analyses (e.g., electronic microscopy) is a useful and concise tool in the assessment of the cause of death and the role played by this virus. A shared use of this scale might hopefully lower the inhomogeneities in forensic evaluation of SARS CoV-2-related fatalities.