Experimentation Investigation of Hard facing Layer by MMAW on Alloy Steel

The wearing of metal parts might be defined as a gradual decay or breakdown of the metal. When a part becomes so deformed that it cannot perform adequately, it must be replaced or rebuilt. While the end results of wear are similar, the causes of wear are different. It is essential to understand the wear factors involved before making a hard surfacing product selection. It would be easy to select a surfacing alloy if all metal components were subjected to only one type of wear. However, a metal part is usually worn by combinations of two or more types of wear. This makes an alloy selection considerably more complicated. A hard surfacing alloy should be chosen as a compromise between each wear factor. The initial focus should centre on the primary wear factor and then the secondary wear factor(s) should be examined. For example: upon examining a worn metal part, it is determined that the primary wear factor is abrasion and the secondary wear factor is light impact. The surfacing alloy chosen should have very good abrasion resistance but also have a fair amount of impact resistance. Keywords: Welding, Hard Facing Electrodes, Alloys, Afrox 300.

Experimental analysis of radially resolved dynamic inflow effects due to pitch steps

The dynamic inflow effect denotes the unsteady aerodynamic response to fast changes in rotor loading due to a gradual adaption of the wake. This does lead to load overshoots. The objective of the paper was to increase the understanding of that effect based on pitch step experiments on a 1.8 m diameter model wind turbine, which are performed in the large open jet wind tunnel of ForWind – University of Oldenburg. The flow in the rotor plane is measured with a 2D laser Doppler anemometer, and the dynamic wake induction factor transients in axial and tangential direction are extracted. Further, integral load measurements with strain gauges and hot-wire measurements in the near and close far wake are performed. The results show a clear gradual decay of the axial induction factors after a pitch step, giving the first direct experimental evidence of dynamic inflow due to pitch steps. Two engineering models are fitted to the induction factor transients to further investigate the relevant time constants of the dynamic inflow process. The radial dependency of the axial induction time constants as well as the dependency on the pitch direction is discussed. It is confirmed that the nature of the dynamic inflow decay is better described by two rather than only one time constant. The dynamic changes in wake radius are connected to the radial dependency of the axial induction transients. In conclusion, the comparative discussion of inductions, wake deployment and loads facilitate an improved physical understanding of the dynamic inflow process for wind turbines. Furthermore, these measurements provide a new detailed validation case for dynamic inflow models and other types of simulations.

Ontogeny in the steinmanellines (Bivalvia: Trigoniida): an intra- and interspecific appraisal using the Early Cretaceous faunas from the Neuquén Basin as a case study

Despite the paleontological relevance and paleobiological interest of trigoniid bivalves, our knowledge of their ontogeny—an aspect of crucial evolutionary importance—remains limited. Here, we assess the intra- and interspecific ontogenetic variations exhibited by the genus Steinmanella Crickmay (Myophorellidae: Steinmanellinae) during the early Valanginian–late Hauterivian of Argentina and explore some of their implications. The (ontogenetic) allometric trajectories of seven species recognized for this interval were estimated from longitudinal data using 3D geometric morphometrics, segmented regressions, and model selection tools, and then compared using trajectory analysis and allometric spaces. Our results show that within-species shell shape variation describes biphasic ontogenetic trajectories, decoupled from ontogenetic changes shown by sculpture, with a gradual decay in magnitude as ontogeny progresses. The modes of change characterizing each phase (crescentic growth and anteroposterior elongation, respectively) are conserved across species, thus representing a feature of Steinmanella ontogeny; its evolutionary origin is inferred to be a consequence of the rate modification and allometric repatterning of the ancestral ontogeny. Among species, trajectories are more variable during early ontogenetic stages, becoming increasingly conservative at later stages. Trajectories’ general orientation allows recognition of two stratigraphically consecutive groups of species, hinting at a potentially higher genus-level diversity in the studied interval. In terms of functional morphology, juveniles had a morphology more suited for active burrowing than adults, whose features are associated with a sedentary lifestyle. The characteristic disparity of trigoniids could be related to the existence of an ontogenetic period of greater shell malleability betrayed by the presence of crescentic shape change.

The Potential Role of Cytokines and Growth Factors in the Pathogenesis of Alzheimer’s Disease

Alzheimer’s disease (AD) is one of the most prominent neurodegenerative diseases, which impairs cognitive function in afflicted individuals. AD results in gradual decay of neuronal function as a consequence of diverse degenerating events. Several neuroimmune players (such as cytokines and growth factors that are key players in maintaining CNS homeostasis) turn aberrant during crosstalk between the innate and adaptive immunities. This aberrance underlies neuroinflammation and drives neuronal cells toward apoptotic decline. Neuroinflammation involves microglial activation and has been shown to exacerbate AD. This review attempted to elucidate the role of cytokines, growth factors, and associated mechanisms implicated in the course of AD, especially with neuroinflammation. We also evaluated the propensities and specific mechanism(s) of cytokines and growth factors impacting neuron upon apoptotic decline and further shed light on the availability and accessibility of cytokines across the blood-brain barrier and choroid plexus in AD pathophysiology. The pathogenic and the protective roles of macrophage migration and inhibitory factors, neurotrophic factors, hematopoietic-related growth factors, TAU phosphorylation, advanced glycation end products, complement system, and glial cells in AD and neuropsychiatric pathology were also discussed. Taken together, the emerging roles of these factors in AD pathology emphasize the importance of building novel strategies for an effective therapeutic/neuropsychiatric management of AD in clinics.

On the Alber equation for shoaling water waves

The problem of unidirectional shoaling of a water-wave field with a narrow energy spectrum is treated by using a new Alber equation. The stability of the linear stationary solution to small non-stationary disturbances is analysed; and numerical solutions for its subsequent long-distance evolution are presented. The results quantify the physics which causes the gradual decay in the probability of freak-wave occurrence, when moving from deep to shallow coastal waters.

The Potential Role of Cytokines and Growth Factors in the Pathogenesis of Alzheimer’s Disease

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized mainly by the gradual decay in neuronal function as a consequence of diverse degenerating events primarily including mitochondria dysfunction and cascades of neuro-immune reactions. Besides the acquired harmful reactive oxygen species (ROS), neurotoxins, and amyloid-beta (Aβ) and TAU pathologies in neurons, accumulating evidence with time underlined the roles of cytokines and growth factors in the AD pathogenesis. It may help us in evaluating the propensities and specific mechanism(s) of cytokines and factors impacting neuron upon apoptotic decline. Proinflammatory cytokines often induce inflammation in AD and AD-like pathogenesis in response to the apoptotic scenarios where some growth factors are involved in cytokinetic reactions to activate microglia and causing inflammation in AD. In this report, we comprehensively reviewed role of cytokines and chemokines in immune response to AD and neuropsychiatry. We provided insights into the neuroinflammation and the role of diverse factors including the pro-/anti-inflammatory cytokines, APP, TAU phosphorylation, glycation end products, complement system, and the role of glial cells. Also, we discussed the pathogenic and protective role of macrophage migration inhibitory factors, choroid plexus-, neurotrophic- and hematopoietic -related growth factors in AD. We further shed light on the availability and accessibility of the cytokines across the blood-brain barrier in AD pathophysiology. Taken together, the emerging role of these factors in AD pathology emphasized the importance of building novel strategies for an effective therapeutic/neuropsychiatric management of AD in clinics.

Experimental analysis of radially resolved dynamic inflow effects due to pitch steps

The dynamic inflow effect denotes the unsteady aerodynamic response to fast changes in rotor loading due to a gradual adaption of the wake. This does lead to load overshoots. The objective of the paper was to increase the understanding of that effect based on pitch step experiments on a 1.8 m diameter model wind turbine, which we performed in the large open jet wind tunnel of ForWind – University of Oldenburg. We measured the flow in the rotor plane with a 2D Laser Doppler Anemometer and were able to extract the dynamic wake induction factor transients in axial and tangential direction. Further, integral load measurements with strain gauges and hot wire measurements in the near and close far wake were performed. Our results show a clear gradual decay of the axial induction factors after a pitch step, giving the first direct experimental evidence of dynamic inflow due to pitch steps. We fitted two engineering models to the induction factor transients to further investigate the relevant time constants of the dynamic inflow process.We discussed the radial dependency of the axial induction time constants as well as the dependency on the pitch direction. We confirmed that the nature of the dynamic inflow decay is better described by two rather than only one time constant. The dynamic changes in wake radius were connected to the radial dependency of the axial induction transients. In conclusion, the comparative discussion of inductions, wake deployment and loads facilitated the improved physical understanding of the dynamic inflow process for wind turbines. Furthermore, these measurements provide a new detailed validation case for dynamic inflow models and other types of simulations.

Revisiting the “Inhabited Space” of English Country House in Sarah Waters’s The Little Stranger

The English Country House happens to be one of the most iconic topoi in English literary studies. Since narratologists have long privileged time over space, narrative space remained a relatively unexplored territory until the twentieth century, which intensified the interest in the house as the thematic fulcrum of literary works. British novelist Sarah Waters’s first venture into the realm of the sub-genre of English Country House fiction, The Little Stranger (2009) is a befitting discourse that appropriates the poetics of manorial space. Hundreds Hall, the Warwickshire seat of the Ayreses, encapsulates many roles as the epicentre of the story and as a powerful symbol of the gradual decay of English aristocracy in the post-World War II Britain. The article will try to incorporate Gaston Bachelard’s spatial criticism elaborated in his The Poetics of Space (1958) and the concept of heterotopia by Foucault for the interpretation/ (s) of the narrative. The study seeks to locate Bachelard’s bourgeoisie points of view, which the author subverts by portraying the rise of the proletariat. The focus of the article is to highlight the ingenuity of Waters’s creative process, which resorts to the genre of English Country House fiction to capture the condition of British aristocrats in a time of crises.

Dynamic versus Continuous Interventions: Optimizing Lockdown Policies for COVID-19

In the context of the ongoing COVID-19 pandemic, while millions of people await the administration of a vaccine, social distancing remains the leading approach towards the effect commonly known as “flattening the curve” of infections. Over the last year, governmental administrations throughout the globe have implemented various lockdown policies in hopes of slowing down the transmission of the disease. However, the current lack of consensus on when and how these policies should be implemented reflects the need for further studies regarding these questions. In this paper, we tackle the issue of lockdown policy management, in particular in terms of lockdown placement (how often, when, and how long these periods should be), in order to minimize the peak of infections in a specific population. We introduce a novel combination of classic mathematical disease modelling using the equation-based SEIR model, and Evolutionary Strategies (ES) for optimizing the peak of infections. The method is evaluated using data collected in different countries, and a particular focus is placed on the study of the effect of specific model parameters on lockdown optimization, such as the transmission rate (β), of which 4 alternative modelling functions have been proposed and analyzed. Our results indicate that this transmission rate parameter significantly influences the resulting optimal strategies. In particular, the presence of a gradual decay of the rate of transmission during lockdown leads to longer, more sparsely placed confinement periods while an abrupt, instantaneous drop in the amount of contacts per person favors shorter but more frequent lockdowns. Although these results are limited by the scope of action provided by the simplicity of the SEIR model, they suggest that the influence of the evolution of the rate of transmission along the disease should be assessed in further studies with alternative optimization strategies (agent-based) and models (SEIRSHUD).

Evidence of chromospheric molecular hydrogen emission in a solar flare observed by the IRIS satellite

We have carried out the first comprehensive investigation of enhanced line emission from molecular hydrogen, H2 at 1333.79 Å, observed at flare ribbons in SOL2014-04-18T13:03. The cool H2 emission is known to be fluorescently excited by Si iv 1402.77 Å UV radiation and provides a unique view of the temperature minimum region (TMR). Strong H2 emission was observed when the Si iv 1402.77 Å emission was bright during the flare impulsive phase and gradual decay phase, but it dimmed during the GOES peak. H2 line broadening showed non-thermal speeds in the range 7-18 $\rm {km~s}^{-1}$, possibly corresponding to turbulent plasma flows. Small red (blue) shifts, up to 1.8 (4.9) $\rm {km~s}^{-1}$ were measured. The intensity ratio of Si iv 1393.76 Å and Si iv 1402.77 Å confirmed that plasma was optically thin to Si iv (where the ratio = 2) during the impulsive phase of the flare in locations where strong H2 emission was observed. In contrast, the ratio differs from optically thin value of 2 in parts of ribbons, indicating a role for opacity effects. A strong spatial and temporal correlation between H2 and Si iv emission was evident supporting the notion that fluorescent excitation is responsible.